-
1
-
-
80052273289
-
Direct ink writing of highly porous and strong glass scaffolds for load-bearing bone defects repair and regeneration
-
Fu Q, Saiz E, Tomsia A P. Direct ink writing of highly porous and strong glass scaffolds for load-bearing bone defects repair and regeneration. Acta Biomaterialia, 2011, 7(10): 3547-3554.
-
(2011)
Acta Biomaterialia
, vol.7
, Issue.10
, pp. 3547-3554
-
-
Fu, Q.1
Saiz, E.2
Tomsia, A.P.3
-
2
-
-
84871050662
-
Comparison of four reconstructive methods for diaphyseal defects of the humerus after tumor resection
-
Sakellariou V I, Mavrogenis A F, Babis G C, et al. Comparison of four reconstructive methods for diaphyseal defects of the humerus after tumor resection. Journal of Applied Biomechanics, 2012, 28(5): 568-578.
-
(2012)
Journal of Applied Biomechanics
, vol.28
, Issue.5
, pp. 568-578
-
-
Sakellariou, V.I.1
Mavrogenis, A.F.2
Babis, G.C.3
-
3
-
-
84884926202
-
Accelerated weightbearing rehabilitation after matrix-induced autologous chondrocyte implantation in the tibiofemoral joint: early clinical and radiological outcomes
-
Edwards P K, Ackland T R, Ebert J R. Accelerated weightbearing rehabilitation after matrix-induced autologous chondrocyte implantation in the tibiofemoral joint: early clinical and radiological outcomes. The American Journal of Sports Medicine, 2013, 41(10): 2314-2324.
-
(2013)
The American Journal of Sports Medicine
, vol.41
, Issue.10
, pp. 2314-2324
-
-
Edwards, P.K.1
Ackland, T.R.2
Ebert, J.R.3
-
4
-
-
67651174468
-
A prospective, randomized, blinded, single-site study to evaluate the clinical and radiographic differences between frozen and freeze-dried allograft when used as part of a circumferential anterior lumbar interbody fusion procedure
-
Thalgott J S, Fogarty M E, Giuffre J M, et al. A prospective, randomized, blinded, single-site study to evaluate the clinical and radiographic differences between frozen and freeze-dried allograft when used as part of a circumferential anterior lumbar interbody fusion procedure. Spine, 2009, 34(12): 1251-1256.
-
(2009)
Spine
, vol.34
, Issue.12
, pp. 1251-1256
-
-
Thalgott, J.S.1
Fogarty, M.E.2
Giuffre, J.M.3
-
5
-
-
84877718635
-
Unique microstructural design of ceramic scaffolds for bone regeneration under load
-
Roohani-Esfahani S I, Dunstan C R, Li J J, et al. Unique microstructural design of ceramic scaffolds for bone regeneration under load. Acta Biomaterialia, 2013, 9(6): 7014-7024.
-
(2013)
Acta Biomaterialia
, vol.9
, Issue.6
, pp. 7014-7024
-
-
Roohani-Esfahani, S.I.1
Dunstan, C.R.2
Li, J.J.3
-
6
-
-
67849124161
-
Biological performance of a polycaprolactone-based scaffold used as fusion cage device in a large animal model of spinal reconstructive surgery
-
Abbah S A, Lam C X, Hutmacher D W, et al. Biological performance of a polycaprolactone-based scaffold used as fusion cage device in a large animal model of spinal reconstructive surgery. Biomaterials, 2009, 30(28): 5086-5093.
-
(2009)
Biomaterials
, vol.30
, Issue.28
, pp. 5086-5093
-
-
Abbah, S.A.1
Lam, C.X.2
Hutmacher, D.W.3
-
7
-
-
84888812718
-
Biomechanical behavior of bone scaffolds made of additive manufactured tricalciumphosphate and titanium alloy under different loading conditions
-
Wieding J, Fritsche A, Heinl P, et al. Biomechanical behavior of bone scaffolds made of additive manufactured tricalciumphosphate and titanium alloy under different loading conditions. Journal of Applied Biomaterials Functional Materials, 2013, 11(3): 159-166.
