메뉴 건너뛰기




Volumn 15, Issue 5, 2014, Pages

Hypoxic-ischemic brain injury: Potential therapeutic interventions for the future

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84899742138     PISSN: 15269906     EISSN: 15269906     Source Type: Journal    
DOI: 10.1542/neo.15-5-e177     Document Type: Article
Times cited : (21)

References (85)
  • 1
    • 7444267966 scopus 로고    scopus 로고
    • Neonatal brain injury
    • Ferriero DM. Neonatal brain injury. N Engl J Med. 2004;351 (19):1985-1995
    • (2004) N Engl J Med. , vol.351 , Issue.19 , pp. 1985-1995
    • Ferriero, D.M.1
  • 2
    • 26444452073 scopus 로고    scopus 로고
    • Whole-body hypothermia for neonates with hypoxicischemic encephalopathy
    • National Institute of Child Health and Human Development Neonatal Research Network
    • Shankaran S, Laptook AR, Ehrenkranz RA, et al; National Institute of Child Health and Human Development Neonatal Research Network. Whole-body hypothermia for neonates with hypoxicischemic encephalopathy. N Engl J Med. 2005;353(15):1574-1584
    • (2005) N Engl J Med. , vol.353 , Issue.15 , pp. 1574-1584
    • Shankaran, S.1    Laptook, A.R.2    Ehrenkranz, R.A.3
  • 3
    • 84861521265 scopus 로고    scopus 로고
    • Hypothermia for neonatal hypoxic ischemic encephalopathy: An updated systematic review and meta-analysis
    • Tagin MA, Woolcott CG, Vincer MJ, Whyte RK, Stinson DA. Hypothermia for neonatal hypoxic ischemic encephalopathy: an updated systematic review and meta-analysis. Arch Pediatr Adolesc Med. 2012;166(6):558-566
    • (2012) Arch Pediatr Adolesc Med. , vol.166 , Issue.6 , pp. 558-566
    • Tagin, M.A.1    Woolcott, C.G.2    Vincer, M.J.3    Whyte, R.K.4    Stinson, D.A.5
  • 4
    • 77957704402 scopus 로고    scopus 로고
    • Network Trial Participants. Systemic hypothermia after neonatal encephalopathy: Outcomes of neo. nEURO. network RCT
    • neo. nEURO
    • Simbruner G, Mittal RA, Rohlmann F, Muche R; neo. nEURO. network Trial Participants. Systemic hypothermia after neonatal encephalopathy: outcomes of neo. nEURO. network RCT. Pediatrics. 2010;126(4):e771-e778
    • (2010) Pediatrics. , vol.126 , Issue.4
    • Simbruner, G.1    Mittal, R.A.2    Rohlmann, F.3    Muche, R.4
  • 5
    • 13844321255 scopus 로고    scopus 로고
    • Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: Multicentre randomised trial
    • Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet. 2005;365(9460):663-670
    • (2005) Lancet. , vol.365 , Issue.9460 , pp. 663-670
    • Gluckman, P.D.1    Wyatt, J.S.2    Azzopardi, D.3
  • 6
    • 70349611684 scopus 로고    scopus 로고
    • Moderate hypothermia to treat perinatal asphyxial encephalopathy
    • TOBY Study Group
    • Azzopardi DV, Strohm B, Edwards AD, et al; TOBY Study Group. Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med. 2009;361(14):1349-1358
    • (2009) N Engl J Med. , vol.361 , Issue.14 , pp. 1349-1358
    • Azzopardi, D.V.1    Strohm, B.2    Edwards, A.D.3
  • 7
    • 84861705307 scopus 로고    scopus 로고
    • Childhood outcomes after hypothermia for neonatal encephalopathy
    • Eunice Kennedy Shriver NICHD Neonatal Research Network
    • Shankaran S, Pappas A, McDonald SA, et al; Eunice Kennedy Shriver NICHD Neonatal Research Network. Childhood outcomes after hypothermia for neonatal encephalopathy. N Engl J Med. 2012;366(22):2085-2092
    • (2012) N Engl J Med. , vol.366 , Issue.22 , pp. 2085-2092
    • Shankaran, S.1    Pappas, A.2    McDonald, S.A.3
  • 8
    • 84855910493 scopus 로고    scopus 로고
    • Seven-to eight-year follow-up of the CoolCap trial of head cooling for neonatal encephalopathy
    • CoolCap Trial Group
    • Guillet R, Edwards AD, ThoresenM, et al; CoolCap Trial Group. Seven-to eight-year follow-up of the CoolCap trial of head cooling for neonatal encephalopathy. Pediatr Res. 2012;71(2):205-209
