메뉴 건너뛰기




Volumn 9, Issue 4, 2014, Pages

Acute liver failure in rats activates glutamine-glutamate cycle but declines antioxidant enzymes to induce oxidative stress in cerebral cortex and cerebellum

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE AMMONIA LIGASE; GLUTAMINASE; THIOACETAMIDE; CATALASE; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; SUPEROXIDE DISMUTASE;

EID: 84899668314     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095855     Document Type: Article
Times cited : (25)

References (38)
  • 1
    • 0036191173 scopus 로고    scopus 로고
    • Hepatic encephalopathy - Definition, nomenclature, diagnosis, and quantification: Final report of the Working Party at the 11th World Congresses of Gastroenterology, Vienna, 1998
    • DOI 10.1053/jhep.2002.31250
    • Ferenci P, Lockwood A, Mullen K, Tarter R, Weissenborn K, et al. (2002) Hepatic encephalopathy - definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology 35: 716-721. (Pubitemid 34183979)
    • (2002) Hepatology , vol.35 , Issue.3 , pp. 716-721
    • Ferenci, P.1    Lockwood, A.2    Mullen, K.3    Tarter, R.4    Weissenborn, K.5    Blei, A.T.6
  • 2
    • 77956647974 scopus 로고    scopus 로고
    • Glutamine as a mediator of ammonia neurotoxicity: A critical appraisal
    • Albrecht J, Zielinska M, Norenberg MD (2010) Glutamine as a mediator of ammonia neurotoxicity: A critical appraisal. Biochem Pharmacol 80: 1303-1308.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1303-1308
    • Albrecht, J.1    Zielinska, M.2    Norenberg, M.D.3
  • 3
    • 0036629585 scopus 로고    scopus 로고
    • Neurobiology of ammonia
    • DOI 10.1016/S0301-0082(02)00019-9, PII S0301008202000199
    • Felipo V, Butterworth RF (2002) Neurobiology of ammonia. Prog Neurobiol 67: 259-279. (Pubitemid 35229984)
    • (2002) Progress in Neurobiology , vol.67 , Issue.4 , pp. 259-279
    • Felipo, V.1    Butterworth, R.F.2
  • 5
    • 0034005901 scopus 로고    scopus 로고
    • Complications of cirrhosis, III: Hepatic encephalopathy
    • Butterworth RF (2000) Complications of cirrhosis, III: hepatic encephalopathy. J Hepatol 32: 171-180.
    • (2000) J Hepatol , vol.32 , pp. 171-180
    • Butterworth, R.F.1
  • 6
    • 73849102776 scopus 로고    scopus 로고
    • Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity
    • Haussinger D, Görg B (2010) Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity. Curr Opin Clin Nutr Metab Care 13: 87-92.
    • (2010) Curr Opin Clin Nutr Metab Care , vol.13 , pp. 87-92
    • Haussinger, D.1    Görg, B.2
  • 7
    • 36948999820 scopus 로고    scopus 로고
    • Acute and chronic hyperammonemia modulate antioxidant enzymes differently in cerebral cortex and cerebellum
    • DOI 10.1007/s11064-007-9422-x
    • Singh S, Koiri RK, Trigun SK (2008) Acute and chronic hyperammonemia modulate antioxidant enzymes differently in cerebral cortex and cerebellum. Neurochem Res 33: 103-113. (Pubitemid 350242797)
    • (2008) Neurochemical Research , vol.33 , Issue.1 , pp. 103-113
    • Singh, S.1    Koiri, R.K.2    Trigun, S.K.3
  • 8
    • 70450217032 scopus 로고    scopus 로고
    • Natural antioxidants: Therapeutic prospects for cancer and neurological diseases
    • Mates JM, Segura JA, Alonso FJ, Marquez J (2009) Natural antioxidants: therapeutic prospects for cancer and neurological diseases. Mini Rev Med Chem 9: 1202-1214.