-
(2013)
Journal of Applied Biomaterials Functional Materials
, vol.11
, Issue.3
, pp. 159-166
-
-
Wieding, J.1
Fritsche, A.2
Heinl, P.3
-
8
-
-
0347298727
-
Comparison of the bone modeling effects caused by curved and straight nickel - titanium intramedullary nails
-
Kujala S, Tuukkanen J, Jämsä T, et al. Comparison of the bone modeling effects caused by curved and straight nickel - titanium intramedullary nails. Journal of Materials Science: Materials in Medicine, 2002, 13(12): 1157-1161.
-
(2002)
Journal of Materials Science: Materials in Medicine
, vol.13
, Issue.12
, pp. 1157-1161
-
-
Kujala, S.1
Tuukkanen, J.2
Jämsä, T.3
-
9
-
-
84890550902
-
Fusion and subsidence rate of stand alone anterior lumbar interbody fusion using PEEK cage with recombinant human bone morphogenetic protein-2
-
Behrbalk E, Uri O, Parks R M, et al. Fusion and subsidence rate of stand alone anterior lumbar interbody fusion using PEEK cage with recombinant human bone morphogenetic protein-2. European Spine Journal, 2013, 22(12): 2869-2875.
-
(2013)
European Spine Journal
, vol.22
, Issue.12
, pp. 2869-2875
-
-
Behrbalk, E.1
Uri, O.2
Parks, R.M.3
-
10
-
-
0032917632
-
Bone tissue response to biodegradable polymers used for intra medullary fracture fixation: a long-term in vivo study in sheep femora
-
van der Elst M, Klein C P, de Blieck-Hogervorst J M, et al. Bone tissue response to biodegradable polymers used for intra medullary fracture fixation: a long-term in vivo study in sheep femora. Biomaterials, 1999, 20(2): 121-128.
-
(1999)
Biomaterials
, vol.20
, Issue.2
, pp. 121-128
-
-
van der Elst, M.1
Klein, C.P.2
de Blieck-Hogervorst, J.M.3
-
11
-
-
23244458807
-
Is autograft the gold standard in achieving radiographic fusion in one-level anterior cervical discectomy and fusion with rigid anterior plate fixation?
-
Samartzis D, Shen F H, Goldberg E J, et al. Is autograft the gold standard in achieving radiographic fusion in one-level anterior cervical discectomy and fusion with rigid anterior plate fixation? Spine, 2005, 30(15): 1756-1761.
-
(2005)
Spine
, vol.30
, Issue.15
, pp. 1756-1761
-
-
Samartzis, D.1
Shen, F.H.2
Goldberg, E.J.3
-
12
-
-
0036668303
-
Allograft versus autograft in instrumented posterolateral lumbar spinal fusion: a randomized control trial
-
Gibson S, McLeod I, Wardlaw D, et al. Allograft versus autograft in instrumented posterolateral lumbar spinal fusion: a randomized control trial. Spine, 2002, 27(15): 1599-1603.
-
(2002)
Spine
, vol.27
, Issue.15
, pp. 1599-1603
-
-
Gibson, S.1
McLeod, I.2
Wardlaw, D.3
-
13
-
-
0032149059
-
The correlation between immune rejection and osteoinduction of allogeneic bone grafting
-
Sun L, Hu Y, Ning Z, et al. The correlation between immune rejection and osteoinduction of allogeneic bone grafting. Chinese Medical Journal, 1998, 111(9): 818-822.
-
(1998)
Chinese Medical Journal
, vol.111
, Issue.9
, pp. 818-822
-
-
Sun, L.1
Hu, Y.2
Ning, Z.3
-
14
-
-
55549093737
-
Evaluation of bone plate with low-stiffness material in terms of stress distribution
-
Benli S, Aksoy S, Havitcioǧlu H, et al. Evaluation of bone plate with low-stiffness material in terms of stress distribution. Journal of Biomechanics, 2008, 41(15): 3229-3235.
-
(2008)
Journal of Biomechanics
, vol.41
, Issue.15
, pp. 3229-3235
-
-
Benli, S.1
Aksoy, S.2
Havitcioǧlu, H.3
-
15
-
-
79953716787
-
Hydrolysis and biomineralization of porous PLA microspheres and their influence on cell growth
-
Shi X, Jiang J, Sun L, et al. Hydrolysis and biomineralization of porous PLA microspheres and their influence on cell growth. Colloids and Surfaces B: Biointerfaces, 2011, 85(1): 73-80.
