The Use of Mouse Models of Breast Cancer and Quantitative Image Analysis to Evaluate Hormone Receptor Antigenicity after Microwave-assisted Formalin Fixation

Journal of Histochemistry and Cytochemistry

Volumn 62, Issue 5, 2014, Pages 319-334

  Engelberg, Jesse A ^a   Giberson, Richard T ^b   Young, Lawrence J T ^a   Hubbard, Neil E ^a   Cardiff, Robert D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Ted Pella Inc   (United States)

Author keywords

antigenicity; breast cancer; formalin; microwave; model system; mouse; quantitative image analysis

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; FORMALDEHYDE; KI 67 ANTIGEN; PROGESTERONE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGENICITY; ARTICLE; BREAST CANCER; CANCER MODEL; CANCER PROGNOSIS; CELL DENSITY; CONTROLLED STUDY; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; KOLMOGOROV SMIRNOV TEST; MICROWAVE RADIATION; MOUSE; NONHUMAN; PATHOLOGIST; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; STAINING;

ANTIGENICITY; BREAST CANCER; FORMALIN; MICROWAVE; MODEL SYSTEM; MOUSE; QUANTITATIVE IMAGE ANALYSIS;

ALGORITHMS; ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; FORMALDEHYDE; MICE; MICROWAVES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE;

EID: 84899686082     PISSN: 00221554     EISSN: 15515044     Source Type: Journal    
DOI: 10.1369/0022155414529250     Document Type: Article

References (22)

1. Allred DC,Harvey JM,Berardo M,Clark GM.Prognostic and predictive factors in breast cancer by immunohistochemical analysis.Mod Pathol. 1998;11:155-168.
2. Cardiff RD,Hubbard NE,Engelberg JA,Munn RJ,Miller CH,Walls JE,Chen JQ,Velásquez-García HA,Galvez JJ,Bell KJ,Beckett LA,Li YJ,Borowsky AD.Quantitation of fixative-induced morphologic and antigenic variation in mouse and human breast cancers.Lab Invest. 2013;93:480-497.
3. Chan SR,Vermi W,Luo J,Lucini L,Rickert C,Fowler AM,Lonardi S,Arthur C,Young LJ,Levy DE,Welch MJ,Cardiff RD,Schreiber RD.STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas.Breast Cancer Res. 2012;14:R16.
4. Cuzick J,Dowsett M,Pineda S,Wale C,Salter J,Quinn E,Zabaglo L,Mallon E,Green AR,Ellis IO,Howell A,Buzdar AU,Forbes JF.Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the Genomic Health recurrence score in early breast cancer.J Clin Oncol. 2011;29:4273-4278.
5. Fox CH,Johnson FB,Whiting J,Roller PP.Formaldehyde Fixation.J Histochem Cytochem. 1985;33:845-853.
6. Gagna CE,Kuo H-R,Chan NJ,Mitacek EJ,Spivak A,Pasquariello TD,Balgobin C,Mukhi R,Lambert WC.Novel DNA staining method and processing technique for the quantification of undamaged double-stranded DNA in epidermal tissue sections by PicoGreen probe staining and microspectrophotometry.J Histochem Cytochem. 2007;55:999-1014.
7. Galvez JJ,Giberson RT,Cardiff RD.The role of microwave radiation in reducing formaldehyde fixation times demonstrated in liver.J Histotechnol. 2006;29:113-121.
8. Giberson R,Elliott DMicrowave Techniques and Protocols. Giberson RTDemaree RSJ, ed. Totowa, NJ: Humana Press; 2001:191-208.
9. Goldstein NS,Ferkowicz M,Odish E,Mani A,Hastah F.Minimum formalin fixation time for consistent estrogen receptor immunohistochemical staining of invasive breast carcinoma.Am J Clin Pathol. 2003;120:86-92.
10. Gown AM.Current issues in ER and HER2 testing by IHC in breast cancer.Mod Pathol. 2008;21:S8-S15.
11. Hammond MEH,Hayes DF,Dowsett M,Allred DC,Hagerty KL,Badve S,Fitzgibbons PL,Francis G,Goldstein NS,Hayes M,Hicks DG,Lester S,Love R,Mangu PB,McShane L,Miller K,Osborne CK,Paik S,Perlmutter J,Rhodes A,Sasano H,Schwartz JN,Sweep FC,Taube S,Torlakovic EE,Valenstein P,Viale G,Visscher D,Wheeler T,Williams RB,Wittliff JL,Wolff AC.American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer.J Clin Oncol. 2010;28:2784-2795.
12. Kolmogorov A.Sulla determinazione empirica di una legge di distribuzione.G Ist Ital Attuari. 1933;4:83.
13. Kurosumi M.Immunohistochemical assessment of hormone receptor status using a new scoring system (J-Score) in breast cancer.Breast Cancer. 2007;14:189-193.
14. Leake R,Barnes D,Pinder S,Ellis I,Anderson L,Anderson T,Adamson R,Rhodes T,Miller K,Walker R.Immunohistochemical detection of steroid receptors in breast cancer: a working protocol. UK Receptor Group, UK NEQAS, The Scottish Breast Cancer Pathology Group, and The Receptor and Biomarker Study Group of the EORTC. J Clin Pathol. 2000;53:634-635.
15. McClelland RA,Finlay P,Walker KJ,Nicholson D,Robertson JF,Blamey RW,Nicholson RI.Automated quantitation of immunocytochemically localized estrogen receptors in human breast cancer.Cancer Res. 1990;50:3545-3550.
16. Nofech-Mozes S,Vella ET,Dhesy-Thind S,Hagerty KL,Mangu PB,Temin S,Hanna WM.Systematic review on hormone receptor testing in breast cancer.Appl Immunohistochem Mol Morphol. 2012;20:214-263.
17. Siegel PM,Ryan ED,Cardiff RD,Muller WJ.Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer.EMBO J. 1999;18:2149-2164.
18. Stephens MA.EDF statistics for goodness of fit and some comparisons.J Am Stat Assoc. 1974;69:730-737.
19. Tong LC,Nelson N,Tsourigiannis J,Mulligan AM.The effect of prolonged fixation on the immunohistochemical evaluation of estrogen receptor, progesterone receptor, and HER2 expression in invasive breast cancer: a prospective study. Am J Surg Pathol. 2011;35:545-552.
20. von Wasielewski R,Mengel M,Nolte M,Werner M.Influence of Fixation, Antibody Clones, and Signal Amplification on Steroid Receptor Analysis.Breast J. 1998;4:33-40.
21. Wolff AC,Hammond MEH,Schwartz JN,Hagerty KL,Allred DC,Cote RJ,Dowsett M,Fitzgibbons PL,Hanna WM,Langer A,McShane LM,Paik S,Pegram MD,Perez EA,Press MF,Rhodes A,Sturgeon C,Taube SE,Tubbs R,Vance GH,van de Vijver M,Wheeler TM,Hayes DF.American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.J Clin Oncol. 2007;25:118-145.
22. Yaziji H,Taylor CR,Goldstein NS,Dabbs DJ,Hammond EH,Hewlett B,Floyd AD,Barry TS,Martin AW,Badve S,Baehner F,Cartun RW,Eisen RN,Swanson PE,Hewitt SM,Vyberg M,Hicks DG.Consensus recommendations on estrogen receptor testing in breast cancer by immunohistochemistry.Appl Immunohistochem Mol Morphol. 2008;16:513-520.