메뉴 건너뛰기




Volumn 9, Issue 4, 2014, Pages

Discovery of prognostic biomarker candidates of lacunar infarction by quantitative proteomics of microvesicles enriched plasma

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BIOINFORMATICS; CELL VACUOLE; CLINICAL ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; LACUNAR STROKE; MALE; MASS SPECTROMETRY; MICROVESICLE; NEUROPSYCHOLOGICAL TEST; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; PROGNOSIS; PROSPECTIVE STUDY; PROTEOMICS; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; RISK FACTOR; WESTERN BLOTTING; AGED; BLOOD; BLOOD CLOTTING; CHEMICAL PHENOMENA; CHROMATOGRAPHY; CLUSTER ANALYSIS; DEMOGRAPHY; FOCAL ADHESION; ISOTOPE LABELING; MEMBRANE MICROPARTICLE; METABOLISM; MIDDLE AGED; PROCEDURES; STATIC ELECTRICITY; STROKE, LACUNAR;

EID: 84899698283     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094663     Document Type: Article
Times cited : (36)

References (66)
  • 1
    • 79952596049 scopus 로고    scopus 로고
    • Differing risk factors and outcomes in ischemic stroke subtypes: Focus on lacunar stroke
    • Wardlaw JM (2011) Differing risk factors and outcomes in ischemic stroke subtypes: Focus on lacunar stroke. Future Neurol 6: 201-221.
    • (2011) Future Neurol , vol.6 , pp. 201-221
    • Wardlaw, J.M.1
  • 2
    • 66849131593 scopus 로고    scopus 로고
    • Ischemic stroke in south asians: A review of the epidemiology, pathophysiology, and ethnicity-related clinical features
    • Gunarathne A, Patel JV, Gammon B, Gill PS, Hughes EA, et al. (2009) Ischemic stroke in south asians: a review of the epidemiology, pathophysiology, and ethnicity-related clinical features. Stroke 40: e415-e423.
    • (2009) Stroke , vol.40
    • Gunarathne, A.1    Patel, J.V.2    Gammon, B.3    Gill, P.S.4    Hughes, E.A.5
  • 3
    • 79451468849 scopus 로고    scopus 로고
    • Is investigating for carotid artery disease warranted in non-cortical lacunar infarction?
    • Rajapakse A, Rajapakse S, Sharma JC (2011) Is investigating for carotid artery disease warranted in non-cortical lacunar infarction? Stroke 42: 217-220.
    • (2011) Stroke , vol.42 , pp. 217-220
    • Rajapakse, A.1    Rajapakse, S.2    Sharma, J.C.3
  • 4
    • 78549279437 scopus 로고    scopus 로고
    • Current issues in antiplatelet therapy for stroke prevention: The importance of stroke subtypes and differences between stroke and MI patients
    • Kirshner HS (2010) Current issues in antiplatelet therapy for stroke prevention: The importance of stroke subtypes and differences between stroke and MI patients. J Neurol 257: 1788-1797.
    • (2010) J Neurol , vol.257 , pp. 1788-1797
    • Kirshner, H.S.1
  • 5
    • 34547677750 scopus 로고    scopus 로고
    • Intracranial large artery disease among OCSP subtypes in ethnic South Asian ischemic stroke patients
    • DOI 10.1016/j.jns.2007.04.020, PII S0022510X07002936
    • De Silva DA, Woon FP, Pin LM, Chen CP, Chang HM, et al. (2007) Intracranial large artery disease among OCSP subtypes in ethnic South Asian ischemic stroke patients. J Neurol Sci 260: 147-149. (Pubitemid 47212220)
    • (2007) Journal of the Neurological Sciences , vol.260 , Issue.1-2 , pp. 147-149
    • De Silva, D.A.1    Woon, F.P.2    Pin, L.M.3    Chen, C.P.L.H.4    Chang, H.M.5    Wong, M.C.6
  • 6
    • 70349306869 scopus 로고    scopus 로고
    • Mild cognitive impairment in stroke patients with ischemic cerebral small-vessel disease: A forerunner of vascular dementia?
    • Grau-Olivares M, Arboix A (2009) Mild cognitive impairment in stroke patients with ischemic cerebral small-vessel disease: A forerunner of vascular dementia? Expert Rev Neurother 9: 1201-1217.
