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Volumn 32, Issue 1, 2013, Pages 45-51

Cleavage of hyaluronan is impaired in aged dermal wounds

Author keywords

Age; Dermis; Hyaluronan; Hyaluronan synthase; Hyaluronidase; Mice; Wound healing

Indexed keywords

GLUCOSAMINE; HYALURONAN SYNTHASE 2; HYALURONAN SYNTHASE 3; HYALURONIC ACID; HYALURONIDASE 1-3; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 84873255574     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2012.09.004     Document Type: Article
Times cited : (18)

References (58)
  • 1
    • 0028233173 scopus 로고
    • Cells, matrix, growth factors, and the surgeon. The biology of scarless fetal wound repair
    • Adzick N.S., Lorenz H.P. Cells, matrix, growth factors, and the surgeon. The biology of scarless fetal wound repair. Ann. Surg. 1994, 220:10-18.
    • (1994) Ann. Surg. , vol.220 , pp. 10-18
    • Adzick, N.S.1    Lorenz, H.P.2
  • 3
    • 0030789796 scopus 로고    scopus 로고
    • Developmentally programmed expression of hyaluronan in human skin and its appendages
    • Agren U.M., Tammi M., Ryynänen M., Tammi R. Developmentally programmed expression of hyaluronan in human skin and its appendages. J. Invest. Dermatol. 1997, 109:219-224.
    • (1997) J. Invest. Dermatol. , vol.109 , pp. 219-224
    • Agren, U.M.1    Tammi, M.2    Ryynänen, M.3    Tammi, R.4
  • 5
    • 0034910003 scopus 로고    scopus 로고
    • Delayed wound healing in aged rats is associated with increased collagen gel remodeling and contraction by skin fibroblasts, not with differences in apoptotic or myofibroblast cell populations
    • Ballas C.B., Davidson J.M. Delayed wound healing in aged rats is associated with increased collagen gel remodeling and contraction by skin fibroblasts, not with differences in apoptotic or myofibroblast cell populations. Wound Repair Regen. 2001, 9:223-237.
    • (2001) Wound Repair Regen. , vol.9 , pp. 223-237
    • Ballas, C.B.1    Davidson, J.M.2
  • 6
    • 34547103781 scopus 로고    scopus 로고
    • Inducible hyaluronan production reveals differential effects on prostate tumor cell growth and tumor angiogenesis
    • Bharadwaj A.G., Rector K., Simpson M.A. Inducible hyaluronan production reveals differential effects on prostate tumor cell growth and tumor angiogenesis. J. Biol. Chem. 2007, 282:20561-20572.
    • (2007) J. Biol. Chem. , vol.282 , pp. 20561-20572
    • Bharadwaj, A.G.1    Rector, K.2    Simpson, M.A.3
  • 7
    • 84873258877 scopus 로고    scopus 로고
    • Age-related dysregulation of inflammation and innate immunity: lessons learned from rodent models
    • Brubaker A.L., Palmer J.L., Kovacs E.J. Age-related dysregulation of inflammation and innate immunity: lessons learned from rodent models. Aging Dis. 2011, 2:346-360.
    • (2011) Aging Dis. , vol.2 , pp. 346-360
    • Brubaker, A.L.1    Palmer, J.L.2    Kovacs, E.J.3
  • 8
    • 0024388421 scopus 로고
    • Differences between adult and fetal fibroblasts in the regulation of hyaluronate synthesis: correlation with migratory activity
    • Chen W.Y., Grant M.E., Schor A.M., Schor S.L. Differences between adult and fetal fibroblasts in the regulation of hyaluronate synthesis: correlation with migratory activity. J. Cell Sci. 1989, 94:577-584.
    • (1989) J. Cell Sci. , vol.94 , pp. 577-584
    • Chen, W.Y.1    Grant, M.E.2    Schor, A.M.3    Schor, S.L.4
  • 11
    • 67049114124 scopus 로고    scopus 로고
    • Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines
    • de la Motte C., Nigro J., Vasanji A., Rho H., Kessler S., Bandyopadhyay S., Danese S., Fiocchi C., Stern R. Platelet-derived hyaluronidase 2 cleaves hyaluronan into fragments that trigger monocyte-mediated production of proinflammatory cytokines. Am. J. Pathol. 2009, 174:2254-2264.