-
(2011)
Colloids and Surfaces B: Biointerfaces
, vol.85
, Issue.1
, pp. 73-80
-
-
Shi, X.1
Jiang, J.2
Sun, L.3
-
16
-
-
34447265981
-
Self-assembly of mineralized collagen composites
-
Cui F Z, Li Y, Ge J. Self-assembly of mineralized collagen composites. Materials Science and Engineering R: Reports, 2007, 57(1-6): 1-27.
-
(2007)
Materials Science and Engineering R: Reports
, vol.57
, Issue.1-6
, pp. 1-27
-
-
Cui, F.Z.1
Li, Y.2
Ge, J.3
-
17
-
-
0033998972
-
Formation of calcium phosphate/collagen composites through mineralization of collagen matrix
-
Du C, Cui F Z, Zhang W, et al. Formation of calcium phosphate/collagen composites through mineralization of collagen matrix. Journal of Biomedical Materials Research, 2000, 50(4): 518-527.
-
(2000)
Journal of Biomedical Materials Research
, vol.50
, Issue.4
, pp. 518-527
-
-
Du, C.1
Cui, F.Z.2
Zhang, W.3
-
18
-
-
0042025172
-
Hierarchical self-assembly of nano-fibrils in mineralized collagen
-
Zhang W, Liao S S, Cui F Z. Hierarchical self-assembly of nano-fibrils in mineralized collagen. Chemistry of Materials, 2003, 15(16): 3221-3226.
-
(2003)
Chemistry of Materials
, vol.15
, Issue.16
, pp. 3221-3226
-
-
Zhang, W.1
Liao, S.S.2
Cui, F.Z.3
-
19
-
-
2442419695
-
Hierarchically biomimetic bone scaffold materials: nano-HA/collagen/PLA composite
-
Liao S S, Cui F Z, Zhang W, et al. Hierarchically biomimetic bone scaffold materials: nano-HA/collagen/PLA composite. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2004, 69B(2): 158-165.
-
(2004)
Journal of Biomedical Materials Research Part B: Applied Biomaterials
, vol.69 B
, Issue.2
, pp. 158-165
-
-
Liao, S.S.1
Cui, F.Z.2
Zhang, W.3
-
20
-
-
84869137592
-
China's push in tissue engineering
-
Hvistendahl M. China's push in tissue engineering. Science, 2012, 338(6109): 900-902.
-
(2012)
Science
, vol.338
, Issue.6109
, pp. 900-902
-
-
Hvistendahl, M.1
-
21
-
-
84899549939
-
The mineralized collagen for the reconstruction of intra-articular calcaneal fractures with trabecular defects
-
Lian K, Lu H, Guo X, et al. The mineralized collagen for the reconstruction of intra-articular calcaneal fractures with trabecular defects. Biomatter, 2013, 3(4): e27250 (5 pages).
-
(2013)
Biomatter
, vol.3
, Issue.4
-
-
Lian, K.1
Lu, H.2
Guo, X.3
-
22
-
-
84876217103
-
Clinical evaluation of mineralized collagen as a bone graft substitute for anterior cervical intersomatic fusion
-
Yu X, Xu L, Cui F Z, et al. Clinical evaluation of mineralized collagen as a bone graft substitute for anterior cervical intersomatic fusion. Journal of Biomaterials and Tissue Engineering, 2012, 2(2): 170-176.
-
(2012)
Journal of Biomaterials and Tissue Engineering
, vol.2
, Issue.2
, pp. 170-176
-
-
Yu, X.1
Xu, L.2
Cui, F.Z.3
-
23
-
-
52649150222
-
Dynamics of in vitro polymer degradation of polycaprolactone-based scaffolds: accelerated versus simulated physiological conditions
-
Lam C X F, Savalani M M, Teoh S-H, et al. Dynamics of in vitro polymer degradation of polycaprolactone-based scaffolds: accelerated versus simulated physiological conditions. Biomedical Materials, 2008, 3(3): 034108.
