메뉴 건너뛰기




Volumn 9, Issue 4, 2014, Pages

The LIM-only protein FHL2 reduces vascular lesion formation involving inhibition of proliferation and migration of smooth muscle cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; FOUR AND HALF LIM DOMAIN PROTEIN 2; KI 67 ANTIGEN; LIM PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; UNCLASSIFIED DRUG; FHL2 PROTEIN, MOUSE; LIM HOMEODOMAIN PROTEIN; MUSCLE PROTEIN; TRANSCRIPTION FACTOR;

EID: 84899677136     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094931     Document Type: Article
Times cited : (19)

References (35)
  • 1
    • 3042588831 scopus 로고    scopus 로고
    • Molecular regulation of vascular smooth muscle cell differentiation in development and disease
    • doi:10.1152/physrev.000412003
    • Owens GK, Kumar MS, Wamhoff BR (2004) Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 84: 767-801. doi:10.1152/physrev.000412003
    • (2004) Physiol Rev , vol.84 , pp. 767-801
    • Owens, G.K.1    Kumar, M.S.2    Wamhoff, B.R.3
  • 2
    • 42149107512 scopus 로고    scopus 로고
    • Role of smooth muscle cells in the initiation and early progression of atherosclerosis
    • doi:10.1161/ATVBAHA.107.159327
    • Doran AC, Meller N, McNamara CA (2008) Role of smooth muscle cells in the initiation and early progression of atherosclerosis. Arterioscler Thromb Vasc Biol 28: 812-819. doi:10.1161/ATVBAHA.107.159327
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 812-819
    • Doran, A.C.1    Meller, N.2    McNamara, C.A.3
  • 3
    • 0028970042 scopus 로고
    • Cell biology of atherosclerosis
    • doi:10.1146/annurev.ph.57.030195.004043
    • Ross R (1995) Cell biology of atherosclerosis. Annu Rev Physiol 57: 791-804. doi:10.1146/annurev.ph.57.030195.004043
    • (1995) Annu Rev Physiol , vol.57 , pp. 791-804
    • Ross, R.1
  • 4
    • 0027241856 scopus 로고
    • The Pathogenesis of Atherosclerosis - A Perspective for the 1990S
    • doi:10.1038/362801a0
    • Ross R (1993) The Pathogenesis of Atherosclerosis - A Perspective for the 1990S. Nature 362: 801-809. doi:10.1038/362801a0
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 5
    • 34547957602 scopus 로고    scopus 로고
    • The pathophysiology and burden of restenosis
    • doi:10.1016/j.amjcard.2007.06.002
    • Weintraub WS (2007) The pathophysiology and burden of restenosis. Am J Cardiol 100: 3K-9K. doi:10.1016/j.amjcard.2007.06.002
    • (2007) Am J Cardiol , vol.100
    • Weintraub, W.S.1
  • 6
    • 33644763311 scopus 로고    scopus 로고
    • In stent restenosis: Bane of the stent era
    • doi:10.1136/jcp.2005.025742
    • Mitra AK, Agrawal DK (2006) In stent restenosis: bane of the stent era. J Clin Pathol 59: 232-239. doi:10.1136/jcp.2005.025742
    • (2006) J Clin Pathol , vol.59 , pp. 232-239
    • Mitra, A.K.1    Agrawal, D.K.2
  • 7
    • 0034163002 scopus 로고    scopus 로고
    • Platelets and restenosis
    • doi:10.1016/S0735-1097(99)00596-3
    • Chandrasekar B, Tanguay JF (2000) Platelets and restenosis. J Am Coll Cardiol 35: 555-562. doi:10.1016/S0735-1097(99)00596-3
    • (2000) J Am Coll Cardiol , vol.35 , pp. 555-562
    • Chandrasekar, B.1    Tanguay, J.F.2
  • 8
    • 0030891415 scopus 로고    scopus 로고
    • Histopathology of in-stent restenosis in patients with peripheral artery disease
    • doi:10.1161/01.CIR.95.8.1998
    • Kearney M, Pieczek A, Haley L, Losordo DW, Andres V, et al. (1997) Histopathology of in-stent restenosis in patients with peripheral artery disease. Circulation 95: 1998-2002. doi:10.1161/01.CIR.95.8.1998
