Permeation redux: Thermodynamics and kinetics of ion movement through potassium channels

Biophysical Journal

Volumn 106, Issue 9, 2014, Pages 1859-1863

  Horn, Richard ^a   Roux, Benoît ^b   Åqvist, Johan ^c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ION; POTASSIUM CHANNEL;

CHEMISTRY; KINETICS; METABOLISM; MOVEMENT (PHYSIOLOGY); PERMEABILITY; THERMODYNAMICS;

IONS; KINETICS; MOVEMENT; PERMEABILITY; POTASSIUM CHANNELS; THERMODYNAMICS;

EID: 84899784442     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2014.03.039     Document Type: Review

References (43)

1. F. Bezanilla, and C.M. Armstrong Negative conductance caused by entry of sodium and cesium ions into the K channels of squid axon J. Gen. Physiol. 53 1972 342 347
2. Eisenman, G.; and S. Krasne. 1973. Further considerations on the ion selectivity of carrier molecules and membranes. In IV International Biophysics Congress Symposium on Membrane Structure and Function, Moscow, Russia.
3. + channel J. Gen. Physiol. 92 1988 569 586
4. K.N. Piasta, D.L. Theobald, and C. Miller Potassium-selective block of barium permeation through single KcsA channels J. Gen. Physiol. 138 2011 421 436
5. G. Eisenman Cation selective glass electrodes and their mode of operation Biophys. J. 2 1962 259 323
6. G. Eisenman On the Elementary Atomic Origin of Equilibrium Ionic Specificity 1961 Academic Press New York
7. G. Eisenman, and R. Horn Ionic selectivity revisited: the role of kinetic and equilibrium processes in ion permeation through channels J. Membr. Biol. 76 1983 197 225
8. J.M. Diamond, and E.M. Wright Biological membranes: the physical basis of ion and nonelectrolyte selectivity Annu. Rev. Physiol. 31 1969 581 646
9. E.M. Wright, and J.M. Diamond Anion selectivity in biological systems Physiol. Rev. 57 1977 109 156
10. J.A. McCammon, B.R. Gelin, and M. Karplus Dynamics of folded proteins Nature 267 1977 585 590
11. T.W. Allen, O.S. Andersen, and B. Roux Energetics of ion conduction through the gramicidin channel Proc. Natl. Acad. Sci. USA 101 2004 117 122
12. J. Aqvist, O. Alvarez, and G. Eisenman Ion-selective properties of a small ionophore in methanol studied by free energy perturbation simulations J. Phys. Chem. 96 1992 10019 10025
13. G. Eisenman, and O. Alvarez Structure and function of channels and channelogs as studied by computational chemistry J. Membr. Biol. 119 1991 109 132
14. + conduction and selectivity Science 280 1998 69 77
15. G. Eisenman, J. Aqvist, and O. Alvarez Free-energies underlying ion binding and transport in protein channels - free-energy perturbation simulations of ion binding and selectivity for valinomycin J. Chem. Soc.; Faraday Trans. 87 1991 2099 2109
16. 3+ luminescence spectroscopy: a marked size-selectivity among rare earth ions Biophys. Chem. 42 1992 249 256
17. + selectivity of the KcsA potassium channel from microscopic free energy perturbation calculations Biochim. Biophys. Acta 1548 2001 194 202
18. + binding sites with two different mechanisms J. Mol. Biol. 377 2008 804 818
19. +-selectivity of the Na/K pump Nat. Struct. Mol. Biol. 18 2011 1159 1163
20. B.I. Zwolinski, H. Eyring, and C.E. Resese Diffusion and membrane permeability J. Phys. Colloid Chem. 53 1949 1426 1453
21. B. Hille Ionic selectivity, saturation, and block in sodium channels. A four-barrier model J. Gen. Physiol. 66 1975 535 560
22. + channel Nature 414 2001 73 77
23. P. Läuger, W. Stephan, and E. Frehland Fluctuations of barrier structure in ionic channels Biochim. Biophys. Acta 602 1980 167 180
24. B. Roux Perspectives on: molecular dynamics and computational methods J. Gen. Physiol. 135 2010 547 548
25. R.O. Dror, and M.O. Jensen D.E. Shaw Exploring atomic resolution physiology on a femtosecond to millisecond timescale using molecular dynamics simulations J. Gen. Physiol. 135 2010 555 562
26. B. Eisenberg Interacting ions in biophysics: real is not ideal Biophys. J. 104 2013 1849 1866
27. + conduction in selective and nonselective ion channels via molecular dynamics simulations Biophys. J. 105 2013 1737 1745
28. + channel Biochemistry 38 1999 8599 8604
29. I.H. Shrivastava, and M.S. Sansom Simulations of ion permeation through a potassium channel: molecular dynamics of KcsA in a phospholipid bilayer Biophys. J. 78 2000 557 570
30. T.W. Allen, S. Kuyucak, and S.H. Chung Molecular dynamics study of the KcsA potassium channel Biophys. J. 77 1999 2502 2516
31. J. Åqvist, and V.B. Luzhkov Ion permeation mechanism of the potassium channel Nature 404 2000 881 884
32. S.Y. Noskov, S. Bernèche, and B. Roux Control of ion selectivity in potassium channels by electrostatic and dynamic properties of carbonyl ligands Nature 431 2004 830 834
33. + channel pore Nat. Struct. Mol. Biol. 17 2010 1019 1023
34. M.G. Derebe, and D.B. Sauer Y. Jiang Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites Proc. Natl. Acad. Sci. USA 108 2011 598 602
35. + channels Nat. Commun 4 2013 2746
36. D.B. Sauer, and W. Zeng Y. Jiang Sodium and potassium competition in potassium-selective and non-selective channels Nat. Commun 4 2013 2721
37. + cations J. Am. Chem. Soc. 107 1985 5504 5513
38. D.H. Mackay, and P.H. Berens A.T. Hagler Structure and dynamics of ion transport through gramicidin A Biophys. J. 46 1984 229 248
39. + by gramicidin A Biophys. J. 56 1989 171 182
40. B. Roux, and M. Karplus Ion-transport in the gramicidin channel - free-energy of the solvated right-handed dimer in a model membrane J. Am. Chem. Soc. 115 1993 3250 3262
41. +. Influence of the flexibility of the ethanolamine end chain on the profiles FEBS Lett. 173 1984 301 306
42. G. Eisenman, and J.P. Sandblom Modeling the gramicidin channel: interpretation of experimental data using rate theory Biophys. J. 45 1984 88 90
43. M.O. Jensen, and V. Jogini D.E. Shaw Atomic-level simulation of current-voltage relationships in single-file ion channels J. Gen. Physiol. 141 2013 619 632