    • (2009) Mini Rev Med Chem , vol.9 , pp. 1202-1214
    • Mates, J.M.1    Segura, J.A.2    Alonso, F.J.3    Marquez, J.4
  • 9
    • 77957073688 scopus 로고    scopus 로고
    • Astrocyte glutamine synthetase: Importance in hyperammonemic syndromes and potential target for therapy
    • Brusilow SW, Koehler RC, Traystman RJ, Cooper AJL (2010) Astrocyte glutamine synthetase: importance in hyperammonemic syndromes and potential target for therapy. Neurotherapeutics 7: 452-470.
    • (2010) Neurotherapeutics , vol.7 , pp. 452-470
    • Brusilow, S.W.1    Koehler, R.C.2    Traystman, R.J.3    Cooper, A.J.L.4
  • 10
    • 64949114691 scopus 로고    scopus 로고
    • New insights into brain glutaminases: Beyond their role on glutamatergic transmission
    • Marquez J, Tosina M, de la Rosa V, Segura JA, Alonso FJ, et al. (2009) New insights into brain glutaminases: beyond their role on glutamatergic transmission. Neurochem Int 55: 64-70.
    • (2009) Neurochem Int , vol.55 , pp. 64-70
    • Marquez, J.1    Tosina, M.2    De La Rosa, V.3    Segura, J.A.4    Alonso, F.J.5
  • 11
    • 77956393999 scopus 로고    scopus 로고
    • Mechanism, diagnosis and management of hepatic encephalopathy
    • Prakash R, Mullen KD (2010) Mechanism, diagnosis and management of hepatic encephalopathy. Gastroenterol Hepatol 7: 515-525.
    • (2010) Gastroenterol Hepatol , vol.7 , pp. 515-525
    • Prakash, R.1    Mullen, K.D.2
  • 12
    • 0036093019 scopus 로고    scopus 로고
    • Glutamine synthetase in brain: Effect of ammonia
    • Suárez I, Bodega G, Fernández B (2002) Glutamine synthetase in brain: effect of ammonia. Neurochem Int 4: 123-142.
    • (2002) Neurochem Int , vol.4 , pp. 123-142
    • Suárez, I.1    Bodega, G.2    Fernández, B.3
  • 13
    • 33646480226 scopus 로고    scopus 로고
    • Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis
    • Romero-Gomez M, Jover M, Diaz-Gomez D, de Teran LC, Rodrigo R, et al. (2006) Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis. World J Gastroenterol 12: 2406-2411.
    • (2006) World J Gastroenterol , vol.12 , pp. 2406-2411
    • Romero-Gomez, M.1    Jover, M.2    Diaz-Gomez, D.3    De Teran, L.C.4    Rodrigo, R.5
  • 14
    • 77954224523 scopus 로고    scopus 로고
    • Oxidative stress markers in the brain of patients with cirrhosis and hepatic encephalopathy
    • Görg B, Qvartskhava N, Bidmon HJ, Palomero-Gallagher N, Kircheis G, et al. (2010) Oxidative stress markers in the brain of patients with cirrhosis and hepatic encephalopathy. Hepatology 52: 256-265.
    • (2010) Hepatology , vol.52 , pp. 256-265
    • Görg, B.1    Qvartskhava, N.2    Bidmon, H.J.3    Palomero-Gallagher, N.4    Kircheis, G.5
  • 15
    • 33745013111 scopus 로고    scopus 로고
    • Oxidative stress and neurodegeneration: Where are we now?
    • Halliwell B (2006) Oxidative stress and neurodegeneration: where are we now? J Neurochem 97: 1634-1658.
    • (2006) J Neurochem , vol.97 , pp. 1634-1658
    • Halliwell, B.1
  • 17
    • 78049240500 scopus 로고    scopus 로고
    • Activation of neuronal nitric oxide synthase in cerebellum of chronic hepatic encephalopathy rats is associated with up-regulation of NADPH-producing pathway
    • Singh S, Trigun SK (2010) Activation of neuronal nitric oxide synthase in cerebellum of chronic hepatic encephalopathy rats is associated with up-regulation of NADPH-producing pathway. Cerebellum 9: 384-397.
