Involvement of morbilliviruses in the pathogenesis of demyelinating disease

Reviews in Medical Virology

Volumn 17, Issue 4, 2007, Pages 223-244

  Sips, G J ^a   Chesik, D ^a   Glazenburg, L ^a   Wilschut, J ^a   De Keyser, J ^a   Wilczak, N ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CANINE DISTEMPER ENCEPHALITIS; CANINE DISTEMPER MORBILLIVIRUS; CATTLE PLAGUE VIRUS; CENTRAL NERVOUS SYSTEM DISEASE; DEMYELINATING DISEASE; DOG; DOLPHIN MORBILLIVIRUS; ENCEPHALOMYELITIS; HOST PATHOGEN INTERACTION; HUMAN; MEASLES INCLUSION BODY ENCEPHALITIS; MEASLES VIRUS; MULTIPLE SCLEROSIS; NEUROPATHOLOGY; NONHUMAN; PARAMYXOVIRUS; PESTE DES PETITIS RUMINANT VIRUS; PHOCINE DISTEMPER VIRUS; PORPOISE MORBILLIVIRUS; POSTINFECTION ENCEPHALITIS; REVIEW; SUBACUTE SCLEROSING PANENCEPHALITIS; SYSTEMATIC REVIEW;

ANIMALS; DEMYELINATING DISEASES; ENCEPHALOMYELITIS, ACUTE DISSEMINATED; HUMANS; MORBILLIVIRUS; MORBILLIVIRUS INFECTIONS; PHYLOGENY; SUBACUTE SCLEROSING PANENCEPHALITIS;

EID: 34447509596     PISSN: 10529276     EISSN: None     Source Type: Journal    
DOI: 10.1002/rmv.526     Document Type: Review

References (239)

1. Westover KM, Hughes AL. Molecular evolution of viral fusion and matrix protein genes and phylogenetic relationships among the Paramyxoviridae. Mol Phylogenet Evol 2001; 21: 128-134.
2. Hall AJ. Morbilliviruses in marine mammals. Trends Microbiol 1995; 31: 4-9.
3. Kennedy S. Morbillivirus infections in aquatic mammals. J Comp Pathol 1998; 119: 201-225.
4. Harder TC, Osterhaus ADME. Canine distemper virus-a morbillivirus in search of new hosts? Trends Microbiol 1997; 5: 120-124.
5. Rima BK, Duprex WP. Morbilliviruses and human disease. J Pathol 2006; 208: 199-214.
6. Cattet MR, Duignan PJ, House CA, et al. Antibodies to canine distemper and phocine distemper viruses in polar bears from the Canadian arctic. J Wildl Dis 2004; 40: 338-342.
7. Philippa JD, Leighton FA, Daoust PY, et al. Antibodies to selected pathogens in free-ranging terrestrial carnivores and marine mammals in Canada. Vet Rec 2004; 155: 135-140.
8. Osterhaus A. Catastrophes after crossing species barriers. Philos Trans R Soc Lond B Biol Sci 2001; 356: 791-793.
9. Cosby SL, Duprex WP, Hamill LA, et al. Approaches in the understanding of morbillivirus neurovirulence. J Neurovirol 2002; 2: 85-90.
10. Vandevelde M, Zurbriggen A. Demyelination in canine distemper virus infection: a review. Acta Neuropathol 2005; 109: 56-68.
11. Kennedy S, Smyth JA, Cush PF, et al. Histopathologic and immunocytochemical studies of distemper in seals. Vet Pathol 1989; 26: 97-103.
12. Di Guardo G, Corradi A, Agrimi U, et al. Neuropathological lesions in cetaceans found stranded from 1991 to 1993 on the coasts of Italy. Eur J Vet Pathol 1995; 1: 47-51.
13. Compston A, Coles A. Multiple sclerosis. Lancet 2002; 359: 1221-1231.
14. Cook SD, Blumberg B, Dowling PC. Potential role of paramyxoviruses in multiple sclerosis. Neurol Clin 1986; 4: 303-319.
15. Ohara Y. Multiple sclerosis and measles virus. Jpn Infect Dis 1999; 52: 198-200.
16. Atkins GJ, McQuaid S, Morris-Downes MM, et al. Transient virus infection and multiple sclerosis. Rev Med Virol 2000; 10: 291-303.
17. Cook SD, Rohowsky-Kochan C, Bansil S, et al. Evidence for multiple sclerosis as an infectious disease. Acta Neurol Scand Suppl 1995; 161: 34-42.
18. Stohlman SA, Hinton DR. Viral induced demyelination. Brain Pathol 2001; 11: 92-106.
19. Johnson RT. The virology of demyelinating diseases. Ann Neurol 1994; 36: S54-S60.
20. Keegan BM, Noseworthy JH. Multiple sclerosis. Annu Rev Med 2002; 53: 285-302.
21. Kandel ER, Schwartz JH, Jessel TM. Principles of Neural Science. McGraw-Hill: New York, 2000; 20-21.
22. Monto AS. Interrupting the transmission of respiratory tract infections: theory and practice. Clin Infect Dis 1999; 28: 200-204.
23. Bryce J, Boschi-Pinto C, Shibuya K, et al. WHO estimates of the causes of death in children. Lancet 2005; 365: 1147-1152.
24. Wild TF. Measles vaccines, new developments and immunization strategies. Vaccine 1999; 17: 1726-1729.
25. Fielding AK. Measles as a potential oncolytic virus. Rev Med Virol 2005; 15: 135-142.
26. Norrby E, Salmi AA, Vandvik B, et al. The antibody response to different measles virus antigens under various conditions of immunization. Adv Exp Med Biol 1972; 31: 49-69.
27. Norrby E, Gollmar Y. Identification of measles virus-specific hemolysis-inhibiting antibodies separate from hemagglutination-inhibiting antibodies. Infect Immun 1975; 11: 231-239.
