Circulating adipocyte fatty acid binding protein is increased in chronic and acute renal dysfunction

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 24, Issue 9, 2014, Pages 1027-1034

  Ebert, T ^a,b   Hopf, L M ^a,b   Wurst, U ^a,b   Bachmann, A ^a   Kralisch, S ^a,b   Lossner U ^a,b   Platz, M ^a,b   Kratzsch, J ^a   Stolzenburg, J U ^a   Dietel, A ^a   Grisk, O ^c   Beige, J ^d   Anders, M ^e,f   Bast, I ^e,f   Kloting N ^b   Bluher M ^a   Stumvoll, M ^a   Fasshauer, M ^a,b  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^c UNIVERSITY OF GREIFSWALD   (Germany)

^d Klinikum St Georg   (Germany)

^e Outpatient Nephrology Care Unit   (Germany)

^f Outpatient Nephrology Care Units   (Germany)

Author keywords

Adipokines; AFABP; AKI; CKD; Elimination

Indexed keywords

ADIPONECTIN; C REACTIVE PROTEIN; CREATININE; CYSTATIN C; FATTY ACID BINDING PROTEIN 4; GLUCOSE; HIGH DENSITY LIPOPROTEIN; INSULIN; INTERLEUKIN 6; LEPTIN; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; UREA; ADIPOCYTOKINE; FABP4 PROTEIN, HUMAN; FATTY ACID BINDING PROTEIN;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; NEPHRECTOMY; NONHUMAN; PRIORITY JOURNAL; RAT; SEVERE RENAL IMPAIRMENT; VERY ELDERLY; ACUTE KIDNEY FAILURE; ADIPOCYTE; ANIMAL; BLOOD; BODY MASS; CHRONIC KIDNEY FAILURE; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; YOUNG ADULT;

ACUTE KIDNEY INJURY; ADIPOCYTES; ADIPOKINES; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BODY MASS INDEX; CREATININE; CROSS-SECTIONAL STUDIES; FATTY ACID-BINDING PROTEINS; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEPHRECTOMY; RATS; RENAL INSUFFICIENCY, CHRONIC; YOUNG ADULT;

EID: 84899666094     PISSN: 09394753     EISSN: 15903729     Source Type: Journal    
DOI: 10.1016/j.numecd.2014.03.006     Document Type: Article

References (30)