    • (1997) Circulation , vol.95 , pp. 1998-2002
    • Kearney, M.1    Pieczek, A.2    Haley, L.3    Losordo, D.W.4    Andres, V.5
  • 9
    • 32044465297 scopus 로고    scopus 로고
    • The multifunctional roles of the four-and-A-half-LIM only protein FHL2
    • doi:10.1007/s00018-005-5438-z
    • Johannessen M, Moller S, Hansen T, Moens U, Van GM (2006) The multifunctional roles of the four-and-a-half-LIM only protein FHL2. Cell Mol Life Sci 63: 268-284. doi:10.1007/s00018-005-5438-z
    • (2006) Cell Mol Life Sci , vol.63 , pp. 268-284
    • Johannessen, M.1    Moller, S.2    Hansen, T.3    Moens, U.4    Van, G.M.5
  • 10
    • 19944421749 scopus 로고    scopus 로고
    • The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
    • doi:10.1016/j.molcel.2004.11.039
    • Philippar U, Schratt G, Dieterich C, Muller JM, Galgoczy P, et al. (2004) The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF. Mol Cell 16: 867-880. doi:10.1016/j.molcel.2004.11.039
    • (2004) Mol Cell , vol.16 , pp. 867-880
    • Philippar, U.1    Schratt, G.2    Dieterich, C.3    Muller, J.M.4    Galgoczy, P.5
  • 11
    • 84455161605 scopus 로고    scopus 로고
    • FHL2 protein is a novel co-repressor of nuclear receptor Nur77
    • doi:10.1074/jbc.M111.308999
    • Kurakula K, van der Wal E, Geerts D, van Tiel CM, de Vries CJ (2011) FHL2 protein is a novel co-repressor of nuclear receptor Nur77. J Biol Chem 286: 44336-44343. doi:10.1074/jbc.M111.308999
    • (2011) J Biol Chem , vol.286 , pp. 44336-44343
    • Kurakula, K.1    Van Der Wal, E.2    Geerts, D.3    Van Tiel, C.M.4    De Vries, C.J.5
  • 12
    • 67649834590 scopus 로고    scopus 로고
    • The four-anda- half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone
    • doi:10.1074/jbc.M900282200
    • Neuman NA, Ma S, Schnitzler GR, Zhu Y, Lagna G, et al. (2009) The four-anda- half LIM domain protein 2 regulates vascular smooth muscle phenotype and vascular tone. J Biol Chem 284: 13202-13212. doi:10.1074/jbc.M900282200
    • (2009) J Biol Chem , vol.284 , pp. 13202-13212
    • Neuman, N.A.1    Ma, S.2    Schnitzler, G.R.3    Zhu, Y.4    Lagna, G.5
  • 13
    • 1642458404 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes
    • doi:10.1128/MCB.24.3.1081-1095.2004
    • Purcell NH, Darwis D, Bueno OF, Muller JM, Schule R, et al. (2004) Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes. Mol Cell Biol 24: 1081-1095. doi:10.1128/MCB.24.3.1081-1095.2004
    • (2004) Mol Cell Biol , vol.24 , pp. 1081-1095
    • Purcell, N.H.1    Darwis, D.2    Bueno, O.F.3    Muller, J.M.4    Schule, R.5
  • 14
    • 33748439932 scopus 로고    scopus 로고
    • The LIM-only protein FHL2 is a negative regulator of E4F1
    • doi:10.1038/sj.onc.1209567
    • Paul C, Lacroix M, Iankova I, Julien E, Schafer BW, et al. (2006) The LIM-only protein FHL2 is a negative regulator of E4F1. Oncogene 25: 5475-5484. doi:10.1038/sj.onc.1209567
    • (2006) Oncogene , vol.25 , pp. 5475-5484
    • Paul, C.1    Lacroix, M.2    Iankova, I.3    Julien, E.4    Schafer, B.W.5
  • 15
    • 0035811023 scopus 로고    scopus 로고
    • Cardiacspecific LIM protein FHL2 modifies the hypertrophic response to betaadrenergic stimulation
    • doi:10.1161/ 01.CIR.103.22.2731
    • Kong Y, Shelton JM, Rothermel B, Li X, Richardson JA, et al. (2001) Cardiacspecific LIM protein FHL2 modifies the hypertrophic response to betaadrenergic stimulation. Circulation 103: 2731-2738. doi:10.1161/ 01.CIR.103.22.2731