28. Tyrrell DL, Ehrnst A. Transmembrane communication in cells chronically infected with measles virus. J Cell Biol 1979; 81: 396-402.
29. Suryanarayana K, Baczko K, Ter Meulen V, et al. Transcription inhibition and other properties of matrix proteins expressed by M genes cloned from measles virus and diseased human brain tissue. J Virol 1994; 68: 1532-1543.
30. Taylor MJ, Godfrey E, Baczko K, et al. Identification of several different lineages of measles virus. J Gen Virol 1991; 72: 83-88.
31. Rima BK, Earle JA, Baczko K, et al. Sequence divergence of measles virus haemagluttin during natural evolution and adaptation to cell culture. J Gen Virol 1997; 78: 97-106.
32. Rota JS, Hummel KB, Rota PA, et al. Genetic variabality of the glycoprotein genes of current wild-type measles isolates. Virology 1994; 188: 135-142.
33. Rota PA, Bloom AE, Vanchiere JA, et al. Evolution of the nucleoprotein and matrix genes of wild-type strains of measles virus isolated from recent epidemics. Virology 1994; 198: 724-730.
34. Hall WC, Kovatch RM, Herman PH, et al. Pathology of measles in rhesus monkeys. Vet Pathol 1971; 8: 307-319.
35. Kerdiles YM, Sellin CI, Druelle J, et al. Immunosuppression caused by measles virus: role of viral proteins. Rev Med Virol 2006; 16: 49-63.
36. Kerdiles YM, Cherif B, Marie JC, et al. Immunomodulatory properties of morbillivirus nucleoproteins. Viral Immunol 2006; 19: 324-334.
37. Liebert UG. Measles virus infections of the central nervous system. Intervirology 1997; 40: 176-184.
38. Norrby E, Kristensson K. Measles virus in the brain. Brain Res Bull 1997; 44: 213-220.
39. Menge T, Hemmer B, Nessler S, et al. Acute disseminated encephalomyelitis: an update. Arch Neurol 2005; 62: 1673-1680.
40. Leake JA, Albani S, Kao AS, et al. Acute disseminated encephalomyelitis in childhood: epidemiologic, clinical and laboratory features. Pediatr Infect Dis J 2004; 23: 756-764.
41. Murthy SN, Faden HS, Cohen ME, et al. Acute disseminated encephalomyelitis in children. Pediatrics 2002; 110: e21.
42. Hynson JL, Kornberg AJ, Coleman LT, et al. Clinical and neuroradiologic features of acute disseminated encephalomyelitis in children. Neurology 2001; 56: 1308-1312.
43. Tenembaum S, Chamoles N, Fejerman N. Acute disseminated encephalomyelitis: a long-term follow-up study of 84 pediatric patients. Neurology 2002; 59: 1224-1231.
44. Nasr JT, Andriola MR, Coyle PK. ADEM: literature review and case report of acute psychosis presentation. Pediatr Neurol 2000; 22: 8-18.
45. Khong PL, Ho HK, Cheng PW, et al. Childhood acute disseminated encephalomyelitis: the role of brain and spinal cord MRI. Pediatr Radiol 2002; 32: 59-66.
46. Gendelman HE, Wolinsky JS, Johnson RT, et al. Measles encephalomyelitis: lack of evidence of viral invasion of the central nervous system and quantitative study of the nature of demyelination. Ann Neurol 1984; 15: 353-360.
47. Gendelman HE, Pezeshkpour GH, Pressman NJ, et al. A quantitation of myelin-associated glycoprotein and myelin basic protein loss in different demyelinating diseases. Ann Neurol 1985; 18: 324-328.
48. Wegner C. Pathological differences in acute inflammatory demyelinating diseases of the central nervous system. Int MS J 2005; 12: 13-19.
49. Aicardi J, Goutieres F, Arsenio-Nunes ML, et al. Acute measles encephalitis in children with immunosuppression. Pediatrics 1977; 59: 232-239.
50. Hughes I, Jenney MEM, Newton RW, et al. Measles encephalitis during immunosuppressive treatment for acute lymphoblastic leukaemia. Arch Dis Child 1993; 68: 775-778.
51. Mustafa MM, Weitman SD, Winick NJ, et al. Subacute measles encephalitis in the young immunocompromised host: report of two cases diagnosed by polymerase chain reaction and treated with ribavirin and review of the literature. Clin Infect Dis 1993; 16: 654-660.
52. Mawhinney H, Allen IV, Beare JM, et al. Dysgammaglobulinaemia complicated by disseminated measles. Br Med J 1971; 2: 380-381.
53. Valmari P, Lanning M, Tuokko H, et al. Measles virus in the cerebrospinal fluid in postvaccination immunosuppressive measles encephalopathy. Pediatr Infect Dis 1987; 6: 641-649.
54. Bitnun A, Shannon P, Durward A, et al. Measles inclusion-body encephalitis caused by the vaccine strain of measles virus. Clin Infect Dis 1999; 29: 855-861.
55. Freeman AF, Jacobsohn DA, Shulman ST, et al. A new complication of stem cell transplantation: measles inclusion body encephalitis. Pediatrics 2004; 114: 657-660.
56. Takasu T, Mgone JM, Mgone CS, et al. A continuing high incidence of subacute sclerosing panencephalitis (SSPE) in the Eastern Highlands of Papua New Guinea. Epidemiol Infect 2003; 131: 887-898.
57. Fazakerley JK, Walker R. Virus demyelination. J Neurovirol 2003; 9: 148-164.
58. Modlin JF, Jabbour JR, Witte JJ, et al. Epidemiologic studies of measles; measles vaccines and subacute sclerosing panencephalitis. J Pediatrics 1977; 94: 231-236.
59. Modlin JF, Halsey NA, Eddins DL, et al. Epidemiology of subacute sclerosing panencephalitis. J Pediatrics 1979; 94: 231-236.
