메뉴 건너뛰기




Volumn 3, Issue 5, 2014, Pages 620-631

Intrastriatal transplantation of adenovirus-generated induced pluripotent stem cells for treating neuropathological and functional deficits in a rodent model of Huntington's disease

Author keywords

3 Nitropropionic acid; Adenovirus; Huntington's disease; iPSC; Stem cell; Transplantation

Indexed keywords

3 NITROPROPIONIC ACID;

EID: 84899672278     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2013-0151     Document Type: Article
Times cited : (29)

References (43)
  • 1
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Disease Collaborative Research Group
    • The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993;72:971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 2
    • 38949103036 scopus 로고    scopus 로고
    • Excitotoxic neuronal death and the pathogenesis of Huntington's disease
    • Estrada Sánchez AM, Mejía-Toiber J, Massieu L. Excitotoxic neuronal death and the pathogenesis of Huntington's disease. ArchMedRes 2008;39:265-276.
    • (2008) ArchMedRes , vol.39 , pp. 265-276
    • Estrada Sánchez, A.M.1    Mejía-Toiber, J.2    Massieu, L.3
  • 3
    • 70350543879 scopus 로고    scopus 로고
    • Intrabody gene therapy ameliorates motor, cognitive, and neuropathological symptoms in multiple mouse models of Huntington's disease
    • Southwell AL, Ko J, Patterson PH. Intrabody gene therapy ameliorates motor, cognitive, and neuropathological symptoms in multiple mouse models of Huntington's disease. J Neurosci 2009;29:13589-13602.
    • (2009) J Neurosci , vol.29 , pp. 13589-13602
    • Southwell, A.L.1    Ko, J.2    Patterson, P.H.3
  • 4
    • 70449698433 scopus 로고    scopus 로고
    • Neural grafts in Huntington's disease: Viability after 10 years
    • Bachoud-Lévi A-C. Neural grafts in Huntington's disease: Viability after 10 years. Lancet Neurol 2009;8:979-981.
    • (2009) Lancet Neurol , vol.8 , pp. 979-981
    • Bachoud-Lévi, A.-C.1
  • 5
    • 68149168120 scopus 로고    scopus 로고
    • Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration
    • Cicchetti F, Saporta S, HauserRAet al. Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration. Proc Natl Acad Sci USA 2009;106:12483-12488.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 12483-12488
    • Cicchetti, F.1    Saporta, S.2    Hauser, R.A.3
  • 6
    • 48249145755 scopus 로고    scopus 로고
    • Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease
    • Reuter I, Tai YF, Pavese N et al. Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease. J Neurol Neurosurg Psychiatry 2008;79:948-951.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , pp. 948-951
    • Reuter, I.1    Tai, Y.F.2    Pavese, N.3
  • 7
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 8
    • 77953466536 scopus 로고    scopus 로고
    • Nuclear reprogramming to a pluripotent state by three approaches
    • Yamanaka S, BlauHM. Nuclear reprogramming to a pluripotent state by three approaches. Nature 2010;465:704-712.
    • (2010) Nature , vol.465 , pp. 704-712
    • Yamanaka, S.1    Blau, H.M.2
  • 9
    • 34249908901 scopus 로고    scopus 로고
    • In vitroreprogrammingof fibroblasts intoa pluripotent ES-cell-like state
    • WernigM, Meissner A, Foreman R et al. In vitroreprogrammingof fibroblasts intoa pluripotent ES-cell-like state. Nature 2007;448:318-324.
    • (2007) Nature , vol.448 , pp. 318-324
    • Wernig, M.1    Meissner, A.2    Foreman, R.3
  • 10
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • Okita K, Ichisaka T, Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007;448:313-317.
    • (2007) Nature , vol.448 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 11
    • 80052458554 scopus 로고    scopus 로고
    • The role of induced pluripotent stem cells inregenerativemedicine: Neurodegenerativediseases
    • Peng J, Zeng X. The role of induced pluripotent stem cells inregenerativemedicine: Neurodegenerativediseases. StemCell ResTher2011;2:32.
    • (2011) StemCell ResTher , vol.2 , pp. 32
    • Peng, J.1    Zeng, X.2
  • 12
    • 84888008310 scopus 로고    scopus 로고
    • Survival and differentiation of adenovirus-generated induced pluripotent stem cells transplanted into the rat striatum
    • [Epub ahead of print]
    • Fink KD, Rossignol J, Lu M et al. Survival and differentiation of adenovirus-generated induced pluripotent stem cells transplanted into the rat striatum. Cell Transplant 2013 [Epub ahead of print].