    • (2012) Pediatr Res. , vol.71 , Issue.2 , pp. 205-209
    • Guillet, R.1    Edwards, A.D.2    Thoresen, M.3
  • 9
    • 0017199855 scopus 로고
    • Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study
    • Sarnat HB, Sarnat MS. Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch Neurol. 1976;33(10):696-705
    • (1976) Arch Neurol. , vol.33 , Issue.10 , pp. 696-705
    • Sarnat, H.B.1    Sarnat, M.S.2
  • 10
    • 77956063841 scopus 로고    scopus 로고
    • Hypothermia: A systematic review and meta-analysis of clinical trials
    • Shah PS. Hypothermia: a systematic review and meta-analysis of clinical trials. Semin Fetal Neonatal Med. 2010;15(5):238-246
    • (2010) Semin Fetal Neonatal Med. , vol.15 , Issue.5 , pp. 238-246
    • Shah, P.S.1
  • 11
    • 84858340160 scopus 로고    scopus 로고
    • Evolution of encephalopathy during whole body hypothermia for neonatal hypoxicischemic encephalopathy
    • Shankaran S, Laptook AR, Tyson JE, et al. Evolution of encephalopathy during whole body hypothermia for neonatal hypoxicischemic encephalopathy. J Pediatr. 2012;160:567-572
    • (2012) J Pediatr. , vol.160 , pp. 567-572
    • Shankaran, S.1    Laptook, A.R.2    Tyson, J.E.3
  • 12
    • 0035028936 scopus 로고    scopus 로고
    • Early Neurodegeneration after Hypoxia-Ischemia in Neonatal Rat Is Necrosis while Delayed Neuronal Death Is Apoptosis
    • Northington FJ, Ferriero DM, Graham EM, Traystman RJ, Martin LJ. Early Neurodegeneration after Hypoxia-Ischemia in Neonatal Rat Is Necrosis while Delayed Neuronal Death Is Apoptosis. Neurobiol Dis. 2001;8(2):207-219
    • (2001) Neurobiol Dis. , vol.8 , Issue.2 , pp. 207-219
    • Northington, F.J.1    Ferriero, D.M.2    Graham, E.M.3    Traystman, R.J.4    Martin, L.J.5
  • 13
    • 79952607370 scopus 로고    scopus 로고
    • Necrosis, apoptosis, and autophagy: Mechanisms of neuronal and glial cell death
    • Fricker M, Tolkovsky AM. Necrosis, apoptosis, and autophagy: mechanisms of neuronal and glial cell death. Cell Culture Tech. 2011;56:305-330
    • (2011) Cell Culture Tech. , vol.56 , pp. 305-330
    • Fricker, M.1    Tolkovsky, A.M.2
  • 14
    • 11144264169 scopus 로고    scopus 로고
    • Mechanisms of hypoxic-ischemic injury in the term infant
    • McLean C, Ferriero D. Mechanisms of hypoxic-ischemic injury in the term infant. Semin Perinatol. 2004;28(6):425-432
    • (2004) Semin Perinatol. , vol.28 , Issue.6 , pp. 425-432
    • McLean, C.1    Ferriero, D.2
  • 15
    • 0028793257 scopus 로고
    • Glutamateinduced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M, Dypbukt JM, Bonfoco E, et al. Glutamateinduced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 1995;15(4):961-973
    • (1995) Neuron. , vol.15 , Issue.4 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3
  • 16
  • 17
    • 33846818524 scopus 로고    scopus 로고
    • Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation
    • Abramov AY, Scorziello A, DuchenMR. Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation. J Neurosci. 2007;27(5):1129-1138
    • (2007) J Neurosci. , vol.27 , Issue.5 , pp. 1129-1138
    • Abramov, A.Y.1    Scorziello, A.2    Duchen, M.R.3
  • 19
    • 0029780767 scopus 로고    scopus 로고
    • Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine
    • Huang Z, Huang PL, Ma J, et al. Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J Cereb Blood Flow Metab. 1996;16(5):981-987
    • (1996) J Cereb Blood Flow Metab. , vol.16 , Issue.5 , pp. 981-987
    • Huang, Z.1    Huang, P.L.2    Ma, J.3
  • 20
    • 0029161636 scopus 로고
    • Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase
    • Brown GC. Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase. FEBS Lett. 1995;369(2-3):136-139
    • (1995) FEBS Lett. , vol.369 , Issue.2-3 , pp. 136-139
    • Brown, G.C.1
  • 21
    • 0037432615 scopus 로고    scopus 로고