60. Jabbour JT, Duenas DA, Sever JL, et al. Epidemiology of subacute sclerosing panencephalitis (SSPE). A report of the SSPE registry. J Am Med Assoc 1972; 220: 959-962.
61. Halsey NA, Modlin JF, Jabbour JT, et al. Risk factors in subacute sclerosing panencephalitis: a case-control study. Am J Epidemiol 1980; 111: 415-424.
62. Garg RK. Subacute sclerosing panencephalitis. Postgrad Med J 2002; 78: 63-70.
63. Connolly JH, Allen IV, Hurwitz LJ, et al. Measles virus antibody and antigen in subacute sclerosing panencephalitis. Lancet 1967; 1: 542-544.
64. Dawson J. Cellular inclusions in cerebral lesions of lethargic encephalitis. Am J Pathol 1933; 9: 7-16.
65. Perier O, Vanderhaeghen JJ, Pelc S. Subacute sclerosing panencephalitis. Electron microscopic findings in two cases with inclusion bodies. Acta Neuropathol 1967; 8: 362-380.
66. McQuaid S, Kirk J, Zhou AL, et al. Measles virus infection of cells in perivascular infiltrates in the brain in subacte sclerosing panencephalitis: confirmation by non-radioactive in situ hybridization, immunocytochemistry and electron microscopy. Acta Neuropathol (Berlin) 1993; 85: 154-158.
67. Kirk J, Zhou AL, McQuaid S, et al. Cerebral endothelial cell infection by measles virus in subacute sclerosing panencephalitis: ultrastructural and in situ hybridization evidence. Neuropathol Appl Neurobiol 1991; 17: 289-297.
68. Smith-Jensen T, Burgoon MP, Anthony J, et al. Comparison of immunoglobulin G heavy-chain sequences in MS and SSPE brains reveals an antigen-driven response. Neurology 2000; 54: 1227-1232.
69. Hall WW, Choppin PW. Evidence for lack of synthesis of the M polypeptide of measles virus in brain cells in subacute sclerosing panencephalitis. Virology 1979; 99: 443-447.
70. Khadilkar SV, Patil SG, Kulkarni KS. A study of SSPE: early clinical features. J Pediatr Neurol 2004; 2: 73-77.
71. Simsek E, Ozturk A, Yavuz C, et al. Subacute sclerosing panencephalitis (SSPE) associated with congenital measles infection. Turk J Pediatr 2005; 47: 58-62.
72. Hall WW, Choppin PW. Measles virus proteins in the brain tissue of patients with subacute sclerosing panencephalitis. N Engl J Med 1981; 304: 1152-1155.
73. Cattaneo R, Schmid A, Spielhofer P, et al. Mutated and hypermutated genes of persistent measles viruses which caused lethal human brain diseases. Virology 1989; 173: 415-425.
74. Billeter MA, Cattaneo R, Spielhofer P, et al. Generation and properties of measles virus mutations typically associated with subacute sclerosing panencephalitis. Ann N Y Acad Sci 1994; 724: 367-377.
75. Cattaneo R, Schmid A, Billeter MA, et al. Multiple viral mutations rather than host factors cause defective measles virus gene expression in a subacute sclerosing panencephalitis cell line. J Virol 1988; 62: 1388-1397.
76. Fujinami RS, Oldstone MB. Alterations in expression of measles virus polypeptides by antibody: molecular events in antibody-induced antigenic modulation. J Immunol 1985; 125: 78-85.
77. Rammohan KW, McFarland HF, Bellini WJ, et al. Antibody-mediated modification of encephalitis induced by hamster neurotropic measles virus. J Infect Dis 1981; 147: 546-549.
78. Rammohan KW, McFarland HF, McFarlin DE. Induction of subacute murine measles encephalitis by monoclonal antibody to virus haemagglutinin. Nature 1981; 290: 588-589.
79. Wear DJ, Rapp F. Latent measles virus infection of the hamster central nervous system. J Immunol 1971; 107: 1593-1598.
80. Liebert UG, Schneider-Schaulies SM, Baczko K, et al. Antibody-induced restriction of viral gene expression in measles encephalitis in rats. J Virol 1990; 64: 706-713.
81. Hanninen P, Arstila P, Lang H, et al. Involvement of the central nervous system in acute, uncomplicated measles virus infection. J Clin Microbiol 1980; 11: 610-613.
82. Hickey WF, Hsu BL, Kimura H. T lymphocyte entry into the central nervous system. J Neurosci Res 1990; 28: 254.
83. Griffin DE, Levine B, Tylor W, et al. The role of antibody in recovery from alpha virus encephalitis. Immunol Rev 1997; 159: 155-161.
84. Knopf PM, Harling-Berg CJ, Cserr HF, et al. Antigen-dependent intrathecal synthesis in the normal rat brain: tissue entry and local retention of antigen-specific B cells. J Immunol 1998; 161: 692-701.
85. Haase AT. Pathogenesis of lentivirus infections. Nature 1986; 322: 130-136.
86. Gendelman HE, Gendelman S. Neurological aspects of human immunodeficiency virus infection. In Neuropathogenic Viruses and Immunity, Specter S, Bendinelli M, Friedman H (eds). Plenu Press: New York, 1992; 229-254.
87. Bergsteinsdottir K, Arnadottir S, Torsteinsdottir S, et al. Constitutive and visna virus induced expression of class I and II major histocompatibility complex antigens in the central nervous system of sheep and their role in the pathogenesis of visna lesions. Neuropathol Appl Neurobiol 1998; 24: 224-232.
88. Oldstone MBA, Boskisch VA, Dixon FJ. Subacute sclerosing panencephalitis: destruction of human brain cells by antibody and complement in an autologous system. Clin Immunol Immunopath 1975; 4: 52-58.
