메뉴 건너뛰기




Volumn 54, Issue 6, 2014, Pages 603-615

Topical microbicides and HIV prevention in the female genital tract

Author keywords

female genital tract; HIV prevention; microbicide; pre exposure prophylaxis; tenofovir gel

Indexed keywords

ACICLOVIR; CONTRACEPTIVE AGENT; DAPIVIRINE; EMTRICITABINE; ETHINYLESTRADIOL PLUS ETONOGESTREL; MARAVIROC; MICROBICIDE; NEVIRAPINE; PLACEBO; POLYANION; PRO 2000; SURFACTANT; TENOFOVIR; TENOFOVIR DISOPROXIL; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; TOPICAL ANTIINFECTIVE AGENT;

EID: 84899816995     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1002/jcph.292     Document Type: Article
Times cited : (21)

References (109)
  • 1
    • 85059670808 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention Updated 2014. Accessed January14, 2014
    • Centers for Disease Control and Prevention. HIV prevention. http://www.cdc.gov/hiv/basics/prevention.html. Updated 2014. Accessed January14, 2014.
    • HIV Prevention
  • 2
    • 33747253464 scopus 로고    scopus 로고
    • Gender power imbalance on women's capacity to negotiate self-protection against HIV/AIDS in Botswana and South Africa
    • Langen TT,. Gender power imbalance on women's capacity to negotiate self-protection against HIV/AIDS in Botswana and South Africa. Afr Health Sci. 2005; 5 (3): 188-197.
    • (2005) Afr Health Sci , vol.5 , Issue.3 , pp. 188-197
    • Langen, T.T.1
  • 3
    • 84896882326 scopus 로고    scopus 로고
    • World Health Organization (WHO) Updated 2014. Accessed January 4, 2014
    • World Health Organization (WHO). Gender women and health: Gender inequalities and HIV. http://www.who.int/gender/hiv-aids/en/. Updated 2014. Accessed January 4, 2014.
    • Gender Women and Health: Gender Inequalities and HIV
  • 4
    • 84864505868 scopus 로고    scopus 로고
    • Antiretroviral prophylaxis for HIV prevention in heterosexual men and women
    • Baeten JM, Donnell D, Ndase P, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012; 367 (5): 399-410.
    • (2012) N Engl J Med , vol.367 , Issue.5 , pp. 399-410
    • Baeten, J.M.1    Donnell, D.2    Ndase, P.3
  • 5
    • 84864527306 scopus 로고    scopus 로고
    • Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana
    • Thigpen MC, Kebaabetswe PM, Paxton LA, et al. Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana. N Engl J Med. 2012; 367 (5): 423-434.
    • (2012) N Engl J Med , vol.367 , Issue.5 , pp. 423-434
    • Thigpen, M.C.1    Kebaabetswe, P.M.2    Paxton, L.A.3
  • 6
    • 84864507852 scopus 로고    scopus 로고
    • Preexposure prophylaxis for HIV infection among African women
    • Van Damme L, Corneli A, Ahmed K, et al. Preexposure prophylaxis for HIV infection among African women. N Engl J Med. 2012; 367 (5): 411-422.
    • (2012) N Engl J Med , vol.367 , Issue.5 , pp. 411-422
    • Van Damme, L.1    Corneli, A.2    Ahmed, K.3
  • 7
    • 84878958898 scopus 로고    scopus 로고
    • Pre-exposure prophylaxis for HIV in women: Daily oral tenofovir, oral tenofovir/emtricitabine or vaginal tenofovir gel in the VOICE study (MTN 003)
    • Atlanta, GA, March 36:Abstract 26LB
    • Marrazzo J, Ramjee G, Nair G,. et al. Pre-exposure prophylaxis for HIV in women: daily oral tenofovir, oral tenofovir/emtricitabine or vaginal tenofovir gel in the VOICE study (MTN 003). 20th Conference on Retroviruses and Opportunistic Infections. 2013;Atlanta, GA, March 36:Abstract 26LB.
    • (2013) 20th Conference on Retroviruses and Opportunistic Infections
    • Marrazzo, J.1    Ramjee, G.2    Nair, G.3
  • 8
    • 84893298120 scopus 로고    scopus 로고
    • Foster City, CA 94404: Gilead Sciences, Inc
    • Truvada full prescribing information. Foster City, CA 94404: Gilead Sciences, Inc; 2012.
    • (2012) Truvada Full Prescribing Information
  • 9
    • 84857135720 scopus 로고    scopus 로고
    • Non-specific microbicide product development: Then and now
    • Romano JW, Robbiani M, Doncel GF, Moench T,. Non-specific microbicide product development: then and now. Curr HIV Res. 2012; 10 (1): 9-18.
    • (2012) Curr HIV Res , vol.10 , Issue.1 , pp. 9-18
    • Romano, J.W.1    Robbiani, M.2    Doncel, G.F.3    Moench, T.4
  • 10
    • 0026692821 scopus 로고
    • The effect of contraceptives containing nonoxynol-9 on the genital transmission of simian immunodeficiency virus in rhesus macaques
    • Miller CJ, Alexander NJ, Gettie A, Hendrickx AG, Marx PA,. The effect of contraceptives containing nonoxynol-9 on the genital transmission of simian immunodeficiency virus in rhesus macaques. Fertil Steril. 1992; 57 (5): 1126-1128.
    • (1992) Fertil Steril , vol.57 , Issue.5 , pp. 1126-1128
    • Miller, C.J.1    Alexander, N.J.2    Gettie, A.3    Hendrickx, A.G.4    Marx, P.A.5
  • 11
    • 0026684234 scopus 로고
    • Efficacy of nonoxynol 9 contraceptive sponge use in preventing heterosexual acquisition of HIV in Nairobi prostitutes
    • Kreiss J, Ngugi E, Holmes K, et al. Efficacy of nonoxynol 9 contraceptive sponge use in preventing heterosexual acquisition of HIV in Nairobi prostitutes. JAMA. 1992; 268 (4): 477-482.
    • (1992) JAMA , vol.268 , Issue.4 , pp. 477-482
    • Kreiss, J.1    Ngugi, E.2    Holmes, K.3
  • 12
    • 0027312868 scopus 로고
    • Barrier contraceptive use and HIV infection among high-risk women in Cameroon
    • Zekeng L, Feldblum PJ, Oliver RM, Kaptue L,. Barrier contraceptive use and HIV infection among high-risk women in Cameroon. AIDS. 1993; 7 (5): 725-731.