1. Fasshauer M., Paschke R., Stumvoll M. Adiponectin, obesity, and cardiovascular disease. Biochimie 2004, 86:779-784.
2. Wallace A.M., McMahon A.D., Packard C.J., Kelly A., Shepherd J., Gaw A., et al. Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS). Circulation 2001, 104:3052-3056.
3. Kralisch S., Fasshauer M. Adipocyte fatty acid binding protein: a novel adipokine involved in the pathogenesis of metabolic and vascular disease?. Diabetologia 2013, 56:10-21.
4. Furuhashi M., Tuncman G., Gorgun C.Z., Makowski L., Atsumi G., Vaillancourt E., et al. Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature 2007, 447:959-965.
5. Hotamisligil G.S., Johnson R.S., Distel R.J., Ellis R., Papaioannou V.E., Spiegelman B.M. Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science 1996, 274:1377-1379.
6. Makowski L., Boord J.B., Maeda K., Babaev V.R., Uysal K.T., Morgan M.A., et al. Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis. Nat Med 2001, 7:699-705.
7. Schlottmann I., Ehrhart-Bornstein M., Wabitsch M., Bornstein S.R., Lamounier-Zepter V. Calcium-dependent release of adipocyte fatty acid binding protein from human adipocytes. Int J Obes 2014, [Internet], [cited 2014 Jan 24]; Available from:. http://www.nature.com/ijo/journal/vaop/ncurrent/full/ijo2013241a.html.
8. Kralisch S., Ebert T., Lossner U., Jessnitzer B., Stumvoll M., Fasshauer M. Adipocyte fatty acid-binding protein is released from adipocytes by a non-conventional mechanism. Int J Obes 2014, [Internet], [cited 2014 Jan 24]; Available from:. http://www.nature.com/ijo/journal/vaop/ncurrent/abs/ijo2013232a.html.
9. Xu A., Wang Y., Xu J.Y., Stejskal D., Tam S., Zhang J., et al. Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome. Clin Chem 2006, 52:405-413.
10. Xu A., Tso A.W.K., Cheung B.M.Y., Wang Y., Wat N.M.S., Fong C.H.Y., et al. Circulating adipocyte-fatty acid binding protein levels predict the development of the metabolic syndrome a 5-year prospective study. Circulation 2007, 115:1537-1543.
11. Park S.E., Rhee E.-J., Lee W.-Y., Kim W.-J., Yoo S.-H., Bae J.-C., et al. The role of serum adipocyte fatty acid-binding protein on the development of metabolic syndrome is independent of pro-inflammatory cytokines. Nutr Metab Cardiovasc Dis 2012, 22:525-532.
12. Yeung D.C.Y., Xu A., Cheung C.W.S., Wat N.M.S., Yau M.H., Fong C.H.Y., et al. Serum adipocyte fatty acid-binding protein levels were independently associated with carotid atherosclerosis. Arterioscler Thromb Vasc Biol 2007, 27:1796-1802.
13. Doi M., Miyoshi T., Hirohata S., Nakamura K., Usui S., Takeda K., et al. Association of increased plasma adipocyte fatty acid-binding protein with coronary artery disease in non-elderly men. Cardiovasc Diabetol 2011, 10:44.
14. Bao Y., Lu Z., Zhou M., Li H., Wang Y., Gao M., et al. Serum levels of adipocyte fatty acid-binding protein are associated with the severity of coronary artery disease in Chinese women. PLoS One 2011, 6:e19115.
15. Cao H., Sekiya M., Ertunc M.E., Burak M.F., Mayers J.R., White A., et al. Adipocyte lipid chaperone aP2 is a secreted adipokine regulating hepatic glucose production. Cell Metab 2013, 17:768-778.
16. Sommer G., Ziegelmeier M., Bachmann A., Kralisch S., Lossner U., Kratzsch J., et al. Serum levels of adipocyte fatty acid-binding protein (AFABP) are increased in chronic haemodialysis (CD). Clin Endocrinol (Oxf) 2008, 69:901-905.
17. Furuhashi M., Ishimura S., Ota H., Hayashi M., Nishitani T., Tanaka M., et al. Serum fatty acid-binding protein 4 is a predictor of cardiovascular events in end-stage renal disease. PLoS One 2011, 6:e27356.
18. Iwamoto M., Miyoshi T., Doi M., Takeda K., Kajiya M., Nosaka K., et al. Elevated serum adipocyte fatty acid-binding protein concentrations are independently associated with renal dysfunction in patients with stable angina pectoris. Cardiovasc Diabetol 2012, 11:26.
19. Yeung D.C.Y., Xu A., Tso A.W.K., Chow W.S., Wat N.M.S., Fong C.H.Y., et al. Circulating levels of adipocyte and epidermal fatty acid-binding proteins in relation to nephropathy staging and macrovascular complications in type 2 diabetic patients. Diabetes Care 2009, 32:132-134.
20. Richter J., Focke D., Ebert T., Kovacs P., Bachmann A., Lössner U., et al. Serum levels of the adipokine progranulin depend on renal function. Diabetes Care 2013, 36:410-414.
21. Levey A.S., Stevens L.A., Schmid C.H., Zhang Y., (Lucy), Castro A.F., Feldman H.I., et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009, 150:604-612.
22. KDIGO KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl 2013, 3:1.
23. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
24. Richter J., Ebert T., Stolzenburg J.-U., Dietel A., Hopf L., Hindricks J., et al. Response to Comment on: Richter et al. Serum Levels of the Adipokine Progranulin Depend on Renal Function. Diabetes Care 2013, 36:410-414. Diabetes Care 2013; 36: e84-e84.
25. Almagor M., Mintz A., Sibirsky O., Durst A. Preoperative and postoperative levels of interleukin-6 in patients with acute appendicitis: comparison between open and laparoscopic appendectomy. Surg Endosc 2005, 19:331-333.
26. Argiles A., Mourad G., Basset N., Axelrud-Cavadore C., Haiech J., Mion C., et al. Acute adaptative changes to unilateral nephrectomy in humans. Kidney Int 1987, 32:714-720.
27. Nielsen S.E., Sugaya T., Hovind P., et al. Urinary liver-type fatty acid-binding protein predicts progression to nephropathy in type 1 diabetic patients. Diabetes Care 2010, 33:1320-1324.
28. Matsushita K., van der Velde M., Astor B.C., et al. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet 2010, 375:2073-2081.
29. von Eynatten M., Breitling L.P., Roos M., et al. Circulating adipocyte fatty acid-binding protein levels and cardiovascular morbidity and mortality in patients with coronary heart disease a 10-year prospective study. Arterioscler Thromb Vasc Biol 2012, 32:2327-2335.
30. Tönjes A., Kralisch S., Lössner U., et al. Metabolic and genetic predictors of circulating adipocyte fatty acid-binding protein. Int J Obes (Lond) 2012, 36:766-773.