89. Ikeda K, Abiyama H, Kondo H, et al. Numerous glial fibrillary tangles in oligodendroglia in cases of subacute sclerosing panencephalitis with neurofibrillary tangles. Neurosci Lett 1995; 194: 133-135.
90. Hofman FM, Hinton DR, Baemayr J, et al. Lymphokines and immunoregulatory molecules in subacute sclerosing panencephalitis. Clin Immunopathol 1991; 58: 331-342.
91. Nagano I, Nakamura S, Yoshioka M, et al. Expression of cytokines in brain lesions in subacute sclerosing panencephalitis (SSPE). Neurology 1994; 44: 710-715.
92. Roeder PL, Taylor WP. Rinderpest. Vet Clin North Am Food Anim Pract 2002; 18: 515-547.
93. Anderson J, Barrett T. Manual of the diagnosis of Rinderpest. FAO Animal Health Manual (1) 1996; 143 pp.
94. Barrett T, Rossiter PB. Rinderpest: the disease and its impact on humans and animals. Adv Virus Res 1999; 53: 89-110.
95. Chamberlain RW, Wamwayi HN, Hockley E, et al. Evidence for different lineages of rinderpest virus reflecting their geographic isolation. J Gen Virol 1993; 74: 2775-2780.
96. Wohlsein P, Wamwayi HM, Trautwein G, et al. Pathomorphological and immunohistochemical findings in cattle experimentally infected with rinderpest virus isolates of different pathogenecity. Vet Microbiol 1995; 44: 141-147.
97. Rey Nores JE, McCullough KC. Rinderpest virus isolates of different virulence may vary in their capacity to infect bovine monocytes and macrophages. J Gen Virol 1997; 78: 1875-1884.
98. Taylor WP. Epidemiology and control of rinderpest. Rev Sci Tech Off Int Epiz 1986; 5: 407-410.
99. Wafula JS, Kariuki DP. A recent outbreak of rinderpest in East Africa. Trop Anim Hlth Prod 1987; 19: 173-176.
100. Wamwayi HM, Kariuki DP, Wafula JS, et al. Observations on rinderpest in Kenya 1986-1989. Rev Sci Tech Off Int Epiz 1992; 11: 769-784.
101. Rossiter P, Wamwayi H, Ndungu E. Rinderpest seroprevalence in wildlife in Kenya and Tanzania 1982-1993. Prev Vet Med 2006; 17: 1-7.
102. Wohlsein PG, Trautwein TC, Harder B, et al. Viral antigen distribution in organs of cattle experimentally infected with rinderpest virus. Vet Pathol 1993; 30: 544-554.
103. Galbraith SE, McQuaid S, Hamill L, et al. Rinderpest and peste des petits ruminants viruses exhibit neurovirulence in mice. J Neurovirol 2002; 8: 45-52.
104. Gibbs EPJ, Taylor WP, Lawman MJP, et al. Classification of peste des petits ruminants virus as the fourth member of the genus Morbillivirus. Intervirology 1979; 11: 268-274.
105. Haffar A, Libeau G, Moussa A, et al. The matrix protein gene sequence analysis reveals close relationship between peste des petits ruminants virus (PPRV) and dolphin morbillivirus. Virus Res 1999; 64: 69-75.
106. Bailey D, Banyard A, Dash P, et al. Full genome sequence of peste des petits ruminants virus, a member of the morbillivirus genus. Virus Res 2005; 110: 119-124.
107. Dhar P, Sreenivasa BP, Barrett T, et al. Recent epidemiology of peste des petits ruminants virus (PPRV). Vet Microbiol 2002; 88: 153-159.
108. Lefevre PC, Diallo A. La peste des petits ruminants. Rev Sci Tech Off Int Epiz 1990; 9: 935-950.
109. Shaila MS, Purushothaman V, Bhavasar D, et al. Peste des petits ruminants virus of sheep in India. Vet Rec 1989; 125: 602.
110. Taylor WP, Diallo A, Gopalkrishna S, et al. Peste des petits ruminants has been widely present in southern India since, if not before, the late 1980s. Prev Vet Med 2002; 52: 1-8.
111. Shaila MS, Shamaki D, Forsyth MA, et al. Geographical distribution and epidemiology of peste des petits ruminants viruses. Virus Res 1996; 43: 149-153.
112. Nanda YP, Chatterjee A, Purohit AK, et al. The isolation of peste des petits ruminants virus from northern India. Vet Microbiol 1996; 51: 207-216.
113. Roeder PL, Obi TU. Recognizing peste des petits ruminants: a field manual. FAO Animal Health Manual (5) 1999; 28 pp.
114. Wamwayi HM, Rossiter PB, Kariuki DP, et al. Peste des petits ruminants antibodies in east Africa. Vet Rec 1995; 136: 199-200.
115. Roeder PL, Abraham G, Kenfe G, et al. Peste des petits ruminants in Ethiopian goats. Trop Anim Hlth Prod 1994; 26: 69-73.
116. Kumar P, Tripathi BN, Sharma AK, et al. Pathological and immunohistochemical study of experimental peste des petits ruminants virus infection in goats. J Vet Med B Infect Dis Vet Public Health 2004; 51: 153-159.
117. Toplu N. Characteristic and non-characteristic pathological findings in peste des petits ruminants (PPR) of sheep in the Ege District of Turkey. J Comp Path 2004; 131: 135-141.
118. Aruni AW, Lalitha PS, Mohan AC, et al. Histopathological study of a natural outbreak of peste des petits ruminants in goats of Tamilnadu. Small Rumin Res 1998; 28: 233-240.
119. Brown CC, Mariner JC, Olander HJ. An immunohistochemical study of the pneumonia caused by peste des petits ruminants virus. Vet Pathol 1991; 28: 166-170.
120. Bundza A, Afshar A, Dukes WD, et al. Experimental peste des petits ruminants (goat plaque) in goats and sheep. Can J Vet Res 1988; 52: 46-52.