    • (2010) Cerebellum , vol.9 , pp. 384-397
    • Singh, S.1    Trigun, S.K.2
  • 18
    • 0014428865 scopus 로고
    • Estimation of total thiol, protein bound, and non protein sulfhydryl groups in tissue with Ellman's reagent
    • Sedlak J, Raymond HL (1968) Estimation of total thiol, protein bound, and non protein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem 25: 192-205.
    • (1968) Anal Biochem , vol.25 , pp. 192-205
    • Sedlak, J.1    Raymond, H.L.2
  • 20
    • 0022426171 scopus 로고
    • Purification and properties of glutamine synthetase from liver of Squalus acanthias
    • Shankar RA, Anderson PM (1985) Purification and properties of glutamine synthetase from liver of Squalus acanthias. Arch Biochem Biophys 239: 248-259.
    • (1985) Arch Biochem Biophys , vol.239 , pp. 248-259
    • Shankar, R.A.1    Anderson, P.M.2
  • 21
    • 85036409969 scopus 로고    scopus 로고
    • Glutaminase activity of Lactobacillus reuteri KCTC3594 and expression of the activity in other Lactobacillus spp. by introduction of the glutaminase gene
    • Jeon J, Lee H, So J (2009) Glutaminase activity of Lactobacillus reuteri KCTC3594 and expression of the activity in other Lactobacillus spp. by introduction of the glutaminase gene. Afri J Microbiol Res 3: 605-609.
    • (2009) Afri J Microbiol Res , vol.3 , pp. 605-609
    • Jeon, J.1    Lee, H.2    So, J.3
  • 22
    • 4644295671 scopus 로고    scopus 로고
    • Detection of glutathione reductase after electrophoresis on native or sodium dodecyl sulfate polyacrylamide gels
    • Hou WC, Liang HJ, Wang GC, Liu DZ (2004) Detection of glutathione reductase after electrophoresis on native or sodium dodecyl sulfate polyacrylamide gels. Electrophoresis 25: 2926-2931.
    • (2004) Electrophoresis , vol.25 , pp. 2926-2931
    • Hou, W.C.1    Liang, H.J.2    Wang, G.C.3    Liu, D.Z.4
  • 24
    • 70450225736 scopus 로고    scopus 로고
    • Regression of Dalton's lymphoma in vivo via decline in lactate dehydrogenase and induction of apoptosis by a ruthenium(II)- complex containing 4-carboxy-N-ethylbenzamide as ligand
    • Koiri RK, Trigun SK, Mishra L, Pandey K, Dixit D, et al. (2009) Regression of Dalton's lymphoma in vivo via decline in lactate dehydrogenase and induction of apoptosis by a ruthenium(II)- complex containing 4-carboxy-N-ethylbenzamide as ligand. Invest New Drugs 27: 503-516.
    • (2009) Invest New Drugs , vol.27 , pp. 503-516
    • Koiri, R.K.1    Trigun, S.K.2    Mishra, L.3    Pandey, K.4    Dixit, D.5
  • 26
    • 84856434762 scopus 로고    scopus 로고
    • Alterations of blood brain barrier function in hyperammonemia
    • Skowronska M, Albrecht J (2012) Alterations of blood brain barrier function in hyperammonemia. Neurotox Res 21: 236-244.
    • (2012) Neurotox Res , vol.21 , pp. 236-244
    • Skowronska, M.1    Albrecht, J.2
  • 27
    • 85080034819 scopus 로고    scopus 로고
    • Pathogenetic mechanisms of hepatic encephalopathy
    • Haussinger D, Schliess F (2008) Pathogenetic mechanisms of hepatic encephalopathy. Gut 57: 1156-1165.
