메뉴 건너뛰기




Volumn 41, Issue 5, 2014, Pages 945-954

Aggrecanases, and RANKL expression are partially prevented by hyaluronic acid in interleukin 1-stimulated osteoblasts

Author keywords

Adamts Tissue Inhibitor Of Metalloproteinases; Hyaluronic Acid; Metalloproteinases; Osteoblasts; Rank Ligand

Indexed keywords

AGGRECANASE; AGGRECANASE 1; AGGRECANASE 2; COLLAGENASE 3; HERMES ANTIGEN; HYALURONIC ACID; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; ADAM PROTEIN; ADAMTS5 PROTEIN, MOUSE; AGGRECANASE-1; MESSENGER RNA; MMP13 PROTEIN, MOUSE; MMP3 PROTEIN, MOUSE; PROCOLLAGEN N PROTEINASE; PROTEINASE; TNFSF11 PROTEIN, MOUSE; VISCOSUPPLEMENT;

EID: 84899750841     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.130378     Document Type: Article
Times cited : (31)

References (50)
  • 1
    • 79959341732 scopus 로고    scopus 로고
    • Osteoarthritis: An update with relevance for clinical practice
    • Bijlsma J, Berenbaum F, Lafeber F. Osteoarthritis: an update with relevance for clinical practice. Lancet 2011;377:2115-26
    • (2011) Lancet , vol.377 , pp. 2115-2126
    • Bijlsma, J.1    Berenbaum, F.2    Lafeber, F.3
  • 2
    • 78650975710 scopus 로고    scopus 로고
    • The bone-cartilage unit in osteoarthritis
    • Lories RJ, Luyten FP. The bone-cartilage unit in osteoarthritis. Nat Rev Rheumatol 2010;7:43-9
    • (2010) Nat Rev Rheumatol , vol.7 , pp. 43-49
    • Lories, R.J.1    Luyten, F.P.2
  • 3
    • 64849086188 scopus 로고    scopus 로고
    • ADAMTS5-/- mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: Implications for a link between cartilage and subchondral bone changes
    • Botter SM, Glasson SS, Hopkins B, Clockaerts S, Weinans H, van Leeuwen JPTM, et al. ADAMTS5-/- mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage and subchondral bone changes. Osteoarthritis Cartilage 2009;17:636-45
    • (2009) Osteoarthritis Cartilage , vol.17 , pp. 636-645
    • Botter, S.M.1    Glasson, S.S.2    Hopkins, B.3    Clockaerts, S.4    Weinans, H.5    Van Leeuwen, J.P.T.M.6
  • 4
    • 49449084869 scopus 로고    scopus 로고
    • Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis
    • Kadri A, Ea K, Bazille C, Hannouche D, Lioté F, Cohen-Solal ME. Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis. Arthritis Rheum 2008;58:2379-86
    • (2008) Arthritis Rheum , vol.58 , pp. 2379-2386
    • Kadri, A.1    Ea, K.2    Bazille, C.3    Hannouche, D.4    Lioté, F.5    Cohen-Solal, M.E.6
  • 5
    • 1842632402 scopus 로고    scopus 로고
    • The role of subchondral bone remodeling in osteoarthritis: Reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model
    • DOI 10.1002/art.20124
    • Hayami T, Pickarski M, Wesolowski GA, McLane J, Bone A, Destefano J, et al. The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. Arthritis Rheum 2004;50:1193-206 (Pubitemid 38480830)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.4 , pp. 1193-1206
    • Hayami, T.1    Pickarski, M.2    Wesolowski, G.A.3    McLane, J.4    Bone, A.5    Destefano, J.6    Rodan, G.A.7    Duong, L.T.8
  • 6
    • 0031738172 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinases (MMP-2, -3, -9, and -13) by interleukin-1 and interleukin-6 in mouse calvaria: Association of MMP induction with bone resorption
    • Kusano K, Miyaura C, Inada M, Tamura T, Ito A, Nagase H, et al. Regulation of matrix metalloproteinases (MMP-2, -3, -9, and -13) by interleukin-1 and interleukin-6 in mouse calvaria: association of MMP induction with bone resorption. Endocrinology 2008;139:1338-45
