WT1 and kidney progenitor cells

Organogenesis

Volumn 6, Issue 2, 2010, Pages 61-70

  Kreidberg, Jordan A ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

Chromatin immunoprecipitation; Kidney development; Morpholino oligonucleotide; Progenitor cell; Transcription factor; WT1

Indexed keywords

FIBROBLAST GROWTH FACTOR 8; OSTEOGENIC PROTEIN 1; RNA BINDING PROTEIN; WNT4 PROTEIN; WNT9B PROTEIN; WT1 PROTEIN;

CELL DIFFERENTIATION; CELL GROWTH; GENE EXPRESSION; GENE IDENTIFICATION; KIDNEY; MESENCHYME CELL; REVIEW; RNA BINDING; SIGNAL TRANSDUCTION; STEM CELL;

EID: 77953481111     PISSN: 15476278     EISSN: 15558592     Source Type: Journal    
DOI: 10.4161/org.6.2.11928     Document Type: Review

References (52)

1. Kreidberg JA, Sariola H, Loring JM, Maeda M, Pelletier J, Housman D, et al. WT-1 is required for early kidney development. Cell 1993; 74:679-91.
2. Hartwig S, Ho J, Pandey P, Macisaac K, Taglienti M, Xiang M, et al. Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development. Development 2010; 137:1189-203.
3. Little MH, Brennan J, Georgas K, Davies JA, Davidson DR, Baldock RA, et al. A high-resolution anatomical ontology of the developing murine genitourinary tract. Gene Expr Patterns 2007; 7:680-99. (Pubitemid 46796774)
4. Saxen L. Organogenesis of the Kidney. Cambridge: Cambridge University Press 1987.
5. Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, et al. Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature 2003; 426:247-54.
6. Xu PX, Adams J, Peters H, Brown MC, Heaney S, Maas R. Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nat Genet 1999; 23:113-7.
7. Xu PX, Zheng W, Huang L, Maire P, Laclef C, Silvius D. Six1 is required for the early organogenesis of mammalian kidney. Development 2003; 130:3085-94. (Pubitemid 36926948)
8. Costantini F. Renal branching morphogenesis: concepts, questions and recent advances. Differentiation 2006; 74:402-21. (Pubitemid 44215411)
9. Moore MW, Klein RD, Farinas I, Sauer H, Armani M, Philips H, et al. Renal and neuronal abnormalities in mice lacking GDNF. Nature 1996; 382:76-9. (Pubitemid 26243361)
10. Pichel JG, Shen L, Sheng HZ, Granholm A-C, Drago J, Grinberg A, et al. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 1996; 382:73-6.
11. Sainio K, Suvanto P, Davies J, Wartiovaara J, Wartiovaara K, Saarma M, et al. Glial-cell-linederived neurotrophic factor is required for bud initiation from ureteric epithelium. Development 1997; 124:4077-87.
12. Sanchez MP, Silos SI, Frisen J, He B, Lira SA, Barbacid M. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 1996; 382:70-3.
13. Gao X, Chen X, Taglienti M, Rumballe B, Little MH, Kreidberg JA. Angioblast-mesenchyme induction of early kidney development is mediated by WT1 and Vegfa. Development 2005; 132:5437-49.
14. Bard JBL, McConnell JE, Davies JA. Towards a genetic basis for kidney development. Mechanisms of Development 1994; 48:3-11. (Pubitemid 24294317)
15. Self M, Lagutin OV, Bowling B, Hendrix J, Cai Y, Dressler GR, et al. Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney. EMBO J 2006; 25:5214-28. (Pubitemid 44658538)
16. James RG, Kamei CN, Wang Q, Jiang R, Schultheiss TM. Odd-skipped related 1 is required for development of the metanephric kidney and regulates formation and differentiation of kidney precursor cells. Development 2006; 133:2995-3004. (Pubitemid 44314276)
17. Hartman HA, Lai HL, Patterson LT. Cessation of renal morphogenesis in mice. Dev Biol 2007; 310:379-87.
18. Cebrian C, Borodo K, Charles N, Herzlinger DA. Morphometric index of the developing murine kidney. Dev Dyn 2004; 231:601-8. (Pubitemid 39410894)
19. Boyle S, Misfeldt A, Chandler KJ, Deal KK, Southard-Smith EM, Mortlock DP, et al. Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia. Dev Biol 2008; 313:234-45.
20. Kobayashi A, Valerius MT, Mugford JW, Carroll TJ, Self M, Oliver G, et al. Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell 2008; 3:169-81.
21. Mugford JW, Sipila P, McMahon JA, McMahon AP. Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney. Dev Biol 2008; 324:88-98.
22. Dudley AT, Lyons KM, Robertson EJ. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev 1995; 9:2795-807.
23. Luo G, Hofmann C, Bronckers AL, Sohocki M, Bradley A, Karsenty G. BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes Dev 1995; 9:2808-20.
