-
1
-
-
48249087666
-
Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells
-
Akar U., Chaves-Reyez A., Barria M., Tari A., Sanguino A., Kondo Y., Kondo S., Arun B., Lopez-Berestein G., Ozpolat B. Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells. Autophagy 2008, 4:669-679.
-
(2008)
Autophagy
, vol.4
, pp. 669-679
-
-
Akar, U.1
Chaves-Reyez, A.2
Barria, M.3
Tari, A.4
Sanguino, A.5
Kondo, Y.6
Kondo, S.7
Arun, B.8
Lopez-Berestein, G.9
Ozpolat, B.10
-
2
-
-
79951847989
-
Principles and current strategies for targeting autophagy for cancer treatment
-
Amaravadi R.K., Lippincott-Schwartz J., Yin X.M., Weiss W.A., Takebe N., Timmer W., DiPaola R.S., Lotze M.T., White E. Principles and current strategies for targeting autophagy for cancer treatment. Clin. Cancer Res. 2011, 17:654-666.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 654-666
-
-
Amaravadi, R.K.1
Lippincott-Schwartz, J.2
Yin, X.M.3
Weiss, W.A.4
Takebe, N.5
Timmer, W.6
DiPaola, R.S.7
Lotze, M.T.8
White, E.9
-
3
-
-
18544387911
-
Prolactin inhibits apoptosis of ovarian carcinoma cellsinduced by serum starvation or cisplatin treatment
-
Asai-Sato M., Nagashima Y., Miyagi E., Sato K., Ohta I., Vonderhaar B.K., Hirahara F. Prolactin inhibits apoptosis of ovarian carcinoma cellsinduced by serum starvation or cisplatin treatment. Int. J. Cancer 2005, 115:539-544.
-
(2005)
Int. J. Cancer
, vol.115
, pp. 539-544
-
-
Asai-Sato, M.1
Nagashima, Y.2
Miyagi, E.3
Sato, K.4
Ohta, I.5
Vonderhaar, B.K.6
Hirahara, F.7
-
4
-
-
56449116341
-
PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival
-
Bartholomeusz C., Rosen D., Wei C., Kazansky A., Yamasaki F., Takahashi T., Itamochi H., Kondo S., Liu J., Ueno N.T. PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival. Cancer Res. 2008, 68:9302-9310.
-
(2008)
Cancer Res.
, vol.68
, pp. 9302-9310
-
-
Bartholomeusz, C.1
Rosen, D.2
Wei, C.3
Kazansky, A.4
Yamasaki, F.5
Takahashi, T.6
Itamochi, H.7
Kondo, S.8
Liu, J.9
Ueno, N.T.10
-
5
-
-
77949748262
-
PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase
-
Bartholomeusz C., Gonzalez-Angulo A.M., Kazansky A., Krishnamurthy S., Liu P., Yuan L.X., Yamasaki F., Liu S., Hayashi N., Zhang D., et al. PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase. Clin. Cancer Res. 2010, 16:1802-1811.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 1802-1811
-
-
Bartholomeusz, C.1
Gonzalez-Angulo, A.M.2
Kazansky, A.3
Krishnamurthy, S.4
Liu, P.5
Yuan, L.X.6
Yamasaki, F.7
Liu, S.8
Hayashi, N.9
Zhang, D.10
-
6
-
-
0029741890
-
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy
-
Bursch W., Ellinger A., Kienzl H., Török L., Pandey S., Sikorska M., Walker R., Hermann R.S. Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis 1996, 17:1595-1607.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1595-1607
-
-
Bursch, W.1
Ellinger, A.2
Kienzl, H.3
Török, L.4
Pandey, S.5
Sikorska, M.6
Walker, R.7
Hermann, R.S.8
-
7
-
-
77955865105
-
Inhibition of PI3k class III-dependent autophagy prevents apoptosis and necrosis by oxidative stress in dopaminergic neuroblastoma cells
-
Castino R., Bellio N., Follo C., Murphy D., Isidoro C. Inhibition of PI3k class III-dependent autophagy prevents apoptosis and necrosis by oxidative stress in dopaminergic neuroblastoma cells. Toxicol. Sci. 2010, 117:152-162.
-
(2010)
Toxicol. Sci.
, vol.117
, pp. 152-162
-
-
Castino, R.1
Bellio, N.2
Follo, C.3
Murphy, D.4
Isidoro, C.5
-
8
-
-
0025826725
-
Prolactin activates protein kinase C and stimulates growth-related gene expression in rat liver
-
Crowe P.D., Buckley A.R., Zorn N.E., Rui H. Prolactin activates protein kinase C and stimulates growth-related gene expression in rat liver. Mol. Cell. Endocrinol. 1991, 79:29-35.
