STAT3 but not STAT1 is required for astrocyte differentiation

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Hong, Seulgi ^a   Song, Mi Ryoung ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; BINDING AFFINITY; BINDING SITE; CELL ASSAY; CELL COUNT; CELL DIFFERENTIATION; CHICK; CONTROLLED STUDY; ELECTROPORATION; FEMALE; GLIA CELL; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WHITE MATTER;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; CHICK EMBRYO; EMBRYO, MAMMALIAN; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; INTEGRASES; LUCIFERASES; MALE; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEUROGLIA; PROMOTER REGIONS, GENETIC; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR;

EID: 84899842572     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086851     Document Type: Article

References (46)

1. Deverman BE, Patterson PH (2009) Cytokines and CNS development. Neuron 64: 61-78.
2. Koblar SA, Turnley AM, Classon BJ, Reid KL, Ware CB, et al. (1998) Neural precursor differentiation into astrocytes requires signaling through the leukemia inhibitory factor receptor. Proc Natl Acad Sci U S A 95: 3178-3181. (Pubitemid 28135875)
3. Nakashima K, Wiese S, Yanagisawa M, Arakawa H, Kimura N, et al. (1999) Developmental requirement of gp130 signaling in neuronal survival and astrocyte differentiation. J Neurosci 19: 5429-5434. (Pubitemid 29300208)
4. Levy DE, Darnell JE, Jr. (2002) Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 3: 651-662. (Pubitemid 34987786)
5. Stancato LF, David M, Carter-Su C, Larner AC, Pratt WB (1996) Preassociation of STAT1 with STAT2 and STAT3 in separate signalling complexes prior to cytokine stimulation. J Biol Chem 271: 4134-4137. (Pubitemid 26070511)
6. Novak U, Mui A, Miyajima A, Paradiso L (1996) Formation of STAT5-containing DNA binding complexes in response to colony-stimulating factor-1 and platelet-derived growth factor. J Biol Chem 271: 18350-18354. (Pubitemid 26322688)
7. Bonni A, Sun Y, Nadal-Vicens M, Bhatt A, Frank DA, et al. (1997) Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway. Science 278: 477-483. (Pubitemid 27454434)
8. Regis G, Pensa S, Boselli D, Novelli F, Poli V (2008) Ups and downs: the STAT1:STAT3 seesaw of Interferon and gp130 receptor signalling. Semin Cell Dev Biol 19: 351-359.
9. Thyrell L, Arulampalam V, Hjortsberg L, Farnebo M, Grander D, et al. (2007) Interferon alpha induces cell death through interference with interleukin 6 signaling and inhibition of STAT3 activity. Exp Cell Res 313: 4015-4024. (Pubitemid 47632542)
10. Ho HH, Ivashkiv LB (2006) Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation. J Biol Chem 281: 14111-14118. (Pubitemid 43848338)
11. Meraz MA, White JM, Sheehan KC, Bach EA, Rodig SJ, et al. (1996) Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84: 431-442. (Pubitemid 26058568)
12. Sanz E, Hofer MJ, Unzeta M, Campbell IL (2008) Minimal role for STAT1 in interleukin-6 signaling and actions in the murine brain. Glia 56: 190-199. (Pubitemid 350292311)
13. Barnabe-Heider F, Wasylnka JA, Fernandes KJ, Porsche C, Sendtner M, et al. (2005) Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1. Neuron 48: 253-265. (Pubitemid 41476359)
14. Maritano D, Sugrue ML, Tininini S, Dewilde S, Strobl B, et al. (2004) The STAT3 isoforms alpha and beta have unique and specific functions. Nat Immunol 5: 401-409. (Pubitemid 38500089)
15. Herrmann JE, Imura T, Song B, Qi J, Ao Y, et al. (2008) STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. J Neurosci 28: 7231-7243.
16. Takeda K, Kaisho T, Yoshida N, Takeda J, Kishimoto T, et al. (1998) Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J Immunol 161: 4652-4660. (Pubitemid 28492039)
17. Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, et al. (1999) Stat3 as an oncogene. Cell 98: 295-303. (Pubitemid 29380565)
18. He F, Ge W, Martinowich K, Becker-Catania S, Coskun V, et al. (2005) A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis. Nat Neurosci 8: 616-625. (Pubitemid 40594203)
19. Schaefer LK, Wang S, Schaefer TS (1999) c-Src activates the DNA binding and transcriptional activity of Stat3 molecules: serine 727 is not required for transcriptional activation under certain circumstances. Biochem Biophys Res Commun 266: 481-487. (Pubitemid 30028693)
20. Bromberg JF, Darnell JE, Jr. (1999) Potential roles of Stat1 and Stat3 in cellular transformation. Cold Spring Harb Symp Quant Biol 64: 425-428. (Pubitemid 30329307)
21. Caldenhoven E, van Dijk TB, Solari R, Armstrong J, Raaijmakers JA, et al. (1996) STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription. J Biol Chem 271: 13221-13227. (Pubitemid 26175904)