    • Multiple pathways of peroxynitrite cytotoxicity
    • Szabó C. Multiple pathways of peroxynitrite cytotoxicity. Toxicol Lett. 2003;140-141:105-112
    • (2003) Toxicol Lett. , vol.140-141 , pp. 105-112
    • Szabó, C.1
  • 22
    • 0032536765 scopus 로고    scopus 로고
    • Nitric oxide mediates brain mitochondrial damage during perinatal anoxia
    • Bolaños JP, Almeida A, Medina JM. Nitric oxide mediates brain mitochondrial damage during perinatal anoxia. Brain Res. 1998;787(1):117-122
    • (1998) Brain Res. , vol.787 , Issue.1 , pp. 117-122
    • Bolaños, J.P.1    Almeida, A.2    Medina, J.M.3
  • 23
    • 0033510160 scopus 로고    scopus 로고
    • Mice deficient in interleukin-1 converting enzyme are resistant to neonatal hypoxic-ischemic brain damage
    • Liu XH, Kwon D, Schielke GP, Yang GY, Silverstein FS, Barks JD. Mice deficient in interleukin-1 converting enzyme are resistant to neonatal hypoxic-ischemic brain damage. J Cereb Blood Flow Metab. 1999;19(10):1099-1108
    • (1999) J Cereb Blood Flow Metab. , vol.19 , Issue.10 , pp. 1099-1108
    • Liu, X.H.1    Kwon, D.2    Schielke, G.P.3    Yang, G.Y.4    Silverstein, F.S.5    Barks, J.D.6
  • 25
    • 0032940020 scopus 로고    scopus 로고
    • Chemokine and inflammatory cell response to hypoxia-ischemia in immature rats
    • Bona E, Andersson AL, Blomgren K, et al. Chemokine and inflammatory cell response to hypoxia-ischemia in immature rats. Pediatr Res. 1999;45(4 pt 1):500-509
    • (1999) Pediatr Res. , vol.45 , Issue.4 PART 1 , pp. 500-509
    • Bona, E.1    Andersson, A.L.2    Blomgren, K.3
  • 26
    • 0142250820 scopus 로고    scopus 로고
    • Complement activation contributes to hypoxic-ischemic brain injury in neonatal rats
    • Cowell RM, Plane JM, Silverstein FS. Complement activation contributes to hypoxic-ischemic brain injury in neonatal rats. J Neurosci. 2003;23(28):9459-9468
    • (2003) J Neurosci. , vol.23 , Issue.28 , pp. 9459-9468
    • Cowell, R.M.1    Plane, J.M.2    Silverstein, F.S.3
  • 27
    • 77950413671 scopus 로고    scopus 로고
    • Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice
    • Harhausen D, Khojasteh U, Stahel PF, et al. Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice. J Neuroinflammation. 2010;7:15
    • (2010) J Neuroinflammation. , vol.7 , pp. 15
    • Harhausen, D.1    Khojasteh, U.2    Stahel, P.F.3
  • 28
    • 0026046920 scopus 로고
    • The mechanism of erythropoietin action
    • Koury MJ, Bondurant MC. The mechanism of erythropoietin action. Am J Kidney Dis. 1991;18:20-23
    • (1991) Am J Kidney Dis. , vol.18 , pp. 20-23
    • Koury, M.J.1    Bondurant, M.C.2
  • 29
    • 0344441759 scopus 로고    scopus 로고
    • Erythropoietin exerts neuroprotective effect in neonatal rat model of hypoxic-ischemic brain injury
    • Aydin A, Genç K, Akhisaroglu M, Yorukoglu K, Gokmen N, Gonullu E. Erythropoietin exerts neuroprotective effect in neonatal rat model of hypoxic-ischemic brain injury. Brain Dev. 2003;25(7): 494-498
    • (2003) Brain Dev. , vol.25 , Issue.7 , pp. 494-498
    • Aydin, A.1    Genç, K.2    Akhisaroglu, M.3    Yorukoglu, K.4    Gokmen, N.5    Gonullu, E.6
  • 30
    • 40949134551 scopus 로고    scopus 로고
    • Essential role for Stat5 in the neurotrophic but not in the neuroprotective effect of erythropoietin
    • Byts N, Samoylenko A, Fasshauer T, et al. Essential role for Stat5 in the neurotrophic but not in the neuroprotective effect of erythropoietin. Cell Death Differ. 2008;15(4):783-792
    • (2008) Cell Death Differ. , vol.15 , Issue.4 , pp. 783-792
    • Byts, N.1    Samoylenko, A.2    Fasshauer, T.3
  • 31
    • 33645580435 scopus 로고    scopus 로고
    • Erythropoietin downregulates bax and DP5 proapoptotic gene expression in neonatal hypoxicischemic brain injury
    • Kumral A, Genc S, Ozer E, et al. Erythropoietin downregulates bax and DP5 proapoptotic gene expression in neonatal hypoxicischemic brain injury. Biol Neonate. 2006;89(3):205-210