    • (2001) Circulation , vol.103 , pp. 2731-2738
    • Kong, Y.1    Shelton, J.M.2    Rothermel, B.3    Li, X.4    Richardson, J.A.5
  • 16
    • 54049145181 scopus 로고    scopus 로고
    • Regulation of myocardin factor protein stability by the LIM-only protein FHL2
    • doi:10.1152/ajpheart.91421.2007
    • Hinson JS, Medlin MD, Taylor JM, Mack CP (2008) Regulation of myocardin factor protein stability by the LIM-only protein FHL2. Am J Physiol Heart Circ Physiol 295: H1067-H1075. doi:10.1152/ajpheart.91421.2007
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Hinson, J.S.1    Medlin, M.D.2    Taylor, J.M.3    Mack, C.P.4
  • 17
    • 76849085218 scopus 로고    scopus 로고
    • Deletion of the FHL2 gene attenuates the formation of atherosclerotic lesions after a cholesterolenriched diet
    • doi:10.1016/j.lfs.2010.01.007
    • Chu PH, Yeh HI, Wu HH, Hong RC, Shiu TF, et al. (2010) Deletion of the FHL2 gene attenuates the formation of atherosclerotic lesions after a cholesterolenriched diet. Life Sci 86: 365-371. doi:10.1016/j.lfs.2010.01.007
    • (2010) Life Sci , vol.86 , pp. 365-371
    • Chu, P.H.1    Yeh, H.I.2    Wu, H.H.3    Hong, R.C.4    Shiu, T.F.5
  • 18
    • 0031455727 scopus 로고    scopus 로고
    • Remodeling with neointima formation in the mouse carotid artery after cessation of blood flow
    • doi:10.1161/01.ATV.17.10.2238
    • Kumar A, Lindner V (1997) Remodeling with neointima formation in the mouse carotid artery after cessation of blood flow. Arterioscler Thromb Vasc Biol 17: 2238-2244. doi:10.1161/01.ATV.17.10.2238
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2238-2244
    • Kumar, A.1    Lindner, V.2
  • 19
    • 77954783328 scopus 로고    scopus 로고
    • Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels
    • doi:10.1093/cvr/cvq064
    • Bonta PI, Matlung HL, Vos M, Peters SL, Pannekoek H, et al. (2010) Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels. Cardiovasc Res 87: 561-568. doi:10.1093/cvr/cvq064
    • (2010) Cardiovasc Res , vol.87 , pp. 561-568
    • Bonta, P.I.1    Matlung, H.L.2    Vos, M.3    Peters, S.L.4    Pannekoek, H.5
  • 20
    • 0023916169 scopus 로고
    • Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells
    • doi:10.1161/01.RES.62.4.749
    • Geisterfer AA, Peach MJ, Owens GK (1988) Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells. Circ Res 62: 749-756. doi:10.1161/01.RES.62.4.749
    • (1988) Circ Res , vol.62 , pp. 749-756
    • Geisterfer, A.A.1    Peach, M.J.2    Owens, G.K.3
  • 21
    • 34548845557 scopus 로고    scopus 로고
    • Assays for in vitro monitoring of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cell migration
    • doi:10.1038/nprot.2006.434
    • Goncharova EA, Goncharov DA, Krymskaya VP (2006) Assays for in vitro monitoring of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cell migration. Nat Protoc 1: 2933-2939. doi:10.1038/nprot.2006.434
    • (2006) Nat Protoc , vol.1 , pp. 2933-2939
    • Goncharova, E.A.1    Goncharov, D.A.2    Krymskaya, V.P.3
  • 22
    • 77952239323 scopus 로고    scopus 로고
    • Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells
    • doi:10.1038/onc.2010.21
    • Molenaar JJ, Ebus ME, Koster J, Santo E, Geerts D, et al. (2010) Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells. Oncogene 29: 2739-2745. doi:10.1038/onc.2010.21
    • (2010) Oncogene , vol.29 , pp. 2739-2745
    • Molenaar, J.J.1    Ebus, M.E.2    Koster, J.3    Santo, E.4    Geerts, D.5
  • 23
    • 47249128230 scopus 로고    scopus 로고