    • (2009) Am. J. Pathol. , vol.174 , pp. 2254-2264
    • de la Motte, C.1    Nigro, J.2    Vasanji, A.3    Rho, H.4    Kessler, S.5    Bandyopadhyay, S.6    Danese, S.7    Fiocchi, C.8    Stern, R.9
  • 12
    • 0030953252 scopus 로고    scopus 로고
    • Early-response gene signalling is induced by angiogenic oligosaccharides of hyaluronan in endothelial cells. Inhibition by non-angiogenic, high-molecular-weight hyaluronan
    • Deed R., Rooney P., Kumar P., Norton J.D., Smith J., Freemont A.J., Kumar S. Early-response gene signalling is induced by angiogenic oligosaccharides of hyaluronan in endothelial cells. Inhibition by non-angiogenic, high-molecular-weight hyaluronan. Int. J. Cancer 1997, 71:251-256.
    • (1997) Int. J. Cancer , vol.71 , pp. 251-256
    • Deed, R.1    Rooney, P.2    Kumar, P.3    Norton, J.D.4    Smith, J.5    Freemont, A.J.6    Kumar, S.7
  • 13
    • 0037022210 scopus 로고    scopus 로고
    • Platelet-derived growth factor-AB limits the extent of myocardial infarction in a rat model: feasibility of restoring impaired angiogenic capacity in the aging heart
    • Edelberg J.M., Lee S.H., Kaur M., Tang L., Feirt N.M., McCabe S., Bramwell O., Wong S.C., Hong M.K. Platelet-derived growth factor-AB limits the extent of myocardial infarction in a rat model: feasibility of restoring impaired angiogenic capacity in the aging heart. Circulation 2002, 105:608-613.
    • (2002) Circulation , vol.105 , pp. 608-613
    • Edelberg, J.M.1    Lee, S.H.2    Kaur, M.3    Tang, L.4    Feirt, N.M.5    McCabe, S.6    Bramwell, O.7    Wong, S.C.8    Hong, M.K.9
  • 15
    • 70449725213 scopus 로고    scopus 로고
    • Organization of hyaluronan and versican in the extracellular matrix of human fibroblasts treated with the viral mimetic poly I:C
    • Evanko S.P., Potter-Perigo S., Johnson P.Y., Wight T.N. Organization of hyaluronan and versican in the extracellular matrix of human fibroblasts treated with the viral mimetic poly I:C. J. Histochem. Cytochem. 2009, 57:1041-1060.
    • (2009) J. Histochem. Cytochem. , vol.57 , pp. 1041-1060
    • Evanko, S.P.1    Potter-Perigo, S.2    Johnson, P.Y.3    Wight, T.N.4
  • 16
    • 0031554878 scopus 로고    scopus 로고
    • A microtiter-based assay for hyaluronidase activity not requiring specialized reagents
    • Frost G.I., Stern R. A microtiter-based assay for hyaluronidase activity not requiring specialized reagents. Anal. Biochem. 1997, 251:263-269.
    • (1997) Anal. Biochem. , vol.251 , pp. 263-269
    • Frost, G.I.1    Stern, R.2
  • 17
    • 48649091494 scopus 로고    scopus 로고
    • Hyaluronan oligosaccharides are potential stimulators to angiogenesis via RHAMM mediated signal pathway in wound healing
    • Gao F., Yang C.X., Mo W., Liu Y.W., He Y.Q. Hyaluronan oligosaccharides are potential stimulators to angiogenesis via RHAMM mediated signal pathway in wound healing. Clin. Invest. Med. 2008, 31:E106-E116.
    • (2008) Clin. Invest. Med. , vol.31
    • Gao, F.1    Yang, C.X.2    Mo, W.3    Liu, Y.W.4    He, Y.Q.5
  • 20
  • 22
    • 34247154435 scopus 로고    scopus 로고
    • CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2
    • Harada H., Takahashi M. CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2. J. Biol. Chem. 2007, 282:5597-5607.