    • (2009) Expert Rev Neurother , vol.9 , pp. 1201-1217
    • Grau-Olivares, M.1    Arboix, A.2
  • 8
    • 79951525817 scopus 로고    scopus 로고
    • Quantitative analysis of human cerebrospinal fluid proteins using a combination of cysteine tagging and amine-reactive isobaric labeling
    • Giron P, Dayon L, Turck N, Hoogland C, Sanchez JC (2011) Quantitative analysis of human cerebrospinal fluid proteins using a combination of cysteine tagging and amine-reactive isobaric labeling. J Proteome Res 10: 249-258.
    • (2011) J Proteome Res , vol.10 , pp. 249-258
    • Giron, P.1    Dayon, L.2    Turck, N.3    Hoogland, C.4    Sanchez, J.C.5
  • 9
    • 79955511876 scopus 로고    scopus 로고
    • Biomarkers for stroke: In search of fingerprints
    • Bettermann K (2011) Biomarkers for stroke: in search of fingerprints. J Stroke Cerebrovasc Dis 20: 173-176.
    • (2011) J Stroke Cerebrovasc Dis , vol.20 , pp. 173-176
    • Bettermann, K.1
  • 10
    • 68249139963 scopus 로고    scopus 로고
    • Invited article: Searching for oracles? Blood biomarkers in acute stroke
    • Foerch C, Montaner J, Furie KL, Ning MM, Lo EH (2009) Invited article: searching for oracles? Blood biomarkers in acute stroke. Neurology 73: 393-399.
    • (2009) Neurology , vol.73 , pp. 393-399
    • Foerch, C.1    Montaner, J.2    Furie, K.L.3    Ning, M.M.4    Lo, E.H.5
  • 11
    • 79960829854 scopus 로고    scopus 로고
    • Blood Biomarkers of Ischemic Stroke
    • Jickling GC, Sharp FR (2011) Blood Biomarkers of Ischemic Stroke. Neurotherapeutics 8: 349-360.
    • (2011) Neurotherapeutics , vol.8 , pp. 349-360
    • Jickling, G.C.1    Sharp, F.R.2
  • 14
    • 0346097879 scopus 로고    scopus 로고
    • Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction
    • DOI 10.1093/brain/awh023
    • Hassan A, Hunt BJ, O'Sullivan M, Bell R, D'Souza R, et al. (2004) Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction. Brain 127: 212-219. (Pubitemid 38055360)
    • (2004) Brain , vol.127 , Issue.1 , pp. 212-219
    • Hassan, A.1    Hunt, B.J.2    O'Sullivan, M.3    Bell, R.4    D'Souza, R.5    Jeffery, S.6    Bamford, J.M.7    Markus, H.S.8
  • 15
    • 77951218980 scopus 로고    scopus 로고
    • The levels of inflammatory markers in the treatment of stroke study (limits): Inflammatory biomarkers as risk predictors after lacunar stroke
    • Elkind MSV, Luna JM, Coffey CS, McClure LA, Liu KM, et al. (2010) The levels of inflammatory markers in the treatment of stroke study (limits): Inflammatory biomarkers as risk predictors after lacunar stroke. Int J Stroke 5: 117-125.
    • (2010) Int J Stroke , vol.5 , pp. 117-125
    • Elkind, M.S.V.1    Luna, J.M.2    Coffey, C.S.3    McClure, L.A.4    Liu, K.M.5
  • 16
    • 84886945841 scopus 로고    scopus 로고
    • Towards a 'systems'-level understanding of the nervous system and its disorders
    • Qureshi IA, Mehler MF (2013) Towards a 'systems'-level understanding of the nervous system and its disorders. Trends Neurosci 36: 674-684.
    • (2013) Trends Neurosci , vol.36 , pp. 674-684
    • Qureshi, I.A.1    Mehler, M.F.2
  • 19
    • 79960364758 scopus 로고    scopus 로고
    • Oxygen-glucose deprivation increases the enzymatic activity and the microvesiclemediated release of ectonucleotidases in the cells composing the blood-brain barrier
    • Ceruti S, Colombo L, Magni G, Viganó F, Boccazzi M, et al. (2011) Oxygen-glucose deprivation increases the enzymatic activity and the microvesiclemediated release of ectonucleotidases in the cells composing the blood-brain barrier. Neurochemistry International 59: 259-271.