    • (2008) Endocrinology , vol.139 , pp. 1338-1345
    • Kusano, K.1    Miyaura, C.2    Inada, M.3    Tamura, T.4    Ito, A.5    Nagase, H.6
  • 7
    • 61549087822 scopus 로고    scopus 로고
    • Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts
    • Sanchez C, Gabay O, Salvat C, Henrotin YE, Berenbaum F. Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts. Osteoarthritis Cartilage 2009;17:473-81
    • (2009) Osteoarthritis Cartilage , vol.17 , pp. 473-481
    • Sanchez, C.1    Gabay, O.2    Salvat, C.3    Henrotin, Y.E.4    Berenbaum, F.5
  • 8
    • 0035174308 scopus 로고    scopus 로고
    • Articular cartilage and changes in arthritis matrix degradation
    • DOI 10.1186/ar325
    • Mort JS, Billington CJ. Articular cartilage and changes in arthritis: matrix degradation. Arthritis Res 2001;3:337-41 (Pubitemid 33077113)
    • (2001) Arthritis Research , vol.3 , Issue.6 , pp. 337-341
    • Mort, J.S.1    Billington, C.J.2
  • 9
    • 84879246367 scopus 로고    scopus 로고
    • Aggrecanases in the human synovial fluid at different stages of osteoarthritis
    • Zhang E, Yan X, Zhang M, Chang X, Bai Z, He Y, et al. Aggrecanases in the human synovial fluid at different stages of osteoarthritis. Clin Rheumatol 2013;32:797-803
    • (2013) Clin Rheumatol , vol.32 , pp. 797-803
    • Zhang, E.1    Yan, X.2    Zhang, M.3    Chang, X.4    Bai, Z.5    He, Y.6
  • 11
    • 0029766216 scopus 로고    scopus 로고
    • Metalloproteinase inhibitors and the prevention of connective tissue breakdown
    • DOI 10.1016/0163-7258(96)00015-0
    • Cawston TE. Metalloproteinase inhibitors and the prevention of connective tissue breakdown. Pharmacol Ther 1996;70:163-82 (Pubitemid 26259574)
    • (1996) Pharmacology and Therapeutics , vol.70 , Issue.3 , pp. 163-182
    • Cawston, T.E.1
  • 13
    • 2542436756 scopus 로고    scopus 로고
    • Matrix metalloproteinases and their endogenous inhibitors in neuronal physiology of the adult brain
    • DOI 10.1016/j.febslet.2004.03.070, PII S0014579304003746
    • Dzwonek J, Rylski M, Kaczmarek L. Matrix metalloproteinases and their endogenous inhibitors in neuronal physiology of the adult brain. FEBS Letters 2004;567:129-35 (Pubitemid 38686435)
    • (2004) FEBS Letters , vol.567 , Issue.1 , pp. 129-135
    • Dzwonek, J.1    Rylski, M.2    Kaczmarek, L.3
  • 15
    • 34250212488 scopus 로고    scopus 로고
    • Angiogenesis in the synovium and at the osteochondral junction in osteoarthritis
    • DOI 10.1016/j.joca.2007.01.020, PII S1063458407000581
    • Walsh DA, Bonnet CS, Turner EL, Wilson D, Situ M, McWilliams DF. Angiogenesis in the synovium and at the osteochondral junction in osteoarthritis. Osteoarthritis Cartil 2007;15:743-51 (Pubitemid 46893968)
    • (2007) Osteoarthritis and Cartilage , vol.15 , Issue.7 , pp. 743-751
    • Walsh, D.A.1    Bonnet, C.S.2    Turner, E.L.3    Wilson, D.4    Situ, M.5    McWilliams, D.F.6
  • 16
    • 22644445151 scopus 로고    scopus 로고
    • The role of subchondral bone resorption pits in osteoarthritis: MMP production by cells derived from bone marrow
    • DOI 10.1016/j.joca.2005.04.010, PII S1063458405001068
    • Shibakawa A, Yudoh K, Masuko-Hongo K, Kato T, Nishioka K, Nakamura H. The role of subchondral bone resorption pits in osteoarthritis: MMP production by cells derived from bone marrow. Osteoarthritis Cartilage 2005;13:679-87 (Pubitemid 41025121)
    • (2005) Osteoarthritis and Cartilage , vol.13 , Issue.8 , pp. 679-687
