Is investigating for carotid artery disease warranted in non-cortical lacunar infarction?

Stroke

Volumn 42, Issue 1, 2011, Pages 217-220

  Rajapakse, Anoja ^a   Rajapakse, Senaka ^b   Sharma, Jagdish C ^c,d  

^a Newark Hospital ^*  (United Kingdom)

^b UNIVERSITY OF COLOMBO   (Sri Lanka)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d LINCOLN COUNTY HOSPITAL   (United Kingdom)

Author keywords

Carotid artery disease; Lacunar infarct; Stroke

Indexed keywords

ATHEROSCLEROTIC PLAQUE; BLOOD BRAIN BARRIER; BRAIN INFARCTION; CARDIOVASCULAR RISK; CAROTID ARTERY DISEASE; CAROTID ARTERY OBSTRUCTION; CAROTID ENDARTERECTOMY; GENETIC POLYMORPHISM; HEART ATRIUM FIBRILLATION; HUMAN; NON CORTICAL LACUNAR INFARCTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; STROKE;

BRAIN INFARCTION; CAROTID STENOSIS; HUMANS; RECURRENCE; RISK FACTORS;

EID: 79451468849     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.110.600064     Document Type: Review

References (49)

1. Bamford J, Sandercock P, Dennis M, Burn J, Warlow C. Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet. 1991;337:1521-1526.
2. Bamford J, Sandercock P, Jones L, Warlow C. The natural history of lacunar infarction: the Oxfordshire Community Stroke Project. Stroke. 1987;18:545-551.
3. Fisher CM. The arterial lesions underlying lacunes. Acta Neuropathol. 1968;12:1-15.
4. Bamford JM, Warlow CP. Evolution and testing of the lacunar hypothesis. Stroke. 1988;19:1074-1082.
5. Bamford J. The lacunar hypothesis. J Neurol Neurosurg Psychiatry. 1990;53:819.
6. Wardlaw JM. What is a lacune? Stroke. 2008;39:2921-2922.
7. Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, Marsh EE III. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24:35-41.
8. Potter G, Doubal F, Jackson C, Sudlow C, Dennis M, Wardlaw J. Associations of clinical stroke misclassification ('clinical-imaging dissociation') in acute ischemic stroke. Cerebrovasc Dis. 29:395-402.
9. Stroke-National Clinical Guideline for Diagnosis and Initial Management of Acute Stroke and Transient Ischaemic Attack (TIA). London: Royal College of Physicians; 2008.
10. Sharma JC, Vassallo M, Ross IN. ProFESS trial: any lessons to learn for future anti-platelet trials? Int J Stroke. 2009;4:458-460.
11. Fisher CM. Lacunes: small, deep cerebral infarcts. Neurology. 1965;15: 774-784.
12. Gan R, Sacco RL, Kargman DE, Roberts JK, Boden-Albala B, Gu Q. Testing the validity of the lacunar hypothesis: the Northern Manhattan Stroke Study experience. Neurology. 1997;48:1204-1211.
13. Jackson C, Sudlow C. Are lacunar strokes really different? A systematic review of differences in risk factor profiles between lacunar and nonlacunar infarcts. Stroke. 2005;36:891-901.
14. Mead GE, Lewis SC, Wardlaw JM, Dennis MS, Warlow CP. Severe ipsilateral carotid stenosis and middle cerebral artery disease in lacunar ischaemic stroke: innocent bystanders? J Neurol. 2002;249:266-271.
15. Patton N, Aslam T, Macgillivray T, Pattie A, Deary IJ, Dhillon B. Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures. J Anat. 2005;206:319-348.
16. Doubal FN, MacGillivray TJ, Hokke PE, Dhillon B, Dennis MS, Wardlaw JM. Differences in retinal vessels support a distinct vasculopathy causing lacunar stroke. Neurology. 2009;72:1773-1778.
17. Lindley RI, Wang JJ, Wong MC, Mitchell P, Liew G, Hand P, Wardlaw J, De Silva DA, Baker M, Rochtchina E, Chen C, Hankey GJ, Chang HM, Fung VS, Gomes L, Wong TY. Retinal microvasculature in acute lacunar stroke: a cross-sectional study. Lancet Neurol. 2009;8:628-634.
18. Wardlaw JM, Doubal F, Armitage P, Chappell F, Carpenter T, Munoz Maniega S, Farrall A, Sudlow C, Dennis M, Dhillon B. Lacunar stroke is associated with diffuse blood- brain barrier dysfunction. Ann Neurol. 2009;65:194-202.
19. Wardlaw JM, Sandercock PA, Dennis MS, Starr J. Is breakdown of the blood- brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia? Stroke. 2003;34:806-812.
20. Tomimoto H, Akiguchi I, Suenaga T, Nishimura M, Wakita H, Nakamura S, Kimura J. Alterations of the blood- brain barrier and glial cells in white-matter lesions in cerebrovascular and Alzheimer's disease patients. Stroke. 1996;27:2069-2074.
21. Hassan A, Hunt BJ, O'Sullivan M, Parmar K, Bamford JM, Briley D, Brown MM, Thomas DJ, Markus HS. Markers of endothelial dysfunction in lacunar infarction and ischaemic leukoaraiosis. Brain. 2003;126: 424-432.
22. Wardlaw JM, Lewis SC, Keir SL, Dennis MS, Shenkin S. Cerebral microbleeds are associated with lacunar stroke defined clinically and radiologically, independently of white matter lesions. Stroke. 2006;37: 2633-2636.