    • (2011) Neurochemistry International , vol.59 , pp. 259-271
    • Ceruti, S.1    Colombo, L.2    Magni, G.3    Viganó, F.4    Boccazzi, M.5
  • 20
    • 84862229138 scopus 로고    scopus 로고
    • Quantitative secretomic analysis of Trichoderma reesei strains reveals enzymatic composition for lignocellulosic biomass degradation
    • Adav SS, Chao LT, Sze SK (2012) Quantitative secretomic analysis of Trichoderma reesei strains reveals enzymatic composition for lignocellulosic biomass degradation. Mol Cell Proteomics 11: M111.012419.
    • (2012) Mol Cell Proteomics , vol.11
    • Adav, S.S.1    Chao, L.T.2    Sze, S.K.3
  • 21
    • 77953142134 scopus 로고    scopus 로고
    • Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes
    • Park JE, Tan HS, Datta A, Lai RC, Zhang H, et al. (2010) Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol Cell Proteomics 9: 1085-1099.
    • (2010) Mol Cell Proteomics , vol.9 , pp. 1085-1099
    • Park, J.E.1    Tan, H.S.2    Datta, A.3    Lai, R.C.4    Zhang, H.5
  • 22
    • 73649107287 scopus 로고    scopus 로고
    • Phenotyping of an in vitro model of ischemic penumbra by iTRAQ-based shotgun quantitative proteomics
    • Datta A, Park JE, Li X, Zhang H, Ho ZS, et al. (2010) Phenotyping of an in vitro model of ischemic penumbra by iTRAQ-based shotgun quantitative proteomics. J Prot Res 9: 472-484.
    • (2010) J Prot Res , vol.9 , pp. 472-484
    • Datta, A.1    Park, J.E.2    Li, X.3    Zhang, H.4    Ho, Z.S.5
  • 23
    • 80655138710 scopus 로고    scopus 로고
    • Quantitative neuroproteomics of an in vivo rodent model of focal cerebral ischemia/ reperfusion injury reveals a temporal regulation of novel pathophysiological molecular markers
    • Datta A, Jingru Q, Khor TH, Teo MT, Heese K, et al. (2011) Quantitative neuroproteomics of an in vivo rodent model of focal cerebral ischemia/ reperfusion injury reveals a temporal regulation of novel pathophysiological molecular markers. J Prot Res 10: 5199-5213.
    • (2011) J Prot Res , vol.10 , pp. 5199-5213
    • Datta, A.1    Jingru, Q.2    Khor, T.H.3    Teo, M.T.4    Heese, K.5
  • 24
    • 84884368222 scopus 로고    scopus 로고
    • Quantitative Clinical Proteomic Study of Autopsied Human Infarcted Brain Specimens to Elucidate the Deregulated Pathways in Ischemic Stroke Pathology
    • Datta A, Akatsu H, Heese K, Sze SK (2013) Quantitative Clinical Proteomic Study of Autopsied Human Infarcted Brain Specimens to Elucidate the Deregulated Pathways in Ischemic Stroke Pathology. J Proteomics 91: 556-568.
    • (2013) J Proteomics , vol.91 , pp. 556-568
    • Datta, A.1    Akatsu, H.2    Heese, K.3    Sze, S.K.4
  • 25
    • 84893725125 scopus 로고    scopus 로고
    • Novel pathophysiological markers are revealed by iTRAQ-based quantitative clinical proteomics approach in vascular dementia
    • Datta A, Qian J, Chong R, Kalaria RN, Francis P, et al. (2014) Novel pathophysiological markers are revealed by iTRAQ-based quantitative clinical proteomics approach in vascular dementia. J Proteomics 99C: 54-67.
    • (2014) J Proteomics , vol.99 C , pp. 54-67
    • Datta, A.1    Qian, J.2    Chong, R.3    Kalaria, R.N.4    Francis, P.5
  • 26
    • 0033982043 scopus 로고    scopus 로고
    • Design of ESPRIT: An international randomized trial for secondary prevention after non-disabling cerebral ischaemia of arterial origin
    • De Schryver ELLM (2000) Design of ESPRIT: An international randomized trial for secondary prevention after non-disabling cerebral ischaemia of arterial origin. Cerebrovascular Diseases 10: 147-150.