-
(1991)
Mol. Cell. Endocrinol.
, vol.79
, pp. 29-35
-
-
Crowe, P.D.1
Buckley, A.R.2
Zorn, N.E.3
Rui, H.4
-
9
-
-
0036827922
-
Pituitary tumorigenesis in prolactin gene-disrupted mice
-
Cruz-Soto M.E., Scheiber M.D., Gregerson K.A., Boivin G.P., Horseman N.D. Pituitary tumorigenesis in prolactin gene-disrupted mice. Endocrinology 2002, 143:4429-4436.
-
(2002)
Endocrinology
, vol.143
, pp. 4429-4436
-
-
Cruz-Soto, M.E.1
Scheiber, M.D.2
Gregerson, K.A.3
Boivin, G.P.4
Horseman, N.D.5
-
10
-
-
77953699668
-
Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer
-
Dalby K.N., Tekedereli I., Lopez-Berestein G., Ozpolat B. Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer. Autophagy 2010, 6:322-329.
-
(2010)
Autophagy
, vol.6
, pp. 322-329
-
-
Dalby, K.N.1
Tekedereli, I.2
Lopez-Berestein, G.3
Ozpolat, B.4
-
11
-
-
25444443688
-
Modelling glandular epithelial cancers in three-dimensional cultures
-
Debnath J., Brugge J.S. Modelling glandular epithelial cancers in three-dimensional cultures. Nat. Rev. Cancer 2005, 5:675-688.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 675-688
-
-
Debnath, J.1
Brugge, J.S.2
-
12
-
-
34248591497
-
Calpain as a novel regulator of autophagosome formation
-
Demarchi F., Bertoli C., Copetti T., Eskelinen E.L., Schneider C. Calpain as a novel regulator of autophagosome formation. Autophagy 2007, 3:235-237.
-
(2007)
Autophagy
, vol.3
, pp. 235-237
-
-
Demarchi, F.1
Bertoli, C.2
Copetti, T.3
Eskelinen, E.L.4
Schneider, C.5
-
13
-
-
77951750296
-
Selective autophagy in cancer development and therapy
-
Dikic I., Johansen T., Kirkin V. Selective autophagy in cancer development and therapy. Cancer Res. 2010, 70:3431-3434.
-
(2010)
Cancer Res.
, vol.70
, pp. 3431-3434
-
-
Dikic, I.1
Johansen, T.2
Kirkin, V.3
-
14
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He T.C., Zhou S., da Costa L.T., Yu J., Kinzler K.W., Vogelstein B. A simplified system for generating recombinant adenoviruses. Proc. Natl. Acad. Sci. USA 1998, 95:2509-2514.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
15
-
-
34548077575
-
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
-
Kimura S., Noda T., Yoshimori T. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 2007, 3:452-460.
-
(2007)
Autophagy
, vol.3
, pp. 452-460
-
-
Kimura, S.1
Noda, T.2
Yoshimori, T.3
-
16
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
Klionsky D.J., Abdalla F.C., Abeliovich H., Abraham R.T., Acevedo-Arozena A., Adeli K., Agholme L., Agnello M., Agostinis P., Aguirre-Ghiso J.A., et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012, 8:445-544.
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
Abraham, R.T.4
Acevedo-Arozena, A.5
Adeli, K.6
Agholme, L.7
Agnello, M.8
Agostinis, P.9
Aguirre-Ghiso, J.A.10
-
17
-
-
0031819445
-
Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II invitro
-
Kubes M., Cordier J., Glowinski J., Girault J.A., Chneiweiss H. Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II invitro. J.Neurochem. 1998, 71:1307-1314.
-
(1998)
J.Neurochem.
, vol.71
, pp. 1307-1314
-
-
Kubes, M.1
Cordier, J.2
Glowinski, J.3
Girault, J.A.4
Chneiweiss, H.5
-
18
-
-
67449164593
-
Biological significance of prolactin in gynecologic cancers
-
Levina V.V., Nolen B., Su Y., Godwin A.K., Fishman D., Liu J., Mor G., Maxwell L.G., Herberman R.B., Szczepanski M.J., et al. Biological significance of prolactin in gynecologic cancers. Cancer Res. 2009, 69:5226-5233.
-
(2009)
Cancer Res.
, vol.69
, pp. 5226-5233
-
-
Levina, V.V.1
Nolen, B.2
Su, Y.3
Godwin, A.K.4
Fishman, D.5
Liu, J.6
Mor, G.7
Maxwell, L.G.8
Herberman, R.B.9
Szczepanski, M.J.10
-
19
-
-
48249092267
-
Bcl-2 family members: dual regulators of apoptosis and autophagy
-
Levine B., Sinha S., Kroemer G. Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 2008, 4:600-606.
