Incident cardiovascular disease events in metabolically benign obese individuals

Obesity

Volumn 20, Issue 3, 2012, Pages 651-659

  Ogorodnikova, Alexandra D ^a   Kim, Mimi ^a   McGinn, Aileen P ^a   Muntner, Paul ^b   Khan, Unab ^a   Wildman, Rachel P ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HUMAN; INSULIN RESISTANCE; INTERMETHOD COMPARISON; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; OBESITY; OUTCOME ASSESSMENT; PHENOTYPE; PREVALENCE; RISK ASSESSMENT; RISK FACTOR; SENSITIVITY ANALYSIS; STROKE; SYNDROME DELINEATION;

ATHEROSCLEROSIS; BLOOD GLUCOSE; C-REACTIVE PROTEIN; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; INSULIN RESISTANCE; LIFE STYLE; MALE; MIDDLE AGED; OBESITY; PHENOTYPE; RISK ASSESSMENT; RISK FACTORS; UNITED STATES;

EID: 84857685253     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2011.243     Document Type: Article

References (32)

1. Blüher M. The distinction of metabolically 'healthy' from 'unhealthy' obese individuals. Curr Opin Lipidol 2010;21:38-43.
2. Iacobellis G, Ribaudo MC, Zappaterreno A, Iannucci CV, Leonetti F. Prevalence of uncomplicated obesity in an Italian obese population. Obes Res 2005;13:1116-1122.
3. Karelis AD, Brochu M, Rabasa-Lhoret R. Can we identify metabolically healthy but obese individuals (MHO)? Diabetes Metab 2004;30:569-572.
4. Stefan N, Kantartzis K, Machann J et al. Identification and characterization of metabolically benign obesity in humans. Arch Intern Med 2008;168:1609-1616.
5. Wildman RP. Healthy obesity. Curr Opin Clin Nutr Metab Care 2009;12:438-443.
6. Wildman RP, Muntner P, Reynolds K et al. The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 1999-2004). Arch Intern Med 2008;168:1617-1624.
7. Flint AJ, Hu FB, Glynn RJ et al. Excess weight and the risk of incident coronary heart disease among men and women. Obesity (Silver Spring) 2010;18:377-383.
8. Katzmarzyk PT, Janssen I, Ross R, Church TS, Blair SN. The importance of waist circumference in the definition of metabolic syndrome: prospective analyses of mortality in men. Diabetes Care 2006;29:404-409.
9. Kip KE, Marroquin OC, Kelley DE et al. Clinical importance of obesity versus the metabolic syndrome in cardiovascular risk in women: a report from the Women's Ischemia Syndrome Evaluation (WISE) study. Circulation 2004;109:706-713.
10. Meigs JB, Wilson PW, Fox CS et al. Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease. J Clin Endocrinol Metab 2006;91:2906-2912.
11. Song Y, Manson JE, Meigs JB et al. Comparison of usefulness of body mass index versus metabolic risk factors in predicting 10-year risk of cardiovascular events in women. Am J Cardiol 2007;100:1654-1658.
12. Dvorak RV, De Nino WF, Ades PA, Poehlman ET. Phenotypic characteristics associated with insulin resistance in metabolically obese but normal-weight young women. Diabetes 1999;48:2210-2214.
13. Park YW, Zhu S, Palaniappan L et al. The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994. Arch Intern Med 2003;163:427-436.
14. The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators. Am J Epidemiol 1989;129:687-702.
15. Fried LP, Borhani NO, Enright P et al. The Cardiovascular Health Study: design and rationale. Ann Epidemiol 1991;1:263-276.
16. Matthews DR, Hosker JP, Rudenski AS et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-419.
17. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972;18:499-502.
18. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106:3143-3421.
19. Ives DG, Fitzpatrick AL, Bild DE et al. Surveillance and ascertainment of cardiovascular events. The Cardiovascular Health Study. Ann Epidemiol 1995;5:278-285.
20. White AD, Folsom AR, Chambless LE et al. Community surveillance of coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) Study: methods and initial two years' experience. J Clin Epidemiol 1996;49:223-233.
21. Wildman RP, McGinn AP, Lin J et al. Cardiovascular disease risk of abdominal obesity vs. metabolic abnormalities. Obesity (Silver Spring) 2011;19:853-860.
22. Hubert HB, Feinleib M, McNamara PM, Castelli WP. Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study. Circulation 1983;67:968-977.
23. Conus F, Allison DB, Rabasa-Lhoret R et al. Metabolic and behavioral characteristics of metabolically obese but normal-weight women. J Clin Endocrinol Metab 2004;89:5013-5020.
24. Ruderman N, Chisholm D, Pi-Sunyer X, Schneider S. The metabolically obese, normal-weight individual revisited. Diabetes 1998;47:699-713.
25. McEvoy JW, Blaha MJ, Nasir K. "Metabolically benign" obesity: a wolf in sheep's clothing. Atherosclerosis, 2011;217:74-76.
26. Lin SX, Pi-Sunyer EX. Prevalence of the metabolic syndrome among US middle-aged and older adults with and without diabetes-a preliminary analysis of the NHANES 1999-2002 data. Ethn Dis 2007;17:35-39.
27. Khan UI, Wang D, Thurston RC et al. Burden of subclinical cardiovascular disease in "metabolically benign" and "at-risk" overweight and obese women: the Study of Women's Health Across the Nation (SWAN). Atherosclerosis, 2011;217:179-186.
28. Marini MA, Succurro E, Frontoni S et al. Metabolically healthy but obese women have an intermediate cardiovascular risk profile between healthy nonobese women and obese insulin-resistant women. Diabetes Care 2007;30:2145-2147.
29. Wildman RP, Muntner P, Chen J, Sutton-Tyrrell K, He J. Relation of inflammation to peripheral arterial disease in the national health and nutrition examination survey, 1999-2002. Am J Cardiol 2005;96:1579-1583.
30. Messier V, Karelis AD, Prud'homme D et al. Identifying metabolically healthy but obese individuals in sedentary postmenopausal women. Obesity (Silver Spring) 2010;18:911-917.
31. Karelis AD, Messier V, Brochu M, Rabasa-Lhoret R. Metabolically healthy but obese women: effect of an energy-restricted diet. Diabetologia 2008;51:1752-1754.
32. Shin MJ, Hyun YJ, Kim OY et al. Weight loss effect on inflammation and LDL oxidation in metabolically healthy but obese (MHO) individuals: low inflammation and LDL oxidation in MHO women. Int J Obes (Lond) 2006;30:1529-1534.