    • (2006) Biol Neonate. , vol.89 , Issue.3 , pp. 205-210
    • Kumral, A.1    Genc, S.2    Ozer, E.3
  • 32
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • Digicaylioglu M, Lipton SA. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature. 2001;412(6847):641-647
    • (2001) Nature. , vol.412 , Issue.6847 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.A.2
  • 33
    • 0031893945 scopus 로고    scopus 로고
    • Erythropoietin and erythropoietin receptor in the developing human central nervous system
    • Juul SE, Anderson DK, Li Y, Christensen RD. Erythropoietin and erythropoietin receptor in the developing human central nervous system. Pediatr Res. 1998;43(1):40-49
    • (1998) Pediatr Res. , vol.43 , Issue.1 , pp. 40-49
    • Juul, S.E.1    Anderson, D.K.2    Li, Y.3    Christensen, R.D.4
  • 34
    • 0034641710 scopus 로고    scopus 로고
    • Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury
    • Brines ML, Ghezzi P, Keenan S, et al. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci USA. 2000;97(19):10526-10531
    • (2000) Proc Natl Acad Sci USA. , vol.97 , Issue.19 , pp. 10526-10531
    • Brines, M.L.1    Ghezzi, P.2    Keenan, S.3
  • 35
    • 67749137294 scopus 로고    scopus 로고
    • Erythropoietin improved neurologic outcomes in newborns with hypoxic-ischemic encephalopathy
    • Zhu C, Kang W, Xu F, et al. Erythropoietin improved neurologic outcomes in newborns with hypoxic-ischemic encephalopathy. Pediatrics. 2009;124(2):e218-e226
    • (2009) Pediatrics. , vol.124 , Issue.2
    • Zhu, C.1    Kang, W.2    Xu, F.3
  • 36
    • 84867170513 scopus 로고    scopus 로고
    • Erythropoietin for neuroprotection in neonatal encephalopathy: Safety and pharmacokinetics
    • Wu YW, Bauer LA, Ballard RA, et al. Erythropoietin for neuroprotection in neonatal encephalopathy: safety and pharmacokinetics. Pediatrics. 2012;130(4):683-691
    • (2012) Pediatrics. , vol.130 , Issue.4 , pp. 683-691
    • Wu, Y.W.1    Bauer, L.A.2    Ballard, R.A.3
  • 38
    • 0036482282 scopus 로고    scopus 로고
    • Chemical and physical properties and potential mechanisms: Melatonin as a broad spectrum antioxidant and free radical scavenger
    • Tan DX, Reiter RJ, Manchester LC, et al. Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr Top Med Chem. 2002;2(2):181-197
    • (2002) Curr Top Med Chem. , vol.2 , Issue.2 , pp. 181-197
    • Tan, D.X.1    Reiter, R.J.2    Manchester, L.C.3
  • 39
    • 7644231186 scopus 로고    scopus 로고
    • Neuroprotective effects of melatonin against anoxia/aglycemia stress, as assessed by synaptic potentials and superoxide production in rat hippocampal slices
    • Uchida K, Samejima M, Okabe A, Fukuda A. Neuroprotective effects of melatonin against anoxia/aglycemia stress, as assessed by synaptic potentials and superoxide production in rat hippocampal slices. J Pineal Res. 2004;37(4):215-222
    • (2004) J Pineal Res. , vol.37 , Issue.4 , pp. 215-222
    • Uchida, K.1    Samejima, M.2    Okabe, A.3    Fukuda, A.4
  • 40
    • 33846463411 scopus 로고    scopus 로고
    • Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion
    • Welin AK, Svedin P, Lapatto R, et al. Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion. Pediatr Res. 2007;61(2): 153-158
    • (2007) Pediatr Res. , vol.61 , Issue.2 , pp. 153-158
    • Welin, A.K.1    Svedin, P.2    Lapatto, R.3
  • 41
    • 33847654606 scopus 로고    scopus 로고
    • Intravenous administration of melatonin reduces the intracerebral cellular inflammatory response following transient focal cerebral ischemia in rats
    • Lee MY, Kuan YH, Chen HY, et al. Intravenous administration of melatonin reduces the intracerebral cellular inflammatory response following transient focal cerebral ischemia in rats. J Pineal Res. 2007;42(3):297-309
