Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Yasunaga, Masahiro ^a   Matsumura, Yasuhiro ^a  

^a NATIONAL CANCER CENTER HOSPITAL EAST   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ABCG2 PROTEIN, HUMAN; CARRIER PROTEIN; FLUOROURACIL; MEMBRANE PROTEIN; TAURINE TRANSPORTER; TUMOR PROTEIN;

ANIMAL; ARTICLE; CANCER STEM CELL; CELL SURVIVAL; COLORECTAL TUMOR; DISEASE MODEL; DRUG EFFECT; DRUG RESISTANCE; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SILENCING; GENETICS; HUMAN; METABOLISM; MOUSE; MULTIDRUG RESISTANCE; PATHOLOGY; PHENOTYPE; SIDE POPULATION CELL; SIGNAL TRANSDUCTION; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE, TUMOR; CELL SURVIVAL; COLORECTAL NEOPLASMS; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; FLUOROURACIL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE KNOCKDOWN TECHNIQUES; HETEROGRAFTS; HUMANS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; PHENOTYPE; SIDE-POPULATION CELLS; SIGNAL TRANSDUCTION;

EID: 84899819129     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep04852     Document Type: Article

References (28)

1. Siegel, R., Naishadham, D. & Jemal, A. Cancer statistics, 2013. CA Cancer J Clin. 63, 11-30 (2013).
2. Cersosimo, R. J. Management of advanced colorectal cancer, Part 2. Am J Health Syst Pharm. 70, 491-506 (2013).
3. Lambert, I. H. Regulation of the cellular content of the organic osmolyte taurine in mammalian cells. Neurochem Res. 29, 27-63 (2004).
4. Han, X., Patters, A. B., Jones, D. P., Zelikovic, I. & Chesney, R. W. The taurine transporter: mechanisms of regulation. Acta Physiol (Oxf). 187, 61-73 (2006).
5. Warskulat, U. et al. Phenotype of the taurine transporter knockout mouse. Methods Enzymol. 428, 439-58 (2007).
6. Ito, T. et al. Taurine depletion caused by knocking out the taurine transporter gene leasds to cardiomyopathy with cardiac atropy. J Mol Cell Cardiol. 44, 927-37 (2008).
7. Kaesler, S. et al. Effective T-cell recall responses require the taurine transporter Taut. Eur J Immunol. 42, 831-41 (2012).
8. Dean, M., Fojo, T. & Bates, S. Tumour stem cells and drug resistance. Nat Rev Cancer. 5, 275-84 (2005).
9. Longley, D. B., Harkin, D. P. & Johnston, P. G. 5-fluorouracil: mechanism of action and clinical strategies. Nat Rev Cancer. 3, 330-8 (2003).
10. Jordan, C. T., Guzman, M. L. & Noble, M. Cancer stem cells. N Engl J Med. 355, 1253-61 (355).
11. Zhou, S. et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med. 7, 1028-34 (2001).
12. Jonker, J. W. et al. Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice. Stem Cells. 23, 1059-65 (2005).
13. Blencowe, B. J. Alternative splicing: new insights from global analyses. Cell. 126, 37-47 (2006).
14. Hawkins, R. D., Hon, G. C. & Ren, B. Next-generation genomics: an integrative approach. Nat Rev Genet. 11, 476-86 (2010).
15. Haller, A. C. et al. Transcriptional profiling of degraded RNA in cryopreserved and fixed tissue samples obtained at autopsy. BMC Clin Pathol. 6, 9 (2006).
16. Wersinger, C., Rebel, G. & Lelong-Rebel, I. H. Detailed study of the different taurine uptake system of colon LoVo MDR and non-MDR cell lines. Amino Acids. 19, 667-85 (2000).
17. Tastesen, H. S. et al. Pinpointing differences in cisplatin-induced apoptosis in adherent and non-adherent cancer cells. Cell Physiol Biochem. 26, 809-20 (2010).
18. Yi, J. M. et al. Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. Cancer Res. 68, 8094-103 (2008).
19. Jones, P. A. et al. The epigenomics of cancer. Cell. 128, 683-92 (2007).
20. Grady, W. M. & Carethers, J. M. Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology. 135, 1079-99 (2008).
21. Gupta, P. B., Chaffer, C. L. & Weinberg, R. A. Cancer stem cells: mirage or reality? Nat Med. 15, 1010-2 (2009).
22. Saito, Y. et al. The inhibition of pancreatic cancer invasion-metastasis cascade in both cellular signal and blood coagulation cascade of tissue factor by its neutralisation antibody. Eur J Cancer. 47, 2230-9 (2011).
23. Koga, Y. et al. Detection of colorectal cancer cells from feces using quantitative real-time RT-PCR for colorectal cancer diagnosis. Cancer Sci. 99, 1977-83 (2008).
24. Yasunaga, M. et al. Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nat Biotechnol. 23, 1542-50 (2005).
25. Irizarry, R. A. et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 4, 249-64 (2003).
26. Dai, M. et al. Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res. 33, e175 (2005).
27. Gentleman, R. C. et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 5, R80 (2004).
28. Yasunaga, M., Manabe, S., Tarin, D. & Matsumura, Y. Tailored immunoconjugate therapy depending on a quality of tumor stroma. Cancer Sci. 104, 231-7 (2013).