    • The LIM-only protein FHL2 regulates cyclin D1 expression and cell proliferation
    • doi:10.1074/jbc.M800708200
    • Labalette C, Nouet Y, Sobczak-Thepot J, Armengol C, Levillayer F, et al. (2008) The LIM-only protein FHL2 regulates cyclin D1 expression and cell proliferation. J Biol Chem 283: 15201-15208. doi:10.1074/jbc.M800708200
    • (2008) J Biol Chem , vol.283 , pp. 15201-15208
    • Labalette, C.1    Nouet, Y.2    Sobczak-Thepot, J.3    Armengol, C.4    Levillayer, F.5
  • 24
    • 77956399383 scopus 로고    scopus 로고
    • Four-and-A-Half LIM Domain Protein 2 Is a Novel Regulator of Sphingosine 1- Phosphate Receptor 1 in CCL19-Induced Dendritic Cell Migration
    • doi:10.4049/jimmunol.0903449
    • Konig K, Diehl L, Rommerscheidt-Fuss U, Golletz C, Quast T, et al. (2010) Four-and-a-Half LIM Domain Protein 2 Is a Novel Regulator of Sphingosine 1- Phosphate Receptor 1 in CCL19-Induced Dendritic Cell Migration. J Immunol 185: 1466-1475. doi:10.4049/jimmunol.0903449
    • (2010) J Immunol , vol.185 , pp. 1466-1475
    • Konig, K.1    Diehl, L.2    Rommerscheidt-Fuss, U.3    Golletz, C.4    Quast, T.5
  • 25
    • 34247126014 scopus 로고    scopus 로고
    • Deficiency in the LIM-only protein Fhl2 impairs skin wound healing
    • doi:10.1083/jcb.200606043
    • Wixler V, Hirner S, Muller JM, Gullotti L, Will C, et al. (2007) Deficiency in the LIM-only protein Fhl2 impairs skin wound healing. J Cell Biol 177: 163-172. doi:10.1083/jcb.200606043
    • (2007) J Cell Biol , vol.177 , pp. 163-172
    • Wixler, V.1    Hirner, S.2    Muller, J.M.3    Gullotti, L.4    Will, C.5
  • 26
    • 0032493266 scopus 로고    scopus 로고
    • Cell cycle progression: New therapeutic target for vascular proliferative disease
    • doi:10.1161/01.CIR.98.1.82
    • Braun-Dullaeus RC, Mann MJ, Dzau VJ (1998) Cell cycle progression: new therapeutic target for vascular proliferative disease. Circulation 98: 82-89. doi:10.1161/01.CIR.98.1.82
    • (1998) Circulation , vol.98 , pp. 82-89
    • Braun-Dullaeus, R.C.1    Mann, M.J.2    Dzau, V.J.3
  • 27
    • 0027157897 scopus 로고
    • Proliferative activity in peripheral and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization
    • doi:10.1172/JCI116352
    • Pickering JG, Weir L, Jekanowski J, Kearney MA, Isner JM (1993) Proliferative Activity in Peripheral and Coronary Atherosclerotic Plaque Among Patients Undergoing Percutaneous Revascularization. J Clin Invest 91: 1469-1480. doi:10.1172/JCI116352
    • (1993) J Clin Invest , vol.91 , pp. 1469-1480
    • Pickering, J.G.1    Weir, L.2    Jekanowski, J.3    Kearney, M.A.4    Isner, J.M.5
  • 28
    • 66349112011 scopus 로고    scopus 로고
    • FHL-2 Suppresses VEGF-Induced Phosphatidylinositol 3-Kinase/Akt Activation via InteractionWith Sphingosine Kinase-1
    • doi:10.1161/ATVBAHA.108.178541
    • Hayashi H, Nakagami H, Takami Y, Koriyama H, Mori M, et al. (2009) FHL-2 Suppresses VEGF-Induced Phosphatidylinositol 3-Kinase/Akt Activation via InteractionWith Sphingosine Kinase-1. Arterioscler Thromb Vasc Biol 29: 909- U331. doi:10.1161/ATVBAHA.108.178541
    • (2009) Arterioscler Thromb Vasc Biol , vol.29
    • Hayashi, H.1    Nakagami, H.2    Takami, Y.3    Koriyama, H.4    Mori, M.5
  • 29
    • 84875364441 scopus 로고    scopus 로고
    • Deletion of FHL2 gene impaired ischemia-induced blood flow recovery by modulating circulating proangiogenic cells
    • doi:10.1161/ATVBAHA.112.300318