    • (2013) Cell Transplant
    • Fink, K.D.1    Rossignol, J.2    Lu, M.3
  • 13
    • 77649215222 scopus 로고    scopus 로고
    • 3-Nitropropionic acid as a tool to study the mechanisms involved in Huntington's disease: Past, present and future
    • Túnez I, Tasset I, Pérez-De La Cruz V et al. 3-Nitropropionic acid as a tool to study the mechanisms involved in Huntington's disease: Past, present and future. Molecules 2010;15:878-916.
    • (2010) Molecules , vol.15 , pp. 878-916
    • Túnez, I.1    Tasset, I.2    Pérez-De La Cruz, V.3
  • 14
    • 0034717594 scopus 로고    scopus 로고
    • Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats
    • Shear DA, Haik KL, Dunbar GL. Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats. Neuroreport 2000;11:1833-1837.
    • (2000) Neuroreport , vol.11 , pp. 1833-1837
    • Shear, D.A.1    Haik, K.L.2    Dunbar, G.L.3
  • 15
    • 78650416363 scopus 로고    scopus 로고
    • Mesenchymal stem cell transplantation and DMEM administration in a 3NP rat model of Huntington's disease:Morphological and behavioral outcomes
    • Rossignol J, Boyer C, Lévèque X et al. Mesenchymal stem cell transplantation and DMEM administration in a 3NP rat model of Huntington's disease:Morphological and behavioral outcomes. Behav Brain Res 2011;217:369-378.
    • (2011) Behav Brain Res , vol.217 , pp. 369-378
    • Rossignol, J.1    Boyer, C.2    Lévèque, X.3
  • 16
    • 0035211142 scopus 로고    scopus 로고
    • Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid
    • El Massioui N, Ouary S, Chéruel F et al. Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid. Exp Neurol 2001;172:172-181.
    • (2001) Exp Neurol , vol.172 , pp. 172-181
    • El Massioui, N.1    Ouary, S.2    Chéruel, F.3
  • 17
    • 0028214436 scopus 로고
    • Huntington's disease, energy, and excitotoxicity
    • Beal MF. Huntington's disease, energy, and excitotoxicity. Neurobiol Aging 1994;15: 275-276.
    • (1994) Neurobiol Aging , vol.15 , pp. 275-276
    • Beal, M.F.1
  • 18
    • 0031914584 scopus 로고    scopus 로고
    • Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat
    • Brouillet E, Guyot MC, Mittoux V et al. Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat. J Neurochem 1998;70:794-805.
    • (1998) J Neurochem , vol.70 , pp. 794-805
    • Brouillet, E.1    Guyot, M.C.2    Mittoux, V.3
  • 19
    • 84894515770 scopus 로고    scopus 로고
    • Transplants of adult mesenchymal and neural stem cells provide neuroprotection and behavioral sparing in a transgenic rat model of Huntington's disease
    • Rossignol J, Fink K, Davis K et al. Transplants of adult mesenchymal and neural stem cells provide neuroprotection and behavioral sparing in a transgenic rat model of Huntington's disease. STEM CELLS 2014;32:500-509.
    • (2014) STEM CELLS , vol.32 , pp. 500-509
    • Rossignol, J.1    Fink, K.2    Davis, K.3
  • 20
    • 65749119942 scopus 로고    scopus 로고
    • Mesenchymal stem cells induce a weak immune response in the rat striatum after allo or xenotransplantation
    • Rossignol J, Boyer C, Thinard R et al. Mesenchymal stem cells induce a weak immune response in the rat striatum after allo or xenotransplantation. J Cell Mol Med 2009;13:2547-2558.
    • (2009) J Cell Mol Med , vol.13 , pp. 2547-2558
    • Rossignol, J.1    Boyer, C.2    Thinard, R.3
  • 22
    • 0026339976 scopus 로고
    • Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator
    • West MJ, Slomianka L, Gundersen HJ. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat Rec 1991;231:482-497.
    • (1991) Anat Rec , vol.231 , pp. 482-497
    • West, M.J.1    Slomianka, L.2    Gundersen, H.J.3
  • 23
    • 0033935379 scopus 로고    scopus 로고
    • Survival, neuronal differentiation, and fiber outgrowth of propagated human neural precursor grafts in an animal model of Huntington's disease
    • Armstrong RJ, Watts C, Svendsen CN et al. Survival, neuronal differentiation, and fiber outgrowth of propagated human neural precursor grafts in an animal model of Huntington's disease. Cell Transplant 2000;9:55-64.
    • (2000) Cell Transplant , vol.9 , pp. 55-64
    • Armstrong, R.J.1    Watts, C.2    Svendsen, C.N.3
  • 24
    • 33751087210 scopus 로고    scopus 로고
    • Neural cell adhesion molecule L1-transfected embryonic stem cells promote functional recovery after excitotoxic lesion of the mouse striatum