-
(2008)
Biomedical Materials
, vol.3
, Issue.3
, pp. 034108
-
-
Lam, C.X.F.1
Savalani, M.M.2
Teoh, S.-H.3
-
24
-
-
84899623389
-
Novel approaches towards primate toxicology
-
G. F. Weinbauer and F. Vogel (Eds.), Münster: Waxmann
-
Willnecker J. Novel approaches towards primate toxicology. In: Weinbauer G F, Vogel F, eds. Novel Approaches towards Primate Toxicology. Münster: Waxmann, 2006, 13-19.
-
(2006)
Novel Approaches Towards Primate Toxicology
, pp. 13-19
-
-
Willnecker, J.1
-
26
-
-
84555170196
-
Biocompatibility of 17-4 PH stainless steel foam for implant applications
-
Mutlu I, Oktay E. Biocompatibility of 17-4 PH stainless steel foam for implant applications. Bio-Medical Materials and Engineering, 2011, 21(4): 223-233.
-
(2011)
Bio-Medical Materials and Engineering
, vol.21
, Issue.4
, pp. 223-233
-
-
Mutlu, I.1
Oktay, E.2
-
27
-
-
33644557706
-
Cancellous bone from porous Ti6Al4V by multiple coating technique
-
Li J P, Li S H, van Blitterswijk C A, et al. Cancellous bone from porous Ti6Al4V by multiple coating technique. Journal of Materials Science: Materials in Medicine, 2006, 17(2): 179-185.
-
(2006)
Journal of Materials Science: Materials in Medicine
, vol.17
, Issue.2
, pp. 179-185
-
-
Li, J.P.1
Li, S.H.2
van Blitterswijk, C.A.3
-
28
-
-
84878985049
-
Tissue properties of the human vertebral body sub-structures evaluated by means of microindentation
-
Dall'Ara E, Karl C, Mazza G, et al. Tissue properties of the human vertebral body sub-structures evaluated by means of microindentation. Journal of the Mechanical Behavior of Biomedical Materials, 2013, 25: 23-32.
-
(2013)
Journal of the Mechanical Behavior of Biomedical Materials
, vol.25
, pp. 23-32
-
-
Dall'Ara, E.1
Karl, C.2
Mazza, G.3
-
29
-
-
34249746868
-
Apparent Young's modulus of human radius using inverse finite-element method
-
Bosisio M R, Talmant M, Skalli W, et al. Apparent Young's modulus of human radius using inverse finite-element method. Journal of Biomechanics, 2007, 40(9): 2022-2028.
-
(2007)
Journal of Biomechanics
, vol.40
, Issue.9
, pp. 2022-2028
-
-
Bosisio, M.R.1
Talmant, M.2
Skalli, W.3
-
30
-
-
84862203871
-
Quantitative proteomic analysis of human osteoblast-like MG-63 cells in response to bioinert implant material titanium and polyetheretherketone
-
Zhao M, An M, Wang Q, et al. Quantitative proteomic analysis of human osteoblast-like MG-63 cells in response to bioinert implant material titanium and polyetheretherketone. Journal of Proteomics, 2012, 75(12): 3560-3573.
-
(2012)
Journal of Proteomics
, vol.75
, Issue.12
, pp. 3560-3573
-
-
Zhao, M.1
An, M.2
Wang, Q.3
-
31
-
-
21444442365
-
Grafting reaction of poly(D,L) lactic acid with maleic anhydride and hexanediamine to introduce more reactive groups in its bulk
-
Pan J, Wang Y, Qin S, et al. Grafting reaction of poly(D, L) lactic acid with maleic anhydride and hexanediamine to introduce more reactive groups in its bulk. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2005, 74B(1): 476-480.
-
(2005)
Journal of Biomedical Materials Research Part B: Applied Biomaterials
, vol.74 B
, Issue.1
, pp. 476-480
-
-
Pan, J.1
Wang, Y.2
Qin, S.3
-
32
-
-
55249118801
-
The development of peptidebased interfacial biomaterials for generating biological functionality on the surface of bioinert materials
-
Meyers S R, Khoo X, Huang X, et al. The development of peptidebased interfacial biomaterials for generating biological functionality on the surface of bioinert materials. Biomaterials, 2009, 30(3): 277-286.