    • (2007) J. Biol. Chem. , vol.282 , pp. 5597-5607
    • Harada, H.1    Takahashi, M.2
  • 23
    • 0037114938 scopus 로고    scopus 로고
    • Microanalysis of hyaluronan oligosaccharides by polyacrylamide gel electrophoresis and its application to assay of hyaluronidase activity
    • Ikegami-Kawai M., Takahashi T. Microanalysis of hyaluronan oligosaccharides by polyacrylamide gel electrophoresis and its application to assay of hyaluronidase activity. Anal. Biochem. 2002, 311:157-165.
    • (2002) Anal. Biochem. , vol.311 , pp. 157-165
    • Ikegami-Kawai, M.1    Takahashi, T.2
  • 24
    • 0032153358 scopus 로고    scopus 로고
    • Repeated additions of hyaluronan alters granulation tissue deposition in sponge implants in mice
    • Iocono J.A., Krummel T.M., Keefer K.A., Allison G.M., Paul H. Repeated additions of hyaluronan alters granulation tissue deposition in sponge implants in mice. Wound Repair Regen. 1998, 6:442-448.
    • (1998) Wound Repair Regen. , vol.6 , pp. 442-448
    • Iocono, J.A.1    Krummel, T.M.2    Keefer, K.A.3    Allison, G.M.4    Paul, H.5
  • 25
    • 84857029700 scopus 로고    scopus 로고
    • A comprehensive model of hyaluronan turnover in the mouse
    • Jadin L., Bookbinder L.H., Frost G.I. A comprehensive model of hyaluronan turnover in the mouse. Matrix Biol. 2012, 31:81-89.
    • (2012) Matrix Biol. , vol.31 , pp. 81-89
    • Jadin, L.1    Bookbinder, L.H.2    Frost, G.I.3
  • 27
    • 2542435875 scopus 로고    scopus 로고
    • PH and cation-induced thermodynamic stability of human hyaluronan binding protein 1 regulates its hyaluronan affinity
    • Jha B.K., Mitra N., Rana R., Surolia A., Salunke D.M., Datta K. pH and cation-induced thermodynamic stability of human hyaluronan binding protein 1 regulates its hyaluronan affinity. J. Biol. Chem. 2004, 279:23061-23072.
    • (2004) J. Biol. Chem. , vol.279 , pp. 23061-23072
    • Jha, B.K.1    Mitra, N.2    Rana, R.3    Surolia, A.4    Salunke, D.M.5    Datta, K.6
  • 28
    • 78751670809 scopus 로고    scopus 로고
    • Hyaluronan as an immune regulator in human diseases
    • Jiang D., Liang J., Noble P.W. Hyaluronan as an immune regulator in human diseases. Physiol. Rev. 2011, 1:221-264.
    • (2011) Physiol. Rev. , vol.1 , pp. 221-264
    • Jiang, D.1    Liang, J.2    Noble, P.W.3
  • 30
    • 0025911814 scopus 로고
    • Studies in fetal wound healing. V. A prolonged presence of hyaluronic acid characterizes fetal wound fluid
    • Longaker M.T., Chiu E.S., Adzick N.S., Stern M., Harrison M.R., Stern R. Studies in fetal wound healing. V. A prolonged presence of hyaluronic acid characterizes fetal wound fluid. Ann. Surg. 1991, 213:292-296.
    • (1991) Ann. Surg. , vol.213 , pp. 292-296
    • Longaker, M.T.1    Chiu, E.S.2    Adzick, N.S.3    Stern, M.4    Harrison, M.R.5    Stern, R.6
  • 31
    • 0029785697 scopus 로고    scopus 로고
    • Hyaluronic acid and skin: wound healing and aging
    • Manuskiatti W., Maibach H.I. Hyaluronic acid and skin: wound healing and aging. Int. J. Dermatol. 1996, 35:539-544.
    • (1996) Int. J. Dermatol. , vol.35 , pp. 539-544
    • Manuskiatti, W.1    Maibach, H.I.2
  • 32
    • 0026540637 scopus 로고
    • In vivo degradation of fetal wound hyaluronic acid results in increased fibroplasia, collagen deposition, and neovascularization
    • Mast B.A., Haynes J.H., Krummel T.M., Diegelmann R.F., Cohen I.K. In vivo degradation of fetal wound hyaluronic acid results in increased fibroplasia, collagen deposition, and neovascularization. Plast. Reconstr. Surg. 1992, 89:503-509.