    • Bernreuther C, Dihné M, Johann V et al. Neural cell adhesion molecule L1-transfected embryonic stem cells promote functional recovery after excitotoxic lesion of the mouse striatum. J Neurosci 2006;26:11532-11539.
    • (2006) J Neurosci , vol.26 , pp. 11532-11539
    • Bernreuther, C.1    Dihné, M.2    Johann, V.3
  • 25
    • 0032211289 scopus 로고    scopus 로고
    • Striatal transplantation in a transgenicmousemodel of Huntington'sdisease
    • Dunnett SB, Carter RJ, Watts C et al. Striatal transplantation in a transgenicmousemodel of Huntington'sdisease. ExpNeurol1998;154:31-40.
    • (1998) ExpNeurol , vol.154 , pp. 31-40
    • Dunnett, S.B.1    Carter, R.J.2    Watts, C.3
  • 26
    • 3042721905 scopus 로고    scopus 로고
    • Human neural stem cell transplants improve motor function in a rat model of Huntington's disease
    • McBride JL, Behrstock SP, Chen E-Y et al. Human neural stem cell transplants improve motor function in a rat model of Huntington's disease. J Comp Neurol 2004;475:211-219.
    • (2004) J Comp Neurol , vol.475 , pp. 211-219
    • McBride, J.L.1    Behrstock, S.P.2    Chen, E.-Y.3
  • 27
    • 2342562572 scopus 로고    scopus 로고
    • Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease
    • Ryu JK, Kim J, Cho SJ et al. Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease. Neurobiol Dis 2004;16: 68-77.
    • (2004) Neurobiol Dis , vol.16 , pp. 68-77
    • Ryu, J.K.1    Kim, J.2    Cho, S.J.3
  • 28
    • 34547489963 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived neural precursor transplants attenuate apomorphineinduced rotational behavior in rats with unilateral quinolinic acid lesions
    • Song J, Lee S-T, Kang W et al. Human embryonic stem cell-derived neural precursor transplants attenuate apomorphineinduced rotational behavior in rats with unilateral quinolinic acid lesions. Neurosci Lett 2007;423:58-61.
    • (2007) Neurosci Lett , vol.423 , pp. 58-61
    • Song, J.1    Lee, S.-T.2    Kang, W.3
  • 29
    • 20144381234 scopus 로고    scopus 로고
    • Intravenous administration ofhumanneural stem cells induces functional recovery in Huntington's disease rat model
    • Lee S-T, Chu K, Park J-E et al. Intravenous administration ofhumanneural stem cells induces functional recovery in Huntington's disease rat model. Neurosci Res 2005;52:243-249.
    • (2005) Neurosci Res , vol.52 , pp. 243-249
    • Lee, S.-T.1    Chu, K.2    Park, J.-E.3
  • 30
    • 33845976361 scopus 로고    scopus 로고
    • Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: Optical neuroimage tracking of brain-grafted cells
    • Pineda JR, Rubio N, Akerud P et al. Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: Optical neuroimage tracking of brain-grafted cells. Gene Ther 2007;14:118-128.
    • (2007) Gene Ther , vol.14 , pp. 118-128
    • Pineda, J.R.1    Rubio, N.2    Akerud, P.3
  • 31
    • 33646164883 scopus 로고    scopus 로고
    • Preservation of striatal tissue and behavioral function after neural stem cell transplantation in a rat model of Huntington's disease
    • Roberts TJ, Price J, Williams SCR et al. Preservation of striatal tissue and behavioral function after neural stem cell transplantation in a rat model of Huntington's disease. Neuroscience 2006;139:1187-1199.
    • (2006) Neuroscience , vol.139 , pp. 1187-1199
    • Roberts, T.J.1    Price, J.2    Williams, S.C.R.3
  • 32
    • 84859152259 scopus 로고    scopus 로고
    • Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments
    • Crittenden JR, Graybiel AM. Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments. Front Neuroanat 2011;5:59.
    • (2011) Front Neuroanat , vol.5 , pp. 59
    • Crittenden, J.R.1    Graybiel, A.M.2
  • 33
    • 33847385967 scopus 로고    scopus 로고
    • Time of transplantation and cell preparation determine neural stem cell survival in a mouse model of Huntington's disease
    • Johann V, Schiefer J, Sass C et al. Time of transplantation and cell preparation determine neural stem cell survival in a mouse model of Huntington's disease. Exp Brain Res 2007;177: 458-470.
    • (2007) Exp Brain Res , vol.177 , pp. 458-470
    • Johann, V.1    Schiefer, J.2    Sass, C.3
  • 34
    • 0032952972 scopus 로고    scopus 로고
    • Regulation of the gene encoding tumor necrosis factor alpha (TNF-alpha) in the rat brain and pituitary in response in differentmodels of systemic immune challenge