121. Appel MJ. Pathogenesis of canine distemper. Am J Vet Res 1969; 30: 1167-1182.
122. Krakowka S, Higgins RJ, Koestner A. Canine distemper virus: review of structural and functional modulations in lymphoid tissues. Am J Vet Res 1980; 41: 284-292.
123. Rudd PA, Cattaneo R, Von Messling V. Canine distemper virus uses both the anterograde and hematogenous pathway for neuroinvasion. J Virol 2006; 80: 9361-9370.
124. Higgins RJ, Krakowka SG, Metzler A, et al. Primary demyelination in experimental canine distemper virus induced encephalomyelitis in gnotobiotic dogs. Sequential immunologic and morphologic findings. Acta Neuropathol 1982; 58: 1-8.
125. Higgins RJ, Krakowka SG, Metzler AE, et al. Experimental canine distemper encephalomyelitis in neonatal gnotobiotic dogs. A sequential ultrastructural study. Acta Neuropathol 1982; 57: 287-295.
126. Summers BA, Greisen HA, Appel MJ. Early events in canine distemper demyelinating encephalomyelitis. Acta Neuropathol 1979; 46: 1-10.
127. Vandevelde M, Zurbriggen A, Higgins RJ, et al. Spread and distribution of viral antigen in nervous canine distemper. Acta Neuropathol 1985; 67: 211-218.
128. Zurbriggen A, Schmid I, Graber H, et al. Oligodendroglial pathology in canine distemper. Acta Neuropathol 1998; 95: 71-77.
129. Mutinelli F, Vandevelde M, Griot C, et al. Astrocytic infection in canine distemper virus-induced demyelination. Acta Neuropathol 1989; 77: 333-335.
130. Blakemore WF, Summers BA, Appel MG. Evidence of oligodendrocyte infection and degeneration in canine distemper encephalomyelitis. Acta Neuropathol 1989; 77: 550-553.
131. Raine CS. On the development of CNS lesions in natural canine distemper encephalomyelitis. J Neurol Sci 1976; 30: 13-28.
132. Summers BA, Appel MJ. Demyelination in canine distemper encephalomyelitis: an ultrastructural analysis. J Neurocytol 1987; 16: 871-881.
133. Wisniewski H, Raine CS, Kay WJ. Observations on viral demyelinating encephalomyelitis. Canine distemper. Lab Invest 1972; 26: 589-599.
134. Zurbriggen A, Yamawaki M, Vandevelde M. Restricted canine distemper virus infection of oligodendrocytes. Lab Invest 1993; 68: 277-284.
135. Glaus TC, Griot C, Richard A, et al. Ultrastructural and biochemical findings in brain cell cultures infected with canine distemper virus. Acta Neuropathol 1990; 80: 59-67.
136. Graber H, Müller C, Vandevelde A, et al. Restricted infection with canine distemper virus leads to down-regulation of myelin gene transcription in cultured oligodendrocytes. Acta Neuropathol 1995; 90: 312-318.
137. Schobesberger M, Zurbriggen A, Summerfield A, et al. Oligodendroglial degeneration in distemper: apoptosis or necrosis? Acta Neuropathol 1999; 97: 179-187.
138. Schobesberger M, Zurbriggen A, Doherr MG, et al. Demyelination precedes oligodendrocyte loss in canine distemper virus-induced encephalitis. Acta Neuropathol 2002; 103: 11-19.
139. Alldinger S, Wunschmann A, Baumgärtner W, et al. Up-regulation of major histocompatibility complex class II antigen expression in the central nervous system of dogs with spontaneous canine distemper encephalitis. Acta Neuropathol 1996; 92: 273-280.
140. Brügger M, Jungi TW, Zurbriggen A, et al. Canine distemper virus increases procoagulant activity of macrophages. Virology 1992; 190: 616-623.
141. Botteron C, Zurbriggen A, Griot C, et al. Canine distemper virus-immune complexes induce bystander degeneration of oligodendrocytes. Acta Neuropathol 1992; 83: 402-407.
142. Griot-Wenk M, Griot C, Pfister H, et al. Antibody-dependent cellular cytotoxicity in antimyelin antibody-induced olgodendroglial damage in vitro. J Neuroimmunol 1991; 33: 145-155.
143. Tipold A, Moore P, Zurbriggen A, et al. Early T-cell response in the central nervous system in canine distemper virus infection. Acta Neuropathol 1999; 97: 45-56.
144. Barben G, Stettler M, Jaggy A, et al. Detection of IgM antibodies against the nucleocapsid protein of canine distemper virus in dog sera using a dot-blot-assay. J Vet Med A 1999; 46: 115-121.
145. Miao Q, Baumgartner W, Failing K, et al. Phase-dependent expression of matrix metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis. Acta Neuropathol 2003; 106: 468-494.
146. Markus S, Failing K, Baumgartner W. Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper lesions. J Neuroimmunol 2002; 125: 30-41.
147. Gröne A, Fonfara S, Baumgartner W. Cell type-dependent cytokine expression after canine distemper virus infection. Viral Immunol 2002; 15: 493-505.
148. Vandevelde M, Fankhauser R, Kristensen F, et al. Immunoglobulins in demyelinating lesions in canine distemper encephalitis. An immunohistological study. Acta Neuropathol 1981; 54: 31-11.
149. Vandevelde M, Kristensen F, Kristensen B, et al. Immunological and pathological findings in demyelinating encephalitis associated with canine distemper virus infection. Acta Neuropathol 1982; 56: 1-8.
150. Vandevelde M, Zurbriggen A, Steck A, et al. Studies on the intrathecal humoral immune response in canine distemper encephalitis. J Neuroimmunol 1986; 11: 41-51.