    • (1993) AIDS , vol.7 , Issue.5 , pp. 725-731
    • Zekeng, L.1    Feldblum, P.J.2    Oliver, R.M.3    Kaptue, L.4
  • 13
    • 0027164058 scopus 로고
    • A dosing study of nonoxynol-9 and genital irritation
    • Roddy RE, Cordero M, Cordero C, Fortney JA,. A dosing study of nonoxynol-9 and genital irritation. Int J STD AIDS. 1993; 4 (3): 165-170.
    • (1993) Int J STD AIDS , vol.4 , Issue.3 , pp. 165-170
    • Roddy, R.E.1    Cordero, M.2    Cordero, C.3    Fortney, J.A.4
  • 14
    • 0032552228 scopus 로고    scopus 로고
    • A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases
    • Roddy RE, Zekeng L, Ryan KA, Tamoufe U, Weir SS, Wong EL,. A controlled trial of nonoxynol 9 film to reduce male-to-female transmission of sexually transmitted diseases. N Engl J Med. 1998; 339 (8): 504-510.
    • (1998) N Engl J Med , vol.339 , Issue.8 , pp. 504-510
    • Roddy, R.E.1    Zekeng, L.2    Ryan, K.A.3    Tamoufe, U.4    Weir, S.S.5    Wong, E.L.6
  • 15
    • 0032485243 scopus 로고    scopus 로고
    • Safety evaluation of nonoxynol-9 gel in women at low risk of HIV infection
    • Van Damme L, Niruthisard S, Atisook R, et al. Safety evaluation of nonoxynol-9 gel in women at low risk of HIV infection. AIDS. 1998; 12 (4): 433-437.
    • (1998) AIDS , vol.12 , Issue.4 , pp. 433-437
    • Van Damme, L.1    Niruthisard, S.2    Atisook, R.3
  • 16
    • 0033965025 scopus 로고    scopus 로고
    • Safety of multiple daily applications of COL-1492, a nonoxynol-9 vaginal gel, among female sex workers. COL-1492 phase II study group
    • Van Damme L, Chandeying V, Ramjee G, et al. Safety of multiple daily applications of COL-1492, a nonoxynol-9 vaginal gel, among female sex workers. COL-1492 phase II study group. AIDS. 2000; 14 (1): 85-88.
    • (2000) AIDS , vol.14 , Issue.1 , pp. 85-88
    • Van Damme, L.1    Chandeying, V.2    Ramjee, G.3
  • 17
    • 0037190597 scopus 로고    scopus 로고
    • Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: A randomised controlled trial
    • Van Damme L, Ramjee G, Alary M, et al. Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial. Lancet. 2002; 360 (9338): 971-977.
    • (2002) Lancet , vol.360 , Issue.9338 , pp. 971-977
    • Van Damme, L.1    Ramjee, G.2    Alary, M.3
  • 18
    • 0018824754 scopus 로고
    • Studies of nonoxynol-9. I. The effect on the vaginas of rabbits and rats
    • Chvapil M, Droegemueller W, Owen JA, Eskelson CD, Betts K,. Studies of nonoxynol-9. I. The effect on the vaginas of rabbits and rats. Fertil Steril. 1980; 33 (4): 445-450.
    • (1980) Fertil Steril , vol.33 , Issue.4 , pp. 445-450
    • Chvapil, M.1    Droegemueller, W.2    Owen, J.A.3    Eskelson, C.D.4    Betts, K.5
  • 19
    • 0026196420 scopus 로고
    • The effects of frequent nonoxynol-9 use on the vaginal and cervical mucosa
    • Niruthisard S, Roddy RE, Chutivongse S,. The effects of frequent nonoxynol-9 use on the vaginal and cervical mucosa. Sex Transm Dis. 1991; 18 (3): 176-179.
    • (1991) Sex Transm Dis , vol.18 , Issue.3 , pp. 176-179
    • Niruthisard, S.1    Roddy, R.E.2    Chutivongse, S.3
  • 20
    • 4344602905 scopus 로고    scopus 로고
    • A randomized phase i vaginal safety study of three concentrations of C31G vs. Extra strength gynol II
    • Mauck CK, Weiner DH, Creinin MD, Barnhart KT, Callahan MM, Bax R,. A randomized phase I vaginal safety study of three concentrations of C31G vs. extra strength gynol II. Contraception. 2004; 70 (3): 233-240.
    • (2004) Contraception , vol.70 , Issue.3 , pp. 233-240
    • Mauck, C.K.1    Weiner, D.H.2    Creinin, M.D.3    Barnhart, K.T.4    Callahan, M.M.5    Bax, R.6
  • 22
    • 4344640104 scopus 로고    scopus 로고
    • A phase i comparative postcoital testing study of three concentrations of C31G
    • Mauck CK, Creinin MD, Barnhart KT, et al. A phase I comparative postcoital testing study of three concentrations of C31G. Contraception. 2004; 70 (3): 227-231.
    • (2004) Contraception , vol.70 , Issue.3 , pp. 227-231
    • Mauck, C.K.1    Creinin, M.D.2    Barnhart, K.T.3
  • 23
    • 0036848251 scopus 로고    scopus 로고
    • Safety of single daily use for one week of C31G HEC gel in women
    • Ballagh SA, Baker JM, Henry DM, Archer DF,. Safety of single daily use for one week of C31G HEC gel in women. Contraception. 2002; 66 (5): 369-375.
    • (2002) Contraception , vol.66 , Issue.5 , pp. 369-375
    • Ballagh, S.A.1    Baker, J.M.2    Henry, D.M.3    Archer, D.F.4
  • 24
    • 44349126694 scopus 로고    scopus 로고
    • SAVVY (C31G) gel for prevention of HIV infection in women: A phase 3, double-blind, randomized, placebo-controlled trial in Ghana
    • Peterson L, Nanda K, Opoku BK, et al. SAVVY (C31G) gel for prevention of HIV infection in women: a phase 3, double-blind, randomized, placebo-controlled trial in Ghana. PLoS ONE. 2007; 2 (12): e1312.