22. Song MR, Ghosh A (2004) FGF2-induced chromatin remodeling regulates CNTF-mediated gene expression and astrocyte differentiation. Nat Neurosci 7: 229-235.
23. Kinsella TM, Nolan GP (1996) Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Hum Gene Ther 7: 1405-1413. (Pubitemid 26293560)
24. Kang K, Song MR (2010) Diverse FGF receptor signaling controls astrocyte specification and proliferation. Biochem Biophys Res Commun 395: 324-329.
25. Kang K, Lee D, Hong S, Park SG, Song M-R (2013) The E3 ligase Mind bomb-1 (mib1) modulates Delta-Notch signaling to control neurogenesis and gliogenesis in the developing spinal cord. Journal of Biological Chemistry 288: 2580-2592.
26. Sato Y, Kasai T, Nakagawa S, Tanabe K, Watanabe T, et al. (2007) Stable integration and conditional expression of electroporated transgenes in chicken embryos. Dev Biol 305: 616-624. (Pubitemid 46686603)
27. Kang K, Lee D, Hong S, Park SG, Song MR (2013) The E3 ligase Mind bomb-1 (Mib1) modulates Delta-Notch signaling to control neurogenesis and gliogenesis in the developing spinal cord. J Biol Chem 288: 2580-2592.
28. Takizawa T, Nakashima K, Namihira M, Ochiai W, Uemura A, et al. (2001) DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Dev Cell 1: 749-758. (Pubitemid 33586130)
29. Deneen B, Ho R, Lukaszewicz A, Hochstim CJ, Gronostajski RM, et al. (2006) The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord. Neuron 52: 953-968. (Pubitemid 44909408)
30. Sriram K, Benkovic SA, Hebert MA, Miller DB, O'Callaghan JP (2004) Induction of gp130-related cytokines and activation of JAK2/STAT3 pathway in astrocytes precedes up-regulation of glial fibrillary acidic protein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of neurodegeneration: key signaling pathway for astrogliosis in vivo? J Biol Chem 279: 19936-19947. (Pubitemid 38623436)
31. Bonni A, Sun Y, Nadal-Vicens M, Bhatt A, Frank DA, et al. (1997) Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway. Science 278: 477-483. (Pubitemid 27454434)
32. Lai CF, Ripperger J, Morella KK, Wang Y, Gearing DP, et al. (1995) STAT3 and STAT5B are targets of two different signal pathways activated by hematopoietin receptors and control transcription via separate cytokine response elements. J Biol Chem 270: 23254-23257.
33. Hemmann U, Gerhartz C, Heesel B, Sasse J, Kurapkat G, et al. (1996) Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation. J Biol Chem 271: 12999-13007.
34. Collison LW, Delgoffe GM, Guy CS, Vignali KM, Chaturvedi V, et al. (2012) The composition and signaling of the IL-35 receptor are unconventional. Nat Immunol 13: 290-299.
35. Haan S, Keller JF, Behrmann I, Heinrich PC, Haan C (2005) Multiple reasons for an inefficient STAT1 response upon IL-6-type cytokine stimulation. Cell Signal 17: 1542-1550. (Pubitemid 41253993)
36. Tanner DC, Cherry JD, Mayer-Proschel M (2011) Oligodendrocyte progenitors reversibly exit the cell cycle and give rise to astrocytes in response to interferongamma. J Neurosci 31: 6235-6246.
37. He F, Ge W, Martinowich K, Becker-Catania S, Coskun V, et al. (2005) A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis. Nature neuroscience 8: 616-625. (Pubitemid 40594203)
38. Rajan P, McKay RD (1998) Multiple routes to astrocytic differentiation in the CNS. The Journal of neuroscience 18: 3620-3629. (Pubitemid 28225670)
39. Johe KK, Hazel TG, Muller T, Dugich-Djordjevic MM, McKay R (1996) Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes & development 10: 3129-3140. (Pubitemid 27020541)
40. Yan Y, Bian W, Xie Z, Cao X, Le Roux I, et al. (2004) Stat3 signaling is present and active during development of the central nervous system and eye of vertebrates. Developmental dynamics 231: 248-257. (Pubitemid 39238051)
41. Song M-R, Ghosh A (2004) FGF2-induced chromatin remodeling regulates CNTF-mediated gene expression and astrocyte differentiation. Nature neuroscience 7: 229-235. (Pubitemid 38280446)
42. Takizawa T, Nakashima K, Namihira M, Ochiai W, Uemura A, et al. (2001) DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Developmental cell 1: 749-758. (Pubitemid 33586130)
43. Deneen B, Ho R, Lukaszewicz A, Hochstim CJ, Gronostajski RM, et al. (2006) The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord. Neuron 52: 953-968. (Pubitemid 44909408)
44. Namihira M, Kohyama J, Semi K, Sanosaka T, Deneen B, et al. (2009) Committed neuronal precursors confer astrocytic potential on residual neural precursor cells. Developmental cell 16: 245-255.
45. Dewilde S, Vercelli A, Chiarle R, Poli V (2008) Of alphas and betas: distinct and overlapping functions of STAT3 isoforms. Front Biosci 13: 6501-6514.
46. Nakashima K, Yanagisawa M, Arakawa H, Kimura N, Hisatsune T, et al. (1999) Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science 284: 479-482. (Pubitemid 29289619)