23. Wardlaw JM, Farrall A, Armitage PA, Carpenter T, Chappell F, Doubal F, Chowdhury D, Cvoro V, Dennis MS. Changes in background blood- brain barrier integrity between lacunar and cortical ischemic stroke subtypes. Stroke. 2008;39:1327-1332.
24. Hassan A, Hunt BJ, O'Sullivan M, Bell R, D'Souza R, Jeffery S, Bamford JM, Markus HS. Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction. Brain. 2004;127: 212-219.
25. Jackson C, Sudlow C. Comparing risks of death and recurrent vascular events between lacunar and non-lacunar infarction. Brain. 2005;128: 2507-2517.
26. Salgado AV, Ferro JM, Gouveia-Oliveira A. Long-term prognosis of first-ever lacunar strokes. A hospital-based study. Stroke. 1996;27: 661-666.
27. Jackson CA, Hutchison A, Dennis MS, Wardlaw JM, Lewis SC, Sudlow CL. Differences between ischemic stroke subtypes in vascular outcomes support a distinct lacunar ischemic stroke arteriopathy: a prospective, hospital-based study. Stroke. 2009;40:3679-3684.
28. Evans A, Perez I, Yu G, Kalra L. Should stroke subtype influence anticoagulation decisions to prevent recurrence in stroke patients with atrial fibrillation? Stroke. 2001;32:2828-2832.
29. Arboix A, Font A, Garro C, Garcia-Eroles L, Comes E, Massons J. Recurrent lacunar infarction following a previous lacunar stroke: a clinical study of 122 patients. J Neurol Neurosurg Psychiatry. 2007;78:1392-1394.
30. Inzitari D, Eliasziw M, Sharpe BL, Fox AJ, Barnett HJ. Risk factors and outcome of patients with carotid artery stenosis presenting with lacunar stroke. North American Symptomatic Carotid Endarterectomy Trial group. Neurology. 2000;54:660-666.
31. Boiten J, Lodder J. Lacunar infarcts. Pathogenesis and validity of the clinical syndromes. Stroke. 1991;22:1374-1378.
32. Boiten JR, Slattery PM, Warlow CP. Ischaemic lacunar stroke in the European Carotid Surgery Trial. Cerebrovasc Dis. 1996;6:281-287.
33. Landi G, Anzalone N, Cella E, Boccardi E, Musicco M. Are sensorimotor strokes lacunar strokes? A case- control study of lacunar and non-lacunar infarcts. J Neurol Neurosurg Psychiatry. 1991;54:1063-1068.
34. Norrving B, Cronqvist S. Clinical and radiologic features of lacunar versus nonlacunar minor stroke. Stroke. 1989;20:59-64.
35. Tegeler CH, Shi F, Morgan T. Carotid stenosis in lacunar stroke. Stroke. 1991;22:1124-1128.
36. Mead GE, Shingler H, Farrell A, O'Neill PA, McCollum CN. Carotid disease in acute stroke. Age Ageing. 1998;27:677-682.
37. Donnan GA, Tress BM, Bladin PF. A prospective study of lacunar infarction using computerized tomography. Neurology. 1982;32:49-56.
38. Ghika J, Bogousslavsky J, Regli F. Infarcts in the territory of the deep perforators from the carotid system. Neurology. 1989;39:507-512.
39. Horowitz DR, Tuhrim S, Weinberger JM, Rudolph SH. Mechanisms in lacunar infarction. Stroke. 1992;23:325-327.
40. Kappelle LJ, Koudstaal PJ, van Gijn J, Ramos LM, Keunen JE. Carotid angiography in patients with lacunar infarction. A prospective study. Stroke. 1988;19:1093-1096.
41. Pullicino P, Nelson RF, Kendall BE, Marshall J. Small deep infarcts diagnosed on computed tomography. Neurology. 1980;30:1090-1096.
42. Mead GE, Wardlaw JM, Lewis SC, McDowall M, Dennis MS. Can simple clinical features be used to identify patients with severe carotid stenosis on Doppler ultrasound? J Neurol Neurosurg Psychiatry. 1999; 66:16-19.
43. Barnett HJ, Gunton RW, Eliasziw M, Fleming L, Sharpe B, Gates P, Meldrum H. Causes and severity of ischemic stroke in patients with internal carotid artery stenosis. JAMA. 2000;283:1429-1436. (Pubitemid 30151821)
44. Homburg PJ, Rozie S, van Gils MJ, Jansen T, de Weert TT, Dippel DW, van der Lugt A. Atherosclerotic plaque ulceration in the symptomatic internal carotid artery is associated with nonlacunar ischemic stroke. Stroke. 2010;41:1151-1156.
45. MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis. European Carotid Surgery Trialists' Collaborative Group. Lancet. 1991; 337:1235-1243.
46. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial collaborators. N Engl J Med. 1991;325:445-453.
47. DSP Team. Implementing the National Stroke Strategy-An Imaging Guide. Department of Health, NHS, UK. 2008:12-16.
48. Wardlaw JM, Mielke O. Early signs of brain infarction at CT: observer reliability and outcome after thrombolytic treatment-systematic review. Radiology. 2005;235:444-453.
49. Arboix A, Marti-Vilalta JL, Pujol J, Sanz M. Lacunar cerebral infarct and nuclear magnetic resonance. A review of sixty cases. Eur Neurol. 1990; 30:47-51.