-
(2009)
Biomaterials
, vol.30
, Issue.3
, pp. 277-286
-
-
Meyers, S.R.1
Khoo, X.2
Huang, X.3
-
33
-
-
84891412153
-
Co-blasting of titanium surfaces with an abrasive and hydroxyapatite to produce bioactive coatings: substrate and coating characterisation
-
Dunne C F, Twomey B, O'Neill L, et al. Co-blasting of titanium surfaces with an abrasive and hydroxyapatite to produce bioactive coatings: substrate and coating characterisation. Journal of Biomaterials Applications, 2014, 28(5): 767-778.
-
(2014)
Journal of Biomaterials Applications
, vol.28
, Issue.5
, pp. 767-778
-
-
Dunne, C.F.1
Twomey, B.2
O'Neill, L.3
-
34
-
-
84876411058
-
Bone morphogenic protein-2 (BMP-2) loaded hybrid coating on porous hydroxyapatite scaffolds for bone tissue engineering
-
Jun S H, Lee E J, Jang T S, et al. Bone morphogenic protein-2 (BMP-2) loaded hybrid coating on porous hydroxyapatite scaffolds for bone tissue engineering. Journal of Materials Science: Materials in Medicine, 2013, 24(3): 773-782.
-
(2013)
Journal of Materials Science: Materials in Medicine
, vol.24
, Issue.3
, pp. 773-782
-
-
Jun, S.H.1
Lee, E.J.2
Jang, T.S.3
-
35
-
-
84894157656
-
Fast preparation of free-standing nanohydroxyapatite-vertically aligned carbon nanotube scaffolds
-
Grinet M A V M, Zanin H, Campos Granato A E, et al. Fast preparation of free-standing nanohydroxyapatite-vertically aligned carbon nanotube scaffolds. Journal of Materials Chemistry B, 2014, 2(9): 1196-1204.
-
(2014)
Journal of Materials Chemistry B
, vol.2
, Issue.9
, pp. 1196-1204
-
-
Grinet, M.A.V.M.1
Zanin, H.2
Campos Granato, A.E.3
-
36
-
-
84873255574
-
Cleavage of hyaluronan is impaired in aged dermal wounds
-
Reed M J, Damodarasamy M, Chan C K, et al. Cleavage of hyaluronan is impaired in aged dermal wounds. Matrix Biology, 2013, 32(1): 45-51.
-
(2013)
Matrix Biology
, vol.32
, Issue.1
, pp. 45-51
-
-
Reed, M.J.1
Damodarasamy, M.2
Chan, C.K.3
-
37
-
-
84881597799
-
Achilles tendon: functional anatomy and novel emerging models of imaging classification
-
Del Buono A, Chan O, Maffulli N. Achilles tendon: functional anatomy and novel emerging models of imaging classification. International Orthopaedics, 2013, 37(4): 715-721.
-
(2013)
International Orthopaedics
, vol.37
, Issue.4
, pp. 715-721
-
-
Del Buono, A.1
Chan, O.2
Maffulli, N.3
-
38
-
-
33646553866
-
In vitro ossification and remodeling of mineralized collagen I scaffolds
-
Domaschke H, Gelinsky M, Burmeister B, et al. In vitro ossification and remodeling of mineralized collagen I scaffolds. Tissue Engineering, 2006, 12(4): 949-958.
-
(2006)
Tissue Engineering
, vol.12
, Issue.4
, pp. 949-958
-
-
Domaschke, H.1
Gelinsky, M.2
Burmeister, B.3
-
39
-
-
45749153715
-
Bone regeneration by using scaffold based on mineralized recombinant collagen
-
Wang Y, Cui F Z, Hu K, et al. Bone regeneration by using scaffold based on mineralized recombinant collagen. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2008, 86B(1): 29-35.
-
(2008)
Journal of Biomedical Materials Research Part B: Applied Biomaterials
, vol.86 B
, Issue.1
, pp. 29-35
-
-
Wang, Y.1
Cui, F.Z.2
Hu, K.3
-
40
-
-
1042266511
-
In vitro and in vivo degradation of mineralized collagen-based composite scaffold: nanohydroxyapatite/collagen/poly(L-lactide)
-
Liao S S, Cui F Z. In vitro and in vivo degradation of mineralized collagen-based composite scaffold: nanohydroxyapatite/collagen/poly(L-lactide). Tissue Engineering, 2004, 10(1-2): 73-80.