    • Nadeau S, Rivest S. Regulation of the gene encoding tumor necrosis factor alpha (TNF-alpha) in the rat brain and pituitary in response in differentmodels of systemic immune challenge. J Neuropathol Exp Neurol 1999;58:61-77.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 61-77
    • Nadeau, S.1    Rivest, S.2
  • 35
    • 0032051772 scopus 로고    scopus 로고
    • Chronic administration of quinolinic acid in the rat striatum causes spatial learning deficits in a radial arm water maze task
    • Shear DA, Dong J, Haik-Creguer KL et al. Chronic administration of quinolinic acid in the rat striatum causes spatial learning deficits in a radial arm water maze task. Exp Neurol 1998;150:305-311.
    • (1998) Exp Neurol , vol.150 , pp. 305-311
    • Shear, D.A.1    Dong, J.2    Haik-Creguer, K.L.3
  • 36
    • 77955278434 scopus 로고    scopus 로고
    • Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease
    • Dey ND, Bombard MC, Roland BP et al. Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease. Behav Brain Res 2010;214:193-200.
    • (2010) Behav Brain Res , vol.214 , pp. 193-200
    • Dey, N.D.1    Bombard, M.C.2    Roland, B.P.3
  • 37
    • 33745543727 scopus 로고    scopus 로고
    • Neurotrophic enhancers as therapy for behavioral deficits in rodent models of Huntington's disease: Use of gangliosides, substituted pyrimidines, and mesenchymal stem cells
    • Dunbar GL, Sandstrom MI, Rossignol J et al. Neurotrophic enhancers as therapy for behavioral deficits in rodent models of Huntington's disease: Use of gangliosides, substituted pyrimidines, and mesenchymal stem cells. Behav Cogn Neurosci Rev 2006;5:63-79.
    • (2006) Behav Cogn Neurosci Rev , vol.5 , pp. 63-79
    • Dunbar, G.L.1    Sandstrom, M.I.2    Rossignol, J.3
  • 38
    • 0042527172 scopus 로고    scopus 로고
    • Autologous adult bone marrowstem cell transplantation in an animal modelof Huntington's disease: Behavioral and morphological outcomes
    • Lescaudron L, Unni D, Dunbar GL. Autologous adult bone marrowstem cell transplantation in an animal modelof Huntington's disease: Behavioral and morphological outcomes. Int J Neurosci 2003;113:945-956.
    • (2003) Int J Neurosci , vol.113 , pp. 945-956
    • Lescaudron, L.1    Unni, D.2    Dunbar, G.L.3
  • 39
    • 84862777143 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice
    • Ma L, Hu B, Liu Y et al. Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice. Cell Stem Cell 2012;10:455-464.
    • (2012) Cell Stem Cell , vol.10 , pp. 455-464
    • Ma, L.1    Hu, B.2    Liu, Y.3
  • 40
    • 84876509620 scopus 로고    scopus 로고
    • Comparative analysis of targeted differentiation of human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells reveals variability associated with incomplete transgene silencing in retrovirally derived hiPSC lines
    • Toivonen S, Ojala M, Hyysalo A et al. Comparative analysis of targeted differentiation of human induced pluripotent stem cells (hiPSCs) and human embryonic stem cells reveals variability associated with incomplete transgene silencing in retrovirally derived hiPSC lines. STEM CELLS TRANSL MED 2013;2:83-93.
    • (2013) STEM CELLS TRANSL MED , vol.2 , pp. 83-93
    • Toivonen, S.1    Ojala, M.2    Hyysalo, A.3
  • 41
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • NakagawaM, Koyanagi M, Tanabe K et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008;26:101-106.
    • (2008) Nat Biotechnol , vol.26 , pp. 101-106
    • Nakagawa, M.1    Koyanagi, M.2    Tanabe, K.3
  • 42
    • 79959915591 scopus 로고    scopus 로고
    • Reprogramming induced pluripotent stem cells in the absence of c-Myc for differentiation into hepatocyte-like cells
    • Li H-Y, Chien Y, Chen Y-J et al. Reprogramming induced pluripotent stem cells in the absence of c-Myc for differentiation into hepatocyte-like cells. Biomaterials 2011;32: 5994-6005.
    • (2011) Biomaterials , vol.32 , pp. 5994-6005
    • Li, H.-Y.1    Chien, Y.2    Chen, Y.-J.3
  • 43
    • 84879436499 scopus 로고    scopus 로고
    • Transplantation of induced pluripotent stem cells without C-Myc attenuates retinal ischemia and reperfusion injury in rats
    • Fang I-M, Yang C-M, Yang C-H et al. Transplantation of induced pluripotent stem cells without C-Myc attenuates retinal ischemia and reperfusion injury in rats. Exp Eye Res 2013;113:49-59.
    • (2013) Exp Eye Res , vol.113 , pp. 49-59
    • Fang, I.-M.1    Yang, C.-M.2    Yang, C.-H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.