Hepatoprotective and nephroprotective activity of hydroalcoholic extract of ipomoea staphylina leaves

Bangladesh Journal of Pharmacology

Volumn 8, Issue 3, 2013, Pages 263-268

  Kanti Bag, Anupam ^a   Firdous Mumtaz, S M ^b  

^a Ratnam Institute of Pharmacy   (India)

^b Calcutta Institute of Pharmaceutical Technology and AHS   (India)

Author keywords

Carbon tetrachloride; Gentamicin; Ipomoea staphylina; Nephrotoxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBON TETRACHLORIDE; CREATININE; GALLIC ACID; GENTAMICIN; IPOMOEA STAPHYLINA EXTRACT; PLANT EXTRACT; SILYMARIN; UNCLASSIFIED DRUG; UREA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; BLOOD SAMPLING; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG EFFICACY; FEMALE; HISTOLOGY; IPOMOEA; IPOMOEA STAPHYLINA; LIVER PROTECTION; LIVER TOXICITY; MALE; NEPHROTOXICITY; NONHUMAN; PLANT LEAF; PROTEIN BLOOD LEVEL; RAT; RENAL PROTECTION; SINGLE DRUG DOSE; TREATMENT RESPONSE; UREA BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL;

EID: 84878510222     PISSN: 1991007X     EISSN: 19910088     Source Type: Journal    
DOI: 10.3329/bjp.v8i3.14845     Document Type: Article

References (19)

1. AL-Howiriny TA, AL-Sohaibani MO, AL-Said MS, Rafatullah S. Hepatoprotective properties of Commiphora opobalsamum (Balessan), a traditional medicinal plant of Saudi Arabia. Drugs Exp Clin. 2004; 30: 213-20.
2. Firdous M, Nitesh SC. Evaluation of antiulcer activity of Ipomoea staphylina. Pharmacologyonline 2009; 3: 195-99.
3. Firdous SM, Raju K. In vivo and in vitro antiinflammatory activity of leaves of Ipomoea staphylina. Int J Pharm Pharm Sci. 2012; 4: 339-43.
4. Firdous SM, Raju K, Pallab H. Evaluation of hepatoprotective activity of saponin of Momordica dioica roxb. Against CCl4 induced hepatic injury in rats. Pharmacologyonline. 2008; 3: 487-94.
5. Harlalka GV, Patil CR, Patil MR. Protective effect of Kalanchoe pinnata pers. (crassulaceae) on gentamicin-induced nephrotoxicity in rats. Indian J Pharmacol. 2007; 39: 201-05.
6. Kaplowitz N, Aw TY, Simon FR, Stolz A. Drug induced hepatotoxicity. Ann Intern Med. 1986; 104: 826.
7. Kim DO, Jeong SW, Lee CY: Antioxidant capacity of phenolic phytochemicals from various cultivars of plums. Food Chem. 2003; 81: 321-26.
8. Krishna BKL, Mruthunjaya K, Patel JA. Antioxidant and hepatoprotective activity of leaf extract of Justica gendrerussa. Int J Biol Chem. 2009; 3: 99-110.
9. Levey AS, Atkins R, Coresh J, Cohen EP, Collins AJ, Eckardt KU, Nahas ME, Jaber BL, Jadoul M, Levin A, Powe N R, Rossert J, Wheeler DC, Lameire N, Eknoyan G. Chronic kidney disease as a global public health problem: Approaches and initiatives - a position statement from Kidney Disease Improving Global Outcomes. Kidney Int. 2007; 10: 1-5.
10. Manokaran S, Jaswanth A, Sengottuvelu S, Nandhakumar J. Hepatoprotective activity of Aerva lanata Linn. against Paracetamol induced hepatotoxicity in rats. Res J Pharm Tech. 2008; 1: 398-400.
11. OECD, 2002. Acute oral toxicity. Acute oral toxic class method guideline 423 adopted 23.03.1996. In: Eleventh Addendum to the, OECD, guidelines for the testing of chemicals organisation for economics co-operation, development, Paris, June, 2000, p 11.
12. Park YS, Jung ST, Kang SG, Heo BK, Arancibia-Avila P, Toledo F, Drzewiecki J, Namiesnik J, Gorinstein S. Antioxidants and proteins in ethylene-treated kiwifruits. Food Chem. 2008; 107: 640-48.
13. Poormoosavi SM, Behmanesh MA, Najafzadeh H. Effect of cimetidine on gentamicin-losartan induced-nephrotoxicity in rats. Afr J Pharm Pharmacol. 2010; 4: 341-45.
14. Punitha ISR, Shirwaikar A, Shirwaikar A. Antidiabetic activity of benzyltetraisoquinoline alkaloid berberine in streptozotocin nicotinamide induced type 2 diabetic rats. Diabetologia Croatica. 2005; 34: 117-28.
15. Saleem TSM, Chetty SM, Ramkanth S, Rajan VST, Kumar KM, Gauthaman K. Hepatoprotective herbs: A review. Int J Res Pharm Sci. 2010; 1: 1-5.
16. Sanjay J, Vinod KD, Neelzesh M, Vijay A. Antioxidant and hepatopraotective activity of hydroalcoholic and aqueous extracts of Amorphophallus campanulatus roxb. tubers. Acta Poloniac Pharm Drug Res. 2009; 66: 423-28.
17. Rajib A, Monirul I, Israt JB. Hepatoprotective activity of methanol extract of some medicinal plants against carbon tetrachloride-induced hepatotoxicity in rats. Eur J Sci Res. 2009; 37: 302-10.
18. Reddy DP, Kota R, Renuka S, Anarthe SJ, Nulgumnall, Manjunathaiah R, Isolation, characterization of phytoconstituents and pharmacological screening of Ipomoea staphylina. Asian J Pharm Clin Res. 2013; 6: 30-33.
19. Wahid AM, Vijay RS, Satish BB. Hepatoprotective activity of hydroalcoholic extract leaves of Alocassie indica. Indian J Exp Biol. 2009; 47: 816-21.