    • Shibakawa, A.1    Yudoh, K.2    Masuko-Hongo, K.3    Kato, T.4    Nishioka, K.5    Nakamura, H.6
  • 17
    • 0018866768 scopus 로고
    • A study of the arterial supply of the patella in the normal state, in chondromalacia patellae and in osteoarthrosis
    • Bjorkstrom S, Goldie IF. A study of the arterial supply of the patella in the normal state, in chondromalacia patellae and in osteoarthrosis. Acta Orthop Scand 1980;51:63-70 (Pubitemid 10173819)
    • (1980) Acta Orthopaedica Scandinavica , vol.51 , Issue.1 , pp. 63-70
    • Bjorkstrom, S.1    Goldie, I.F.2
  • 18
    • 0017621756 scopus 로고
    • The vascularity and remodelling of subchondral bone and calcified cartilage in adult human femoral and humeral heads. An age and stress related phenomenon
    • Lane LB, Villacin A, Bullough PG. The vascularity and remodelling of subchondrial bone and calcified cartilage in adult human femoral and humeral heads. An age- and stress-related phenomenon. J Bone Joint Surg Br 1977;59:272-8 (Pubitemid 8168937)
    • (1977) Journal of Bone and Joint Surgery - Series B , vol.59 , Issue.3 , pp. 272-278
    • Lane, L.B.1    Villacin, A.2    Bullough, P.G.3
  • 20
    • 43349095508 scopus 로고    scopus 로고
    • The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kappab ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells
    • Kwan Tat S, Pelletier JP, Lajeunesse D, Fahmi H, Lavigne M, Martel-Pelletier J. The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kappaB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells. Clin Exp Rheumatol 2008;26:295-304 (Pubitemid 351659137)
    • (2008) Clinical and Experimental Rheumatology , vol.26 , Issue.2 , pp. 295-304
    • Kwan Tat, S.1    Pelletier, J.-P.2    Lajeunesse, D.3    Fahmi, H.4    Lavigne, M.5    Martel-Pelletier, J.6
  • 21
    • 9244252016 scopus 로고    scopus 로고
    • The molecular triad OPG/RANK/RANKL: Involvement in the orchestration of pathophysiological bone remodeling
    • DOI 10.1016/j.cytogfr.2004.06.004, PII S1359610104000747
    • Theoleyre S, Wittrant Y, Tak SK, Fortun Y, Redini F, Heymann D. The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling. Cytokine Growth Factor Rev 2004;15:457-75 (Pubitemid 39550455)
    • (2004) Cytokine and Growth Factor Reviews , vol.15 , Issue.6 , pp. 457-475
    • Theoleyre, S.1    Wittrant, Y.2    Tat, S.K.3    Fortun, Y.4    Redini, F.5    Heymann, D.6
  • 23
    • 78649906037 scopus 로고    scopus 로고
    • High molecular weight hyaluronic acid inhibits IL-6-induced MMP production from human chondrocytes by up-regulating the ERK inhibitor, MKP-1
    • Hashizume M, Mihara M. High molecular weight hyaluronic acid inhibits IL-6-induced MMP production from human chondrocytes by up-regulating the ERK inhibitor, MKP-1. Biochem Biophys Res Commun 2010;403:184-9
    • (2010) Biochem Biophys Res Commun , vol.403 , pp. 184-189
    • Hashizume, M.1    Mihara, M.2
  • 24
    • 0043065379 scopus 로고    scopus 로고
    • A one-year, randomised, placebo (saline) controlled clinical trial of 500-730 KDA sodium hyaluronate (hyalgan) on the radiological change in osteoarthritis of the knee
    • Jubb RW, Piva S, Beinat L, Dacre J, Gishen P. A one-year, randomised, placebo (saline) controlled clinical trial of 500-730kDa sodium hyaluronate (Hyalgan) on the radiological change in osteoarthritis of the knee. Int J Clin Pract 2003; 57:467-74 (Pubitemid 36974884)
    • (2003) International Journal of Clinical Practice , vol.57 , Issue.6 , pp. 467-474
