Hepatoprotective activity of aqueous methanolic extract of Viola odorata against paracetamol-induced liver injury in mice

Bangladesh Journal of Pharmacology

Volumn 9, Issue 2, 2014, Pages 198-202

  Qadir, M Imran ^a   Ali, Muhammad ^a,b   Saleem, Mohammad ^a   Hanif, Muhammad ^b  

^a GC UNIVERSITY   (Pakistan)

^b BAHAUDDIN ZAKARIYA UNIVERSITY   (Pakistan)

Author keywords

Hepatoprotective; Silymarin; Viola odorata

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; ISORHAMNETIN; LIVER PROTECTIVE AGENT; LUTEOLIN; METHANOL; PARACETAMOL; PLANT EXTRACT; SILYMARIN; UNCLASSIFIED DRUG; VIOLA ODORATA EXTRACT; WATER;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; LIVER NECROSIS; LIVER PROTECTION; MOUSE; NONHUMAN; PHYTOCHEMISTRY; TOXIC HEPATITIS; VIOLA ODORATA;

EID: 84899626711     PISSN: 1991007X     EISSN: 19910088     Source Type: Journal    
DOI: 10.3329/bjp.v9i2.18049     Document Type: Article

References (35)

1. Ahmad M, Mahmood Q, Gulzar K, Akhtar MS, Saleem M, Qadir MI. Antihyperlipidaemic and hepatoprotective activity of Dodonaea viscosa leaves extracts in alloxaninduced diabetic rabbits (Oryctolagus cuniculus). Pakistan Vet J. 2012; 32: 50-54.
2. Akhtar MS, Asjad HMM, Bashir S, Malik A, Khalid R, Gulzar F, Irshad N. Evaluation of antioxidant and hepatoprotective effects of Khamira Gaozaban Ambri Jadwar Ood Saleeb Wala (KGA). Bangladesh J Pharmacol. 2013; 8: 44-48.
3. Ali M, Qadir MI, Saleem M, Janbaz KH, Gul H, Hussain L, Ahmed B. Hepatoprotective potential of Convolvulus arvensis against paracetamol-induced hepatotoxicity. Bangladesh J Pharmacol. 2013; 8: 300-04.
4. Amin N, Qadir MI, Khan TJ, Abbas G, Ahmad B, Janbaz KH, Ali M. Antibacterial activity of Vacuum liquid chromatography (VLC) isolated fractions of chloroform extracts of seeds of Achyranthes aspera. J Chem Soc Pak. 2012; 34: 589-92.
5. Amiri MS, Joharchi MR, TaghavizadehYazdi ME. Ethnomedicinal plants used to cure jaundice by traditional healers of Mashhad, Iran. Iranian J Pharm Res. 2014; (Ahead of print)
6. Arora DS, & Kaur GJ. Antibacterial activity of some Indian medicinal plants. Natl Med J. 2007; 61: 313-17.
7. Asif MA, Qadir MI. Molecular approaches for development of malarial vaccines. Rev Pharmacol. 2011; 4: 276-78.
8. Bag AK, Mumtaz SMF. Hepatoprotective and nephroprotective activity of hydroalcoholic extract OfIpomoea staphylina leaves. Bangladesh J Pharmacol. 2013; 8: 263-68.
9. Balamurugan G, Muthusamy P. Observation of the hepatoprotective and antioxidant activities of Trianthema decandra Linn. (Vallai sharunnai) roots on carbon tetrachloridetreated rats. Bangladesh J Pharmacol. 2008; 3: 83-89.
10. Chattopadhyay RR. Possible mechanism of hepatoprotective activity of Azadirachta indica leaf extract. J Ethnopharmacol. 2003; 89: 217-19.
11. Ehsan O, Qadir MI, Malik SA, Abbassi WS, Ahmad B. Efficacy of nanogold-insulin as a hypoglycemic agent. J Chem Soc Pakistan. 2012; 34: 365-70.
12. Hegde K, Joshi AB. Hepatoprotective and antioxidant effect of Carissa spinarum root extract against CCl4 and paracetamolinduced hepatic damage in rats. Bangladesh J Pharmacol. 2010; 5: 73-76.
13. Hussain A, Khalid SH, Qadir MI, Massud A, Ali M, Khan IU, Saleem M, Iqbal MS, Asghar S, Gul H. Water uptake and drug release behaviour of methyl methacrylate-co-itaconic acid [P(MMA/IA)] hydrogels cross-linked with methylene bis-acrylamide. J Drug Deliv Sci Tech. 2011; 21: 249-55.
14. Janbaz KH, Nisar U, Ashraf M, Qadir MI. Spasmolytic, broncho -dilator and antioxidant activities of Erythrina superosa Roxb. Acta Pol Pharm. 2012; 69: 1111-17.
