Genetic profile for five common variants associated with age-related macular degeneration in densely affected families: A novel analytic approach

European Journal of Human Genetics

Volumn 18, Issue 4, 2010, Pages 496-501

  Sobrin, Lucia ^a,b,c   Maller, Julian B ^c,d,e   Neale, Benjamin M ^c,d,f   Reynolds, Robyn C ^g   Fagerness, Jesen A ^c,d   Daly, Mark J ^b,c,d   Seddon, Johanna M ^g,h  

^a MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f KING'S COLLEGE LONDON   (United Kingdom)

^g TUFTS MEDICAL CENTER   (United States)

^h TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AMD; Complex trait; Liability threshold model; Simulation; SNPs

Indexed keywords

ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; PEDIGREE ANALYSIS; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM;

COMPUTER SIMULATION; FAMILY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LINKAGE (GENETICS); MACULAR DEGENERATION; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 77949652757     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2009.185     Document Type: Article

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