    • Jubb, R.W.1    Piva, S.2    Beinat, L.3    Dacre, J.4    Gishen, P.5
  • 25
    • 0031004381 scopus 로고    scopus 로고
    • Arthroscopic evaluation of potential structure modifying activity of hyaluronan (Hyalgan) in osteoarthritis of the knee
    • DOI 10.1016/S1063-4584(97)80010-6
    • Listrat V, Ayral X, Patarnello F, Bonvarlet JP, Simonnet J, Amor B, et al. Arthroscopic evaluation of potential structure modifying activity of hyaluronan (Hyalgan) in osteoarthritis of the knee. Osteoarthritis Cartilage 1997;5:153-60 (Pubitemid 27261990)
    • (1997) Osteoarthritis and Cartilage , vol.5 , Issue.3 , pp. 153-160
    • Listrat, V.1    Ayral, X.2    Patarnello, F.3    Bonvarlet, J.-P.4    Simonnet, J.5    Amor, B.6    Dougados, M.7
  • 26
    • 1042290333 scopus 로고    scopus 로고
    • Inhibition of Interleukin-1beta-Stimulated Production of Matrix Metalloproteinases by Hyaluronan via CD44 in Human Articular Cartilage
    • DOI 10.1002/art.20004
    • Julovi SM, Yasuda T, Shimizu M, Hiramitsu T, Nakamura T. Inhibition of interleukin-1beta-stimulated production of matrix metalloproteinases by hyaluronan via CD44 in human articular cartilage. Arthritis Rheum 2004;50:516-25 (Pubitemid 38198835)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.2 , pp. 516-525
    • Julovi, S.M.1    Yasuda, T.2    Shimizu, M.3    Hiramitsu, T.4    Nakamura, T.5
  • 27
    • 79251549199 scopus 로고    scopus 로고
    • Intra-articular injection of hyaluronan restores the aberrant expression of matrix metalloproteinase-13 in osteoarthritic subchondral bone
    • Hiraoka N, Takahashi KA, Arai Y, Sakao K, Mazda O, Kishida T, et al. Intra-articular injection of hyaluronan restores the aberrant expression of matrix metalloproteinase-13 in osteoarthritic subchondral bone. J Orthop Res 2011;29:354-60
    • (2011) J Orthop Res , vol.29 , pp. 354-360
    • Hiraoka, N.1    Takahashi, K.A.2    Arai, Y.3    Sakao, K.4    Mazda, O.5    Kishida, T.6
  • 28
    • 61549087822 scopus 로고    scopus 로고
    • Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts
    • Sanchez C, Gabay O, Salvat C, Henrotin YE, Berenbaum F. Mechanical loading highly increases IL-6 production and decreases OPG expression by osteoblasts. Osteoarthritis Cartilage 2009;17:473-81
    • (2009) Osteoarthritis Cartilage , vol.17 , pp. 473-481
    • Sanchez, C.1    Gabay, O.2    Salvat, C.3    Henrotin, Y.E.4    Berenbaum, F.5
  • 29
    • 4344586823 scopus 로고    scopus 로고
    • Up-regulation of microsomal prostaglandin e synthase 1 in osteoarthritic human cartilage: Critical roles of the ERK-1/2 and p38 signaling pathways
    • DOI 10.1002/art.20437
    • Masuko-Hongo K, Berenbaum F, Humbert L, Salvat C, Goldring MB, Thirion S. Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways. Arthritis Rheum 2004;50:2829-38 (Pubitemid 39209520)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.9 , pp. 2829-2838
    • Masuko-Hongo, K.1    Berenbaum, F.2    Humbert, L.3    Salvat, C.4    Goldring, M.B.5    Thirion, S.6
  • 30
    • 0024460791 scopus 로고
    • Urinary hydroxy-pyridinium crosslinks provide indices of cartilage and bone involvement in arthritic diseases
    • Seibel MJ, Duncan A, Robins SP. Urinary hydroxy-pyridinium crosslinks provide indices of cartilage and bone involvement in arthritic diseases. J Rheumatol 1989;16:964-70 (Pubitemid 19220212)
    • (1989) Journal of Rheumatology , vol.16 , Issue.7 , pp. 964-970
