Restoration of Sensitivity in Chemo - Resistant Glioma Cells by Cold Atmospheric Plasma

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Köritzer, Julia ^a   Boxhammer, Veronika ^a   Schäfer, Andrea ^b   Shimizu, Tetsuji ^a   Klämpfl, Tobias G ^a   Li, Yang Fang ^a   Welz, Christian ^c   Schwenk Zieger, Sabina ^c   Morfill, Gregor E ^a   Zimmermann, Julia L ^a   Schlegel, Jürgen ^b  

^a MAX PLANCK INSTITUT FÜR EXTRATERRESTRISCHE PHYSIK   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; TEMOZOLOMIDE;

ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER RESISTANCE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CLONOGENESIS; COLD ATMOSPHERIC PLASMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSTASIS; DNA DAMAGE; GLIOMA CELL; GROWTH INHIBITION; HUMAN; HUMAN CELL; PHYSICAL MEDICINE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION;

ADULT; ATMOSPHERE; BRAIN NEOPLASMS; CELL DEATH; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; DACARBAZINE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; G2 PHASE; GLIOMA; HUMANS; PLASMA GASES; TUMOR STEM CELL ASSAY;

EID: 84877980704     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064498     Document Type: Article

References (41)

1. Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, et al. (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996.
2. Villano JL, Seery TE, Bressler LR, (2009) Temozolomide in malignant gliomas: current use and future targets. Cancer Chemother Pharmacol 64: 647-655.
3. Danson SJ, Middleton MR, (2001) Temozolomide: a novel oral alkylating agent. Expert Rev Anticancer Ther 1: 13-19.
4. Gerson SL, (2002) Clinical relevance of MGMT in the treatment of cancer. J Clin Oncol 20: 2388-2399.
5. Sarkaria JN, Kitange GJ, James CD, Plummer R, Calvert H, et al. (2008) Mechanisms of chemoresistance to alkylating agents in malignant glioma. Clin Cancer Res 14: 2900-2908.
6. Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, et al. (2000) Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343: 1350-1354.
7. Paz MF, Yaya-Tur R, Rojas-Marcos I, Reynes G, Pollan M, et al. (2004) CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas. Clin Cancer Res 10: 4933-4938.
8. Weiler M, Hartmann C, Wiewrodt D, Herrlinger U, Gorlia T, et al. (2010) Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide. Int J Radiat Oncol Biol Phys 77: 670-676.
9. Weller M, Felsberg J, Hartmann C, Berger H, Steinbach JP, et al. (2009) Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol 27: 5743-5750.
10. Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, et al. (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol 10: 459-466.
11. Morfill GE, Shimizu T, Steffes B, Schmidt HU, (2009) Nosocomial infections-a new approach towards preventive medicine using plasmas. New Journal of Physics 11.
12. Maisch T, Shimizu T, Isbary G, Heinlin J, Karrer S, et al. (2012) Contact-Free Inactivation of Candida albicans Biofilms by Cold Atmospheric Air Plasma. Appl Environ Microbiol 78: 4242-4247.
13. Zimmermann JL, Dumler K, Shimizu T, Morfill GE, Wolf A, et al. (2011) Effects of cold atmospheric plasmas on adenoviruses in solution. Journal of Physics D-Applied Physics 44.
14. Hahnel M, von Woedtke T, Weltmann KD, (2010) Influence of the Air Humidity on the Reduction of Bacillus Spores in a Defined Environment at Atmospheric Pressure Using a Dielectric Barrier Surface Discharge. Plasma Processes and Polymers 7: 244-249.
15. Klampfl TG, Isbary G, Shimizu T, Li YF, Zimmermann JL, et al. (2012) Cold atmospheric air plasma sterilization against spores and other microorganisms of clinical interest. Appl Environ Microbiol.
16. Baxter HC, Campbell GA, Richardson PR, Jones AC, Whittle IR, et al. (2006) Surgical instrument decontamination: Efficacy of introducing an argon: oxygen RF gas-plasma cleaning step as part of the cleaning cycle for stainless steel instruments. Ieee Transactions on Plasma Science 34: 1337-1344.
17. Whittaker AG, Graham EM, Baxter RL, Jones AC, Richardson PR, et al. (2004) Plasma cleaning of dental instruments. Journal of Hospital Infection 56: 37-41.
18. Baxter HC, Campbell GA, Whittaker AG, Jones AC, Aitken A, et al. (2005) Elimination of transmissible spongiform encephalopathy infectivity and decontamination of surgical instruments by using radio-frequency gas-plasma treatment. J Gen Virol 86: 2393-2399.
