Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory T cells

Journal of Translational Medicine

Volumn 12, Issue 1, 2014, Pages

  Ye, Wei ^a,b   Xing, Yun ^b,c   Paustian, Christopher ^b   van de Ven, Rieneke ^b   Moudgil, Tarsem ^b   Hilton, Traci L ^d   Fox, Bernard A ^b,e   Urba, Walter J ^b   Zhao, Wei ^a   Hu, Hong Ming ^a,b  

^a SOUTHEAST UNIVERSITY   (China)

^b EARLE A CHILES RESEARCH INSTITUTE   (United States)

^c CHINA PHARMACEUTICAL UNIVERSITY   (China)

^d Ubivac   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Autophagosome; Cancer vaccine; Cross presentation; Immunological monitoring; Immunotherapy biomarker; Memory antigen specific T cells; Proteasome; Viral vaccine

Indexed keywords

ALPHA INTERFERON; CYTOMEGALOVIRUS ANTIGEN PP65; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA A2 ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; POLYINOSINIC POLYCYTIDYLIC ACID; TUMOR NECROSIS FACTOR ALPHA; VIRUS ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN;

ADOPTIVE IMMUNOTHERAPY; ANTIGEN SPECIFICITY; ARTICLE; AUTOPHAGOSOME; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ISOLATION; CELL LYSATE; CONTROLLED STUDY; CPG ISLAND; CROSS PRESENTATION; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; DEFECTIVE RIBOSOMAL PRODUCTS IN BLEB; EPSTEIN BARR VIRUS; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; INFLUENZA VIRUS; MEMORY T LYMPHOCYTE; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; STAINING; T LYMPHOCYTE ACTIVATION; CELL LINE; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; T LYMPHOCYTE;

ANTIGENS, CD4; ANTIGENS, CD8; ANTIGENS, VIRAL; CELL LINE; CYTOMEGALOVIRUS; HEK293 CELLS; HUMANS; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; T-LYMPHOCYTES;

EID: 84899651440     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-12-100     Document Type: Article

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