메뉴 건너뛰기




Volumn 111, Issue 17, 2014, Pages

Brf1 posttranscriptionally regulates pluripotency and differentiation responses downstream of Erk MAP kinase

Author keywords

AU rich element RNA binding proteins; Developmental mechanisms; Developmental signaling pathways; Gene regulation dynamics; Stem cell biology

Indexed keywords

BRF1 PROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEIC ACID BINDING PROTEIN; TRANSCRIPTION FACTOR NANOG; TRISTETRAPROLIN; UNCLASSIFIED DRUG;

EID: 84899652303     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1320873111     Document Type: Article
Times cited : (23)

References (47)
  • 2
    • 84883741725 scopus 로고    scopus 로고
    • The RNA-binding protein repertoire of embryonic stem cells
    • Kwon SC, et al. (2013) The RNA-binding protein repertoire of embryonic stem cells. Nat Struct Mol Biol 20(9):1122-1130.
    • (2013) Nat Struct Mol Biol , vol.20 , Issue.9 , pp. 1122-1130
    • Kwon, S.C.1
  • 3
    • 44449166478 scopus 로고    scopus 로고
    • RNA-binding proteins and posttranscriptional gene regulation
    • Glisovic T, Bachorik JL, Yong J, Dreyfuss G (2008) RNA-binding proteins and posttranscriptional gene regulation. FEBS Lett 582(14):1977-1986.
    • (2008) FEBS Lett , vol.582 , Issue.14 , pp. 1977-1986
    • Glisovic, T.1    Bachorik, J.L.2    Yong, J.3    Dreyfuss, G.4
  • 4
    • 0030909816 scopus 로고    scopus 로고
    • A hierarchy of Hu RNA binding proteins in developing and adult neurons
    • Okano HJ, Darnell RB (1997) A hierarchy of Hu RNA binding proteins in developing and adult neurons. J Neurosci 17(9):3024-3037.
    • (1997) J Neurosci , vol.17 , Issue.9 , pp. 3024-3037
    • Okano, H.J.1    Darnell, R.B.2
  • 5
    • 82155183375 scopus 로고    scopus 로고
    • AU-rich RNA binding proteins in hematopoiesis and leukemogenesis
    • Baou M, Norton JD, Murphy JJ (2011) AU-rich RNA binding proteins in hematopoiesis and leukemogenesis. Blood 118(22):5732-5740.
    • (2011) Blood , vol.118 , Issue.22 , pp. 5732-5740
    • Baou, M.1    Norton, J.D.2    Murphy, J.J.3
  • 6
    • 79958738225 scopus 로고    scopus 로고
    • HuB (elavl2) mRNA is restricted to the germ cells by post-transcriptional mechanisms including stabilisation of the message by DAZL
    • Wiszniak SE, Dredge BK, Jensen KB (2011) HuB (elavl2) mRNA is restricted to the germ cells by post-transcriptional mechanisms including stabilisation of the message by DAZL. PLoS One 6(6):e20773.
    • (2011) PLoS One , vol.6 , Issue.6
    • Wiszniak, S.E.1    Dredge, B.K.2    Jensen, K.B.3
  • 7
    • 80051693551 scopus 로고    scopus 로고
    • The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages
    • Chi MN, et al. (2011) The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages. Mol Biol Cell 22(16): 2875-2885.
    • (2011) Mol Biol Cell , vol.22 , Issue.16 , pp. 2875-2885
    • Chi, M.N.1
  • 8
    • 66349125085 scopus 로고    scopus 로고
    • The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development
    • Katsanou V, et al. (2009) The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development. Mol Cell Biol 29(10):2762-2776.
    • (2009) Mol Cell Biol , vol.29 , Issue.10 , pp. 2762-2776
    • Katsanou, V.1
  • 9
    • 3042714493 scopus 로고    scopus 로고
    • Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family
    • Stumpo DJ, et al. (2004) Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family. Mol Cell Biol 24(14):6445-6455.
    • (2004) Mol Cell Biol , vol.24 , Issue.14 , pp. 6445-6455
    • Stumpo, D.J.1
  • 10
    • 80052203045 scopus 로고    scopus 로고
    • Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells
    • Bourcier C, et al. (2011) Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells. Am J Physiol Cell Physiol 301(3):C609-C618.
    • (2011) Am J Physiol Cell Physiol , vol.301 , Issue.3
    • Bourcier, C.1
  • 11
    • 34047174559 scopus 로고    scopus 로고
    • A module of negative feedback regulators defines growth factor signaling
    • Amit I, et al. (2007) A module of negative feedback regulators defines growth factor signaling. Nat Genet 39(4):503-512.
    • (2007) Nat Genet , vol.39 , Issue.4 , pp. 503-512
    • Amit, I.1
  • 12