151. Wunschmann A, Alldinger S, Kremmer E, et al. Identification of CD4 + and CD8 + T cell subsets and b cells in the brain of dogs with acute-, subacute- and chronic-demyelinating distemper encephalitis. Vet Immunol Immunopathol 1999; 67: 101-116.
152. Bürge T, Griot C, Vandevelde M, et al. Antiviral antibodies stimulate production of reactive oxygen species in cultured canine brain cells infected with canine distemper. J Virol 1989; 63: 2790-2797.
153. Griot C, Bürge T, Vandevelde M, et al. Antibody-induced generation of reactive oxygen radicals by brain macrophages in canine distemper encephalitis: a mechanism for bystander demyelination. Acta Neuropathol 1989; 78: 396-403.
154. Griot C, Bürge T, Vandevelde M, et al. Bystander demyelination through antibody induced macrophage activation in canine distemper virus infection. Schweiz Arch Neurol Psychiatr 1989; 140: 39-41.
155. Krakowka S, McCullough B, Koestner A, et al. Myelin-specific autoantibodies associated with central nervous system demyelination in canine distemper virus infection. Infect Immun 1973; 8: 819-827.
156. Cerruti Sola S, Kristensen F, Vandevelde M, et al. Lymphocyte responsiveness to lectin and myelin antigens in canine distemper infection in relation to the development of demyelinating lesions. J Neuroimmunol 1983 4: 77-90.
157. Summers BA, Greisen HA, Appel MJ. Canine distemper and experimental allergic encephalomyelitis in the dog: comparative patterns of demyelination. J Comp Pathol 1984; 94: 575-589.
158. Bollo E, Zurbriggen A, Vandevelde M, et al. Canine distemper virus clearance in chronic inflammatory demyelination. Acta Neuropathol 1986; 72: 69-73.
159. Müller C, Fatzer R, Beck K, et al. Studies on canine distemper virus persistence in the nervous system. Acta Neuropathol 1995; 89: 438-445.
160. Zurbriggen A, Grabber H, Wagner A, et al. Canine distemper persistence in the nervous system is associated with noncytolytic virus spread. J Virol 1995; 69: 1678-1686.
161. Meertens N, Stoffel MH, Cherpillod P, et al. Mechanism of reduction of virus release and cell-cell fusion in persistent canine distemper virus infection. Acta Neuropathol 2003; 106: 486-494.
162. Volterra A, Meldolesi J. Astrocytes, from brain glue to communication elements: the revolution continues. Nature Rev Neurosci 2005; 6: 626-640.
163. Seifert G, Schilling K, Steinhauser C. Astrocyte dysfunction in neurological disorders: a molecular perspective. 2006; 7: 194-206.
164. De Keyser J, Wilczak N, Walter JH et al. Disappearance of beta2-adrenergic receptors on astrocytes in canine distemper encephalitis: possible implications for the pathogenesis of multiple sclerosis. Neuroreport 2001; 12: 191-194.
165. De Keyser J, Wilczak N, Leta R, et al. Astrocytes in multiple sclerosis lack beta-2 adrenergic receptors. Neurology 1999; 53: 1628-1633.
166. Zeinstra E, Te Riele P, Langlois X, et al. Aminergic receptors in astrogliotic plaques from patients with multiple sclerosis. Neurosci Lett 2002; 331: 87-90.
167. Alldinger S, Fonfara S, Kremmer E, et al. Up-regulation of the hyalonurate receptor CD44 in canine distemper demyelinated plaques. Acta Neuropathol 2000; 99:138-146.
168. Zeinstra E, Wilczak N, Streefland C, et al. Astrocytes in chronic active multiple sclerosis plaques express MHC class II molecules. Neuroreport 2000; 11:89-91.
169. De Keyser J, Zeinstra E, Frohman E. Are astrocytes central players in the pathophysiology of multiple sclerosis? Arch Neurol 2003; 60:132-136.
170. De Keyser J, Zeinstra E, Wilczak N. Astrocytic β2-adrenergic receptors and multiple sclerosis. Neurobiol Dis 2003; 15:331-339.
171. De Keyser J, Zeinstra E, Mostert J, et al. β2-Adrenoreceptor involvement in inflammatory demyelination and axonal degradation in multiple sclerosis. Trends Pharmacol Sci 2004; 25:67-71.
172. Kennedy S. Morbillivirus infections in aquatic mammals. J Comp Pathol 2005; 119: 201-225.
173. Osterhaus AD, Vedder EJ. Identification of virus causing recent seal deaths. Nature 1988; 335: 20.
174. Osterhaus A. A morbillivirus causing recent seal deaths. Vaccine 1989; 7: 483-484.
175. Kennedy S, Smyth JA, McCullough SJ, et al. Confirmation of cause of recent seal deaths. Nature 1988; 335: 404.
176. Have P, Nielsen J, Botner A. The seal deaths in Danish waters 1998 2. Virological studies. Acta Vet Scand 1991; 32: 211-219.
177. Kennedy S. A review of the 1988 European seal morbillivirus epizootic. Vet Rec 1990; 127: 563-567.
178. Di Guardo G, Marruchella G, Agrimi U, et al. Morbillivirus infections in aquatic mammals: a brief overview. J Vet Med 2005; 52: 88-93.
179. Rima BK, Curran MD, Kennedy S. Phocine distemper virus, the agent responsible for the 1988 mass mortality of seals. Sci Total Environ 1992; 115: 45-55.
180. Hall AJ, Pomeroy PP, Harwood J. The descriptive epizootiology of phocine distemper in the UK during 1988/1989. Sci Total Environ 1992; 115: 31-44.
181. Hall AJ. Morbilliviruses in marine mammals. Trends Microbiol 1995; 31: 4-9.
182. Heide-Jorgensen MP, Harkonen T, Dietz R, et al. Retrospective of the 1988 European seal epizootic. Dis Aauat Organ 1992; 13: 37-62.
