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Volumn 587, Issue 11, 2013, Pages 1624-1629

Dlg5 interacts with the TGF-β receptor and promotes its degradation

Author keywords

Crohn's disease; Discs large homolog 5; Epithelial to mesenchymal transition; Protein degradation; TGF receptor

Indexed keywords

DISCS LARGE HOMOLOG 5; MEMBRANE ASSOCIATED GUANYLATE CYCLASE KINASE; SMAD ANCHOR FOR RECEPTOR ACTIVATION; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG;

EID: 84878248779     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.04.015     Document Type: Article
Times cited : (21)

References (32)
  • 1
    • 0031840135 scopus 로고    scopus 로고
    • Identification of a novel human homolog of the Drosophila dlg, P-dlg, specifically expressed in the gland tissues and interacting with p55
    • H. Nakamura Identification of a novel human homolog of the Drosophila dlg, P-dlg, specifically expressed in the gland tissues and interacting with p55 FEBS Lett. 433 1998 63 67
    • (1998) FEBS Lett. , vol.433 , pp. 63-67
    • Nakamura, H.1
  • 2
    • 42449099865 scopus 로고    scopus 로고
    • The Crohn's disease susceptibility gene DLG5 as a member of the CARD interaction network
    • F. Friedrichs The Crohn's disease susceptibility gene DLG5 as a member of the CARD interaction network J. Mol. Med. (Berl) 86 2008 423 432
    • (2008) J. Mol. Med. (Berl) , vol.86 , pp. 423-432
    • Friedrichs, F.1
  • 3
    • 0037821783 scopus 로고    scopus 로고
    • Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact
    • M. Wakabayashi, T. Ito, M. Mitsushima, S. Aizawa, K. Ueda, T. Amachi, and N. Kioka Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact J. Biol. Chem. 278 2003 21709 21714
    • (2003) J. Biol. Chem. , vol.278 , pp. 21709-21714
    • Wakabayashi, M.1    Ito, T.2    Mitsushima, M.3    Aizawa, S.4    Ueda, K.5    Amachi, T.6    Kioka, N.7
  • 4
    • 0036257343 scopus 로고    scopus 로고
    • Vinexin, CAP/ponsin, ArgBP2: A novel adaptor protein family regulating cytoskeletal organization and signal transduction
    • N. Kioka, K. Ueda, and T. Amachi Vinexin, CAP/ponsin, ArgBP2: a novel adaptor protein family regulating cytoskeletal organization and signal transduction Cell Struct. Funct. 27 2002 1 7
    • (2002) Cell Struct. Funct. , vol.27 , pp. 1-7
    • Kioka, N.1    Ueda, K.2    Amachi, T.3
  • 5
    • 34548167569 scopus 로고    scopus 로고
    • Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice
    • T. Nechiporuk, T.E. Fernandez, and V. Vasioukhin Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice Dev. Cell 13 2007 338 350
    • (2007) Dev. Cell , vol.13 , pp. 338-350
    • Nechiporuk, T.1    Fernandez, T.E.2    Vasioukhin, V.3
  • 6
    • 77953624553 scopus 로고    scopus 로고
    • Discs large 5 is required for polarization of citron kinase in mitotic neural precursors
    • Y. Chang, O. Klezovitch, R.S. Walikonis, V. Vasioukhin, and J.J. LoTurco Discs large 5 is required for polarization of citron kinase in mitotic neural precursors Cell Cycle 9 2010 1990 1997
    • (2010) Cell Cycle , vol.9 , pp. 1990-1997
    • Chang, Y.1    Klezovitch, O.2    Walikonis, R.S.3    Vasioukhin, V.4    Loturco, J.J.5
  • 7
    • 2442519456 scopus 로고    scopus 로고
    • Genetic variation in DLG5 is associated with inflammatory bowel disease
    • M. Stoll Genetic variation in DLG5 is associated with inflammatory bowel disease Nat. Genet. 36 2004 476 480
    • (2004) Nat. Genet. , vol.36 , pp. 476-480
    • Stoll, M.1
  • 10
    • 38349113447 scopus 로고    scopus 로고
    • Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts
    • B.L. Browning Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts J. Med. Genet. 45 2008 36 42
    • (2008) J. Med. Genet. , vol.45 , pp. 36-42
    • Browning, B.L.1
  • 11
    • 77249166049 scopus 로고    scopus 로고
    • Genetic association of DLG5 R30Q with familial and sporadic inflammatory bowel disease in men
    • Z. Lin Genetic association of DLG5 R30Q with familial and sporadic inflammatory bowel disease in men Dis. Markers 27 2009 193 201
    • (2009) Dis. Markers , vol.27 , pp. 193-201
    • Lin, Z.1
  • 12
    • 84859992632 scopus 로고    scopus 로고
    • Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells
    • T. Sezaki Role of Dlg5/lp-dlg, a membrane-associated guanylate kinase family protein, in epithelial-mesenchymal transition in LLc-PK1 renal epithelial cells PLoS One 7 2012 e35519
    • (2012) PLoS One , vol.7 , pp. 35519
    • Sezaki, T.1
  • 13
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • R. Derynck, and Y.E. Zhang Smad-dependent and Smad-independent pathways in TGF-beta family signalling Nature 425 2003 577 584
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 15
    • 0028603343 scopus 로고
    • TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type i receptors
    • P.J. Miettinen, R. Ebner, A.R. Lopez, and R. Derynck TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors J. Cell Biol. 127 1994 2021 2036
    • (1994) J. Cell Biol. , vol.127 , pp. 2021-2036
    • Miettinen, P.J.1    Ebner, R.2    Lopez, A.R.3    Derynck, R.4
  • 16
    • 79952791298 scopus 로고    scopus 로고
    • WAVE2 forms a complex with PKA and is involved in PKA enhancement of membrane protrusions
    • H. Yamashita, K. Ueda, and N. Kioka WAVE2 forms a complex with PKA and is involved in PKA enhancement of membrane protrusions J. Biol. Chem. 286 2011 3907 3914
    • (2011) J. Biol. Chem. , vol.286 , pp. 3907-3914
    • Yamashita, H.1    Ueda, K.2    Kioka, N.3
  • 17
    • 67651017495 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of vinexin in v-Src-transformed cells attenuates the affinity for vinculin
    • T. Umemoto, K. Tanaka, K. Ueda, and N. Kioka Tyrosine phosphorylation of vinexin in v-Src-transformed cells attenuates the affinity for vinculin Biochem. Biophys. Res. Commun. 387 2009 191 195
    • (2009) Biochem. Biophys. Res. Commun. , vol.387 , pp. 191-195
    • Umemoto, T.1    Tanaka, K.2    Ueda, K.3    Kioka, N.4
  • 18
    • 0034517389 scopus 로고    scopus 로고
    • Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation
    • P. Kavsak, R.K. Rasmussen, C.G. Causing, S. Bonni, H. Zhu, G.H. Thomsen, and J.L. Wrana Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation Mol. Cell 6 2000 1365 1375
    • (2000) Mol. Cell , vol.6 , pp. 1365-1375
    • Kavsak, P.1    Rasmussen, R.K.2    Causing, C.G.3    Bonni, S.4    Zhu, H.5    Thomsen, G.H.6    Wrana, J.L.7
  • 19
    • 0032428684 scopus 로고    scopus 로고
    • SARA, a FYVE domain protein that recruits Smad2 to the TGF beta receptor
    • T. Tsukazaki, T.A. Chiang, A.F. Davison, L. Attisano, and J.L. Wrana SARA, a FYVE domain protein that recruits Smad2 to the TGF beta receptor Cell 95 1998 779 791
    • (1998) Cell , vol.95 , pp. 779-791
    • Tsukazaki, T.1    Chiang, T.A.2    Davison, A.F.3    Attisano, L.4    Wrana, J.L.5
  • 20
    • 53349164136 scopus 로고    scopus 로고
    • The type i TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
    • A. Sorrentino The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner Nat. Cell Biol. 10 2008 1199 1207
    • (2008) Nat. Cell Biol. , vol.10 , pp. 1199-1207
    • Sorrentino, A.1
  • 21
    • 52049111663 scopus 로고    scopus 로고
    • TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta
    • M. Yamashita, K. Fatyol, C. Jin, X. Wang, Z. Liu, and Y.E. Zhang TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta Mol. Cell 31 2008 918 924
    • (2008) Mol. Cell , vol.31 , pp. 918-924
    • Yamashita, M.1    Fatyol, K.2    Jin, C.3    Wang, X.4    Liu, Z.5    Zhang, Y.E.6
  • 22
    • 4644312604 scopus 로고    scopus 로고
    • Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)
    • A. Komuro, T. Imamura, M. Saitoh, Y. Yoshida, T. Yamori, K. Miyazono, and K. Miyazawa Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1) Oncogene 23 2004 6914 6923
    • (2004) Oncogene , vol.23 , pp. 6914-6923
    • Komuro, A.1    Imamura, T.2    Saitoh, M.3    Yoshida, Y.4    Yamori, T.5    Miyazono, K.6    Miyazawa, K.7
  • 23
    • 0031587828 scopus 로고    scopus 로고
    • The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling
    • H. Hayashi The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling Cell 89 1997 1165 1173
    • (1997) Cell , vol.89 , pp. 1165-1173
    • Hayashi, H.1
  • 25
    • 0030611757 scopus 로고    scopus 로고
    • Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling
    • A. Nakao Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling Nature 389 1997 631 635
    • (1997) Nature , vol.389 , pp. 631-635
    • Nakao, A.1
  • 27
    • 76649108877 scopus 로고    scopus 로고
    • A design principle underlying the synchronization of oscillations in cellular systems
    • J.R. Kim, D. Shin, S.H. Jung, P. Heslop-Harrison, and K.H. Cho A design principle underlying the synchronization of oscillations in cellular systems J. Cell Sci. 123 2010 537 543
    • (2010) J. Cell Sci. , vol.123 , pp. 537-543
    • Kim, J.R.1    Shin, D.2    Jung, S.H.3    Heslop-Harrison, P.4    Cho, K.H.5
  • 28
    • 0036532226 scopus 로고    scopus 로고
    • Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability
    • J.E. Ferrell Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability Curr. Opin. Cell Biol. 14 2002 140 148
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 140-148
    • Ferrell, J.E.1
  • 29
    • 0030926004 scopus 로고    scopus 로고
    • Mechanism of TGFbeta receptor inhibition by FKBP12
    • Y.G. Chen, F. Liu, and J. Massague Mechanism of TGFbeta receptor inhibition by FKBP12 EMBO J. 16 1997 3866 3876
    • (1997) EMBO J. , vol.16 , pp. 3866-3876
    • Chen, Y.G.1    Liu, F.2    Massague, J.3
  • 30
    • 0027724228 scopus 로고
    • Transforming growth factor-beta 1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease
    • A.B. Kulkarni, and S. Karlsson Transforming growth factor-beta 1 knockout mice. a mutation in one cytokine gene causes a dramatic inflammatory disease Am. J. Pathol. 143 1993 3 9
    • (1993) Am. J. Pathol. , vol.143 , pp. 3-9
    • Kulkarni, A.B.1    Karlsson, S.2
  • 31
    • 27744485015 scopus 로고    scopus 로고
    • Post-transcriptional regulation of Smad7 in the gut of patients with inflammatory bowel disease
    • G. Monteleone Post-transcriptional regulation of Smad7 in the gut of patients with inflammatory bowel disease Gastroenterology 129 2005 1420 1429
    • (2005) Gastroenterology , vol.129 , pp. 1420-1429
    • Monteleone, G.1
  • 32
    • 84859439270 scopus 로고    scopus 로고
    • Phase i clinical trial of Smad7 knockdown using antisense oligonucleotide in patients with active Crohn's disease
    • G. Monteleone Phase I clinical trial of Smad7 knockdown using antisense oligonucleotide in patients with active Crohn's disease Mol. Ther. 20 2012 870 876
    • (2012) Mol. Ther. , vol.20 , pp. 870-876
    • Monteleone, G.1


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