    • 77957669746 scopus 로고    scopus 로고
    • The role of FGF/Erk signaling in pluripotent cells
    • Lanner F, Rossant J (2010) The role of FGF/Erk signaling in pluripotent cells. Development 137(20):3351-3360.
    • (2010) Development , vol.137 , Issue.20 , pp. 3351-3360
    • Lanner, F.1    Rossant, J.2
  • 13
    • 78650730724 scopus 로고    scopus 로고
    • The origin and identity of embryonic stem cells
    • Nichols J, Smith A (2011) The origin and identity of embryonic stem cells. Development 138(1):3-8.
    • (2011) Development , vol.138 , Issue.1 , pp. 3-8
    • Nichols, J.1    Smith, A.2
  • 14
    • 33749633094 scopus 로고    scopus 로고
    • The Grb2/Mek pathway represses Nanog in murine embryonic stem cells
    • Hamazaki T, Kehoe SM, Nakano T, Terada N (2006) The Grb2/Mek pathway represses Nanog in murine embryonic stem cells. Mol Cell Biol 26(20):7539-7549.
    • (2006) Mol Cell Biol , vol.26 , Issue.20 , pp. 7539-7549
    • Hamazaki, T.1    Kehoe, S.M.2    Nakano, T.3    Terada, N.4
  • 15
    • 44349170450 scopus 로고    scopus 로고
    • The ground state of embryonic stem cell self-renewal
    • Ying QL, et al. (2008) The ground state of embryonic stem cell self-renewal. Nature 453(7194):519-523.
    • (2008) Nature , vol.453 , Issue.7194 , pp. 519-523
    • Ying, Q.L.1
  • 17
    • 77954939922 scopus 로고    scopus 로고
    • Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia
    • Hodson DJ, et al. (2010) Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia. Nat Immunol 11(8):717-724.
    • (2010) Nat Immunol , vol.11 , Issue.8 , pp. 717-724
    • Hodson, D.J.1
  • 18
    • 1842529308 scopus 로고    scopus 로고
    • Tissue distribution of AU-rich mRNA-binding proteins involved in regulation of mRNA decay
    • Lu JY, Schneider RJ (2004) Tissue distribution of AU-rich mRNA-binding proteins involved in regulation of mRNA decay. J Biol Chem 279(13):12974-12979.
    • (2004) J Biol Chem , vol.279 , Issue.13 , pp. 12974-12979
    • Lu, J.Y.1    Schneider, R.J.2
  • 19
    • 55049088775 scopus 로고    scopus 로고
    • Signalling pathways regulating nucleocytoplasmic shuttling of the mRNA-binding protein HuR
    • Doller A, Pfeilschifter J, Eberhardt W (2008) Signalling pathways regulating nucleocytoplasmic shuttling of the mRNA-binding protein HuR. Cell Signal 20(12):2165-2173.
    • (2008) Cell Signal , vol.20 , Issue.12 , pp. 2165-2173
    • Doller, A.1    Pfeilschifter, J.2    Eberhardt, W.3
  • 20
    • 31144448042 scopus 로고    scopus 로고
    • AU-rich elements and associated factors: Are there unifying principles?
    • Barreau C, Paillard L, Osborne HB (2005) AU-rich elements and associated factors: Are there unifying principles? Nucleic Acids Res 33(22):7138-7150.
    • (2005) Nucleic Acids Res , vol.33 , Issue.22 , pp. 7138-7150
    • Barreau, C.1    Paillard, L.2    Osborne, H.B.3
  • 21
    • 0031573953 scopus 로고    scopus 로고
    • Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny
    • Wilder PJ, et al. (1997) Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny. Dev Biol 192(2): 614-629.
    • (1997) Dev Biol , vol.192 , Issue.2 , pp. 614-629
    • Wilder, P.J.1
  • 22
    • 33746773659 scopus 로고    scopus 로고
    • Dissecting self-renewal in stem cells with RNA interference
    • Ivanova N, et al. (2006) Dissecting self-renewal in stem cells with RNA interference. Nature 442(7102):533-538.
    • (2006) Nature , vol.442 , Issue.7102 , pp. 533-538
    • Ivanova, N.1
  • 23
    • 0031833476 scopus 로고    scopus 로고
    • Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages
    • Nishikawa SI, Nishikawa S, Hirashima M, Matsuyoshi N, Kodama H (1998) Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages. Development 125(9): 1747-1757.
    • (1998) Development , vol.125 , Issue.9 , pp. 1747-1757
    • Nishikawa, S.I.1    Nishikawa, S.2    Hirashima, M.3    Matsuyoshi, N.4    Kodama, H.5
  • 24
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    • Ying QL, Nichols J, Chambers I, Smith A (2003) BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115(3):281-292.
    • (2003) Cell , vol.115 , Issue.3 , pp. 281-292
    • Ying, Q.L.1    Nichols, J.2    Chambers, I.3    Smith, A.4