    • (2007) J Pineal Res. , vol.42 , Issue.3 , pp. 297-309
    • Lee, M.Y.1    Kuan, Y.H.2    Chen, H.Y.3
  • 43
    • 84883119702 scopus 로고    scopus 로고
    • Melatonin improves short and long-term neurobehavioral deficits and attenuates hippocampal impairments after hypoxia in neonatal mice
    • Wang Z, Liu D, Zhan J, et al. Melatonin improves short and long-term neurobehavioral deficits and attenuates hippocampal impairments after hypoxia in neonatal mice. Pharmacol Res. 2013;76: 84-97
    • (2013) Pharmacol Res. , vol.76 , pp. 84-97
    • Wang, Z.1    Liu, D.2    Zhan, J.3
  • 44
    • 68549121055 scopus 로고    scopus 로고
    • Neuroprotective properties of melatonin in a model of birth asphyxia in the spiny mouse (Acomys cahirinus)
    • Hutton LC, Abbass M, Dickinson H, Ireland Z, Walker DW. Neuroprotective properties of melatonin in a model of birth asphyxia in the spiny mouse (Acomys cahirinus). Dev Neurosci. 2009;31(5): 437-451
    • (2009) Dev Neurosci. , vol.31 , Issue.5 , pp. 437-451
    • Hutton, L.C.1    Abbass, M.2    Dickinson, H.3    Ireland, Z.4    Walker, D.W.5
  • 45
    • 84873380508 scopus 로고    scopus 로고
    • Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model
    • Robertson NJ, Faulkner S, Fleiss B, et al. Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model. Brain. 2013;136(pt 1):90-105
    • (2013) Brain. , vol.136 , Issue.PART 1 , pp. 90-105
    • Robertson, N.J.1    Faulkner, S.2    Fleiss, B.3
  • 46
    • 76049118074 scopus 로고    scopus 로고
    • Cerebral magnetic resonance biomarkers in neonatal encephalopathy: A meta-analysis
    • Thayyil S, ChandrasekaranM, Taylor A, et al. Cerebral magnetic resonance biomarkers in neonatal encephalopathy: a meta-analysis. Pediatrics. 2010;125(2):e382-e395
    • (2010) Pediatrics. , vol.125 , Issue.2
    • Thayyil, S.1    Chandrasekaran, M.2    Taylor, A.3
  • 47
    • 0034755034 scopus 로고    scopus 로고
    • Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: Reduction by melatonin
    • Fulia F, Gitto E, Cuzzocrea S, et al. Increased levels of malondialdehyde and nitrite/nitrate in the blood of asphyxiated newborns: reduction by melatonin. J Pineal Res. 2001;31(4): 343-349
    • (2001) J Pineal Res. , vol.31 , Issue.4 , pp. 343-349
    • Fulia, F.1    Gitto, E.2    Cuzzocrea, S.3
  • 49
    • 0342699475 scopus 로고    scopus 로고
    • The caffeine metabolic ratio as an index of xanthine oxidase activity in clinically active and silent celiac patients
    • Boda M, Németh I, Boda D. The caffeine metabolic ratio as an index of xanthine oxidase activity in clinically active and silent celiac patients. J Pediatr Gastroenterol Nutr. 1999;29(5):546-550
    • (1999) J Pediatr Gastroenterol Nutr. , vol.29 , Issue.5 , pp. 546-550
    • Boda, M.1    Németh, I.2    Boda, D.3
  • 50
    • 84894103148 scopus 로고    scopus 로고
    • Antenatal allopurinol reduces hippocampal brain damage after acute birth asphyxia in late gestation fetal sheep
    • Kaandorp JJ, Derks JB, Oudijk MA, et al. Antenatal allopurinol reduces hippocampal brain damage after acute birth asphyxia in late gestation fetal sheep. Reprod Sci. 2014;21(2):251-259
    • (2014) Reprod Sci. , vol.21 , Issue.2 , pp. 251-259
    • Kaandorp, J.J.1    Derks, J.B.2    Oudijk, M.A.3
  • 51
    • 33748333492 scopus 로고    scopus 로고
    • Effect of N-acetylcysteine, allopurinol and vitamin E on jaundice-induced brain oxidative stress in rats
    • Karageorgos N, Patsoukis N, Chroni E, Konstantinou D, Assimakopoulos SF, Georgiou C. Effect of N-acetylcysteine, allopurinol and vitamin E on jaundice-induced brain oxidative stress in rats. Brain Res. 2006;1111(1):203-212
    • (2006) Brain Res. , vol.1111 , Issue.1 , pp. 203-212
    • Karageorgos, N.1    Patsoukis, N.2    Chroni, E.3    Konstantinou, D.4    Assimakopoulos, S.F.5    Georgiou, C.6
  • 53