    • Huang PH, Chen CY, Lin CP, Wang CH, Tsai HY, et al. (2013) Deletion of FHL2 gene impaired ischemia-induced blood flow recovery by modulating circulating proangiogenic cells. Arterioscler Thromb Vasc Biol 33: 709-717. doi:10.1161/ATVBAHA.112.300318
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 709-717
    • Huang, P.H.1    Chen, C.Y.2    Lin, C.P.3    Wang, C.H.4    Tsai, H.Y.5
  • 30
    • 79952735908 scopus 로고    scopus 로고
    • FHL2 exhibits antiproliferative and anti-apoptotic activities in liver cancer cells
    • doi:10.1016/j.canlet.2011.02.001
    • Ng CF, Ng PKS, Lui VWY, Li JL, Chan JYW, et al. (2011) FHL2 exhibits antiproliferative and anti-apoptotic activities in liver cancer cells. Cancer Lett 304: 97-106. doi:10.1016/j.canlet.2011.02.001
    • (2011) Cancer Lett , vol.304 , pp. 97-106
    • Ng, C.F.1    Ng, P.K.S.2    Lui, V.W.Y.3    Li, J.L.4    Chan, J.Y.W.5
  • 31
    • 77951730050 scopus 로고    scopus 로고
    • FHL2 suppresses growth and differentiation of the colon cancer cell line HT-29
    • doi:10.3892/or-00000810
    • Amann T, Egle Y, Bosserhoff AK, Hellerbrand C (2010) FHL2 suppresses growth and differentiation of the colon cancer cell line HT-29. Oncol Rep 23: 1669-1674. doi:10.3892/or-00000810
    • (2010) Oncol Rep , vol.23 , pp. 1669-1674
    • Amann, T.1    Egle, Y.2    Bosserhoff, A.K.3    Hellerbrand, C.4
  • 32
    • 33947715935 scopus 로고    scopus 로고
    • Mechanisms of vascular smooth muscle cell migration
    • doi:10.1161/01.RES.0000258492.96097.47
    • Gerthoffer WT (2007) Mechanisms of vascular smooth muscle cell migration. Circ Res 100: 607-621. doi:10.1161/01.RES.0000258492.96097.47
    • (2007) Circ Res , vol.100 , pp. 607-621
    • Gerthoffer, W.T.1
  • 33
    • 0037625636 scopus 로고    scopus 로고
    • Role of JNK, p38, and ERK in platelet-derived growth factor-induced vascular proliferation, migration, and gene expression
    • doi:10.1161/01.ATV.0000066132.32063.F2
    • Zhan Y, Kim S, Izumi Y, Izumiya Y, Nakao T, et al. (2003) Role of JNK, p38, and ERK in platelet-derived growth factor-induced vascular proliferation, migration, and gene expression. Arterioscler Thromb Vasc Biol 23: 795-801. doi:10.1161/01.ATV.0000066132.32063.F2
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 795-801
    • Zhan, Y.1    Kim, S.2    Izumi, Y.3    Izumiya, Y.4    Nakao, T.5
  • 34
    • 0035827724 scopus 로고    scopus 로고
    • Gene transfer of dominant-negative mutants of extracellular signal-regulated kinase and c-Jun NH2-terminal kinase prevents neointimal formation in ballooninjured rat artery
    • doi:10.1161/hh1101.091267
    • Izumi Y, Kim S, Namba M, Yasumoto H, Miyazaki H, et al. (2001) Gene transfer of dominant-negative mutants of extracellular signal-regulated kinase and c-Jun NH2-terminal kinase prevents neointimal formation in ballooninjured rat artery. Circ Res 88: 1120-6. doi:10.1161/hh1101.091267
    • (2001) Circ Res , vol.88 , pp. 1120-1126
    • Izumi, Y.1    Kim, S.2    Namba, M.3    Yasumoto, H.4    Miyazaki, H.5
  • 35
    • 0031892363 scopus 로고    scopus 로고
    • Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase
    • doi:http://dx.doi.org/10.1016/ S0741-5214(98)70298-8
    • Nelson PR, Yamamura S, Mureebe L, Itoh H, Kent KC (1998) Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase. J Vasc Surg 27: 117-125. doi:http://dx.doi.org/10.1016/S0741-5214(98)70298-8
    • (1998) J Vasc Surg , vol.27 , pp. 117-125
    • Nelson, P.R.1    Yamamura, S.2    Mureebe, L.3    Itoh, H.4    Kent, K.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.