    • (2000) Cerebrovascular Diseases , vol.10 , pp. 147-150
    • De Schryver, E.L.L.M.1
  • 27
    • 79954893515 scopus 로고    scopus 로고
    • The prognostic effects of poststroke cognitive impairment no dementia and domainspecific cognitive impairments in nondisabled ischemic stroke patients
    • Narasimhalu K, Ang S, De Silva DA, Wong MC, Chang HM, et al. (2011) The prognostic effects of poststroke cognitive impairment no dementia and domainspecific cognitive impairments in nondisabled ischemic stroke patients. Stroke 42: 883-888.
    • (2011) Stroke , vol.42 , pp. 883-888
    • Narasimhalu, K.1    Ang, S.2    De Silva, D.A.3    Wong, M.C.4    Chang, H.M.5
  • 28
    • 0024229234 scopus 로고
    • Recovery of motor function after stroke
    • Bonita R, Beaglehole R (1988) Modification of rankin scale: Recovery of motor function after stroke. Stroke 19: 1497-1500. (Pubitemid 19005804)
    • (1988) Stroke , vol.19 , Issue.12 , pp. 1497-1500
    • Bonita, R.1    Beaglehole, R.2
  • 29
  • 31
    • 0034110470 scopus 로고    scopus 로고
    • How well does the Oxfordshire Community Stroke Project classification predict the site and size of the infarct on brain imaging?
    • DOI 10.1136/jnnp.68.5.558
    • Mead GE, Lewis SC, Wardlaw JM, Dennis MS, Warlow CP (2000) How well does the Oxfordshire community stroke project classification predict the site and size of the infarct on brain imaging? J Neurol Neurosurg Psychiatry 68: 558-562. (Pubitemid 30248817)
    • (2000) Journal of Neurology Neurosurgery and Psychiatry , vol.68 , Issue.5 , pp. 558-562
    • Mead, G.E.1    Lewis, S.C.2    Wardlaw, J.M.3    Dennis, M.S.4    Warlow, C.P.5
  • 32
    • 84864817826 scopus 로고    scopus 로고
    • Characterization of membrane-shed microvesicles from cytokine-stimulated β-cells using proteomics strategies
    • Palmisano G, Jensen S, Le Bihan MC, Lainé J, McGuire JN, et al. (2012) Characterization of membrane-shed microvesicles from cytokine-stimulated β-cells using proteomics strategies. Mol Cell Proteomics 11: 230-243.
    • (2012) Mol Cell Proteomics , vol.11 , pp. 230-243
    • Palmisano, G.1    Jensen, S.2    Le Bihan, M.C.3    Lainé, J.4    McGuire, J.N.5
  • 33
    • 84885615128 scopus 로고    scopus 로고
    • Microvesicle protein levels are associated with increased risk for future vascular events and mortality in patients with clinically manifest vascular disease
    • Kanhai DA, Visseren FLJ, Van Der Graaf Y, Schoneveld AH, Catanzariti LM, et al. (2013) Microvesicle protein levels are associated with increased risk for future vascular events and mortality in patients with clinically manifest vascular disease. Int J Cardiol 168: 2358-2363.
    • (2013) Int J Cardiol , vol.168 , pp. 2358-2363
    • Kanhai, D.A.1    Visseren, F.L.J.2    Van Der Graaf, Y.3    Schoneveld, A.H.4    Catanzariti, L.M.5
  • 34
    • 82755198858 scopus 로고    scopus 로고
    • Electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) versus strong cation exchange (SCX) for fractionation of iTRAQ-labeled peptides
    • Hao P, Qian J, Ren Y, Sze SK (2011) Electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) versus strong cation exchange (SCX) for fractionation of iTRAQ-labeled peptides. J Proteome Res 10: 5568-5574.
    • (2011) J Proteome Res , vol.10 , pp. 5568-5574
    • Hao, P.1    Qian, J.2    Ren, Y.3    Sze, S.K.4
  • 35
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • Huang da W, Sherman BT, Lempicki RA (2009) Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37: 1-13.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 37
    • 79956260679 scopus 로고    scopus 로고
    • A systematic analysis of the effects of increasing degrees of serum immunodepletion in terms of depth of coverage and other key aspects in top-down and bottom-up proteomic analyses
    • Smith MPW, Wood SL, Zougman A, Ho JTC, Peng J, et al. (2011) A systematic analysis of the effects of increasing degrees of serum immunodepletion in terms of depth of coverage and other key aspects in top-down and bottom-up proteomic analyses. Proteomics 11: 2222-2235.