    • (2007) PLoS ONE , vol.2 , Issue.12
    • Peterson, L.1    Nanda, K.2    Opoku, B.K.3
  • 25
    • 41849087248 scopus 로고    scopus 로고
    • SAVVY vaginal gel (C31G) for prevention of HIV infection: A randomized controlled trial in Nigeria
    • Feldblum PJ, Adeiga A, Bakare R, et al. SAVVY vaginal gel (C31G) for prevention of HIV infection: a randomized controlled trial in Nigeria. PLoS ONE. 2008; 3 (1): e1474.
    • (2008) PLoS ONE , vol.3 , Issue.1
    • Feldblum, P.J.1    Adeiga, A.2    Bakare, R.3
  • 26
    • 79955099301 scopus 로고    scopus 로고
    • The rise and fall of polyanionic inhibitors of the human immunodeficiency virus type 1
    • Pirrone V, Wigdahl B, Krebs FC,. The rise and fall of polyanionic inhibitors of the human immunodeficiency virus type 1. Antiviral Res. 2011; 90 (3): 168-182.
    • (2011) Antiviral Res. , vol.90 , Issue.3 , pp. 168-182
    • Pirrone, V.1    Wigdahl, B.2    Krebs, F.C.3
  • 27
    • 57049091723 scopus 로고    scopus 로고
    • Efficacy of carraguard for prevention of HIV infection in women in South Africa: A randomised, double-blind, placebo-controlled trial
    • Skoler-Karpoff S, Ramjee G, Ahmed K, et al. Efficacy of carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial. Lancet. 2008; 372 (9654): 1977-1987.
    • (2008) Lancet , vol.372 , Issue.9654 , pp. 1977-1987
    • Skoler-Karpoff, S.1    Ramjee, G.2    Ahmed, K.3
  • 28
    • 0037334375 scopus 로고    scopus 로고
    • Need for a true placebo for vaginal microbicide efficacy trials
    • author reply 786.
    • Kilmarx PH, Paxton L,. Need for a true placebo for vaginal microbicide efficacy trials. Lancet. 2003; 361 (9359): 785-786. author reply 786.
    • (2003) Lancet , vol.361 , Issue.9359 , pp. 785-786
    • Kilmarx, P.H.1    Paxton, L.2
  • 29
    • 31444438410 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of a potential universal placebo designed for use in vaginal microbicide clinical trials
    • Tien D, Schnaare RL, Kang F, et al. In vitro and in vivo characterization of a potential universal placebo designed for use in vaginal microbicide clinical trials. AIDS Res Hum Retroviruses. 2005; 21 (10): 845-853.
    • (2005) AIDS Res Hum Retroviruses , vol.21 , Issue.10 , pp. 845-853
    • Tien, D.1    Schnaare, R.L.2    Kang, F.3
  • 30
    • 34547841571 scopus 로고    scopus 로고
    • Safety and acceptability of 6% cellulose sulfate vaginal gel applied four times per day for 14 days
    • Doh AS, Ngoh N, Roddy R, Lai JJ, Linton K, Mauck C,. Safety and acceptability of 6% cellulose sulfate vaginal gel applied four times per day for 14 days. Contraception. 2007; 76 (3): 245-249.
    • (2007) Contraception , vol.76 , Issue.3 , pp. 245-249
    • Doh, A.S.1    Ngoh, N.2    Roddy, R.3    Lai, J.J.4    Linton, K.5    Mauck, C.6
  • 31
    • 0035709299 scopus 로고    scopus 로고
    • Single and multiple exposure tolerance study of cellulose sulfate gel: A phase i safety and colposcopy study
    • Mauck C, Weiner DH, Ballagh S, et al. Single and multiple exposure tolerance study of cellulose sulfate gel: a phase I safety and colposcopy study. Contraception. 2001; 64 (6): 383-391.
    • (2001) Contraception , vol.64 , Issue.6 , pp. 383-391
    • Mauck, C.1    Weiner, D.H.2    Ballagh, S.3
  • 32
    • 27944510206 scopus 로고    scopus 로고
    • Expanded phase i safety and acceptability study of 6% cellulose sulfate vaginal gel
    • Malonza IM, Mirembe F, Nakabiito C, et al. Expanded phase I safety and acceptability study of 6% cellulose sulfate vaginal gel. AIDS. 2005; 19 (18): 2157-2163.
    • (2005) AIDS , vol.19 , Issue.18 , pp. 2157-2163
    • Malonza, I.M.1    Mirembe, F.2    Nakabiito, C.3
  • 33
    • 33646888228 scopus 로고    scopus 로고
    • Safety and acceptability of cellulose sulfate as a vaginal microbicide in HIV-infected women
    • El-Sadr WM, Mayer KH, Maslankowski L, et al. Safety and acceptability of cellulose sulfate as a vaginal microbicide in HIV-infected women. AIDS. 2006; 20 (8): 1109-1116.
    • (2006) AIDS , vol.20 , Issue.8 , pp. 1109-1116
    • El-Sadr, W.M.1    Mayer, K.H.2    Maslankowski, L.3
  • 34
    • 33745948610 scopus 로고    scopus 로고
    • Fourteen-day safety and acceptability study of 6% cellulose sulfate gel: A randomized double-blind phase i safety study
    • Schwartz JL, Mauck C, Lai JJ, et al. Fourteen-day safety and acceptability study of 6% cellulose sulfate gel: a randomized double-blind phase I safety study. Contraception. 2006; 74 (2): 133-140.
    • (2006) Contraception , vol.74 , Issue.2 , pp. 133-140
    • Schwartz, J.L.1    Mauck, C.2    Lai, J.J.3
  • 35
    • 0035705878 scopus 로고    scopus 로고
    • Cellulose sulfate: Tolerance and acceptability of penile application
    • Mauck C, Frezieres R, Walsh T, Robergeau K, Callahan M,. Cellulose sulfate: tolerance and acceptability of penile application. Contraception. 2001; 64 (6): 377-381.
    • (2001) Contraception , vol.64 , Issue.6 , pp. 377-381
    • Mauck, C.1    Frezieres, R.2    Walsh, T.3    Robergeau, K.4    Callahan, M.5
  • 36
    • 34250873859 scopus 로고    scopus 로고
    • Safety trial of the vaginal microbicide cellulose sulfate gel in HIV-positive men
    • Jespers V, Buve A, Van Damme L,. Safety trial of the vaginal microbicide cellulose sulfate gel in HIV-positive men. Sex Transm Dis. 2007; 34 (7): 519-522.
