Disparate effects of metabolically healthy obesity in coronary heart disease and heart failure

Journal of the American College of Cardiology

Volumn 63, Issue 11, 2014, Pages 1079-1081

  Lavie, Carl J ^a,b   Milani, Richard V ^a   Ventura, Hector O ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

cardiovascular disease; coronary heart disease; fitness; heart failure; obesity

Indexed keywords

ACUTE HEART INFARCTION; BLOOD VOLUME; CARDIOVASCULAR RISK; DISEASE ASSOCIATION; HEART FAILURE; HEART OUTPUT; HEART STROKE VOLUME; HEART WORK; HUMAN; ISCHEMIC HEART DISEASE; NOTE; OBESITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; BODY MASS; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; FEMALE; FITNESS; HEART INFARCTION; MALE; CARDIOMETABOLIC RISK; CARDIOMYOPATHY; CARDIORESPIRATORY FITNESS; CARDIOVASCULAR MORTALITY; FOLLOW UP; HEART ATRIUM FIBRILLATION; HYPERTENSION; INSULIN SENSITIVITY; NORWAY; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PREVALENCE; PROGNOSIS;

CARDIOVASCULAR DISEASE; CORONARY HEART DISEASE; FITNESS; HEART FAILURE; OBESITY;

BODY MASS INDEX; CAUSE OF DEATH; FEMALE; HEART FAILURE; HUMANS; MALE; MYOCARDIAL INFARCTION; OBESITY;

EID: 84899706146     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.10.080     Document Type: Editorial

References (18)

1. C.J. Lavie, R.V. Milani, and H.O. Ventura Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss J Am Coll Cardiol 53 2009 1925 1932
2. S. Payvar, S. Kim, and S.V. Rao et al. In-hospital outcomes of percutaneous coronary interventions in extremely obese and normal-weight patients: findings from the NCDR (National Cardiovascular Data Registry) J Am Coll Cardiol 62 2013 692 696
3. M.E. Buschur, D. Smith, and D. Share et al. The burgeoning epidemic of morbid obesity in patients undergoing percutaneous coronary intervention: insight from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium J Am Coll Cardiol 62 2013 685 691
4. R.K. Masters, E.N. Reither, D.A. Powers, Y.C. Yang, A.E. Burger, and B.G. Link The impact of obesity on US mortality levels: the importance of age and cohort factors in population estimates Am J Public Health 103 2013 1895 1901
5. K.M. Flegal, B.K. Kit, H. Orpana, and B.L. Graubard Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis JAMA 309 2013 71 82
6. C.J. Lavie, M.A. Alpert, R. Arena, M.R. Mehra, R.V. Milani, and H.O. Ventura Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure J Am Coll Cardiol HF 1 2013 93 102
7. B. Mørkedal, L.J. Vatten, P.R. Romundstad, L.E. Laugsand, and I. Janszky Risk of myocardial infarction and heart failure among metabolically healthy but obese individuals: HUNT (Nord-Trøndelag Health Study), Norway J Am Coll Cardiol 63 2014 1071 1078
8. G. Calori, G. Lattuada, and L. Piemonti et al. Prevalence, metabolic features, and prognosis of metabolically healthy obese Italian individuals: the Cremona Study Diabetes Care 34 2011 210 215
9. A.D. Ogorodnikova, M. Kim, A.P. McGinn, P. Muntner, U. Khan, and R.P. Wildman Incident cardiovascular disease events in metabolically benign obese individuals Obesity 20 2012 651 659
10. M. Hamer, and E. Stamatakis Metabolically healthy obesity and risk of all-cause and cardiovascular disease mortality J Clin Endocrinol Metab 97 2012 2482 2488
11. F.B. Ortega, D.-C. Lee, and P.T. Katzmarzyk et al. The intriguing metabolically healthy but obese phenotype: cardiovascular prognosis and role of fitness Eur Heart J 34 2013 389 397
12. S. Kenchaiah, J.C. Evans, and D. Levy et al. Obesity and the risk of heart failure N Engl J Med 347 2002 305 313
13. M.A. Alpert, B.E. Terry, and M. Mulekar et al. Cardiac morphology and left ventricular function in morbidly obese patients with and without congestive heart failure and effect of weight loss Am J Cardiol 80 1997 736 740
14. C. Voulgari, N. Tentolouris, P. Dilaveris, D. Tousoulis, N. Katsilambros, and C. Stefanadis Increased heart failure risk in normal-weight people with metabolic syndrome compared with metabolically healthy obese individuals J Am Coll Cardiol 58 2011 1343 1350
15. C.J. Lavie, A. De Schutter, D. Patel, S.M. Artham, and R.V. Milani Body composition and coronary heart disease mortality: an obesity or a lean paradox? Mayo Clin Proc 86 2011 857 864
16. C.J. Lavie, A. De Schutter, D.A. Patel, A. Romero-Corral, S.M. Artham, and R.V. Milani Body composition and survival in stable coronary heart disease: impact of lean mass index and body fat in the "obesity paradox" J Am Coll Cardiol 60 2012 1374 1380
17. P.A. McAuley, E.G. Artero, and X. Sui et al. The obesity paradox, cardiorespiratory fitness, and coronary heart disease Mayo Clin Proc 87 2012 443 451
18. C.J. Lavie, L.P. Cahalin, and P. Chase et al. Impact of cardiorespiratory fitness on the obesity paradox in patients with heart failure Mayo Clin Proc 88 2013 251 258