메뉴 건너뛰기




Volumn 9, Issue 4, 2014, Pages

Zeaxanthin dipalmitate therapeutically improves hepatic functions in an alcoholic fatty liver disease model through modulating mapk pathway

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2E1; FAT DROPLET; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIVER PROTECTIVE AGENT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ZEAXANTHIN DIPALMITATE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 8 ISOPROSTANE; ALANINE AMINOTRANSFERASE; ALCOHOL; ALCOHOL DEHYDROGENASE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 7; CATALASE; CHOLESTEROL; COPPER ZINC SUPEROXIDE DISMUTASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MALONALDEHYDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN; PROTEIN BCL 2; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

EID: 84899676267     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095214.t001     Document Type: Article
Times cited : (23)

References (32)
  • 1
    • 37649013155 scopus 로고    scopus 로고
    • Prevalence of fatty liver disease and its risk factors in the population of South China
    • Zhou YJ, Li YY, Nie YQ, Ma JX, Lu LG, et al. (2007) Prevalence of fatty liver disease and its risk factors in the population of South China. World J Gastroenterol 13: 6419-6424.
    • (2007) World J Gastroenterol , vol.13 , pp. 6419-6424
    • Zhou, Y.J.1    Li, Y.Y.2    Nie, Y.Q.3    Ma, J.X.4    Lu, L.G.5
  • 4
    • 84880414748 scopus 로고    scopus 로고
    • Alcoholic liver disease: Pathogenesis, management, and novel targets for therapy
    • Orman ES, Odena G, Bataller R (2013) Alcoholic liver disease: pathogenesis, management, and novel targets for therapy. J Gastroenterol Hepatol 28 Suppl 1: 77-84.
    • (2013) J Gastroenterol Hepatol , vol.28 , Issue.SUPPL. 1 , pp. 77-84
    • Orman, E.S.1    Odena, G.2    Bataller, R.3
  • 5
    • 70349312850 scopus 로고    scopus 로고
    • Current experimental perspectives on the clinical progression of alcoholic liver disease
    • Breitkopf K, Nagy LE, Beier JI, Mueller S, Weng H, et al. (2009) Current experimental perspectives on the clinical progression of alcoholic liver disease. Alcohol Clin Exp Res 33: 1647-1655.
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 1647-1655
    • Breitkopf, K.1    Nagy, L.E.2    Beier, J.I.3    Mueller, S.4    Weng, H.5
  • 6
    • 78650993601 scopus 로고    scopus 로고
    • Hepato-protective potential of carotenoid meso-zeaxanthin against paracetamol, CCl4 and ethanol induced toxicity
    • Firdous AP, Sindhu ER, Kuttan R (2011) Hepato-protective potential of carotenoid meso-zeaxanthin against paracetamol, CCl4 and ethanol induced toxicity. Indian J Exp Biol 49: 44-49.
    • (2011) Indian J Exp Biol , vol.49 , pp. 44-49
    • Firdous, A.P.1    Sindhu, E.R.2    Kuttan, R.3
  • 7
    • 0034599893 scopus 로고    scopus 로고
    • Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture
    • DOI 10.1016/S0304-3835(99)00418-8, PII S0304383599004188
    • Kozuki Y, Miura Y, Yagasaki K (2000) Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture. Cancer Lett 151: 111-115. (Pubitemid 30155592)
    • (2000) Cancer Letters , vol.151 , Issue.1 , pp. 111-115
    • Kozuki, Y.1    Miura, Y.2    Yagasaki, K.3
  • 8
    • 67349094962 scopus 로고    scopus 로고
    • Protective effects of the carotenoid zeaxanthin in experimental nonalcoholic steatohepatitis
    • Chamberlain SM, Hall JD, Patel J, Lee JR, Marcus DM, et al. (2009) Protective effects of the carotenoid zeaxanthin in experimental nonalcoholic steatohepatitis. Dig Dis Sci 54: 1460-1464.
    • (2009) Dig Dis Sci , vol.54 , pp. 1460-1464
    • Chamberlain, S.M.1    Hall, J.D.2    Patel, J.3    Lee, J.R.4    Marcus, D.M.5
  • 9
    • 1342306726 scopus 로고    scopus 로고
    • The role of carotenoids in the prevention of human pathologies
    • DOI 10.1016/j.biopha.2003.12.006
    • Tapiero H, Townsend DM, Tew KD (2004) The role of carotenoids in the prevention of human pathologies. Biomed Pharmacother 58: 100-110. (Pubitemid 38264535)