    • (2007) Sex Transm Dis , vol.34 , Issue.7 , pp. 519-522
    • Jespers, V.1    Buve, A.2    Van Damme, L.3
  • 37
    • 57049159412 scopus 로고    scopus 로고
    • Effectiveness of cellulose sulfate vaginal gel for the prevention of HIV infection: Results of a phase III trial in Nigeria
    • Halpern V, Ogunsola F, Obunge O, et al. Effectiveness of cellulose sulfate vaginal gel for the prevention of HIV infection: results of a phase III trial in Nigeria. PLoS ONE. 2008; 3 (11): e3784.
    • (2008) PLoS ONE , vol.3 , Issue.11
    • Halpern, V.1    Ogunsola, F.2    Obunge, O.3
  • 38
    • 48249154985 scopus 로고    scopus 로고
    • Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission
    • Van Damme L, Govinden R, Mirembe FM, et al. Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission. N Engl J Med. 2008; 359 (5): 463-472.
    • (2008) N Engl J Med , vol.359 , Issue.5 , pp. 463-472
    • Van Damme, L.1    Govinden, R.2    Mirembe, F.M.3
  • 39
    • 69149100237 scopus 로고    scopus 로고
    • Disruption of tight junctions by cellulose sulfate facilitates HIV infection: Model of microbicide safety
    • Mesquita PM, Cheshenko N, Wilson SS, et al. Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safety. J Infect Dis. 2009; 200 (4): 599-608.
    • (2009) J Infect Dis , vol.200 , Issue.4 , pp. 599-608
    • Mesquita, P.M.1    Cheshenko, N.2    Wilson, S.S.3
  • 40
    • 79954804509 scopus 로고    scopus 로고
    • Safety and effectiveness of BufferGel and 0. 5% PRO2000 gel for the prevention of HIV infection in women
    • Abdool Karim SS, Richardson BA, Ramjee G, et al. Safety and effectiveness of BufferGel and 0. 5% PRO2000 gel for the prevention of HIV infection in women. AIDS. 2011; 25 (7): 957-966.
    • (2011) AIDS , vol.25 , Issue.7 , pp. 957-966
    • Abdool Karim, S.S.1    Richardson, B.A.2    Ramjee, G.3
  • 41
    • 77958104207 scopus 로고    scopus 로고
    • PRO2000 vaginal gel for prevention of HIV-1 infection (microbicides development programme 301): A phase 3, randomised, double-blind, parallel-group trial
    • McCormack S, Ramjee G, Kamali A, et al. PRO2000 vaginal gel for prevention of HIV-1 infection (microbicides development programme 301): a phase 3, randomised, double-blind, parallel-group trial. Lancet. 2010; 376 (9749): 1329-1337.
    • (2010) Lancet , vol.376 , Issue.9749 , pp. 1329-1337
    • McCormack, S.1    Ramjee, G.2    Kamali, A.3
  • 42
    • 0036100217 scopus 로고    scopus 로고
    • AIDS models: Microbicides could learn from vaccines
    • Shattock RJ, Doms RW,. AIDS models: microbicides could learn from vaccines. Nat Med. 2002; 8 (5): 425.
    • (2002) Nat Med , vol.8 , Issue.5 , pp. 425
    • Shattock, R.J.1    Doms, R.W.2
  • 43
    • 48249121565 scopus 로고    scopus 로고
    • Whither or wither microbicides?
    • Grant RM, Hamer D, Hope T, et al. Whither or wither microbicides?. Science. 2008; 321 (5888): 532-534.
    • (2008) Science , vol.321 , Issue.5888 , pp. 532-534
    • Grant, R.M.1    Hamer, D.2    Hope, T.3
  • 44
    • 84855584286 scopus 로고    scopus 로고
    • The use of nonhuman primate models of HIV infection for the evaluation of antiviral strategies
    • Van Rompay KK,. The use of nonhuman primate models of HIV infection for the evaluation of antiviral strategies. AIDS Res Hum Retroviruses. 2012; 28 (1): 16-35.
    • (2012) AIDS Res Hum Retroviruses , vol.28 , Issue.1 , pp. 16-35
    • Van Rompay, K.K.1
  • 45
    • 84861709262 scopus 로고    scopus 로고
    • Mucosal HIV-1 transmission and prevention strategies in BLT humanized mice
    • Denton PW, Garcia JV,. Mucosal HIV-1 transmission and prevention strategies in BLT humanized mice. Trends Microbiol. 2012; 20 (6): 268-274.
    • (2012) Trends Microbiol , vol.20 , Issue.6 , pp. 268-274
    • Denton, P.W.1    Garcia, J.V.2
  • 46
    • 84886711813 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics in HIV prevention; Current status and future directions: A summary of the DAIDS and BMGF sponsored think tank on pharmacokinetics (PK)/pharmacodynamics (PD) in HIV prevention
    • Romano J, Kashuba A, Becker S, et al. Pharmacokinetics and pharmacodynamics in HIV prevention; current status and future directions: a summary of the DAIDS and BMGF sponsored think tank on pharmacokinetics (PK)/pharmacodynamics (PD) in HIV prevention. AIDS Res Hum Retroviruses. 2013; 29 (11): 1418-1427.
    • (2013) AIDS Res Hum Retroviruses , vol.29 , Issue.11 , pp. 1418-1427
    • Romano, J.1    Kashuba, A.2    Becker, S.3
  • 47
    • 77955930318 scopus 로고    scopus 로고
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    • Abdool Karim Q, Abdool Karim SS, Frohlich JA, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010; 329 (5996): 1168-1174.
    • (2010) Science , vol.329 , Issue.5996 , pp. 1168-1174
    • Abdool Karim, Q.1    Abdool Karim, S.S.2    Frohlich, J.A.3
  • 49
    • 84899866633 scopus 로고    scopus 로고
    • CONRAD Updated. Accessed December 11, 2013.
    • CONRAD. Tenofovir gel overview. http://www.conrad.org/tenofovir.html. Updated 2013. Accessed December 11, 2013.
    • (2013) Tenofovir Gel Overview
  • 51
    • 29744439858 scopus 로고    scopus 로고
    • The prospect for RT inhibitors as topical microbicides
    • London, England:Abstract MMM-03
    • Wainberg M,. The prospect for RT inhibitors as topical microbicides. Microbicides 2004 Conference. 2004;London, England:Abstract MMM-03.