    • (2011) Proteomics , vol.11 , pp. 2222-2235
    • Smith, M.P.W.1    Wood, S.L.2    Zougman, A.3    Ho, J.T.C.4    Peng, J.5
  • 38
    • 80052552293 scopus 로고    scopus 로고
    • A systematic analysis of eluted fraction of plasma post immunoaffinity depletion: Implications in biomarker discovery
    • Yadav AK, Bhardwaj G, Basak T, Kumar D, Ahmad S, et al. (2011) A systematic analysis of eluted fraction of plasma post immunoaffinity depletion: Implications in biomarker discovery. PLoS ONE 6: art. no. e24442.
    • (2011) PLoS ONE , vol.6
    • Yadav, A.K.1    Bhardwaj, G.2    Basak, T.3    Kumar, D.4    Ahmad, S.5
  • 39
    • 84887490947 scopus 로고    scopus 로고
    • Quantitative proteomic analysis by iTRAQ for identification of candidate biomarkers in plasma from acute respiratory distress syndrome patients
    • Chen X, Shan Q, Jiang L, Zhu B, Xi X (2013) Quantitative proteomic analysis by iTRAQ for identification of candidate biomarkers in plasma from acute respiratory distress syndrome patients. Biochemical and Biophysical Research Communications 441: 1-6.
    • (2013) Biochemical and Biophysical Research Communications , vol.441 , pp. 1-6
    • Chen, X.1    Shan, Q.2    Jiang, L.3    Zhu, B.4    Xi, X.5
  • 40
    • 60649108665 scopus 로고    scopus 로고
    • Inter-alpha-trypsin inhibitor heavy chain 4 is a novel marker of acute ischemic stroke
    • Kashyap RS, Nayak AR, Deshpande PS, Kabra D, Purohit HJ, et al. (2009) Inter-alpha-trypsin inhibitor heavy chain 4 is a novel marker of acute ischemic stroke. Clinica Chimica Acta 402: 160-163.
    • (2009) Clinica Chimica Acta , vol.402 , pp. 160-163
    • Kashyap, R.S.1    Nayak, A.R.2    Deshpande, P.S.3    Kabra, D.4    Purohit, H.J.5
  • 41
    • 33645721632 scopus 로고    scopus 로고
    • Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins
    • Anderson L, Hunter CL (2006) Quantitative mass spectrometric multiple reaction monitoring assays for major plasma proteins. Mol Cell Proteomics 5: 573-588.
    • (2006) Mol Cell Proteomics , vol.5 , pp. 573-588
    • Anderson, L.1    Hunter, C.L.2
  • 43
    • 77956404647 scopus 로고    scopus 로고
    • Exosomes: Extracellular organelles important in intercellular communication
    • Mathivanan S, Ji H, Simpson RJ (2010) Exosomes: extracellular organelles important in intercellular communication. J Proteomics 73: 1907-1920.
    • (2010) J Proteomics , vol.73 , pp. 1907-1920
    • Mathivanan, S.1    Ji, H.2    Simpson, R.J.3
  • 44
    • 69249127810 scopus 로고    scopus 로고
    • Potential roles of cell-derived microparticles in ischemic brain disease
    • Horstman LL, Jy W, Bidot CJ, Nordberg ML, Minagar A, et al. (2009) Potential roles of cell-derived microparticles in ischemic brain disease. Neurol Res 31: 799-806.
    • (2009) Neurol Res , vol.31 , pp. 799-806
    • Horstman, L.L.1    Jy, W.2    Bidot, C.J.3    Nordberg, M.L.4    Minagar, A.5
  • 46
    • 0037338557 scopus 로고    scopus 로고
    • Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia?
    • Wardlaw JM, Sandercock PA, Dennis MS, Starr J (2003) Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia? Stroke 34: 806-812.
