Exploration of sequence space as the basis of viral RNA genome segmentation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 18, 2014, Pages 6678-6683

  Moreno, Elena ^a   Ojosnegros, Samuel ^a,c   García Arriaza, Juan ^c,d   Escarmís, Cristina ^a   Domingo, Esteban ^a,b   Perales, Celia ^a,b  

^a CSIC   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^d CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

Evolutionary transition; Mutant spectrum; Quasi species; RNA virus evolution; Viral emergence

Indexed keywords

PROTEINASE; PROTEINASE L; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

ANIMAL CELL; ARTICLE; BHK CELL LINE; FITNESS; GENE DELETION; GENE STRUCTURE; GENETIC DRIFT; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; RNA VIRUS; SEQUENCE ANALYSIS; VIRUS GENOME; VIRUS STRAIN;

EVOLUTIONARY TRANSITION; MUTANT SPECTRUM; QUASI-SPECIES; RNA VIRUS EVOLUTION; VIRAL EMERGENCE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; CELL LINE; CRICETINAE; ENDOPEPTIDASES; EVOLUTION, MOLECULAR; FOOT-AND-MOUTH DISEASE VIRUS; GENETIC COMPLEMENTATION TEST; GENETIC DRIFT; GENOME, VIRAL; MOLECULAR SEQUENCE DATA; POINT MUTATION; RNA, VIRAL; SELECTION, GENETIC; SEQUENCE DELETION; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84899792193     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1323136111     Document Type: Article

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