Analysis of rare variants in the C3 gene in patients with age-related macular degeneration

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Duvvari, Maheswara R ^a,b   Paun, Codrut C ^a,b   Buitendijk, Gabriëlle H S ^c   Saksens, Nicole T M ^a   Volokhina, Elena B ^a   Ristau, Tina ^d   Schoenmaker Koller, Frederieke E ^a   Van De Ven, Johannes P H ^a   Groenewoud, Joannes M M ^a   Van Den Heuvel, Lambertus P W J ^a   Hofman, Albert ^c,e   Fauser, Sascha ^d   Uitterlinden, André G ^c,e   Klaver, Caroline C W ^c   Hoyng, Carel B ^a   De Jong, Eiko K ^a,b   Den Hollander, Anneke I ^a,b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^e NETHERLANDS GENOMICS INITIATIVE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; COMPLEMENT COMPONENT C3; GLUTAMINE; LYSINE; SERINE; TRYPTOPHAN;

ADULT; AGED; ARTICLE; C3 GENE; COHORT ANALYSIS; CONTROLLED STUDY; EXON; FEMALE; GENE; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HEMOLYTIC UREMIC SYNDROME; HUMAN; MAJOR CLINICAL STUDY; MALE; NETHERLANDS; NUCLEOTIDE SEQUENCE; OVERLAPPING GENE; PATHOGENESIS; POPULATION BASED CASE CONTROL STUDY; RETINA MACULA AGE RELATED DEGENERATION; ALLELE; AMINO ACID SUBSTITUTION; CASE CONTROL STUDY; DNA SEQUENCE; GENETIC PREDISPOSITION; GENETICS; MACULAR DEGENERATION; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; SINGLE NUCLEOTIDE POLYMORPHISM; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALLELES; AMINO ACID SUBSTITUTION; CASE-CONTROL STUDIES; COMPLEMENT C3; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MACULAR DEGENERATION; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; SEVERITY OF ILLNESS INDEX;

EID: 84899699672     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094165     Document Type: Article

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