19. Maisch T, Shimizu T, Li YF, Heinlin J, Karrer S, et al. (2012) Decolonisation of MRSA, S. aureus and E. coli by cold-atmospheric plasma using a porcine skin model in vitro. PLoS One 7: e34610.
20. Lademann O, Kramer A, Richter H, Patzelt A, Meinke MC, et al. (2011) Skin Disinfection by Plasma-Tissue Interaction: Comparison of the Effectivity of Tissue-Tolerable Plasma and a Standard Antiseptic. Skin Pharmacology and Physiology 24: 284-288.
21. Isbary G, Morfill G, Schmidt HU, Georgi M, Ramrath K, et al. (2010) A first prospective randomized controlled trial to decrease bacterial load using cold atmospheric argon plasma on chronic wounds in patients. Br J Dermatol 163: 78-82.
22. Isbary G, Heinlin J, Shimizu T, Zimmermann JL, Morfill G, et al. (2012) Successful and Safe Use of 2 Min Cold Atmospheric Argon Plasma in Chronic Wounds: Results of A Randomized Controlled Trial. Br J Dermatol.
23. Kim CH, Bahn JH, Lee SH, Kim GY, Jun SI, et al. (2010) Induction of cell growth arrest by atmospheric non-thermal plasma in colorectal cancer cells. Journal of Biotechnology 150: 530-538.
24. Kim CH, Kwon S, Bahn JH, Lee K, Jun SI, et al. (2010) Effects of atmospheric nonthermal plasma on invasion of colorectal cancer cells. Appl Phys Lett 96: 243701.
25. Sensenig R, Kalghatgi S, Cerchar E, Fridman G, Shereshevsky A, et al. (2011) Non-thermal plasma induces apoptosis in melanoma cells via production of intracellular reactive oxygen species. Ann Biomed Eng 39: 674-687.
26. Zucker SN, Zirnheld J, Bagati A, Disanto TM, Des Soye B, et al. (2012) Preferential induction of apoptotic cell death in melanoma cells as compared with normal keratinocytes using a non-thermal plasma torch. Cancer Biol Ther 13: 1299-1306.
27. Kim JY, Ballato J, Foy P, Hawkins T, Wei Y, et al. (2011) Apoptosis of lung carcinoma cells induced by a flexible optical fiber-based cold microplasma. Biosens Bioelectron 28: 333-338.
28. Vandamme M, Robert E, Lerondel S, Sarron V, Ries D, et al. (2011) ROS implication in a new antitumor strategy based on non-thermal plasma. Int J Cancer.
29. Ahn HJ, Kim KI, Kim G, Moon E, Yang SS, et al. (2011) Atmospheric-pressure plasma jet induces apoptosis involving mitochondria via generation of free radicals. PLoS One 6: e28154.
30. Keidar M, Walk R, Shashurin A, Srinivasan P, Sandler A, et al. (2011) Cold plasma selectivity and the possibility of a paradigm shift in cancer therapy. Br J Cancer 105: 1295-1301.
31. Kogelschatz U, (2003) Dielectric-barrier discharges: Their history, discharge physics, and industrial applications. Plasma Chemistry and Plasma Processing 23: 1-46.
32. Bobola MS, Tseng SH, Blank A, Berger MS, Silber JR, (1996) Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin. Clin Cancer Res 2: 735-741.
33. Carlson BL, Grogan PT, Mladek AC, Schroeder MA, Kitange GJ, et al. (2009) Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts. Int J Radiat Oncol Biol Phys 75: 212-219.
34. Zhang J, Stevens MF, Laughton CA, Madhusudan S, Bradshaw TD, (2010) Acquired resistance to temozolomide in glioma cell lines: molecular mechanisms and potential translational applications. Oncology 78: 103-114.
35. Hegi ME, Liu L, Herman JG, Stupp R, Wick W, et al. (2008) Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity. J Clin Oncol 26: 4189-4199.
36. Felsberg J, Thon N, Eigenbrod S, Hentschel B, Sabel MC, et al. (2011) Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas. Int J Cancer 129: 659-670.
37. Beier D, Schulz JB, Beier CP, (2011) Chemoresistance of glioblastoma cancer stem cells-much more complex than expected. Mol Cancer 10: 128.
38. Carmo A, Carvalheiro H, Crespo I, Nunes I, Lopes MC, (2011) Effect of temozolomide on the U-118 glioma cell line. Oncol Lett 2: 1165-1170.
39. Lee JJ, Kim BC, Park MJ, Lee YS, Kim YN, et al. (2011) PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation. Cell Death Differ 18: 666-677.
40. Ostermann S, Csajka C, Buclin T, Leyvraz S, Lejeune F, et al. (2004) Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients. Clin Cancer Res 10: 3728-3736.
41. Portnow J, Badie B, Chen M, Liu A, Blanchard S, et al. (2009) The neuropharmacokinetics of temozolomide in patients with resectable brain tumors: potential implications for the current approach to chemoradiation. Clin Cancer Res 15: 7092-7098.