    • (2008) Gut , vol.57 , pp. 1156-1165
    • Haussinger, D.1    Schliess, F.2
  • 28
    • 33645863470 scopus 로고    scopus 로고
    • Brain regional alterations in the modulation of the glutamate-nitric oxide-cGMP pathway in liver cirrhosis: Role of hyperammonemia and cell types involved
    • Rodrigo R, Felipo V (2006) Brain regional alterations in the modulation of the glutamate-nitric oxide-cGMP pathway in liver cirrhosis: role of hyperammonemia and cell types involved. Neurochem Int 48: 472-477.
    • (2006) Neurochem Int , vol.48 , pp. 472-477
    • Rodrigo, R.1    Felipo, V.2
  • 30
    • 84882648185 scopus 로고    scopus 로고
    • Moderate grade hyperammonemia activates lactate dehydrogenase-4 and 6-phosphofructo-2-kinase to support increased lactate turnover in the brain slices
    • Mehrotra A, Trigun SK (2013) Moderate grade hyperammonemia activates lactate dehydrogenase-4 and 6-phosphofructo-2-kinase to support increased lactate turnover in the brain slices. Mol Cell Biochem 381: 157-161.
    • (2013) Mol Cell Biochem , vol.381 , pp. 157-161
    • Mehrotra, A.1    Trigun, S.K.2
  • 31
    • 84856299837 scopus 로고    scopus 로고
    • Moderate grade hyperammonemia induced concordant activation of antioxidant enzymes is associated with prevention of oxidative stress in the brain slices
    • Mehrotra A, Trigun SK (2012) Moderate grade hyperammonemia induced concordant activation of antioxidant enzymes is associated with prevention of oxidative stress in the brain slices. Neurochem Res 37: 171-181.
    • (2012) Neurochem Res , vol.37 , pp. 171-181
    • Mehrotra, A.1    Trigun, S.K.2
  • 32
    • 0026628303 scopus 로고
    • Electron microscopic study of brain capillaries in cerebral edema from fulminant hepatic failure
    • Kato M, Hughes RD, Keays RT, Williams R (1992) Electron microscopic study of brain capillaries in cerebral edema from fulminant hepatic failure. Hepatology 15: 1060-1066.
    • (1992) Hepatology , vol.15 , pp. 1060-1066
    • Kato, M.1    Hughes, R.D.2    Keays, R.T.3    Williams, R.4
  • 33
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: Structure, function and inhibition
    • DOI 10.1042/0264-6021:3570593
    • Alderton WK, Cooper CE, Knowles RG (2001) Nitric oxide synthases: structure, function and inhibition. Biochem J 357: 593-615. (Pubitemid 32735142)
    • (2001) Biochemical Journal , vol.357 , Issue.3 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 34
  • 36
    • 0034676493 scopus 로고    scopus 로고
    • Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology
    • Mates JM (2000) Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology 153: 83-104.
    • (2000) Toxicology , vol.153 , pp. 83-104
    • Mates, J.M.1
  • 37
    • 0036709597 scopus 로고    scopus 로고
    • Cellular glutathione and thiol metabolism
    • Dickinson DA, Forman HJ (2002) Cellular glutathione and thiol metabolism. Biochem Pharmacol 64: 1019-1026.
    • (2002) Biochem Pharmacol , vol.64 , pp. 1019-1026
    • Dickinson, D.A.1    Forman, H.J.2
  • 38
    • 0034257048 scopus 로고    scopus 로고
    • Elevation of glutathione levels by ammonium ions in primary cultures of rat astrocytes
    • DOI 10.1016/S0197-0186(00)00028-0, PII S0197018600000280
    • Murthy ChRK, Bender AS, Dombro RS, Bai G, Norenberg MD (2000) Elevation of glutathione levels by ammonium ions in primary cultures of rat astrocytes. Neurochem Int 37: 255-268. (Pubitemid 30254158)
    • (2000) Neurochemistry International , vol.37 , Issue.2-3 , pp. 255-268
    • Murthy, C..R.K.1    Bender, A.S.2    Dombro, R.S.3    Bai, G.4    Norenberg, M.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.