    • (1992) Plast. Reconstr. Surg. , vol.89 , pp. 503-509
    • Mast, B.A.1    Haynes, J.H.2    Krummel, T.M.3    Diegelmann, R.F.4    Cohen, I.K.5
  • 33
    • 0028268441 scopus 로고
    • Age-dependent changes of hyaluronan in human skin
    • Meyer L.J., Stern R. Age-dependent changes of hyaluronan in human skin. J. Invest. Dermatol. 1994, 102:385-389.
    • (1994) J. Invest. Dermatol. , vol.102 , pp. 385-389
    • Meyer, L.J.1    Stern, R.2
  • 34
    • 0021509239 scopus 로고
    • Age-related changes in the molecular weight of hyaluronic acid from rat skin
    • Miyamoto I., Nagase S. Age-related changes in the molecular weight of hyaluronic acid from rat skin. Jikken Dobutsu 1984, 33:481-485.
    • (1984) Jikken Dobutsu , vol.33 , pp. 481-485
    • Miyamoto, I.1    Nagase, S.2
  • 35
    • 0029767043 scopus 로고    scopus 로고
    • Synergistic effect of hyaluronan oligosaccharides and vascular endothelial growth factor on angiogenesis in vitro
    • Montesano R., Kumar S., Orci L., Pepper M.S. Synergistic effect of hyaluronan oligosaccharides and vascular endothelial growth factor on angiogenesis in vitro. Lab. Invest. 1996, 75:249-262.
    • (1996) Lab. Invest. , vol.75 , pp. 249-262
    • Montesano, R.1    Kumar, S.2    Orci, L.3    Pepper, M.S.4
  • 36
    • 0032584193 scopus 로고    scopus 로고
    • Changes in the expression of c-myc, RB and tyrosine-phosphorylated proteins during proliferation of NIH 3T3 cells induced by hyaluronic acid
    • Moon S.O., Lee J.H., Kim T.J. Changes in the expression of c-myc, RB and tyrosine-phosphorylated proteins during proliferation of NIH 3T3 cells induced by hyaluronic acid. Exp. Mol. Med. 1998, 30:29-33.
    • (1998) Exp. Mol. Med. , vol.30 , pp. 29-33
    • Moon, S.O.1    Lee, J.H.2    Kim, T.J.3
  • 37
    • 79954752206 scopus 로고    scopus 로고
    • Changes in glycosaminoglycans and related proteoglycans in intrinsically aged human skin in vivo
    • Oh J.H., Kim Y.K., Jung J.Y., Shin J.E., Chung J.H. Changes in glycosaminoglycans and related proteoglycans in intrinsically aged human skin in vivo. Exp. Dermatol. 2011, 20:454-456.
    • (2011) Exp. Dermatol. , vol.20 , pp. 454-456
    • Oh, J.H.1    Kim, Y.K.2    Jung, J.Y.3    Shin, J.E.4    Chung, J.H.5
  • 39
    • 33846033175 scopus 로고    scopus 로고
    • Age-related differences in repair of dermal wounds and myocardial infarcts attenuate during the later stages of healing
    • Reed M.J., Karres N., Eyman D., Vernon R.B., Edelberg J.M. Age-related differences in repair of dermal wounds and myocardial infarcts attenuate during the later stages of healing. In Vivo 2006, 20:801-806.
    • (2006) In Vivo , vol.20 , pp. 801-806
    • Reed, M.J.1    Karres, N.2    Eyman, D.3    Vernon, R.B.4    Edelberg, J.M.5
  • 41
    • 72049133263 scopus 로고    scopus 로고
    • Biological effects of hyaluronan in connective tissues, eye, skin, venous wall. Role in aging
    • Robert L., Robert A.M., Renard G. Biological effects of hyaluronan in connective tissues, eye, skin, venous wall. Role in aging. Pathol. Biol. (Paris) 2010, 58:187-198.