  • 25
    • 33845275018 scopus 로고    scopus 로고
    • RIP-Chip: The isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts
    • Keene JD, Komisarow JM, Friedersdorf MB (2006) RIP-Chip: The isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts. Nat Protoc 1(1):302-307.
    • (2006) Nat Protoc , vol.1 , Issue.1 , pp. 302-307
    • Keene, J.D.1    Komisarow, J.M.2    Friedersdorf, M.B.3
  • 26
    • 33845431240 scopus 로고    scopus 로고
    • Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTPdeficient fibroblasts
    • Lai WS, Parker JS, Grissom SF, Stumpo DJ, Blackshear PJ (2006) Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTPdeficient fibroblasts. Mol Cell Biol 26(24):9196-9208.
    • (2006) Mol Cell Biol , vol.26 , Issue.24 , pp. 9196-9208
    • Lai, W.S.1    Parker, J.S.2    Grissom, S.F.3    Stumpo, D.J.4    Blackshear, P.J.5
  • 27
    • 3543003469 scopus 로고    scopus 로고
    • The stability of tristetraprolin mRNA is regulated by mitogen-activated protein kinase p38 and by tristetraprolin itself
    • Tchen CR, Brook M, Saklatvala J, Clark AR (2004) The stability of tristetraprolin mRNA is regulated by mitogen-activated protein kinase p38 and by tristetraprolin itself. J Biol Chem 279(31):32393-32400.
    • (2004) J Biol Chem , vol.279 , Issue.31 , pp. 32393-32400
    • Tchen, C.R.1    Brook, M.2    Saklatvala, J.3    Clark, A.R.4
  • 28
    • 0041689753 scopus 로고    scopus 로고
    • Selective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoform
    • Sarkar B, Xi Q, He C, Schneider RJ (2003) Selective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoform. Mol Cell Biol 23(18):6685-6693.
    • (2003) Mol Cell Biol , vol.23 , Issue.18 , pp. 6685-6693
    • Sarkar, B.1    Xi, Q.2    He, C.3    Schneider, R.J.4
  • 29
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • Chambers I, et al. (2003) Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113(5):643-655.
    • (2003) Cell , vol.113 , Issue.5 , pp. 643-655
    • Chambers, I.1
  • 30
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • Mitsui K, et al. (2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113(5):631-642.
    • (2003) Cell , vol.113 , Issue.5 , pp. 631-642
    • Mitsui, K.1
  • 31
    • 40249093059 scopus 로고    scopus 로고
    • A core Klf circuitry regulates self-renewal of embryonic stem cells
    • Jiang J, et al. (2008) A core Klf circuitry regulates self-renewal of embryonic stem cells. Nat Cell Biol 10(3):353-360.
    • (2008) Nat Cell Biol , vol.10 , Issue.3 , pp. 353-360
    • Jiang, J.1
  • 32
    • 35348982301 scopus 로고    scopus 로고
    • Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
    • Loh YH, Zhang W, Chen X, George J, Ng HH (2007) Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes Dev 21(20): 2545-2557.
    • (2007) Genes Dev , vol.21 , Issue.20 , pp. 2545-2557
    • Loh, Y.H.1    Zhang, W.2    Chen, X.3    George, J.4    Ng, H.H.5
  • 33
    • 56249128625 scopus 로고    scopus 로고
    • Zfp143 regulates Nanog through modulation of Oct4 binding
    • Chen X, Fang F, Liou YC, Ng HH (2008) Zfp143 regulates Nanog through modulation of Oct4 binding. Stem Cells 26(11):2759-2767.
    • (2008) Stem Cells , vol.26 , Issue.11 , pp. 2759-2767
    • Chen, X.1    Fang, F.2    Liou, Y.C.3    Ng, H.H.4
  • 34
    • 33646527782 scopus 로고    scopus 로고
    • Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway
    • Chazaud C, Yamanaka Y, Pawson T, Rossant J (2006) Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev Cell 10(5):615-624.
    • (2006) Dev Cell , vol.10 , Issue.5 , pp. 615-624
    • Chazaud, C.1    Yamanaka, Y.2    Pawson, T.3    Rossant, J.4
  • 35
    • 84865782346 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 homodimerization rapidly reduces transcription of the pluripotency gene Nanog without dissociation of activating transcription factors
    • Santostefano KE, Hamazaki T, Pardo CE, Kladde MP, Terada N (2012) Fibroblast growth factor receptor 2 homodimerization rapidly reduces transcription of the pluripotency gene Nanog without dissociation of activating transcription factors. J Biol Chem 287(36):30507-30517.
    • (2012) J Biol Chem , vol.287 , Issue.36 , pp. 30507-30517