-
(2004)
Tissue Engineering
, vol.10
, Issue.1-2
, pp. 73-80
-
-
Liao, S.S.1
Cui, F.Z.2
-
41
-
-
84957845379
-
In vitro and in vivo enhancement of osteogenic capacity in a synthetic BMP-2 derived peptidecoated mineralized collagen composite
-
Zhang X, Guo WG, Cui H, et al. In vitro and in vivo enhancement of osteogenic capacity in a synthetic BMP-2 derived peptidecoated mineralized collagen composite. Journal of Tissue Engineering and Regenerative Medicine, 2014, doi: 10. 1002/term. 1705.
-
(2014)
Journal of Tissue Engineering and Regenerative Medicine
-
-
Zhang, X.1
Guo, W.G.2
Cui, H.3
-
42
-
-
61849120845
-
Collagen solubility testing, a quality assurance step for reproducible electro-spun nano-fibre fabrication. A technical note
-
Zeugolis D I, Li B, Lareu R R, et al. Collagen solubility testing, a quality assurance step for reproducible electro-spun nano-fibre fabrication. A technical note. Journal of Biomaterials Science: Polymer Edition, 2008, 19(10): 1307-1317.
-
(2008)
Journal of Biomaterials Science: Polymer Edition
, vol.19
, Issue.10
, pp. 1307-1317
-
-
Zeugolis, D.I.1
Li, B.2
Lareu, R.R.3
-
43
-
-
0017290857
-
Balance between swelling pressure and collagen tension in normal and degenerate cartilage
-
Maroudas A I. Balance between swelling pressure and collagen tension in normal and degenerate cartilage. Nature, 1976, 260(5554): 808-809.
-
(1976)
Nature
, vol.260
, Issue.5554
, pp. 808-809
-
-
Maroudas, A.I.1
-
44
-
-
37049248625
-
Rate of swelling of collagen
-
Elden H R. Rate of swelling of collagen. Science, 1958, 128(3339): 1624-1625.
-
(1958)
Science
, vol.128
, Issue.3339
, pp. 1624-1625
-
-
Elden, H.R.1
-
45
-
-
84877587445
-
Compression molded ultra high molecular weight polyethylene-hydroxyapatite-aluminum oxide-carbon nanotube hybrid composites for hard tissue replacement
-
Gupta A, Tripathi G, Lahiri D, et al. Compression molded ultra high molecular weight polyethylene-hydroxyapatite-aluminum oxide-carbon nanotube hybrid composites for hard tissue replacement. Journal of Materials Science and Technology, 2013, 29(6): 514-522.
-
(2013)
Journal of Materials Science and Technology
, vol.29
, Issue.6
, pp. 514-522
-
-
Gupta, A.1
Tripathi, G.2
Lahiri, D.3
-
46
-
-
33644597445
-
Physicochemical properties of collagen, gelatin and collagen hydrolysate derived from bovine limed split wastes
-
Zhang Z, Li G, Shi B. Physicochemical properties of collagen, gelatin and collagen hydrolysate derived from bovine limed split wastes. Journal of the Society of Leather Technologists and Chemists, 2006, 90(1): 23-28.
-
(2006)
Journal of the Society of Leather Technologists and Chemists
, vol.90
, Issue.1
, pp. 23-28
-
-
Zhang, Z.1
Li, G.2
Shi, B.3
-
47
-
-
40649102606
-
Comparison of dynamic denaturation temperature of collagen with its static denaturation temperature and the configuration characteristics in collagen denaturation processes
-
Li Y, Li Y, Du Z, et al. Comparison of dynamic denaturation temperature of collagen with its static denaturation temperature and the configuration characteristics in collagen denaturation processes. Thermochimica Acta, 2008, 469(1-2): 71-76.
-
(2008)
Thermochimica Acta
, vol.469
, Issue.1-2
, pp. 71-76
-
-
Li, Y.1
Li, Y.2
Du, Z.3
-
48
-
-
49949095955
-
Biomaterials in orthopaedics
-
Navarro M, Michiardi A, Castaño O, et al. Biomaterials in orthopaedics. Journal of the Royal Society: Interface, 2008, 5(27): 1137-1158.
-
(2008)
Journal of the Royal Society: Interface
, vol.5
, Issue.27
, pp. 1137-1158
-
-
Navarro, M.1
Michiardi, A.2
Castaño, O.3
|