Freeze-dried, mucoadhesive system for vaginal delivery of the HIV microbicide, dapivirine: Optimisation by an artificial neural network

International Journal of Pharmaceutics

Volumn 388, Issue 1-2, 2010, Pages 136-143

  Woolfson, A David ^a   Umrethia, Manish L ^a   Kett, Victoria L ^a   Malcolm, R Karl ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Artificial neural network; Dapivirine; Freeze drying; HIV AIDS; Microbicides; Vaginal drug delivery

Indexed keywords

DAPIVIRINE; HYDROXYPROPYLMETHYLCELLULOSE; POVIDONE;

ARTICLE; ARTIFICIAL NEURAL NETWORK; CONTROLLED STUDY; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; FACTORIAL DESIGN; FREEZE DRYING; GEL; IN VITRO STUDY; MEAN RESIDENCE TIME; MUCOADHESION; MUCOADHESIVE TABLET; PRIORITY JOURNAL; PROCESS OPTIMIZATION; TABLET; TABLET MANUFACTURE; VAGINA; VISCOSITY;

ADHESIVENESS; ADMINISTRATION, INTRAVAGINAL; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; FREEZE DRYING; GELS; METHYLCELLULOSE; NEURAL NETWORKS (COMPUTER); POVIDONE; PYRIMIDINES; REVERSE TRANSCRIPTASE INHIBITORS; TABLETS;

EID: 76549097076     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.12.042     Document Type: Article

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