    • (2003) Stroke , vol.34 , pp. 806-812
    • Wardlaw, J.M.1    Sandercock, P.A.2    Dennis, M.S.3    Starr, J.4
  • 47
    • 82355164323 scopus 로고    scopus 로고
    • Correlation of levels of neuronal and glial markers with radiological measures of infarct volume in ischaemic stroke: A systematic review
    • Ahmad O, Wardlaw J, Whiteley WN (2012) Correlation of levels of neuronal and glial markers with radiological measures of infarct volume in ischaemic stroke: a systematic review. Cerebrovascular Diseases 33: 47-54.
    • (2012) Cerebrovascular Diseases , vol.33 , pp. 47-54
    • Ahmad, O.1    Wardlaw, J.2    Whiteley, W.N.3
  • 48
    • 65549135642 scopus 로고    scopus 로고
    • Blood markers for the prognosis of ischemic stroke: A systematic review
    • Whiteley W, Chong WL, Sengupta A, Sandercock P (2009) Blood markers for the prognosis of ischemic stroke: A systematic review. Stroke 40: e380-e389.
    • (2009) Stroke , vol.40
    • Whiteley, W.1    Chong, W.L.2    Sengupta, A.3    Sandercock, P.4
  • 49
    • 75749154495 scopus 로고    scopus 로고
    • Recreation of the terminal events in physiological integrin activation
    • Ye F, Hu G, Taylor D, Ratnikov B, Bobkov AA, et al. (2010) Recreation of the terminal events in physiological integrin activation. J Cell Biol 188: 157-173.
    • (2010) J Cell Biol , vol.188 , pp. 157-173
    • Ye, F.1    Hu, G.2    Taylor, D.3    Ratnikov, B.4    Bobkov, A.A.5
  • 51
    • 84857523273 scopus 로고    scopus 로고
    • In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling
    • doi:10.1182/blood-2011-09-381400
    • Nishimura S, Manabe I, Nagasaki M, Kakuta S, Iwakura Y, et al. (2011) In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling. Blood doi:10.1182/blood-2011-09-381400.
    • (2011) Blood
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3    Kakuta, S.4    Iwakura, Y.5
  • 52
    • 0037271306 scopus 로고    scopus 로고
    • Scientific and therapeutic advances in antiplatelet therapy
    • DOI 10.1038/nrd985
    • Bhatt DL, Topol EJ (2003) Scientific and therapeutic advances in antiplatelet therapy. Nature Review Drug Discovery 2: 15-28. (Pubitemid 37361621)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.1 , pp. 15-28
    • Bhatt, D.L.1    Topol, E.J.2
  • 53
    • 0026674874 scopus 로고
    • Fibrinogen and viscosity as risk factors for subsequent cardiovascular events in stroke survivors
    • Resch KL, Ernst E, Matrai A, Paulsen HF (1992) Fibrinogen and viscosity as risk factors for subsequent cardiovascular events in stroke survivors. Ann Intern Med 117: 371-375.
    • (1992) Ann Intern Med , vol.117 , pp. 371-375
    • Resch, K.L.1    Ernst, E.2    Matrai, A.3    Paulsen, H.F.4
  • 54
    • 0036044246 scopus 로고    scopus 로고
    • Fibrinogen and the amount of leukoaraiosis in patients with symptomatic small-vessel disease
    • DOI 10.1159/000066161
    • Marti-Fabregas J, Valencia C, Pujol J, Garcia-Sanchez C, Marti-Vilalta JL (2002) Fibrinogen and the amount of leukoaraiosis in patients with symptomatic small-vessel disease. Eur Neurol 48: 185-190. (Pubitemid 44858311)
    • (2002) European Neurology , vol.48 , Issue.4 , pp. 185-190
    • Marti-Fabregas, J.1    Valencia, C.2    Pujol, J.3    Garcia-Sanchez, C.4    Marti-Vilalta, J.-L.5
  • 55
    • 33748988163 scopus 로고    scopus 로고
    • Association of serial biochemical markers with acute ischemic stroke: The National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator Stroke Study
    • DOI 10.1161/01.STR.0000242290.01174.9e, PII 0000767020061000000019
    • Jauch EC, Lindsell C, Broderick J, Fagan SC, Tilley BC, et al. (2006) Association of serial biochemical markers with acute ischemic stroke: the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator Stroke Study. Stroke 37: 2508-2513. (Pubitemid 44454670)
    • (2006) Stroke , vol.37 , Issue.10 , pp. 2508-2513
    • Jauch, E.C.1    Lindsell, C.2    Broderick, J.3    Fagan, S.C.4    Tilley, B.C.5    Levine, S.R.6
  • 57
    • 77953533246 scopus 로고    scopus 로고
    • Cerebral small vessel disease: From pathogenesis and clinical characteristics to therapeutic challenges
    • Pantoni L (2010) Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 9: 689-701.
