Carbosilane dendrimers as gene delivery agents for the treatment of HIV infection

Journal of Controlled Release

Volumn 184, Issue 1, 2014, Pages 51-57

  Perisé Barrios, Ana Judith ^a,d   Jiménez, José Luis ^b,d   D'Omínguez Soto, Angeles ^e   De La Mata, F Javier ^c,d   Corbí, Angel L ^e   Gomez, Rafael ^c,d   Muñoz Fernandez, María Ángeles ^a,d  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^c UNIVERSITY OF ALCALÁ   (Spain)

^d BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^e CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Carbosilane dendrimers; CD4 lymphocytes and macrophages; Gene therapy; HIV infection; siRNA delivery

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; GENE THERAPY; GENE TRANSFER; MACROPHAGES; T-CELLS;

CARBOSILANE DENDRIMER; CD4 T-LYMPHOCYTES; GENE DELIVERY AGENTS; HIV INFECTION; INFLAMMATORY RESPONSE; MACROPHAGE PHENOTYPES; SECOND GENERATION; SIRNA DELIVERY;

DENDRIMERS;

ANTIGEN P24; CARBOSILANE DENDRIMER; CCL1 CHEMOKINE; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; DENDRIMER; EOTAXIN 2; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; MONOCYTE CHEMOTACTIC PROTEIN 4; NANOCONJUGATE; RANTES; SECONDARY LYMPHOID TISSUE CHEMOKINE; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2G-03NN24; 2G-NN16; CYTOKINE; LIPOPOLYSACCHARIDE; NEF PROTEIN; ORGANOSILICON DERIVATIVE; SILANE DERIVATIVE; SMALL INTERFERING RNA;

ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION ASSAY; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; FLOW CYTOMETRY; GEL ELECTROPHORESIS; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATION; MACROPHAGE; MTT ASSAY; PHAGOCYTOSIS; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SAFETY; SYNTHESIS; VIRUS REPLICATION; CELL CULTURE; CELL SURVIVAL; DRUG EFFECTS; GENE TRANSFER; GENETICS; HIV INFECTIONS; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGY; MONONUCLEAR CELL; PHYSIOLOGY; VIROLOGY;

CD4-POSITIVE T-LYMPHOCYTES; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; DENDRIMERS; GENE PRODUCTS, NEF; GENE TRANSFER TECHNIQUES; HIV INFECTIONS; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MACROPHAGES; ORGANOSILICON COMPOUNDS; PHAGOCYTOSIS; RNA, SMALL INTERFERING; SILANES; VIRUS REPLICATION;

EID: 84899644864     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.03.048     Document Type: Article

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