    • Seibel, M.I.1    Duncan, A.2    Robins, S.P.3
  • 31
    • 0026059490 scopus 로고
    • Progression of osteoarthritis of the hand and metacarpal bone loss. A twenty-year followup of incident cases
    • Sowers M, Zobel D, Weissfeld L, Hawthorne VM, Carman W. Progression of osteoarthritis of the hand and metacarpal bone loss. A twenty-year followup of incident cases. Arthritis Rheum 1991;34:36-42
    • (1991) Arthritis Rheum , vol.34 , pp. 36-42
    • Sowers, M.1    Zobel, D.2    Weissfeld, L.3    Hawthorne, V.M.4    Carman, W.5
  • 32
    • 0032772737 scopus 로고    scopus 로고
    • The electron microscope appearance of the subchondral bone plate in the human femoral head in osteoarthritis and osteoporosis
    • DOI 10.1017/S0021878299005099
    • Li B, Marshall D, Roe M, Aspden RM. The electron microscope appearance of the subchondral bone plate in the human femoral head in osteoarthritis and osteoporosis. J Anat 1999;195:101-10 (Pubitemid 29378199)
    • (1999) Journal of Anatomy , vol.195 , Issue.1 , pp. 101-110
    • Li, B.1    Marshall, D.2    Roe, M.3    Aspden, R.M.4
  • 33
    • 49149110090 scopus 로고    scopus 로고
    • Differences in matrix composition between calvaria and long bone in mice suggest differences in biomechanical properties and resorption: Special emphasis on collagen
    • Van den Bos T, Speijer D, Bank RA, Brömme D, Everts V. Differences in matrix composition between calvaria and long bone in mice suggest differences in biomechanical properties and resorption: special emphasis on collagen. Bone 2008;43:459-68
    • (2008) Bone , vol.43 , pp. 459-468
    • Van Den Bos, T.1    Speijer, D.2    Bank, R.A.3    Brömme, D.4    Everts, V.5
  • 34
    • 84855858086 scopus 로고    scopus 로고
    • Structural differences in the osteocyte network between the calvaria and long bone revealed by three-dimensional fluorescence morphometry, possibly reflecting distinct mechano-adaptations and sensitivities
    • Himeno-Ando A, Izumi Y, Yamaguchi A, Iimura T. Structural differences in the osteocyte network between the calvaria and long bone revealed by three-dimensional fluorescence morphometry, possibly reflecting distinct mechano-adaptations and sensitivities. Biochem Biophys Res Commun 2012;417:765-70
    • (2012) Biochem Biophys Res Commun , vol.417 , pp. 765-770
    • Himeno-Ando, A.1    Izumi, Y.2    Yamaguchi, A.3    Iimura, T.4
  • 35
    • 0035128463 scopus 로고    scopus 로고
    • Different responsiveness of cells from adult and neonatal mouse bone to mechanical and biochemical challenge
    • DOI 10.1002/1097-4652(2000) 9999:999<000::AID-JCP1041>3.0.CO;2-B
    • Soejima K, Klein-Nulend J, Semeins CM, Burger EH. Different responsiveness of cells from adult and neonatal mouse bone to mechanical and biochemical challenge. J Cell Physiol 2001;186:366-70 (Pubitemid 32147719)
    • (2001) Journal of Cellular Physiology , vol.186 , Issue.3 , pp. 366-370
    • Soejima, K.1    Klein-Nulend, J.2    Semeins, C.M.3    Burger, E.H.4
  • 38
    • 34548414633 scopus 로고    scopus 로고
    • Rheological properties of synovial fluids
    • Fam H, Bryant JT, Kontopoulou M. Rheological properties of synovial fluids. Biorheology 2007;44:59-74 (Pubitemid 47356403)
    • (2007) Biorheology , vol.44 , Issue.2 , pp. 59-74
    • Fam, H.1    Bryant, J.T.2    Kontopoulou, M.3
  • 39
    • 0036671094 scopus 로고    scopus 로고
    • Potential mechanism of action of intra-articular hyaluronan therapy in osteoarthritis: Are the effects molecular weight dependent?