    • (2004) Microbicides 2004 Conference
    • Wainberg, M.1
  • 52
    • 84859726964 scopus 로고    scopus 로고
    • A drug evaluation of 1% tenofovir gel and tenofovir disoproxil fumarate tablets forthe prevention of HIV infection
    • Gengiah TN, Baxter C, Mansoor LE, Kharsany AB, Abdool Karim SS,. A drug evaluation of 1% tenofovir gel and tenofovir disoproxil fumarate tablets forthe prevention of HIV infection. Expert Opin Investig Drugs. 2012; 21 (5): 695-715.
    • (2012) Expert Opin Investig Drugs , vol.21 , Issue.5 , pp. 695-715
    • Gengiah, T.N.1    Baxter, C.2    Mansoor, L.E.3    Kharsany, A.B.4    Abdool Karim, S.S.5
  • 53
    • 84863115647 scopus 로고    scopus 로고
    • Durable protection from vaginal simian-human immunodeficiency virus infection in macaques by tenofovir gel and its relationship to drug levels in tissue
    • Dobard C, Sharma S, Martin A, et al. Durable protection from vaginal simian-human immunodeficiency virus infection in macaques by tenofovir gel and its relationship to drug levels in tissue. J Virol. 2012; 86 (2): 718-725.
    • (2012) J Virol , vol.86 , Issue.2 , pp. 718-725
    • Dobard, C.1    Sharma, S.2    Martin, A.3
  • 54
    • 84868474359 scopus 로고    scopus 로고
    • RMP-02/MTN-006: A phase 1 rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of tenofovir 1% gel compared with oral tenofovir disoproxil fumarate
    • Anton PA, Cranston RD, Kashuba A, et al. RMP-02/MTN-006: a phase 1 rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of tenofovir 1% gel compared with oral tenofovir disoproxil fumarate. AIDS Res Hum Retroviruses. 2012; 28 (11): 1412-1421.
    • (2012) AIDS Res Hum Retroviruses , vol.28 , Issue.11 , pp. 1412-1421
    • Anton, P.A.1    Cranston, R.D.2    Kashuba, A.3
  • 55
    • 84899834943 scopus 로고    scopus 로고
    • Tenofovir diphosphate concentration-response relationship for HIV prevention in vaginal tissue
    • Boston, MA: Abstract 512
    • Nicol M, Emerson C, Nelson J,. et al. Tenofovir diphosphate concentration-response relationship for HIV prevention in vaginal tissue. 21st Conference on Retroviruses and Opportunistic Infections. 2014;Boston, MA: Abstract 512.
    • (2014) 21st Conference on Retroviruses and Opportunistic Infections
    • Nicol, M.1    Emerson, C.2    Nelson, J.3
  • 56
    • 33645422725 scopus 로고    scopus 로고
    • Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women
    • Mayer KH, Maslankowski LA, Gai F, et al. Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women. AIDS. 2006; 20 (4): 543-551.
    • (2006) AIDS , vol.20 , Issue.4 , pp. 543-551
    • Mayer, K.H.1    Maslankowski, L.A.2    Gai, F.3
  • 58
    • 84864385142 scopus 로고    scopus 로고
    • Reformulated tenofovir gel for use as a dual compartment microbicide
    • Dezzutti CS, Rohan LC, Wang L, et al. Reformulated tenofovir gel for use as a dual compartment microbicide. J Antimicrob Chemother. 2012; 67 (9): 2139-2142.
    • (2012) J Antimicrob Chemother , vol.67 , Issue.9 , pp. 2139-2142
    • Dezzutti, C.S.1    Rohan, L.C.2    Wang, L.3
  • 59
    • 84875746052 scopus 로고    scopus 로고
    • A phase 1 randomized, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007)
    • McGowan I, Hoesley C, Cranston RD, et al. A phase 1 randomized, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007). PLoS ONE. 2013; 8 (4): e60147.
    • (2013) PLoS ONE , vol.8 , Issue.4
    • McGowan, I.1    Hoesley, C.2    Cranston, R.D.3
  • 60
    • 84890599203 scopus 로고    scopus 로고
    • The development of rectal microbicides for HIV prevention
    • McGowan I,. The development of rectal microbicides for HIV prevention. Expert Opin Drug Deliv. 2014; 11 (1): 69-82.
    • (2014) Expert Opin Drug Deliv , vol.11 , Issue.1 , pp. 69-82
    • McGowan, I.1
  • 61
    • 84873474075 scopus 로고    scopus 로고
    • Heterosexual anal intercourse: A neglected risk factor for HIV?
    • Baggaley RF, Dimitrov D, Owen BN, et al. Heterosexual anal intercourse: a neglected risk factor for HIV? Am J Reprod Immunol. 2013; 69 (Suppl 1): 95-105.
    • (2013) Am J Reprod Immunol , vol.69 , Issue.SUPPL. 1 , pp. 95-105
    • Baggaley, R.F.1    Dimitrov, D.2    Owen, B.N.3
  • 62
    • 70350335411 scopus 로고    scopus 로고
    • Higher levels of HIV-related risky behavior in polling booth surveys compared to face-to-face interviews in a general population survey in Cotonou
    • London, England:Abstract OS1.8.03
    • Minani I, Alary M, Lowndes C,. et al. Higher levels of HIV-related risky behavior in polling booth surveys compared to face-to-face interviews in a general population survey in Cotonou. 18th International Society of Sexually Transmitted Disease Research. 2009;London, England:Abstract OS1.8.03.
    • (2009) 18th International Society of Sexually Transmitted Disease Research
    • Minani, I.1    Alary, M.2    Lowndes, C.3
  • 63
    • 84880921142 scopus 로고    scopus 로고
    • Effect of computer-assisted interviewing on self-reported sexual behavior data in a microbicide clinical trial
    • Gorbach PM, Mensch BS, Husnik M, et al. Effect of computer-assisted interviewing on self-reported sexual behavior data in a microbicide clinical trial. AIDS Behav. 2013; 17 (2): 790-800.
    • (2013) AIDS Behav , vol.17 , Issue.2 , pp. 790-800
    • Gorbach, P.M.1    Mensch, B.S.2    Husnik, M.3
  • 64
    • 43449119830 scopus 로고    scopus 로고
    • Assessment of self-reported sexual behavior and condom use among female sex workers in India using a polling box approach: A preliminary report
    • Hanck SE, Blankenship KM, Irwin KS, West BS, Kershaw T,. Assessment of self-reported sexual behavior and condom use among female sex workers in India using a polling box approach: a preliminary report. Sex Transm Dis. 2008; 35 (5): 489-494.
