Attenuation of collagen induced arthritis via suppression on Th17 response by activating cholinergic anti-inflammatory pathway with nicotine

European Journal of Pharmacology

Volumn 735, Issue 1, 2014, Pages 97-104

  Wu, Shiyao ^a   Luo, Hui ^a   Xiao, Xianzhong ^b   Zhang, Huali ^b   Li, Tong ^a   Zuo, Xiaoxia ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Central South University   (China)

Author keywords

Cholinergic anti inflammatory pathway; Collagen induced arthritis; Nicotine; Rheumatoid arthritis; Th17 cell

Indexed keywords

ANTIINFLAMMATORY AGENT; CYTOKINE; EOSIN; GAMMA INTERFERON; HEMATOXYLIN; INTERLEUKIN 17; INTERLEUKIN 4; NICOTINE; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; GATA3 PROTEIN, MOUSE; RORC PROTEIN, MOUSE; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATORY DISEASE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SPLEEN; SYNOVIUM; TH1 CELL; TH1 TH2 BALANCE; TH17 CELL; TH2 CELL; THERAPY EFFECT; VAGOTOMY; ANIMAL; ANKLE; ARTHRITIS, EXPERIMENTAL; BLOOD; DBA MOUSE; DRUG EFFECTS; IMMUNOLOGY; PATHOLOGY;

ANIMALS; ANKLE JOINT; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; CYTOKINES; GATA3 TRANSCRIPTION FACTOR; MALE; MICE, INBRED DBA; NICOTINE; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; SPLEEN; SYNOVIAL MEMBRANE; T-BOX DOMAIN PROTEINS; TH1 CELLS; TH17 CELLS; TH2 CELLS;

EID: 84899664963     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.04.019     Document Type: Article

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