    • DOI 10.1053/sarh.2002.33720
    • Ghosh P, Guidolin D. Potential mechanism of action of intraarticular hyaluronan therapy in osteoarthritis: are the effects molecular weight dependent? Semin Arthritis Rheum 2002; 32:10-37 (Pubitemid 35001162)
    • (2002) Seminars in Arthritis and Rheumatism , vol.32 , Issue.1 , pp. 10-37
    • Ghosh, P.1    Guidolin, D.2
  • 42
    • 59649094578 scopus 로고    scopus 로고
    • Aggrecanase and aggrecan degradation in osteoarthritis: A review
    • Huang K, Wu LD. Aggrecanase and aggrecan degradation in osteoarthritis: A review. J Int Med Res 2008;36:1149-60
    • (2008) J Int Med Res , vol.36 , pp. 1149-1160
    • Huang, K.1    Wu, L.D.2
  • 43
    • 0034956272 scopus 로고    scopus 로고
    • The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis
    • John A, Tuszynski G. The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis. Pathol Oncol Res 2001;7:14-23 (Pubitemid 32591662)
    • (2001) Pathology Oncology Research , vol.7 , Issue.1 , pp. 14-23
    • John, A.1    Tuszynski, G.2
  • 44
    • 0030669224 scopus 로고    scopus 로고
    • Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2
    • Olson MW, Gervasi DC, Mobashery S, Fridman R. Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2. J Biol Chem 1997;272:29975-83
    • (1997) J Biol Chem , vol.272 , pp. 29975-29983
    • Olson, M.W.1    Gervasi, D.C.2    Mobashery, S.3    Fridman, R.4
  • 45
    • 0034613296 scopus 로고    scopus 로고
    • TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix
    • Yu WH, Yu S, Meng Q, Brew K, Woessner JF Jr. TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix. J Biol Chem 2000;275:31226-32
    • (2000) J Biol Chem , vol.275 , pp. 31226-31232
    • Yu, W.H.1    Yu, S.2    Meng, Q.3    Brew, K.4    Woessner Jr., J.F.5
  • 46
    • 0036217851 scopus 로고    scopus 로고
    • Tissue inhibitor of metalloproteinases-4 (TIMP-4) gene expression is increased in human osteoarthritic femoral head cartilage
    • DOI 10.1002/jcb.10138
    • Huang W, Li WQ, Dehnade F, Zafarullah M. Tissue inhibitor of metalloproteinases-4 (TIMP-4) gene expression is increased in human osteoarthritic femoral head cartilage. J Cell Biochem 2002;85:295-303 (Pubitemid 34274897)
    • (2002) Journal of Cellular Biochemistry , vol.85 , Issue.2 , pp. 295-303
    • Huang, W.1    Li, W.Q.2    Dehnade, F.3    Zafarullah, M.4
  • 47
    • 65949100790 scopus 로고    scopus 로고
    • New perspective in osteoarthritis: The OPG and RANKL system as a potential therapeutic target?
    • Tat SK, Pelletier JP, Velasco CR, Padrines M, Martel-Pelletier J. New perspective in osteoarthritis: the OPG and RANKL system as a potential therapeutic target? Keio J Med 2009;58:29-40
    • (2009) Keio J Med , vol.58 , pp. 29-40
    • Tat, S.K.1    Pelletier, J.P.2    Velasco, C.R.3    Padrines, M.4    Martel-Pelletier, J.5
  • 48
    • 33745612740 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1 mediates the inhibitory effects of hyaluronan on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts via down-regulation of NF-kappaB and p38
    • DOI 10.1093/rheumatology/kel026
    • Hiramitsu T, Yasuda T, Ito H, Shimizu M, Julovi SM, Kakinuma T, et al. Intercellular adhesion molecule-1 mediates the inhibitory effects of hyaluronan on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts via down-regulation of NF-kappaB and p38. Rheumatology 2006;45:824-32 (Pubitemid 43985370)
    • (2006) Rheumatology , vol.45 , Issue.7 , pp. 824-832
    • Hiramitsu, T.1    Yasuda, T.2    Ito, H.3    Shimizu, M.4    Julovi, S.M.5    Kakinuma, T.6    Akiyoshi, M.7    Yoshida, M.8    Nakamura, T.9
  • 49
    • 1042290333 scopus 로고    scopus 로고
    • Inhibition of Interleukin-1beta-Stimulated Production of Matrix Metalloproteinases by Hyaluronan via CD44 in Human Articular Cartilage
    • DOI 10.1002/art.20004
    • Julovi SM, Yasuda T, Shimizu M, Hiramitsu T, Nakamura T. Inhibition of interleukin-1beta-stimulated production of matrix metalloproteinases by hyaluronan via CD44 in human articular cartilage. Arthritis Rheum 2004;50:516-25 (Pubitemid 38198835)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.2 , pp. 516-525
    • Julovi, S.M.1    Yasuda, T.2    Shimizu, M.3    Hiramitsu, T.4    Nakamura, T.5
  • 50
    • 2542480918 scopus 로고
    • A study on viscosity of normal and pathological human synovial fluid
    • Kondo H. A study on viscosity of normal and pathological human synovial fluid. Kitasato Med 1980;10:485-98.
    • (1980) Kitasato Med , vol.10 , pp. 485-498
    • Kondo, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.