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Volumn 67, Issue 9, 2012, Pages 2139-2142

Reformulated tenofovir gel for use as a dual compartment microbicide

Author keywords

Formulation; HIV prevention; Preclinical testing; Rectal microbicide; Safety

Indexed keywords

GLYCEROL; MICROBICIDE; TENOFOVIR;

EID: 84864385142     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dks173     Document Type: Article
Times cited : (70)

References (9)
  • 1
    • 77955930318 scopus 로고    scopus 로고
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    • Abdool Karim Q, Abdool Karim SS, Frohlich JA et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 2010; 329: 1168-74.
    • (2010) Science , vol.329 , pp. 1168-1174
    • Abdool Karim, Q.1    Abdool Karim, S.S.2    Frohlich, J.A.3
  • 2
    • 0033178369 scopus 로고    scopus 로고
    • Per-contact risk of human immunodeficiency virus transmission between male sexual partners
    • Vittinghoff E, Douglas J, Judson F et al. Per-contact risk of human immunodeficiency virus transmission between male sexual partners. Am J Epidemiol 1999; 150: 306-11.
    • (1999) Am J Epidemiol , vol.150 , pp. 306-311
    • Vittinghoff, E.1    Douglas, J.2    Judson, F.3
  • 3
    • 33645422725 scopus 로고    scopus 로고
    • Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women
    • Mayer KH, Maslankowski LA, Gai F et al. Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women. AIDS 2006; 20: 543-51.
    • (2006) AIDS , vol.20 , pp. 543-551
    • Mayer, K.H.1    Maslankowski, L.A.2    Gai, F.3
  • 4
    • 77949532283 scopus 로고    scopus 로고
    • In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide
    • Rohan LC, Moncla BJ, Kunjara Na Ayudhya RP et al. In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide. PLoS ONE 2010; 5: e9310.
    • (2010) PLoS ONE , vol.5
    • Rohan, L.C.1    Moncla, B.J.2    Kunjara Na Ayudhya, R.P.3
  • 5
    • 33847035951 scopus 로고    scopus 로고
    • Hyperosmolar sexual lubricant causes epithelial damage in the distal colon: potential implication for HIV transmission
    • Fuchs EJ, Lee LA, Torbenson MS et al. Hyperosmolar sexual lubricant causes epithelial damage in the distal colon: potential implication for HIV transmission. J Infect Dis 2007; 195: 703-10.
    • (2007) J Infect Dis , vol.195 , pp. 703-710
    • Fuchs, E.J.1    Lee, L.A.2    Torbenson, M.S.3
  • 6
    • 79952328020 scopus 로고    scopus 로고
    • Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations
    • Wang L, Schnaare RL, Dezzutti C et al. Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. AIDS Res Ther 2011; 8: 12.
    • (2011) AIDS Res Ther , vol.8 , pp. 12
    • Wang, L.1    Schnaare, R.L.2    Dezzutti, C.3
  • 7
    • 82555193798 scopus 로고    scopus 로고
    • The future role of rectal and vaginal microbicides to prevent HIV infection in heterosexual populations: implications for product development and prevention
    • Boily MC, Dimitrov D, Abdool Karim SS et al. The future role of rectal and vaginal microbicides to prevent HIV infection in heterosexual populations: implications for product development and prevention. Sex Transm Infect 2011; 87: 646-53.
    • (2011) Sex Transm Infect , vol.87 , pp. 646-653
    • Boily, M.C.1    Dimitrov, D.2    Abdool Karim, S.S.3
  • 8
    • 79960351190 scopus 로고    scopus 로고
    • RMP-02/MTN-006: a Phase 1 placebo-controlled trial of rectally applied 1% vaginal TFV gel with comparison to oral TDF
    • Abstract #Y-1025. Foundation for Retrovirology and Human Health, Alexandria, VA, USA
    • Anton P, Cranston R, Carballo-Dieguez A et al. RMP-02/MTN-006: a Phase 1 placebo-controlled trial of rectally applied 1% vaginal TFV gel with comparison to oral TDF. In: Abstracts of the Eighteenth Conference on Retroviruses and Opportunistic Infections, Boston, MA, 2011. Abstract #Y-1025. Foundation for Retrovirology and Human Health, Alexandria, VA, USA.
    • Abstracts of the Eighteenth Conference on Retroviruses and Opportunistic Infections, Boston, MA, 2011
    • Anton, P.1    Cranston, R.2    Carballo-Dieguez, A.3
  • 9
    • 80053248640 scopus 로고    scopus 로고
    • First Phase 1 double-blind, placebo-controlled, randomized rectal microbicide trial using UC781 gel with a novel index of ex vivo efficacy
    • Anton PA, Saunders T, Elliott J et al. First Phase 1 double-blind, placebo-controlled, randomized rectal microbicide trial using UC781 gel with a novel index of ex vivo efficacy. PLoS ONE 2011; 6: e23243.
    • (2011) PLoS ONE , vol.6
    • Anton, P.A.1    Saunders, T.2    Elliott, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.