    • (2010) Lancet Neurol , vol.9 , pp. 689-701
    • Pantoni, L.1
  • 59
    • 58149098053 scopus 로고    scopus 로고
    • Serum albumin at admission for prediction of functional outcome in ischaemic stroke patients
    • Cho YM, Choi IS, Bian RX, Kim JH, Han JY, et al. (2008) Serum albumin at admission for prediction of functional outcome in ischaemic stroke patients. Neurol Sci 29: 445-449.
    • (2008) Neurol Sci , vol.29 , pp. 445-449
    • Cho, Y.M.1    Choi, I.S.2    Bian, R.X.3    Kim, J.H.4    Han, J.Y.5
  • 60
    • 65449165296 scopus 로고    scopus 로고
    • Serum albumin in ischemic stroke patients: The higher the better. The Bergen Stroke Study
    • Idicula TT, Waje-Andreassen U, Brogger J, Naess H, Thomassen L (2009) Serum albumin in ischemic stroke patients: the higher the better. The Bergen Stroke Study. Cerebrovasc Dis 28: 13-17.
    • (2009) Cerebrovasc Dis , vol.28 , pp. 13-17
    • Idicula, T.T.1    Waje-Andreassen, U.2    Brogger, J.3    Naess, H.4    Thomassen, L.5
  • 61
    • 0035133027 scopus 로고    scopus 로고
    • Human albumin therapy of acute ischemic stroke: Marked neuroprotective efficacy at moderate doses and with a broad therapeutic window
    • Belayev L, Liu Y, Zhao W, Busto R, Ginsberg MD (2001) Human albumin therapy of acute ischemic stroke: marked neuroprotective efficacy at moderate doses and with a broad therapeutic window. Stroke 32: 553-560. (Pubitemid 32155250)
    • (2001) Stroke , vol.32 , Issue.2 , pp. 553-560
    • Belayev, L.1    Liu, Y.2    Zhao, W.3    Busto, R.4    Ginsberg, M.D.5
  • 62
    • 79955370882 scopus 로고    scopus 로고
    • The Albumin in Acute Stroke Part 1 Trial: An exploratory efficacy analysis
    • Hill MD, Martin RH, Palesch YY, Tamariz D, Waldman BD, et al. (2011) The Albumin in Acute Stroke Part 1 Trial: an exploratory efficacy analysis. Stroke 42: 1621-1625.
    • (2011) Stroke , vol.42 , pp. 1621-1625
    • Hill, M.D.1    Martin, R.H.2    Palesch, Y.Y.3    Tamariz, D.4    Waldman, B.D.5
  • 63
    • 38149027855 scopus 로고    scopus 로고
    • Albumin therapy improves local vascular dynamics in a rat model of primary microvascular thrombosis: A two-photon laser-scanning microscopy study
    • Nimmagadda A, Park HP, Prado R, Ginsberg MD (2008) Albumin therapy improves local vascular dynamics in a rat model of primary microvascular thrombosis: a two-photon laser-scanning microscopy study. Stroke 39: 198-204.
    • (2008) Stroke , vol.39 , pp. 198-204
    • Nimmagadda, A.1    Park, H.P.2    Prado, R.3    Ginsberg, M.D.4
  • 65
    • 66849097996 scopus 로고    scopus 로고
    • Update of the stroke therapy academic industry roundtable preclinical recommendations
    • Fisher M, Feuerstein G, Howells DW, Hurn PD, Kent TA, et al. (2009) Update of the stroke therapy academic industry roundtable preclinical recommendations. Stroke 40: 2244-2250.
    • (2009) Stroke , vol.40 , pp. 2244-2250
    • Fisher, M.1    Feuerstein, G.2    Howells, D.W.3    Hurn, P.D.4    Kent, T.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.