    • (2010) Pathol. Biol. (Paris) , vol.58 , pp. 187-198
    • Robert, L.1    Robert, A.M.2    Renard, G.3
  • 42
    • 79959926935 scopus 로고    scopus 로고
    • The role of hyaluronan produced by Has2 gene expression in development of the spine
    • (Phila Pa 1976)
    • Roughley P.J., Lamplugh L., Lee E.R., Matsumoto K., Yamaguchi Y. The role of hyaluronan produced by Has2 gene expression in development of the spine. Spine 2011, 36:E914-E920. (Phila Pa 1976).
    • (2011) Spine , vol.36
    • Roughley, P.J.1    Lamplugh, L.2    Lee, E.R.3    Matsumoto, K.4    Yamaguchi, Y.5
  • 43
    • 0042320670 scopus 로고    scopus 로고
    • Impaired angiogenesis in aging is associated with alterations in vessel density, matrix composition, inflammatory response, and growth factor expression
    • Sadoun E., Reed M.J. Impaired angiogenesis in aging is associated with alterations in vessel density, matrix composition, inflammatory response, and growth factor expression. J. Histochem. Cytochem. 2003, 51:1119-1130.
    • (2003) J. Histochem. Cytochem. , vol.51 , pp. 1119-1130
    • Sadoun, E.1    Reed, M.J.2
  • 44
    • 61349083680 scopus 로고    scopus 로고
    • Hyaluronan accumulation is elevated in cultures of low density lipoprotein receptor-deficient cells and is altered by manipulation of cell cholesterol content
    • Sakr S.W., Potter-Perigo S., Kinsella M.G., Johnson P.Y., Braun K.R., Goueffic Y., Rosenfeld M.E., Wight T.N. Hyaluronan accumulation is elevated in cultures of low density lipoprotein receptor-deficient cells and is altered by manipulation of cell cholesterol content. J. Biol. Chem. 2008, 283:36195-36204.
    • (2008) J. Biol. Chem. , vol.283 , pp. 36195-36204
    • Sakr, S.W.1    Potter-Perigo, S.2    Kinsella, M.G.3    Johnson, P.Y.4    Braun, K.R.5    Goueffic, Y.6    Rosenfeld, M.E.7    Wight, T.N.8
  • 45
    • 0028034363 scopus 로고
    • Application of angiogenic oligosaccharides of hyaluronan increases blood vessel numbers in rat skin
    • Sattar A., Rooney P., Kumar S., Pye D., West D.C., Scott I., Ledger P. Application of angiogenic oligosaccharides of hyaluronan increases blood vessel numbers in rat skin. J. Invest. Dermatol. 1994, 103:576-579.
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 576-579
    • Sattar, A.1    Rooney, P.2    Kumar, S.3    Pye, D.4    West, D.C.5    Scott, I.6    Ledger, P.7
  • 46
    • 73649131572 scopus 로고    scopus 로고
    • Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation
    • Simpson R.M., Meran S., Thomas D., Stephens P., Bowen T., Steadman R., Phillips A. Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation. Am. J. Pathol. 2009, 175:915-928.
    • (2009) Am. J. Pathol. , vol.175 , pp. 915-928
    • Simpson, R.M.1    Meran, S.2    Thomas, D.3    Stephens, P.4    Bowen, T.5    Steadman, R.6    Phillips, A.7
  • 47
    • 0037174957 scopus 로고    scopus 로고
    • Angiogenic oligosaccharides of hyaluronan induce multiple signaling pathways affecting vascular endothelial cell mitogenic and wound healing responses
    • Slevin M., Kumar S., Gaffney J. Angiogenic oligosaccharides of hyaluronan induce multiple signaling pathways affecting vascular endothelial cell mitogenic and wound healing responses. J. Biol. Chem. 2002, 277:41046-41059.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41046-41059
    • Slevin, M.1    Kumar, S.2    Gaffney, J.3
  • 48
    • 23444445895 scopus 로고    scopus 로고
    • Hyaluronan metabolism: a major paradox in cancer biology
    • Stern R. Hyaluronan metabolism: a major paradox in cancer biology. Pathol. Biol. 2005, 53:372-382.
    • (2005) Pathol. Biol. , vol.53 , pp. 372-382
    • Stern, R.1
  • 49
    • 42949088455 scopus 로고    scopus 로고
    • Hyaluronan in skin: aspects of aging and its pharmacologic modulation
    • Stern R., Maibach H.I. Hyaluronan in skin: aspects of aging and its pharmacologic modulation. Clin. Dermatol. 2008, 26:106-122.
