Transcriptional changes in canine distemper virus-induced demyelinating leukoencephalitis favor a biphasic mode of demyelination

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Ulrich, Reiner ^a,d   Puff, Christina ^a   Wewetzer, Konstantin ^b,d   Kalkuhl, Arno ^c   Deschl, Ulrich ^c   Baumgar̈tner, Wolfgang ^a,d  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c Department of Non Clinical Drug Safety Boehringer Ingelheim Pharma GmbHandCo KG ^*  (Germany)

^d CENTER FOR SYSTEMS NEUROSCIENCE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; MYELIN BASIC PROTEIN; PROTEOLIPID PROTEIN; RIBONUCLEOPROTEIN; GENETIC MARKER; TRANSCRIPTOME;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANINE DISTEMPER VIRUS INDUCED DEMYELINATING LEUKOENCEPHALITIS; CASE CONTROL STUDY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DEMYELINATION; DOG; DOWN REGULATION; EXPRESSED SEQUENCE TAG; FEMALE; GENE ONTOLOGY; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; HUMORAL IMMUNITY; INNATE IMMUNITY; MALE; MICROARRAY ANALYSIS; MOLECULAR PATHOLOGY; MORBILLIVIRUS INFECTION; NONHUMAN; RETROSPECTIVE STUDY; UPREGULATION; VIRUS REPLICATION; ANIMAL; BRAIN; CANINE DISTEMPER; CANINE DISTEMPER MORBILLIVIRUS; DEMYELINATING DISEASE; GENETIC MARKER; GENETICS; GLIA; LEUKOENCEPHALOPATHY; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PHYSIOLOGY; VETERINARY; VIROLOGY;

ANIMALS; BRAIN; DEMYELINATING DISEASES; DISTEMPER; DISTEMPER VIRUS, CANINE; DOGS; DOWN-REGULATION; FEMALE; GENE ONTOLOGY; GENETIC MARKERS; LEUKOENCEPHALOPATHIES; MALE; MOLECULAR SEQUENCE ANNOTATION; NEUROGLIA; TRANSCRIPTOME; UP-REGULATION;

EID: 84899670022     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095917     Document Type: Article

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