A Modified episc culture condition containing a GSK3 inhibitor can support germline-competent pluripotency in mice

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Tsukiyama, Tomoyuki ^a,b   Ohinata, Yasuhide ^a,b,c  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b RIKEN Center for Biosystems Dynamics Research   (Japan)

^c UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; CHIR 99021; ENZYME INHIBITOR; FIBROBLAST GROWTH FACTOR 2; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; 6 [[2 [[4 (2,4 DICHLOROPHENYL) 5 (4 METHYL 1H IMIDAZOL 2 YL) 2 PYRIMIDINYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; ORGANIC CATION TRANSPORTER 3;

ANIMAL CELL; ARTICLE; BLASTOCYST; CHIMERA; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; EPIBLAST STEM CELL; GERMLINE STEM CELL; IN VIVO STUDY; INTERMEDIATE PLURIPOTENT STEM CELL; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; STEM CELL; STEM CELL CULTURE; TERATOMA; WNT SIGNALING PATHWAY; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CULTURE MEDIUM; FIBROBLAST;

EID: 84899687378     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095329.g001     Document Type: Article

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