    • (2004) Biomedicine and Pharmacotherapy , vol.58 , Issue.2 , pp. 100-110
    • Tapiero, H.1    Townsend, D.M.2    Tew, K.D.3
  • 10
    • 84883037365 scopus 로고    scopus 로고
    • Lycium barbarum polysaccharides protect rat liver from non-alcoholic steatohepatitisinduced injury
    • Xiao J, Liong EC, Ching YP, Chang RC, Fung ML, et al. (2013) Lycium barbarum polysaccharides protect rat liver from non-alcoholic steatohepatitisinduced injury. Nutr Diabetes 3: e81.
    • (2013) Nutr Diabetes , vol.3
    • Xiao, J.1    Liong, E.C.2    Ching, Y.P.3    Chang, R.C.4    Fung, M.L.5
  • 11
    • 84856016199 scopus 로고    scopus 로고
    • Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation
    • Xiao J, Liong EC, Ching YP, Chang RC, So KF, et al. (2012) Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation. J Ethnopharmacol 139: 462-470.
    • (2012) J Ethnopharmacol , vol.139 , pp. 462-470
    • Xiao, J.1    Liong, E.C.2    Ching, Y.P.3    Chang, R.C.4    So, K.F.5
  • 14
    • 0000727232 scopus 로고    scopus 로고
    • Antihepatotoxic zeaxanthins from the fruits of Lycium chinense
    • Kim SY, Kim HP, Huh H, Kim YC (1997) Antihepatotoxic zeaxanthins from the fruits ofLycium chinense. Arch Pharm Res 20: 529-532. (Pubitemid 127697214)
    • (1997) Archives of Pharmacal Research , vol.20 , Issue.6 , pp. 529-532
    • Kim, S.Y.1    Kim, H.P.2    Huh, H.3    Kim, Y.C.4
  • 15
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: Minimum information for publication of quantitative real-time PCR experiments
    • Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, et al. (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55: 611-622.
    • (2009) Clin Chem , vol.55 , pp. 611-622
    • Bustin, S.A.1    Benes, V.2    Garson, J.A.3    Hellemans, J.4    Huggett, J.5
  • 16
    • 67651158824 scopus 로고    scopus 로고
    • Role of oxidative stress in alcohol-induced liver injury
    • Cederbaum AI, Lu Y, Wu D (2009) Role of oxidative stress in alcohol-induced liver injury. Arch Toxicol 83: 519-548.
    • (2009) Arch Toxicol , vol.83 , pp. 519-548
    • Cederbaum, A.I.1    Lu, Y.2    Wu, D.3
  • 17
    • 39149123560 scopus 로고    scopus 로고
    • CYP2E1 and oxidative liver injury by alcohol
    • Lu Y, Cederbaum AI (2008) CYP2E1 and oxidative liver injury by alcohol. Free Radic Biol Med 44: 723-738.
    • (2008) Free Radic Biol Med , vol.44 , pp. 723-738
    • Lu, Y.1    Cederbaum, A.I.2
  • 18
    • 84872674658 scopus 로고    scopus 로고
    • Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model
    • Xiao J, Ching YP, Liong EC, Nanji AA, Fung ML, et al. (2013) Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model. Eur J Nutr 52: 179-191.
    • (2013) Eur J Nutr , vol.52 , pp. 179-191
    • Xiao, J.1    Ching, Y.P.2    Liong, E.C.3    Nanji, A.A.4    Fung, M.L.5
  • 19
    • 0032562682 scopus 로고    scopus 로고
    • The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway
    • DOI 10.1074/jbc.273.17.10792
    • Berra E, Diaz-Meco MT, Moscat J (1998) The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway. J Biol Chem 273: 10792-10797. (Pubitemid 28227697)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.17 , pp. 10792-10797
    • Berra, E.1    Diaz-Meco, M.T.2    Moscat, J.3
  • 21
    • 79953107888 scopus 로고    scopus 로고
    • The effect of Lycium barbarum polysaccharide on alcohol-induced oxidative stress in rats
    • Cheng D, Kong H (2011) The effect of Lycium barbarum polysaccharide on alcohol-induced oxidative stress in rats. Molecules 16: 2542-2550.
    • (2011) Molecules , vol.16 , pp. 2542-2550
    • Cheng, D.1    Kong, H.2
  • 22
    • 79551557055 scopus 로고    scopus 로고
    • Resveratrol and liver disease: From bench to bedside and community
    • Bishayee A, Darvesh AS, Politis T, McGory R (2010) Resveratrol and liver disease: from bench to bedside and community. Liver Int 30: 1103-1114.
    • (2010) Liver Int , vol.30 , pp. 1103-1114