    • 33644631485 scopus 로고    scopus 로고
    • Therapeutic effects of xanthine oxidase inhibitors: Renaissance half a century after the discovery of allopurinol
    • Pacher P, Nivorozhkin A, Szabó C. Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev. 2006;58(1):87-114
    • (2006) Pharmacol Rev. , vol.58 , Issue.1 , pp. 87-114
    • Pacher, P.1    Nivorozhkin, A.2    Szabó, C.3
  • 54
    • 33646375223 scopus 로고    scopus 로고
    • Early postnatal allopurinol does not improve short term outcome after severe birth asphyxia
    • Benders MJ, Bos AF, Rademaker CM, et al. Early postnatal allopurinol does not improve short term outcome after severe birth asphyxia. Arch Dis Child Fetal Neonatal Ed. 2006;91(3):F163-F165
    • (2006) Arch Dis Child Fetal Neonatal Ed. , vol.91 , Issue.3
    • Benders, M.J.1    Bos, A.F.2    Rademaker, C.M.3
  • 55
    • 33947331502 scopus 로고    scopus 로고
    • Effect of allopurinol supplementation on nitric oxide levels in asphyxiated newborns
    • Gunes T, Ozturk MA, Koklu E, Kose K, Gunes I. Effect of allopurinol supplementation on nitric oxide levels in asphyxiated newborns. Pediatr Neurol. 2007;36(1):17-24
    • (2007) Pediatr Neurol. , vol.36 , Issue.1 , pp. 17-24
    • Gunes, T.1    Ozturk, M.A.2    Koklu, E.3    Kose, K.4    Gunes, I.5
  • 56
    • 24044518724 scopus 로고    scopus 로고
    • Transplacental effects of allopurinol on suppression of oxygen free radical production in chronically instrumented fetal lamb brains during intermittent umbilical cord occlusion
    • Masaoka N, Nakajima Y, Hayakawa Y, et al. Transplacental effects of allopurinol on suppression of oxygen free radical production in chronically instrumented fetal lamb brains during intermittent umbilical cord occlusion. J Matern Fetal Neonatal Med. 2005;18(1):1-7
    • (2005) J Matern Fetal Neonatal Med. , vol.18 , Issue.1 , pp. 1-7
    • Masaoka, N.1    Nakajima, Y.2    Hayakawa, Y.3
  • 58
    • 2342662620 scopus 로고    scopus 로고
    • Glutamate receptormediated oligodendrocyte toxicity in periventricular leukomalacia: A protective role for topiramate
    • Follett PL, Deng W, Dai W, et al. Glutamate receptormediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate. J Neurosci. 2004;24(18):4412-4420
    • (2004) J Neurosci. , vol.24 , Issue.18 , pp. 4412-4420
    • Follett, P.L.1    Deng, W.2    Dai, W.3
  • 59
    • 33748413906 scopus 로고    scopus 로고
    • Neuroprotective effect of topiramate on hypoxic ischemic brain injury in neonatal rats
    • Noh MR, Kim SK, Sun W, et al. Neuroprotective effect of topiramate on hypoxic ischemic brain injury in neonatal rats. Exp Neurol. 2006;201(2):470-478
    • (2006) Exp Neurol. , vol.201 , Issue.2 , pp. 470-478
    • Noh, M.R.1    Kim, S.K.2    Sun, W.3
  • 60
    • 26244462973 scopus 로고    scopus 로고
    • Neuroprotective effects of topiramate after hypoxia-ischemia in newborn piglets
    • Schubert S, Brandl U, Brodhun M, et al. Neuroprotective effects of topiramate after hypoxia-ischemia in newborn piglets. Brain Res. 2005;1058(1-2):129-136
    • (2005) Brain Res. , vol.1058 , Issue.1-2 , pp. 129-136
    • Schubert, S.1    Brandl, U.2    Brodhun, M.3
  • 61
    • 2542527103 scopus 로고    scopus 로고
    • Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal rats
    • Liu Y, Barks JD, Xu G, Silverstein FS. Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal rats. Stroke. 2004;35(6):1460-1465
    • (2004) Stroke. , vol.35 , Issue.6 , pp. 1460-1465
    • Liu, Y.1    Barks, J.D.2    Xu, G.3    Silverstein, F.S.4
  • 62
    • 77955982968 scopus 로고    scopus 로고
    • Oral topiramate in neonates with hypoxic ischemic encephalopathy treated with hypothermia: A safety study
    • Filippi L, Poggi C, la Marca G, et al. Oral topiramate in neonates with hypoxic ischemic encephalopathy treated with hypothermia: a safety study. J Pediatr. 2010;157(3):361-366
