Impact of grafting on the design of new membrane adsorbers for adenovirus purification

Journal of Biotechnology

Volumn 181, Issue , 2014, Pages 1-11

  Nestola, Piergiuseppe ^a,b   Villain, Louis ^c   Peixoto, Cristina ^a   Martins, Duarte L ^a,b   Alves, Paula M ^a,b   Carrondo, Manuel J T ^a,b,d   Mota, José P B ^a,e  

^a INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLÓGICA   (Portugal)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^c SARTORIUS STEDIM BIOTECH GMBH   (Germany)

^d UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^e DEPARTAMENTO DE QUÍMICA   (Portugal)

Author keywords

Adenovirus adsorption; Hydrogel grafting; Ligand density; Membrane chromatography; Virus purification

Indexed keywords

CHROMATOGRAPHY; EXPERIMENTS; GRAFTING (CHEMICAL); HYDROGELS; LIGANDS; MEMBRANES; RECOVERY; VIRUSES;

ADENOVIRUS PURIFICATION; BENCHMARK COMPARISON; DYNAMIC BINDING CAPACITY; HIGH-THROUGHPUT SCREENING; LIGAND DENSITY; MEMBRANE CHROMATOGRAPHY; OPERATING CONDITION; VIRUS PURIFICATION;

PURIFICATION;

AMINE; DNA; LIGAND; ARTIFICIAL MEMBRANE; HYDROGEL;

ARTICLE; CHEMICAL STRUCTURE; CHROMATOGRAPHY; CLEARANCE; CONTROLLED STUDY; DENSITY; HIGH THROUGHPUT SCREENING; HUMAN ADENOVIRUS 5; HYDROGEL; MEMBRANE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN BINDING; VIRUS PURIFICATION; ADENOVIRIDAE; ADSORPTION; ARTIFICIAL MEMBRANE; CHEMISTRY; ION EXCHANGE CHROMATOGRAPHY; ISOLATION AND PURIFICATION;

ADENOVIRIDAE; ADSORPTION; CHROMATOGRAPHY, ION EXCHANGE; HYDROGEL; LIGANDS; MEMBRANES, ARTIFICIAL;

EID: 84899647051     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2014.04.003     Document Type: Article

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