    • (2008) Sex Transm Dis , vol.35 , Issue.5 , pp. 489-494
    • Hanck, S.E.1    Blankenship, K.M.2    Irwin, K.S.3    West, B.S.4    Kershaw, T.5
  • 65
    • 0141518673 scopus 로고    scopus 로고
    • Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial
    • Jackson JB, Musoke P, Fleming T, et al. Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial. Lancet. 2003; 362 (9387): 859-868.
    • (2003) Lancet , vol.362 , Issue.9387 , pp. 859-868
    • Jackson, J.B.1    Musoke, P.2    Fleming, T.3
  • 66
    • 79960372412 scopus 로고    scopus 로고
    • Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: Implications for HIV prevention in women
    • Karim SS, Kashuba AD, Werner L, Karim QA,. Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: implications for HIV prevention in women. Lancet. 2011; 378 (9787): 279-281.
    • (2011) Lancet , vol.378 , Issue.9787 , pp. 279-281
    • Karim, S.S.1    Kashuba, A.D.2    Werner, L.3    Karim, Q.A.4
  • 67
    • 78650549662 scopus 로고    scopus 로고
    • Preexposure chemoprophylaxis for HIV prevention in men who have sex with men
    • Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010; 363 (27): 2587-2599.
    • (2010) N Engl J Med , vol.363 , Issue.27 , pp. 2587-2599
    • Grant, R.M.1    Lama, J.R.2    Anderson, P.L.3
  • 68
    • 84879000125 scopus 로고    scopus 로고
    • Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok tenofovir study): A randomised, double-blind, placebo-controlled phase 3 trial
    • Choopanya K, Martin M, Suntharasamai P, et al. Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok tenofovir study): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2013; 381 (9883): 2083-2090.
    • (2013) Lancet , vol.381 , Issue.9883 , pp. 2083-2090
    • Choopanya, K.1    Martin, M.2    Suntharasamai, P.3
  • 69
    • 84864505868 scopus 로고    scopus 로고
    • Antiretroviral prophylaxis for HIV prevention in heterosexual men and women
    • Baeten JM, Donnell D, Ndase P, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012; 367 (5): 399-410.
    • (2012) N Engl J Med , vol.367 , Issue.5 , pp. 399-410
    • Baeten, J.M.1    Donnell, D.2    Ndase, P.3
  • 70
    • 84899788646 scopus 로고    scopus 로고
    • Effectiveness and safety of vaginal microbicide 1% tenofovir gel for prevention of HIV infection in women
    • Vienna, Austria:Abstract TUSS0204 and oral presentation
    • Karim SS, Karim QA,.Effectiveness and safety of vaginal microbicide 1% tenofovir gel for prevention of HIV infection in women. XVIII International AIDS Conference. 2010;Vienna, Austria:Abstract TUSS0204 and oral presentation.
    • (2010) XVIII International AIDS Conference
    • Karim, S.S.1    Karim, Q.A.2
  • 71
    • 84868482455 scopus 로고    scopus 로고
    • Acceptability in microbicide and PrEP trials: Current status and a reconceptualization
    • Mensch BS, van der Straten A, Katzen LL,. Acceptability in microbicide and PrEP trials: current status and a reconceptualization. Curr Opin HIV AIDS. 2012; 7 (6): 534-541.
    • (2012) Curr Opin HIV AIDS , vol.7 , Issue.6 , pp. 534-541
    • Mensch, B.S.1    Van Der Straten, A.2    Katzen, L.L.3
  • 72
    • 82755182809 scopus 로고    scopus 로고
    • Couples' acceptability of the SILCS diaphragm for microbicide delivery
    • Frezieres RG, Walsh T, Kilbourne-Brook M, Coffey PS,. Couples' acceptability of the SILCS diaphragm for microbicide delivery. Contraception. 2012; 85 (1): 99-107.
    • (2012) Contraception , vol.85 , Issue.1 , pp. 99-107
    • Frezieres, R.G.1    Walsh, T.2    Kilbourne-Brook, M.3    Coffey, P.S.4
  • 73
    • 84868477463 scopus 로고    scopus 로고
    • High acceptability of a vaginal ring intended as a microbicide delivery method for HIV prevention in African women
    • van der Straten A, Montgomery ET, Cheng H, et al. High acceptability of a vaginal ring intended as a microbicide delivery method for HIV prevention in African women. AIDS Behav. 2012; 16 (7): 1775-1786.
    • (2012) AIDS Behav , vol.16 , Issue.7 , pp. 1775-1786
    • Van Der Straten, A.1    Montgomery, E.T.2    Cheng, H.3
  • 74
    • 84859150481 scopus 로고    scopus 로고
    • Variations in microbicide gel acceptability among young women in the USA and Puerto Rico
    • Giguere R, Carballo-Dieguez A, Ventuneac A, et al. Variations in microbicide gel acceptability among young women in the USA and Puerto Rico. Cult Health Sex. 2012; 14 (2): 151-166.
    • (2012) Cult Health Sex , vol.14 , Issue.2 , pp. 151-166
    • Giguere, R.1    Carballo-Dieguez, A.2    Ventuneac, A.3
  • 75
    • 84868485927 scopus 로고    scopus 로고
    • "tell juliana": Acceptability of the candidate microbicide VivaGel(R) and two placebo gels among ethnically diverse, sexually active young women participating in a phase 1 microbicide study
    • Carballo-Dieguez A, Giguere R, Dolezal C, et al. "Tell juliana": acceptability of the candidate microbicide VivaGel(R) and two placebo gels among ethnically diverse, sexually active young women participating in a phase 1 microbicide study. AIDS Behav. 2012; 16 (7): 1761-1774.
    • (2012) AIDS Behav , vol.16 , Issue.7 , pp. 1761-1774
    • Carballo-Dieguez, A.1    Giguere, R.2    Dolezal, C.3
  • 76
    • 84899071026 scopus 로고    scopus 로고
    • Adherence challenges with drugs for pre-exposure prophylaxis to prevent HIV infection
    • Gengiah TN, Moosa A, Naidoo A, Mansoor LE,. Adherence challenges with drugs for pre-exposure prophylaxis to prevent HIV infection. Int J Clin Pharm. 2014; 36 (1): 70-85.