24. Oxburgh L, Dudley AT, Godin RE, Koonce CH, Islam A, Anderson DC, et al. BMP4 substitutes for loss of BMP7 during kidney development. Dev Biol 2005; 286:637-46. (Pubitemid 41443299)
25. Kazama I, Mahoney Z, Miner JH, Graf D, Economides AN, Kreidberg JA. Podocyte-derived BMP7 is critical for nephron development. J Am Soc Nephrol 2008; 19:2181-91.
26. Perantoni AO, Dove LF, Karavanova I. Basic fibroblast growth factor can mediate the early inductive events in renal development. Proc Natl Acad Sci USA 1995; 92:4696-700.
27. Dudley AT, Godin RE, Robertson EJ. Interaction between FGF and BMP signaling pathways regulates development of metanephric mesenchyme. Genes Dev 1999; 13:1601-13.
28. Poladia DP, Kish K, Kutay B, Hains D, Kegg H, Zhao H, et al. Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme. Dev Biol 2006; 291:325-39.
29. Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR. FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development 2005; 132:3847-57. (Pubitemid 41410250)
30. Perantoni AO, Timofeeva O, Naillat F, Richman C, Pajni-Underwood S, Wilson C, et al. Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development. Development 2005; 132:3859-71. (Pubitemid 41410251)
31. Kispert A, Vainio S, McMahon AP. Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development 1998; 125:4225-34.
32. Stark K, Vainio S, Vassileva G, McMahon AP. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 1994; 372:679-83.
33. Kreidberg JA, Hartwig S. Wilms' tumor-1: a riddle wrapped in a mystery, inside a kidney. Kidney Int 2008; 74:411-2.
34. Hohenstein P, Hastie ND. The many facets of the Wilms' tumour gene, WT1. Hum Mol Genet 2006; 15:196-201.
35. Scharnhorst V, van der Eb AJ, Jochemsen AG. WT1 proteins: functions in growth and differentiation. Gene 2001; 273:141-61. (Pubitemid 32786908)
36. Dressler GR. The cellular basis of kidney development. Annu Rev Cell Dev Biol 2006; 22:509-29.
37. Dressler GR. Advances in early kidney specification, development and patterning. Development 2009; 136:3863-74.
38. Andersson T, Sodersten E, Duckworth JK, Cascante A, Fritz N, Sacchetti P, et al. CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells. J Biol Chem 2009; 284:3672-81.
39. Kim MS, Yoon SK, Bollig F, Kitagaki J, Hur W, Whye NJ, et al. A novel Wilms Tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway. J Biol Chem 2010; In Press.
40. Anjum R, Blenis J. The RSK family of kinases: emerging roles in cellular signalling. Nat Rev Mol Cell Biol 2008; 9:747-58.
41. Nottke A, Colaiacovo MP, Shi Y. Developmental roles of the histone lysine demethylases. Development 2009; 136:879-89.
42. Abrajano JJ, Qureshi IA, Gokhan S, Zheng D, Bergman A, Mehler MF. REST and CoREST modulate neuronal subtype specification, maturation and maintenance. PLoS One 2009; 4:7936.
43. Cai SY, Babbitt RW, Marchesi VT. A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division. Proc Natl Acad Sci USA 1999; 96:2828-33.
44. Miotto B, Struhl K. HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1. Genes Dev 2008; 22:2633-8.
45. Quaggin SE, Kreidberg JA. Development of the renal glomerulus: good neighbors and good fences. Development 2008; 135:609-20.
46. Surendran K, Boyle S, Barak H, Kim M, Stomberski C, McCright B, Kopan R. The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage. Dev Biol 2001; 337:386-95.
47. Rivera MN, Kim WJ, Wells J, Driscoll DR, Brannigan BW, Han M, et al. An X chromosome gene, WTX, is commonly inactivated in Wilms tumor. Science 2007; 315:642-5.
48. Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, et al. Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling. Science 2007; 316:1043-6.
49. Corbin M, de Reynies A, Rickman DS, Berrebi D, Boccon-Gibod L, Cohen-Gogo S, et al. WNT/ beta-catenin pathway activation in Wilms tumors: a unifying mechanism with multiple entries? Genes Chromosomes Cancer 2009; 48:816-27.
50. Dai C, Stolz DB, Kiss LP, Monga SP, Holzman LB, Liu Y. Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria. J Am Soc Nephrol 2009; 20:1997-2008.
51. Heikkila E, Juhila J, Lassila M, Messing M, Perala N, Lehtonen E, et al. {beta}-Catenin mediates adriamycin-induced albuminuria and podocyte injury in the adult mouse kidneys. Nephrol Dial Transplant 2010; (in press).
52. Cook DM, Hinkes MT, Bernfield M, III FJR. Transcriptional activation of the syndecan-1 promoter by the Wilms' tumor protein WT1. Oncogene 1996; 13:1789-99. (Pubitemid 26377512)