Low-temperature plasma-induced antiproliferative effects on multi-cellular tumor spheroids

New Journal of Physics

Volumn 16, Issue , 2014, Pages

  Plewa, Joseph Marie ^a,b   Yousfi, Mohammed ^a,b   Frongia, Céline ^a,c   Eichwald, Olivier ^a,b   Ducommun, Bernard ^a,c,d   Merbahi, Nofel ^a,b   Lobjois, Valérie ^a,c  

^a UNIVERSITÉ DE TOULOUSE   (France)

^b Laboratoire Plasma et Conversion d'Energie   (France)

^c UPS   (France)

^d TOULOUSE UNIVERSITY HOSPITAL   (France)

Author keywords

antiproliferative effect; genotoxic and cytotoxic effects; low temperature plasma; multi cellular tumor spheroid; reactive oxygen species

Indexed keywords

AMINO ACIDS; CELL DEATH; CYTOTOXICITY; DAMAGE DETECTION; MEDICAL APPLICATIONS; OXYGEN; PLASMAS; TUMORS;

ANTIPROLIFERATIVE EFFECT; CYTOTOXIC EFFECTS; LOW TEMPERATURE PLASMAS; REACTIVE OXYGEN SPECIES; TUMOR SPHEROID;

TEMPERATURE;

EID: 84899821378     PISSN: 13672630     EISSN: None     Source Type: Journal    
DOI: 10.1088/1367-2630/16/4/043027     Document Type: Article

References (29)

1. Laroussi M 2002 Non-thermal decontamination of biological media by atmospheric pressure plasmas: review, analysis, and prospects EEE Trans. Plasma Sci. 30 1409-15
2. Heinlin J, Morfill G, Landthaler M, Stolz W, Isbary G, Zimmermann J, Shimizu T and Karrer S 2010 Plasma medicine: possible applications in dermatology J. Ger. Soc. Dermatology 8 968-76
3. Desmet T, Morent R, De Geyter N, Leys C, Schacht E and Dubruel P 2009 Nonthermal plasma technology as a versatile strategy for polymeric biomaterials surface modification: a review Biomacromolecules 10 2351-78
4. Fridman G, Friedman G, Gutsol A, Shekhter A B, Vasilets V N and Fridman A 2008 Applied plasma medicine Plasma Process. Polym. 5 503-33
5. Ogawa Y, Morikawa N, Ohkubo-Suzuki A, Miyoshi S, Arakawa H, Kita Y and Nishimura N 2005 An epoch-making application of discharge plasma phenomenon to gene-transfer Biotechnol. Bioeng. 92 865-70
6. Yousfi M, Merbahi N, Pathak A and Eichwald O 2014 Low-temperature plasmas at atmospheric pressure: toward new pharmaceutical treatments in medicine Fundam:. Clin. Pharmacology 28 123-5
7. Kong M G, Kroesen G, Morfill G, Nosenko T, Shimizu T, Dijk J V and Zimmermann J L 2009 Plasma medicine: an introductory review New J. Phys. 11 115012
8. Ishaq M, Evans M M and Ostrikov K K 2014 Effect of atmospheric gas plasmas on cancer cell signaling Int. J. Cancer 134 1517-28
9. Koritzer J, Boxhammer V, Schafer A, Shimizu T, Klampfl T G and Li Y F 2013 Restoration of sensitivity in chemo-resistant glioma cells by cold atmospheric plasma PLoS One 8 e64498
10. Vandamme M, Robert E, Lerondel S, Sarron V, Ries D, Dozias S et al 2012 ROS implication in a new antitumor strategy based on non-thermal plasma Int. J. Cancer 130 2185-94
11. Tuhvatulin A I, Sysolyatina E V, Scheblyakov D V, Logunov D Y, Vasiliev M M, Yurova M A et al 2012 Non-thermal Plasma Causes p53-Dependent Apoptosis in Human Colon Carcinoma Cells Acta Naturae 4 82-7
12. Ahn H J, Kim K, Kim G, moon E, Yang S S and Lee J S 2011 Atmospheric pressure plasma jet induces apoptosis involving mitocondria via generation of free radicals PLoS One 6 e28154
13. Keidar M, Walk R, Shashurin A, Srinivasan P, Sandler A, Dasgupta S, Ravi R, Guerrero-Preston R and Trink B 2011 Cold plasma selectivity and the possibility of a paradigm shift in cancer therapy Br J. Cancer 105 1295-301
14. Kim J Y, Kim S O, Wei Y and Li J 2010 A flexible cold micro-plasma jet using biocompatible dielectric tubes for cancer therapy Appl. Phys. Lett. 96 203701
15. Brulle L, Vandamme M, Ries D, Martel E, Robert E, Lerondel S, Trichet V, Richard S and Pouvesle J-M 2012 Effects of a non thermal plasma treatment alone or in combination with gemcitabine in a MIA PaCa2-luc orthotopic pancreatic carcinoma model PLoS One 7 e52653
16. Desoize B and Jardillier J 2000 Multicellular resistance: a paradigm for clinical resistance' Crit. Rev. Oncol. Hematol 36 193-207
17. Hirschhaeuser F, Menne H, Dittfeld C, West J, Mueller-Klieser W and Kunz-Schughart L A 2010 Multicellular tumor spheroids: an underestimated tool is catching up again J. Biotechnol. 148 3-15
18. Sutherland R M 1988 Cell and environment interactions in tumor microregions: the multicell spheroid model Science 240 177-84
19. Drasdo D and Höhme S 2005 A single-cell-based model of tumor growth in vitro: monolayers and spheroids Phys. Biol. 2 133-47
20. Drasdo D and Hoehme S 2012 Modeling the impact of granular embedding media, and pulling versus pushing cells on growing cell clones New J. Phys. 14 055025
21. Pampaloni F, Reynaud E G and Stelzer E H 2007 The third dimension bridges the gap between cell culture and live tissue Nat. Rev. Mol. Cell Biol. 8 839-45
22. Yousfi M, Eichwald O, Merbahi N and Jomaa N 2012 Analysis of ionization wave dynamics in low-temperature plasma jets from fluid modeling supported by experimental investigations Plasma Sources Sci. Technol. 21 045003
23. Ostrikov K, Neyts E C and Meyyappan M 2013 Plasma nanoscience: from nano-solids in plasmas to nano-plasmas in solids Adv. Phys. 62 113-224
24. Tani A, Ono Y, Fukui S, Ikawa S and Kitano K 2012 Free radicals induced in aqueous solution by non-contact atmospheric-pressure cold plasma App. Phy. Lett. 100 254103
25. Laurent J, Frongia C, Cazales M, Mondésert O, Ducommun B and Lobjois V 2013 Multicellular tumor spheroid models to explore cell cycle checkpoints in 3D BMC Cancer 13 73
26. Lobjois V, Frongia C, Jozan S, Truchet I and Valette 2009 A Cell cycle and apoptotic effects of SAHA are regulated by the cellular microenvironment in HCT116 multicellular tumour spheroids Eur. J. Cancer 45 2402-11
27. Kalghatgi S, Kelly C M, Cerchar E, Torabi B, Alekseev O, Fridman A, Friedman G and Azizkhan-Clifford J 2011 Effects of non-thermal plasma on mammalian cells PLoS One 6 e16270
28. Graves D B 2012 The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology J. Phys. D: Appl. Phys. 45 263001
29. Zhao S et al 2013 Atmospheric pressure room temperature plasma jets facilitate oxidative and nitrative stress and lead to endoplasmic reticulum stress dependent apoptosis in HepG2 cells PLoS One 8 e73665