    • (2014) Int J Clin Pharm , vol.36 , Issue.1 , pp. 70-85
    • Gengiah, T.N.1    Moosa, A.2    Naidoo, A.3    Mansoor, L.E.4
  • 77
    • 84880192830 scopus 로고    scopus 로고
    • Adherence and acceptability in MTN 001: A randomized cross-over trial of daily oral and topical tenofovir for HIV prevention in women
    • Minnis AM, Gandham S, Richardson BA, et al. Adherence and acceptability in MTN 001: a randomized cross-over trial of daily oral and topical tenofovir for HIV prevention in women. AIDS Behav. 2013; 17 (2): 737-747.
    • (2013) AIDS Behav , vol.17 , Issue.2 , pp. 737-747
    • Minnis, A.M.1    Gandham, S.2    Richardson, B.A.3
  • 78
    • 79957678752 scopus 로고    scopus 로고
    • Acceptability of pre-exposure prophylaxis as an HIV prevention strategy: Barriers and facilitators to pre-exposure prophylaxis uptake among at-risk Peruvian populations
    • Galea JT, Kinsler JJ, Salazar X, et al. Acceptability of pre-exposure prophylaxis as an HIV prevention strategy: barriers and facilitators to pre-exposure prophylaxis uptake among at-risk Peruvian populations. Int J STD AIDS. 2011; 22 (5): 256-262.
    • (2011) Int J STD AIDS , vol.22 , Issue.5 , pp. 256-262
    • Galea, J.T.1    Kinsler, J.J.2    Salazar, X.3
  • 79
    • 84896127057 scopus 로고    scopus 로고
    • Women's experiences with oral and vaginal pre-exposure prophylaxis: The VOICE-C qualitative study in Johannesburg, South Africa
    • van der Straten A, Stadler J, Montgomery E, et al. Women's experiences with oral and vaginal pre-exposure prophylaxis: the VOICE-C qualitative study in Johannesburg, South Africa. PLoS ONE. 2014; 9 (2): e89118.
    • (2014) PLoS ONE , vol.9 , Issue.2
    • Van Der Straten, A.1    Stadler, J.2    Montgomery, E.3
  • 81
    • 84873858944 scopus 로고    scopus 로고
    • MTN-001: Randomized pharmacokinetic cross-over study comparing tenofovir vaginal gel and oral tablets in vaginal tissue and other compartments
    • Hendrix CW, Chen BA, Guddera V, et al. MTN-001: randomized pharmacokinetic cross-over study comparing tenofovir vaginal gel and oral tablets in vaginal tissue and other compartments. PLoS ONE. 2013; 8 (1): e55013.
    • (2013) PLoS ONE , vol.8 , Issue.1
    • Hendrix, C.W.1    Chen, B.A.2    Guddera, V.3
  • 82
    • 84899871303 scopus 로고    scopus 로고
    • European Medicines Agency Updated. Accessed Febuary 20, 2014
    • European Medicines Agency. Scientific discussion for the approval of viread. http://www.ema.europa.eu/docs/en-GB/document-library/EPAR-Scientific- Discussion/human/000419/WC500051732.pdf. Updated 2004. Accessed Febuary 20, 2014.
    • (2004) Scientific Discussion for the Approval of Viread
  • 83
    • 84977649754 scopus 로고    scopus 로고
    • Food US, Drug Administration Updated 2009. Accessed Febuary 20, 2014
    • Food US, Drug Administration,. Viread (tenofovir disoproxil fumarate) label update. http://www.fda.gov/ForConsumers/ByAudience/ForPatientAdvocates/ HIVandAIDSActivities/ucm125021.htm. Updated 2009. Accessed Febuary 20, 2014.
    • Viread (Tenofovir Disoproxil Fumarate) Label Update
  • 84
    • 85033050931 scopus 로고    scopus 로고
    • Nonclinical toxicology studies with zidovudine: Genetic toxicity tests and carcinogenicity bioassays in mice and rats
    • Ayers KM, Clive D, Tucker WE, Jr, Hajian G, de Miranda P,. Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats. Fundam Appl Toxicol. 1996; 32 (2): 148-158.
    • (1996) Fundam Appl Toxicol. , vol.32 , Issue.2 , pp. 148-158
    • Ayers, K.M.1    Clive, D.2    Tucker, Jr.W.E.3    Hajian, G.4    De Miranda, P.5
  • 85
    • 84881656632 scopus 로고    scopus 로고
    • A tenofovir disoproxil fumarate intravaginal ring completely protects against repeated SHIV vaginal challenge in nonhuman primates
    • Atlanta, Georgia
    • Smith J, Rastogi R, Teller R,. et al. A tenofovir disoproxil fumarate intravaginal ring completely protects against repeated SHIV vaginal challenge in nonhuman primates. 20th Conference on Retroviruses and Opportunistic Infections. 2013;Atlanta, Georgia.
    • (2013) 20th Conference on Retroviruses and Opportunistic Infections
    • Smith, J.1    Rastogi, R.2    Teller, R.3
  • 86
    • 84899801442 scopus 로고    scopus 로고
    • A novel intravaginal ring design releasing tenofovir delivers comparable tenofovir diphosphate levels in vaginal target cells in macaques to gel dosing
    • Atlanta, GA
    • Smith J, Rastogi R, Teller R,. et al. A novel intravaginal ring design releasing tenofovir delivers comparable tenofovir diphosphate levels in vaginal target cells in macaques to gel dosing. 20th Conference on Retroviruses and Opportunistic Infections. 2013;Atlanta, GA.
    • (2013) 20th Conference on Retroviruses and Opportunistic Infections
    • Smith, J.1    Rastogi, R.2    Teller, R.3
  • 89
    • 76549097076 scopus 로고    scopus 로고
    • Mucoadhesive system for vaginal delivery of the HIV microbicide, dapivirine: Optimisation by an artificial neural network
    • Woolfson AD, Umrethia ML, Kett VL, Malcolm Freeze-dried RK,. Mucoadhesive system for vaginal delivery of the HIV microbicide, dapivirine: optimisation by an artificial neural network. Int J Pharm. 2010; 388 (1-2): 136-143.