    • (2010) J Pediatr. , vol.157 , Issue.3 , pp. 361-366
    • Filippi, L.1    Poggi, C.2    la Marca, G.3
  • 65
    • 34447105229 scopus 로고    scopus 로고
    • Autonomic cardiac control with xenon anaesthesia in patients at cardiovascular risk
    • Baumert JH, Hein M, Hecker KE, Satlow S, Schnoor J, Rossaint R. Autonomic cardiac control with xenon anaesthesia in patients at cardiovascular risk. Br J Anaesth. 2007;98(6):722-727
    • (2007) Br J Anaesth. , vol.98 , Issue.6 , pp. 722-727
    • Baumert, J.H.1    Hein, M.2    Hecker, K.E.3    Satlow, S.4    Schnoor, J.5    Rossaint, R.6
  • 66
    • 34247538981 scopus 로고    scopus 로고
    • Multicenter randomized comparison of xenon and isoflurane on left ventricular function in patients undergoing elective surgery
    • Xenon Multicenter Study Research Group
    • Wappler F, Rossaint R, Baumert J, et al; Xenon Multicenter Study Research Group. Multicenter randomized comparison of xenon and isoflurane on left ventricular function in patients undergoing elective surgery. Anesthesiology. 2007;106(3):463-471
    • (2007) Anesthesiology. , vol.106 , Issue.3 , pp. 463-471
    • Wappler, F.1    Rossaint, R.2    Baumert, J.3
  • 67
    • 77649169780 scopus 로고    scopus 로고
    • Competitive inhibition at the glycine site of the N-methyl-D-aspartate receptor mediates xenon neuroprotection against hypoxia-ischemia
    • Banks P, Franks NP, Dickinson R. Competitive inhibition at the glycine site of the N-methyl-D-aspartate receptor mediates xenon neuroprotection against hypoxia-ischemia. Anesthesiology. 2010;112(3):614-622
    • (2010) Anesthesiology. , vol.112 , Issue.3 , pp. 614-622
    • Banks, P.1    Franks, N.P.2    Dickinson, R.3
  • 68
    • 0036263574 scopus 로고    scopus 로고
    • Effects of xenon on in vitro and in vivo models of neuronal injury
    • Wilhelm S, Ma D, Maze M, Franks NP. Effects of xenon on in vitro and in vivo models of neuronal injury. Anesthesiology. 2002; 96(6):1485-1491
    • (2002) Anesthesiology. , vol.96 , Issue.6 , pp. 1485-1491
    • Wilhelm, S.1    Ma, D.2    Maze, M.3    Franks, N.P.4
  • 69
    • 41149176603 scopus 로고    scopus 로고
    • Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia
    • Hobbs C, Thoresen M, Tucker A, Aquilina K, Chakkarapani E, Dingley J. Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia. Stroke. 2008;39(4):1307-1313
    • (2008) Stroke. , vol.39 , Issue.4 , pp. 1307-1313
    • Hobbs, C.1    Thoresen, M.2    Tucker, A.3    Aquilina, K.4    Chakkarapani, E.5    Dingley, J.6
  • 70
    • 77956364049 scopus 로고    scopus 로고
    • Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs
    • Chakkarapani E, Dingley J, Liu X, et al. Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs. Ann Neurol. 2010;68(3):330-341
    • (2010) Ann Neurol. , vol.68 , Issue.3 , pp. 330-341
    • Chakkarapani, E.1    Dingley, J.2    Liu, X.3
  • 71
    • 80255132664 scopus 로고    scopus 로고
    • Involvement of neuronal nitric oxide synthase in ongoing fetal brain injury following near-term rabbit hypoxia-ischemia
    • Rao S, Lin Z, Drobyshevsky A, et al. Involvement of neuronal nitric oxide synthase in ongoing fetal brain injury following near-term rabbit hypoxia-ischemia. Dev Neurosci. 2011;33(3-4):288-298
    • (2011) Dev Neurosci. , vol.33 , Issue.3-4 , pp. 288-298
    • Rao, S.1    Lin, Z.2    Drobyshevsky, A.3
  • 72
    • 84876280439 scopus 로고    scopus 로고
    • First human use of 50% xenon inhalation during hypothermia for neonatal hypoxic ischemic encephalopathy: The "Coolxenon" Feasibility Study
    • ePAS20111660.7
    • Thoresen M, Liu X, Tooley J, et al. First human use of 50% xenon inhalation during hypothermia for neonatal hypoxic ischemic encephalopathy: the "Coolxenon" Feasibility Study. Pediatric Academic Societies. 2011:ePAS20111660.7
    • (2011) Pediatric Academic Societies.