    • Bishayee, A.1    Darvesh, A.S.2    Politis, T.3    McGory, R.4
  • 23
    • 84871636895 scopus 로고    scopus 로고
    • Green tea extract (Camellia sinensis) fermented by Lactobacillus fermentum attenuates alcohol-induced liver damage
    • Park JH, Kim Y, Kim SH (2012) Green tea extract (Camellia sinensis) fermented by Lactobacillus fermentum attenuates alcohol-induced liver damage. Biosci Biotechnol Biochem 76: 2294-2300.
    • (2012) Biosci Biotechnol Biochem , vol.76 , pp. 2294-2300
    • Park, J.H.1    Kim, Y.2    Kim, S.H.3
  • 24
    • 33847011682 scopus 로고    scopus 로고
    • Protective effects of silymarin, a milk thistle (Silybium marianum) derivative on ethanol-induced oxidative stress in liver
    • Das SK, Vasudevan DM (2006) Protective effects of silymarin, a milk thistle (Silybium marianum) derivative on ethanol-induced oxidative stress in liver. Indian J Biochem Biophys 43: 306-311.
    • (2006) Indian J Biochem Biophys , vol.43 , pp. 306-311
    • Das, S.K.1    Vasudevan, D.M.2
  • 25
    • 0037668277 scopus 로고    scopus 로고
    • Evaluation of abnormal liver function tests
    • DOI 10.1136/pmj.79.932.307
    • Limdi JK, Hyde GM (2003) Evaluation of abnormal liver function tests. Postgrad Med J 79: 307-312. (Pubitemid 36819456)
    • (2003) Postgraduate Medical Journal , vol.79 , Issue.932 , pp. 307-312
    • Limdi, J.K.1    Hyde, G.M.2
  • 26
    • 84856957894 scopus 로고    scopus 로고
    • Inflammasomemediated dysbiosis regulates progression of NAFLD and obesity
    • Henao-Mejia J, Elinav E, Jin C, Hao L, Mehal WZ, et al. (2012) Inflammasomemediated dysbiosis regulates progression of NAFLD and obesity. Nature 482: 179-185.
    • (2012) Nature , vol.482 , pp. 179-185
    • Henao-Mejia, J.1    Elinav, E.2    Jin, C.3    Hao, L.4    Mehal, W.Z.5
  • 27
    • 16544368662 scopus 로고    scopus 로고
    • Endotoxin and kupffer cell activation in alcoholic liver disease
    • Wheeler MD (2003) Endotoxin and Kupffer cell activation in alcoholic liver disease. Alcohol Res Health 27: 300-306. (Pubitemid 40685569)
    • (2003) Alcohol Research and Health , vol.27 , Issue.4 , pp. 300-306
    • Wheeler, M.D.1
  • 29
    • 77957123293 scopus 로고    scopus 로고
    • Chronic alcoholinduced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice
    • Lu Y, Wu D, Wang X, Ward SC, Cederbaum AI (2010) Chronic alcoholinduced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice. Free Radic Biol Med 49: 1406-1416.
    • (2010) Free Radic Biol Med , vol.49 , pp. 1406-1416
    • Lu, Y.1    Wu, D.2    Wang, X.3    Ward, S.C.4    Cederbaum, A.I.5
  • 30
    • 84870054252 scopus 로고    scopus 로고
    • A specific combination of zeaxanthin, spermidine and rutin prevents apoptosis in human dermal papilla cells
    • Carelli S, Hebda DM, Traversa MV, Messaggio F, Giuliani G, et al. (2012) A specific combination of zeaxanthin, spermidine and rutin prevents apoptosis in human dermal papilla cells. Exp Dermatol 21: 953-955.
    • (2012) Exp Dermatol , vol.21 , pp. 953-955
    • Carelli, S.1    Hebda, D.M.2    Traversa, M.V.3    Messaggio, F.4    Giuliani, G.5
  • 31
    • 44749092972 scopus 로고    scopus 로고
    • Determination of carotenoids and their esters in fruits of Lycium barbarum Linnaeus by HPLCDAD- APCI-MS
    • Inbaraj BS, Lu H, Hung CF, Wu WB, Lin CL, et al. (2008) Determination of carotenoids and their esters in fruits of Lycium barbarum Linnaeus by HPLCDAD- APCI-MS. J Pharm Biomed Anal 47: 812-818.
    • (2008) J Pharm Biomed Anal , vol.47 , pp. 812-818
    • Inbaraj, B.S.1    Lu, H.2    Hung, C.F.3    Wu, W.B.4    Lin, C.L.5
  • 32
    • 84884721349 scopus 로고    scopus 로고
    • Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway
    • Li Y, Gao C, Shi Y, Tang Y, Liu L, et al (2013) Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway.
    • (2013) Toxicol Appl Pharmacol , vol.273 , pp. 53-58
    • Li, Y.1    Gao, C.2    Shi, Y.3    Tang, Y.4    Liu, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.