    • (2010) Int J Pharm , vol.388 , Issue.12 , pp. 136-143
    • Woolfson, A.D.1    Umrethia, M.L.2    Kett, V.L.3    Malcolm Freeze-Dried, R.K.4
  • 90
    • 84857131210 scopus 로고    scopus 로고
    • Development and characterization of a vaginal film containing dapivirine, a non- nucleoside reverse transcriptase inhibitor (NNRTI), for prevention of HIV-1 sexual transmission
    • Akil A, Parniak MA, Dezzuitti CS, et al. Development and characterization of a vaginal film containing dapivirine, a non- nucleoside reverse transcriptase inhibitor (NNRTI), for prevention of HIV-1 sexual transmission. Drug Deliv Transl Res. 2011; 1 (3): 209-222.
    • (2011) Drug Deliv Transl Res. , vol.1 , Issue.3 , pp. 209-222
    • Akil, A.1    Parniak, M.A.2    Dezzuitti, C.S.3
  • 92
    • 68049121905 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women
    • Nel A, Smythe S, Young K, et al. Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women. J Acquir Immune Defic Syndr. 2009; 51 (4): 416-423.
    • (2009) J Acquir Immune Defic Syndr , vol.51 , Issue.4 , pp. 416-423
    • Nel, A.1    Smythe, S.2    Young, K.3
  • 93
    • 66149175684 scopus 로고    scopus 로고
    • Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring
    • Romano J, Variano B, Coplan P, et al. Safety and availability of dapivirine (TMC120) delivered from an intravaginal ring. AIDS Res Hum Retroviruses. 2009; 25 (5): 483-488.
    • (2009) AIDS Res Hum Retroviruses , vol.25 , Issue.5 , pp. 483-488
    • Romano, J.1    Variano, B.2    Coplan, P.3
  • 94
    • 84890121420 scopus 로고    scopus 로고
    • Safety, acceptability and pharmacokinetic assessment (adherence) of monthly dapivirine vaginal microbicide rings (ring-004) for HIV prevention
    • Seattle, WA
    • Nel A, Kamupira M, Woodsong C,. et al. Safety, acceptability and pharmacokinetic assessment (adherence) of monthly dapivirine vaginal microbicide rings (ring-004) for HIV prevention. 19th Conference on Retrovirus and Opportunistic Infections. 2012;Seattle, WA.
    • (2012) 19th Conference on Retrovirus and Opportunistic Infections
    • Nel, A.1    Kamupira, M.2    Woodsong, C.3
  • 98
    • 84899820814 scopus 로고    scopus 로고
    • ClinicalTrials. gov Updated 2013. Accessed December 11, 2013
    • ClinicalTrials. gov. Safety and pharmacokinetics of dapirivine/maraviroc vaginal ring. http://clinicaltrials.gov/ct2/show/NCT01363037?term= NCT01363037&rank=1. Updated 2013. Accessed December 11, 2013.
    • Safety and Pharmacokinetics of Dapirivine/maraviroc Vaginal Ring
  • 99
    • 84856071435 scopus 로고    scopus 로고
    • Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring
    • Moss JA, Malone AM, Smith TJ, et al. Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring. Antimicrob Agents Chemother. 2012; 56 (2): 875-882.
    • (2012) Antimicrob Agents Chemother , vol.56 , Issue.2 , pp. 875-882
    • Moss, J.A.1    Malone, A.M.2    Smith, T.J.3
  • 101
    • 85027939499 scopus 로고    scopus 로고
    • Tenofovir diphosphate and emtricitabine triphosphate concentrations in blood cells compared with isolated peripheral blood mononuclear cells: A new measure of antiretroviral adherence?
    • Adams JL, Sykes C, Menezes P, et al. Tenofovir diphosphate and emtricitabine triphosphate concentrations in blood cells compared with isolated peripheral blood mononuclear cells: a new measure of antiretroviral adherence?. J Acquir Immune Defic Syndr. 2013; 62 (3): 260-266.
    • (2013) J Acquir Immune Defic Syndr , vol.62 , Issue.3 , pp. 260-266
    • Adams, J.L.1    Sykes, C.2    Menezes, P.3
  • 102
    • 84897452223 scopus 로고    scopus 로고
    • Strong relationship between oral dose and tenofovir hair levels in a randomized trial: Hair as a potential adherence measure for pre-exposure prophylaxis (PrEP)
    • Liu AY, Yang Q, Huang Y, et al. Strong relationship between oral dose and tenofovir hair levels in a randomized trial: hair as a potential adherence measure for pre-exposure prophylaxis (PrEP). PLoS ONE. 2014; 9 (1): e83736.
    • (2014) PLoS ONE , vol.9 , Issue.1
    • Liu, A.Y.1    Yang, Q.2    Huang, Y.3
  • 103
    • 84884667485 scopus 로고    scopus 로고
    • Safety, adherence and acceptability of intermittent tenofovir/ emtricitabine as HIV pre-exposure prophylaxis (PrEP) among HIV-uninfected Ugandan volunteers living in HIV-serodiscordant relationships: A randomized, clinical trial
    • Kibengo FM, Ruzagira E, Katende D, et al. Safety, adherence and acceptability of intermittent tenofovir/emtricitabine as HIV pre-exposure prophylaxis (PrEP) among HIV-uninfected Ugandan volunteers living in HIV-serodiscordant relationships: a randomized, clinical trial. PLoS ONE. 2013; 8 (9): e74314.
    • (2013) PLoS ONE , vol.8 , Issue.9
    • Kibengo, F.M.1    Ruzagira, E.2    Katende, D.3
  • 104
    • 84899892134 scopus 로고    scopus 로고
    • PReP adherence measurements Updated. Accessed March 5, 2014
    • Bangsberg DR,. PReP adherence measurements. Microbicide Trials Network (MTN) Web site. http://www.mtnstopshiv.org/sites/default/files/attachments/ BangsbergREVISEDMicrobicideAdherenceMonitoring3-2011.pdf. Updated 2011. Accessed March 5, 2014.
    • (2011) Microbicide Trials Network (MTN) Web Site
    • Bangsberg, D.R.1
  • 107
    • 52749091361 scopus 로고    scopus 로고
    • Safety and acceptability of coitally dependent use of 1% tenofovir over six months of use
    • New Delhi, India:Abstract No. 655
    • Hillier SL,. Safety and acceptability of coitally dependent use of 1% tenofovir over six months of use. Microbicides 2008 Conference. 2008;New Delhi, India:Abstract No. 655.
    • (2008) Microbicides 2008 Conference
    • Hillier, S.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.