    • Thoresen, M.1    Liu, X.2    Tooley, J.3
  • 76
    • 84886289828 scopus 로고    scopus 로고
    • Partial neuroprotection by nNOS inhibition during profound asphyxia in preterm fetal sheep
    • Drury PP, Davidson JO, van den Heuij LG, et al. Partial neuroprotection by nNOS inhibition during profound asphyxia in preterm fetal sheep. Exp Neurol. 2013;250:282-292
    • (2013) Exp Neurol. , vol.250 , pp. 282-292
    • Drury, P.P.1    Davidson, J.O.2    van den Heuij, L.G.3
  • 77
    • 80255131292 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase inhibition prevents cerebral palsy following hypoxia-ischemia in fetal rabbits: Comparison between JI-8 and 7-nitroindazole
    • Yu L, Derrick M, Ji H, et al. Neuronal nitric oxide synthase inhibition prevents cerebral palsy following hypoxia-ischemia in fetal rabbits: comparison between JI-8 and 7-nitroindazole. Dev Neurosci. 2011;33(3-4):312-319
    • (2011) Dev Neurosci. , vol.33 , Issue.3-4 , pp. 312-319
    • Yu, L.1    Derrick, M.2    Ji, H.3
  • 78
    • 84855799966 scopus 로고    scopus 로고
    • The ER-mitochondria interface: The social network of cell death
    • Grimm S. The ER-mitochondria interface: the social network of cell death. Biochim Biophys Acta. 2012;1823:327-334
    • (2012) Biochim Biophys Acta. , vol.1823 , pp. 327-334
    • Grimm, S.1
  • 79
    • 27744597285 scopus 로고    scopus 로고
    • Interaction between lipid monolayers and poloxamer 188: An X-ray reflectivity and diffraction study
    • Wu G, Majewski J, Ege C, Kjaer K, Weygand MJ, Lee KY. Interaction between lipid monolayers and poloxamer 188: an X-ray reflectivity and diffraction study. Biophys J. 2005;89(5): 3159-3173
    • (2005) Biophys J. , vol.89 , Issue.5 , pp. 3159-3173
    • Wu, G.1    Majewski, J.2    Ege, C.3    Kjaer, K.4    Weygand, M.J.5    Lee, K.Y.6
  • 80
    • 25844436908 scopus 로고    scopus 로고
    • Interaction of nonionic PEO-PPO diblock copolymers with lipid bilayers
    • Firestone MA, Seifert S. Interaction of nonionic PEO-PPO diblock copolymers with lipid bilayers. Biomacromolecules. 2005;6 (5):2678-2687
    • (2005) Biomacromolecules. , vol.6 , Issue.5 , pp. 2678-2687
    • Firestone, M.A.1    Seifert, S.2
  • 81
    • 84880605686 scopus 로고    scopus 로고
    • The membrane-active tri-block copolymer pluronic F-68 profoundly rescues rat hippocampal neurons from oxygen-glucose deprivationinduced death through early inhibition of apoptosis
    • Shelat PB, Plant LD, Wang JC, Lee E, Marks JD. The membrane-active tri-block copolymer pluronic F-68 profoundly rescues rat hippocampal neurons from oxygen-glucose deprivationinduced death through early inhibition of apoptosis. J Neurosci. 2013;33(30):12287-12299
    • (2013) J Neurosci. , vol.33 , Issue.30 , pp. 12287-12299
    • Shelat, P.B.1    Plant, L.D.2    Wang, J.C.3    Lee, E.4    Marks, J.D.5
  • 82
    • 0035316143 scopus 로고    scopus 로고
    • Amphiphilic, tri-block copolymers provide potent, membrane-targeted neuroprotection
    • Marks JD, Pan CY, Bushell T, et al. Amphiphilic, tri-block copolymers provide potent, membrane-targeted neuroprotection. FASEB J. 2001;15:1107-1109
    • (2001) FASEB J. , vol.15 , pp. 1107-1109
    • Marks, J.D.1    Pan, C.Y.2    Bushell, T.3
  • 84
    • 2442655317 scopus 로고    scopus 로고
    • Safety of purified poloxamer 188 in sickle cell disease: Phase I study of a non-ionic surfactant in the management of acute chest syndrome
    • Ballas SK, Files B, Luchtman-Jones L, et al. Safety of purified poloxamer 188 in sickle cell disease: phase I study of a non-ionic surfactant in the management of acute chest syndrome. Hemoglobin. 2004;28(2):85-102
    • (2004) Hemoglobin. , vol.28 , Issue.2 , pp. 85-102
    • Ballas, S.K.1    Files, B.2    Luchtman-Jones, L.3
  • 85
    • 77953877898 scopus 로고    scopus 로고
    • One-month intravenous toxicity studies of poloxamer 188 in male Sprague-Dawley rats and in beagle dogs
    • Duvinage C, Millecamps S, Sagnier A, et al. One-month intravenous toxicity studies of poloxamer 188 in male Sprague-Dawley rats and in beagle dogs. Toxicol Lett. 1996;88(suppl 1):101
    • (1996) Toxicol Lett. , vol.88 , Issue.SUPPL. 1 , pp. 101
    • Duvinage, C.1    Millecamps, S.2    Sagnier, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.