183. Krogsrud J, Evensen O, Holt G, et al. Seal distemper in Norway in 1988 and 1989. Vet Rec 1990; 126: 460-461.
184. Jauniaux T, Boseret G, Desmecht M, et al. Morbillivirus in common seals stranded on the coast of Belgium and northern France. Vet Rec 2001; 148: 587-591.
185. Visser IK, Vedder EJ, Vos HW, et al. Continued presence of phocine distemper virus in the Dutch wadden sea seal population, Vet Rec 1993; 133: 320-322.
186. Duignan PJ, Sadove S, Saliki JT, et al. Phocine distemper in harbour seals (Phoca vitulina) from Long Island, New York. J Wildl Dis 1993; 29: 465-469.
187. Daoust PY, Haines DM, Thorsen J, et al. Phocine distemper in a harp seal (Phoca groenlandica) from the Gulf of St. Lawrence, Canada. J Wildl Dis 1993; 29: 114-117.
188. Ross PS, Visser IK, Breeders HW, et al. Antibodies to phocine distemper virus in Canadian seals. Vet Rec 1992; 127: 563-567.
189. Henderson G, Trudgett A, Lyons C, et al. Demonstration of antibodies in archival sera from Canadian seals reactive with a European isolate of phocine distemper virus. Sci Total Environ 1992; 115: 93-98.
190. De Swart RL, Harder TC, Ross PS, et al. Morbillivirus and morbillivirus diseases of marine mammals. Infect Agents Dis 1995; 4: 125-130.
191. Duignan PJ, Nielsen O, House C, et al. Epizootiology of morbillivirus infection in harp, hooded and ringed seals from the Canadia Arctic and western Atlantic. J Wildl Dis 1997; 33: 7-19.
192. Duignan PJ, Saliki JT, St Aubin DJ, et al. Epizootiology of morbillivirus infection in North American harbour seals (Phoca vitulina) and gray seals (Halichoerus grypus). J Wildl Dis 1995; 31: 491-501.
193. Jensen T, van de Bildt M, Dietz HH, et al. Another phocine distemper outbreak in Europe. Science 2002; 297: 209.
194. Müller G, Wohlsein P, Beineke A, et al. Phocine distemper in German seals 2002. Infect Dis 2004; 10: 723-725.
195. Rijks JM, van De Bildt MW, Jensen T, et al. Phocine distemper outbreak, The Netherlands, 2002. Emerg Infect Dis 2005; 11: 1945-1948.
196. Harkonen T, Dietz R, Reijnders P, et al. The 1988 and 2002 phocine distemper virus epidemics in European harbour seals. Dis Aquat Organ 2006; 68: 115-130.
197. De Koeijer A, Diekmann O, Reijnders P. Modelling the spread of phocine distemper virus among harbour seals. Bull Math Biol 1998; 60: 585-596.
198. Harkonen T, Dietz R, Reijnders P, et al. The 1988 and 2002 phocine distemper virus epidemics in European harbour seals. Dis Aquat Organ 2006; 68: 115-130.
199. Cosby SL, McQuaid S, Duffy N, et al. Characterization of a seal morbillivirus. Nature 1988; 336: 115-116.
200. Orvell C, Sheshberadaran H. Phocine distemper virus is phylogenetically related to canine distemper virus. Vet Rec 1991; 129: 267-269.
201. Harder TC, Moennig V, Greiserwilke I, et al. Analysis of antigenic differences between 16 phocine distemper virus isolates and other morbilliviruses. Arch Virol 1991; 118: 261-268.
202. Blixenkrone-Moller M, Svansson V, Appel M, et al. Antigenic relationships between field isolates of morbilliviruses from different carnivores. Arch Virol 1992; 123: 279-294.
203. Blixenkrone-Moller M, Sharma B, Varsanyi TM, et al. Sequence analysis of the genes encoding the nucleocapsid protein and phosphoprotein (P) of phocid distemper virus, and editing of the P gene transcript. J Gen Virol 1992; 73: 885-893.
204. Curran MD, Rima BK. The genes encoding the phosphoproteins and matrix proteins of phocine distemper virus. J Gen Virol 1992; 73: 1587-1591.
205. Curran MD, O'Lean D, Kennedy S, et al. Molecular characterization of phocine distemper virus-gene order and sequence of the gene encoding the attachment (H) protein. J Gen Virol 1992; 73: 1189-1194.
206. Curran MD, Lu YJ, Rima BK. The fusion protein gene of phocine distemper virus-nucleotide and deduced amino acid sequences and a comparison of morbillivirus fusion proteins. Arch Virol 1992; 126: 159-169.
207. Rima BK, Curran MD, Kennedy S. Phocine distemper virus, the agent responsible for the 1988 mass mortality of seals. Sci Total Environ 1992; 115: 45-55.
208. Sharma B, Norrby E, Blixenkrone-Moller M, et al. The nucleotide and deduced amino acid sequence of the M gene of phocid distemper virus (PDV) -
209. Kovamees J, Blixenkrone-Moller M, Sharma B, et al. The nucleotide sequence and deduced amino acid composition of the haemagglutin and fusion proteins of the morbillivirus phocid distemper virus. J Gen Virol 1991; 72: 2959-2966.
210. Visser IK, van der Heijden RW, van de Bildt MW, et al. Fusion protein gene nucleotide sequence similarities, shared antigenic sites and phylogenetic analysis suggest that phocid distemper virus type 2 and canine distemper virus belong to the same virus entity. J Gen Virol 1993; 74: 1989-1994.
211. Barrett T, Visser IK, Mamaev L, et al. Dolphin and porpoise morbilliviruses are genetically distinct from phocine distemper virus. Virology 1993; 193: 1010-1012.