    • Santostefano, K.E.1    Hamazaki, T.2    Pardo, C.E.3    Kladde, M.P.4    Terada, N.5
  • 36
    • 11844278314 scopus 로고    scopus 로고
    • Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay
    • Ogilvie RL, et al. (2005) Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay. J Immunol 174(2):953-961.
    • (2005) J Immunol , vol.174 , Issue.2 , pp. 953-961
    • Ogilvie, R.L.1
  • 37
    • 34548241289 scopus 로고    scopus 로고
    • Tristetraprolin regulates TNF TNF-alpha mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways
    • Deleault KM, Skinner SJ, Brooks SA (2008) Tristetraprolin regulates TNF TNF-alpha mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways. Mol Immunol 45(1):13-24.
    • (2008) Mol Immunol , vol.45 , Issue.1 , pp. 13-24
    • Deleault, K.M.1    Skinner, S.J.2    Brooks, S.A.3
  • 38
    • 0033959125 scopus 로고    scopus 로고
    • HuR regulates p21 mRNA stabilization by UV light
    • Wang W, et al. (2000) HuR regulates p21 mRNA stabilization by UV light. Mol Cell Biol 20(3):760-769.
    • (2000) Mol Cell Biol , vol.20 , Issue.3 , pp. 760-769
    • Wang, W.1
  • 39
    • 20044388720 scopus 로고    scopus 로고
    • Involvement of microRNA in AU-rich element-mediated mRNA instability
    • Jing Q, et al. (2005) Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell 120(5):623-634.
    • (2005) Cell , vol.120 , Issue.5 , pp. 623-634
    • Jing, Q.1
  • 40
    • 83455229884 scopus 로고    scopus 로고
    • Primitive endoderm differentiates via a three-step mechanism involving Nanog and RTK signaling
    • Frankenberg S, et al. (2011) Primitive endoderm differentiates via a three-step mechanism involving Nanog and RTK signaling. Dev Cell 21(6):1005-1013.
    • (2011) Dev Cell , vol.21 , Issue.6 , pp. 1005-1013
    • Frankenberg, S.1
  • 41
    • 84867142057 scopus 로고    scopus 로고
    • Signaling by FGF4 and FGF8 is required for axial elongation of the mouse embryo
    • Boulet AM, Capecchi MR (2012) Signaling by FGF4 and FGF8 is required for axial elongation of the mouse embryo. Dev Biol 371(2):235-245.
    • (2012) Dev Biol , vol.371 , Issue.2 , pp. 235-245
    • Boulet, A.M.1    Capecchi, M.R.2
  • 42
    • 0033565746 scopus 로고    scopus 로고
    • Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo
    • Sun X, Meyers EN, Lewandoski M, Martin GR (1999) Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. Genes Dev 13(14): 1834-1846.
    • (1999) Genes Dev , vol.13 , Issue.14 , pp. 1834-1846
    • Sun, X.1    Meyers, E.N.2    Lewandoski, M.3    Martin, G.R.4
  • 43
    • 0029163946 scopus 로고
    • Mesoderm formation in response to Brachyury requires FGF signalling
    • Schulte-Merker S, Smith JC (1995) Mesoderm formation in response to Brachyury requires FGF signalling. Curr Biol 5(1):62-67.
    • (1995) Curr Biol , vol.5 , Issue.1 , pp. 62-67
    • Schulte-Merker, S.1    Smith, J.C.2
  • 44
    • 0031885801 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction
    • Xu X, et al. (1998) Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. Development 125(4):753-765.
    • (1998) Development , vol.125 , Issue.4 , pp. 753-765
    • Xu, X.1
  • 45
    • 0037313844 scopus 로고    scopus 로고
    • Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
    • Ying QL, Stavridis M, Griffiths D, Li M, Smith A (2003) Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol 21(2):183-186.
    • (2003) Nat Biotechnol , vol.21 , Issue.2 , pp. 183-186
    • Ying, Q.L.1    Stavridis, M.2    Griffiths, D.3    Li, M.4    Smith, A.5
  • 46
    • 84871946825 scopus 로고    scopus 로고
    • Streaming fragment assignment for real-time analysis of sequencing experiments
    • Roberts A, Pachter L (2013) Streaming fragment assignment for real-time analysis of sequencing experiments. Nat Methods 10(1):71-73.
    • (2013) Nat Methods , vol.10 , Issue.1 , pp. 71-73
    • Roberts, A.1    Pachter, L.2
  • 47
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • Trapnell C, et al. (2010) Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 28(5):511-515.
    • (2010) Nat Biotechnol , vol.28 , Issue.5 , pp. 511-515
    • Trapnell, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.