    • (2008) Clin. Dermatol. , vol.26 , pp. 106-122
    • Stern, R.1    Maibach, H.I.2
  • 50
    • 0033398390 scopus 로고    scopus 로고
    • Impaired wound repair and delayed angiogenesis in aged mice
    • Swift M.E., Kleinman H.K., DiPietro L.A. Impaired wound repair and delayed angiogenesis in aged mice. Lab. Invest. 1999, 79:1479-1487.
    • (1999) Lab. Invest. , vol.79 , pp. 1479-1487
    • Swift, M.E.1    Kleinman, H.K.2    DiPietro, L.A.3
  • 51
    • 0035725929 scopus 로고    scopus 로고
    • Age-related alterations in the inflammatory response to dermal injury
    • Swift M.E., Burns A.L., Gray K.L., DiPietro L.A. Age-related alterations in the inflammatory response to dermal injury. J. Invest. Dermatol. 2001, 117:1027-1035.
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 1027-1035
    • Swift, M.E.1    Burns, A.L.2    Gray, K.L.3    DiPietro, L.A.4
  • 52
    • 3042697038 scopus 로고    scopus 로고
    • Hyaluronan: from extracellular glue to pericellular cue
    • Toole B.P. Hyaluronan: from extracellular glue to pericellular cue. Nat. Rev. Cancer 2004, 4:528-539.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 528-539
    • Toole, B.P.1
  • 53
    • 53249117480 scopus 로고    scopus 로고
    • Hyaluronan oligosaccharides as a potential anticancer therapeutic
    • Toole B.P., Ghatak S., Misra S. Hyaluronan oligosaccharides as a potential anticancer therapeutic. Curr. Pharm. Biotechnol. 2008, 9:249-252.
    • (2008) Curr. Pharm. Biotechnol. , vol.9 , pp. 249-252
    • Toole, B.P.1    Ghatak, S.2    Misra, S.3
  • 54
    • 0027410121 scopus 로고
    • CD44 positive macrophages take up hyaluronan during lung development
    • Underhill C.B., Nguyen H.A., Shizari M., Culty M. CD44 positive macrophages take up hyaluronan during lung development. Dev. Biol. 1993, 155:324-336.
    • (1993) Dev. Biol. , vol.155 , pp. 324-336
    • Underhill, C.B.1    Nguyen, H.A.2    Shizari, M.3    Culty, M.4
  • 55
    • 0022572291 scopus 로고
    • A model for the role of hyaluronic acid and fibrin in the early events during the inflammatory response and wound healing
    • Weigel P.H., Fuller G.M., LeBoeuf R.D. A model for the role of hyaluronic acid and fibrin in the early events during the inflammatory response and wound healing. J. Theor. Biol. 1986, 119:219-234.
    • (1986) J. Theor. Biol. , vol.119 , pp. 219-234
    • Weigel, P.H.1    Fuller, G.M.2    LeBoeuf, R.D.3
  • 56
    • 0021834944 scopus 로고
    • Angiogenesis induced by degradation products of hyaluronic acid
    • West D.C., Hampson I.N., Arnold F., Kumar S. Angiogenesis induced by degradation products of hyaluronic acid. Science 1985, 228:1324-1326.
    • (1985) Science , vol.228 , pp. 1324-1326
    • West, D.C.1    Hampson, I.N.2    Arnold, F.3    Kumar, S.4
  • 57
    • 0031024038 scopus 로고    scopus 로고
    • Fibrotic healing of adult and late gestation fetal wounds correlates with increased hyaluronidase activity and removal of hyaluronan
    • West D.C., Shaw D.M., Lorenz P., Adzick N.S., Longaker M.T. Fibrotic healing of adult and late gestation fetal wounds correlates with increased hyaluronidase activity and removal of hyaluronan. Int. J. Biochem. Cell Biol. 1997, 29:201-210.
    • (1997) Int. J. Biochem. Cell Biol. , vol.29 , pp. 201-210
    • West, D.C.1    Shaw, D.M.2    Lorenz, P.3    Adzick, N.S.4    Longaker, M.T.5


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