212. Harder T, Willhaus T, Frey HR, et al. Morbillivirus infections of seals during the 1988 epidemic in the Bay of Heligoland III. Transmission studies of cell culture-propagated phocine distemper virus in harbour seals (Phoca vitulina) and a gray seal (Halichoerus grypus)-clinical, virological and serological results. J Vet Med Ser B 1990; 37: 641-650.
213. Kennedy S, Smyth JA, Cush PF, et al. Viral distemper now found in porpoises. Nature 1988; 336: 21.
214. Kennedy S, Kuiken T, Ross HM, et al. Morbillivirus infection in two common porpoises (Phocoena phocoena) from the coasts of England and Scotland. Vet Rec 1992; 131: 286-290.
215. Visser IKG, van Bressem MF, de Swart RL, et al. Characterization of morbilliviruses isolated from dolphins and porpoises in Europe. J Gen Virol 1993; 74: 631-641.
216. McCullough SJ, McNeilly F, Allan GM, et al. Isolation and characterization of a porpoise morbillivirus. Arch Virol 1991; 118: 247-252.
217. Welsh MJ, Lyons C, Trudgett A, et al. Characteristics of a cetacean morbillivirus isolated from a porpoise (Phocoena phocoena). Arch Virol 1992; 125: 305-311.
218. Domingo M, Ferrer L, Pumarola M, et al. Morbillivirus in dolphins. Nature 1990; 348: 21.
219. Duignan PJ, Geraci JR, Raga JA, et al. Pathology of morbillivirus infection in striped dolphins (Stenella coeruleoalba) from Valencia and Murcia, Spain. Can J Vet Res 1992; 56: 242-248.
220. Di Guardo GU, Agrimi D, Amaddeo M, et al. Morbillivirus infection in a striped dolphin (Stenella coeruleoalba) from the coast of Italy. Vet Rec 1992; 130: 579-580.
221. Blixenkrone-Moller M, Bolt G, Gottschalck E, et al. Comparative analysis of the gene encoding the nucleocapsid protein of dolphin morbillivirus reveals its distant evolutionary relationship to measles virus and ruminant morbillivirus. J Gen Virol 1994; 75: 2829-2834.
222. Bolt G, Blixenkrone-Moller M. Nucleic acid hybridization analyses confirm the presence of a hitherto unknown morbillivirus in Mediterranean dolphins. Vet Microbiol 1994; 41: 363-372.
223. Bolt G, Blixenkrone-Moller M, Gottschalck E, et al. Nucleotide and deduced amino acid sequences of the matrix (M) and fusion (F) protein genes of cetacean morbilliviruses isolated from a porpoise and a dolphin. Virus Res 1994; 34: 291-294.
224. Rima BK, Wishaupt RGA, Welsh MJ, et al. The evolution of morbilliviruses - a comparison of nucleocapsid gene sequences including a porpoise morbillivirus. Vet Microbiol 1995; 44: 127-134.
225. van Bressem MF, Visser IKG, De Swart RL, et al. Dolphin morbillivirus infection in different parts of the Mediterranean Sea. Arch Virol 1995; 129: 235-242.
226. Lipscomb TP, Schulman FY, Moffett D, et al. Morbilliviral disease in atlantic bottlenose dolphins (Tursiops truncatus) from the 1987-1988 Epizootic. J Wildl Dis 1994; 30: 567-571.
227. Schulman FY, Lipscomb TP, Moffett D, et al. Histologic, immunohistochemical and polymerase chain reaction studies of bottlenose dolphins from the 1987-1988 United States Atlantic Coast Epizootic. Vet Pathol 1997; 34: 288-295.
228. Krafft A, Lichy JH, Lipscomb TP, et al. Post mortem diagnosis of morbillivirus infection in bottle-nosed dolphins (Tursiops truncates) in the Atlantic and Gulf of Mexico epizootics by polymerase chain reaction-based assay. J Wildl Dis 1995; 31: 779-785.
229. Taubenberger JK, Tsai M, Krafft AE, et al. Two morbilliviruses implicated in bottlenose dolphin epizootics. Emerg Infect Dis 1996; 2: 213-216.
230. Piza J. Striped dolphin mortality in the Mediterranean. In Proceedings of the Mediterranean Striped Dolphin Mortality International Workshop, Pastor X, Simmonds S (eds). Greenpeace Mediterranean Sea Project: Palma de Mallorca Spain, 1991; 93-103.
231. Kennedy S, Smyth JA, Cush PF, et al. Histopathological and immunocytochemical studies of distemper in harbor porpoises. Vet Pathol 1991; 28: 1-7.
232. Di Guardo G, Agrimi U, Morelli L, et al. Post mortem investigations on cetaceans found stranded on the coasts of Italy between 1990 and 1993. Vet Rec 1995; 136: 439-442.
233. Di Guardo G, Corradi A, Agrimi U, et al. Neuropathological lesions in cetaceans found stranded from 1991 to 1993 on the coasts of Italy. Eur J Vet Pathol 1995; 1: 47-51.
234. Tsur I, Goffmann O, Yakobsen B, et al. Morbillivirus infection in a bottlenose dolphin (Tursiops truncates) from the Mediterranean sea. Eur J Vet Pathol 1997; 2: 83-85.
235. Sindic CJM, Monteyne P, Laterre EC. The intrathecal synthesis of virus-specific oligoclonal IgG in multiple sclerosis. J Neuroimmunol 1994; 54: 75-80.
236. Correale J, de los Milagros Bassani Molinas M. Oligoclonal bands and antibody responses in multiple sclerosis. J Neurol 2002; 249: 375-389.
237. Reiber H, Ungefehr S, Jacobi C. The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis. Mult Scler 1998; 4: 111-117.
238. Scarisbrick IA, Rodrigues M. Hit-Hit and Hit-Run: viruses in the playing field of multiple sclerosis. Curr Neurol Neurosci Rep 2003; 3: 265-271.
239. Mckinley M, O'Loughlin V. Human anatomy. McGraw-Hill: New York; 2006.