15. Janbaz KH, Saeed SA, Gilani, AH. Studies on the protective effects of caffeic acid and quercetin on chemical-induced hepatotoxicity in rodents. Phytomedicine 2004; 11: 424-30.
16. Javed F, Qadir MI, Janbaz KH, Ali M. Novel drugs from marine microorganisms. Cr Rev Microbiol. 2011; 37: 245-49.
17. Khalid SH, Qadir MI, Massud A, Ali M, Rasool MH. Effect of degree of cross-linking on swelling and drug release behaviour of poly (methyl methacrylate-co-itaconic acid) [P (MMA/IA)] hydrogels for site specific drug delivery. J Drug Deliv Sci Tech. 2009; 19: 413-18.
18. Khan AZ, Mohammad A, Iqbal Z, Anis I, Shah MR, Nadeem S, Rabnawaz M, Shahidullah A, Khan H, Khan I. Molecular docking of viscosine as a new lipoxygenase inhibitor isolated from Dodonaea viscose. Bangladesh J Pharmacol. 2013; 8: 36-39.
19. Khattak SG, Gilani SN, Ikram M. Antipyretic studies on some indigenous Pakistani medicinal plants. J Ethnopharmacol. 1985; 14: 45-51.
20. Koochek M, Pipelzadeh M, Mardani H. The effectiveness of Viola odorata in the prevention and treatment of formalin induced lung damage in the rat. J Herbs Spices Med Plants. 2003; 10: 95-103.
21. Masood MI, Qadir MI, Shirazi JH, Khan IU. Beneficial effects of lactic acid bacteria on human beings. Cr Rev Microbiol. 2011; 37: 91-98.
22. Naz S, Qadir MI, Ali M, Janbaz KH. Nanotechnology for imaging and drug delivery in cancer. J Chem Soc Pakistan. 2011; 34: 107-11.
23. Qadir MI, Malik SA. Anti-diabetic activity of inorganic metals Eugenia jambolana Lam. (Myrtaceae) flowers. Pharmacologyonline. 2010; 2: 979-85.
24. Qadir MI, Malik SA. Effect of Eugenia jambolana leaves extracts on blood glucose levels of experimental diabetic rabbits. Pharmacologyonline. 2009; 3: 829-35.
25. Qadir MI. Medicinal and cosmetological importance of Aloe vera. Int J Nat Ther. 2009; 2: 21-26.
26. Qadir MI. Medicinal values of ginger. Int J Nat Ther. 2009; 3: Qadir MI. Qadirvirtide. Pakistan J Pharm Sci. 2011; 24: 593-95.
27. Sabir SM, Rocha JBT. Antioxidant and hepatoprotective activity of aqueous extract of Solanum fastigiatum against paracetamol- induced liver damage in mice. J Ethnopharmacol. 2008; 120: 226-32.
28. Saboo SS, Tapadiya G, Farooqui IA, Khadabadi SS. Free radical scavenging, in vivo antioxidant and hepatoprotective activity of folk medicine Trichodesma sedgwickianum. Bangladesh J Pharmacol. 2013; 8: 58-64.
29. Saddiqe Z, Naeem I, Maimoona A, Sautreau A, Hellio C. Assay of flavonoid aglycones with HPLC in four species of genus Hypericum. J Med Plants Res. 2011: 5: 1526-30.
30. Sadeque MZ, Begum ZA. Protective effect of dried fruits of Carica papaya on hepatotoxicity in rat. Bangladesh J Pharmacol. 2010; 5: 48-50.
31. Saleem TM, Chetty CM, Ramkanth S, Rajan VST, Kumar KM and Gauthaman K. Hepatoprotective herbs: A review. Int J Res Pharm Sci. 2010; 1: 1-5.
32. Siddiqi HS, Mehmood MH, Rehman NU, Gilani AH. Studies on the antihypertensive and antidyslipidemic activities of Viola odorata leaves extract. Lipids Health Dis. 2012; 11: 6.
33. Singab ANB, Youssef DT, Noaman E, Kotb S. Hepatoprotective effect of flavonol glycosides rich fraction from Egyptian Vicia calcarata desf. Against CCI4-induced liver damage in rats. Arch Pharmacal Res. 2005; 28: 791-98.
34. Thakare SP, Jain HN, Patil SD, Upadhyay UM. Hepatoprotective effect of Cocculus hirsutus on bile duct ligation-induced liver fibrosis in albino Wistar rats. Bangladesh J Pharmacol. 2009; 4: 126-30.
35. Vadivu R, Lakshmi KS. In vitro and in vivo anti-inflammatory activity of leaves of Symplocos cochinchnensis (Lour) Moore ssp laurina. Bangladesh J Pharmacol. 2008; 3: 121-24.