-
(2008)
Autophagy
, vol.4
, pp. 600-606
-
-
Levine, B.1
Sinha, S.2
Kroemer, G.3
-
20
-
-
84857651643
-
Optimizing a 3D Culture System to Study the Interaction between Epithelial Breast Cancer and Its Surrounding Fibroblasts
-
Li L., Lu Y. Optimizing a 3D Culture System to Study the Interaction between Epithelial Breast Cancer and Its Surrounding Fibroblasts. J.Cancer 2011, 2:458-466.
-
(2011)
J.Cancer
, vol.2
, pp. 458-466
-
-
Li, L.1
Lu, Y.2
-
21
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang X.H., Jackson S., Seaman M., Brown K., Kempkes B., Hibshoosh H., Levine B. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999, 402:672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
22
-
-
0034726953
-
Human prolactin (hPRL) antagonists inhibit hPRL-activated signaling pathways involved in breast cancer cell proliferation
-
Llovera M., Pichard C., Bernichtein S., Jeay S., Touraine P., Kelly P.A., Goffin V. Human prolactin (hPRL) antagonists inhibit hPRL-activated signaling pathways involved in breast cancer cell proliferation. Oncogene 2000, 19:4695-4705.
-
(2000)
Oncogene
, vol.19
, pp. 4695-4705
-
-
Llovera, M.1
Pichard, C.2
Bernichtein, S.3
Jeay, S.4
Touraine, P.5
Kelly, P.A.6
Goffin, V.7
-
24
-
-
77956509404
-
Lipopolysaccharide induces autophagy through BIRC2 in human umbilical vein endothelial cells
-
Meng N., Wu L., Gao J., Zhao J., Su L., Su H., Zhang S., Miao J. Lipopolysaccharide induces autophagy through BIRC2 in human umbilical vein endothelial cells. J.Cell. Physiol. 2010, 225:174-179.
-
(2010)
J.Cell. Physiol.
, vol.225
, pp. 174-179
-
-
Meng, N.1
Wu, L.2
Gao, J.3
Zhao, J.4
Su, L.5
Su, H.6
Zhang, S.7
Miao, J.8
-
25
-
-
19644388098
-
Serum protein markers for early detection of ovarian cancer
-
Mor G., Visintin I., Lai Y., Zhao H., Schwartz P., Rutherford T., Yue L., Bray-Ward P., Ward D.C. Serum protein markers for early detection of ovarian cancer. Proc. Natl. Acad. Sci. USA 2005, 102:7677-7682.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 7677-7682
-
-
Mor, G.1
Visintin, I.2
Lai, Y.3
Zhao, H.4
Schwartz, P.5
Rutherford, T.6
Yue, L.7
Bray-Ward, P.8
Ward, D.C.9
-
26
-
-
77957683915
-
Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore
-
Quinsay M.N., Thomas R.L., Lee Y., Gustafsson A.B. Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore. Autophagy 2010, 6:855-862.
-
(2010)
Autophagy
, vol.6
, pp. 855-862
-
-
Quinsay, M.N.1
Thomas, R.L.2
Lee, Y.3
Gustafsson, A.B.4
-
27
-
-
33947719279
-
Potential therapeutic applications of autophagy
-
Rubinsztein D.C., Gestwicki J.E., Murphy L.O., Klionsky D.J. Potential therapeutic applications of autophagy. Nat. Rev. Drug Discov. 2007, 6:304-312.
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 304-312
-
-
Rubinsztein, D.C.1
Gestwicki, J.E.2
Murphy, L.O.3
Klionsky, D.J.4
-
28
-
-
0027941433
-
Activation of receptor-associated tyrosine kinase JAK2 by prolactin
-
Rui H., Kirken R.A., Farrar W.L. Activation of receptor-associated tyrosine kinase JAK2 by prolactin. J.Biol. Chem. 1994, 269:5364-5368.
-
(1994)
J.Biol. Chem.
, vol.269
, pp. 5364-5368
-
-
Rui, H.1
Kirken, R.A.2
Farrar, W.L.3
-
29
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
-
Shimizu S., Kanaseki T., Mizushima N., Mizuta T., Arakawa-Kobayashi S., Thompson C.B., Tsujimoto Y. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat. Cell Biol. 2004, 6:1221-1228.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
Mizuta, T.4
Arakawa-Kobayashi, S.5
Thompson, C.B.6
Tsujimoto, Y.7
-
30
-
-
84863808329
-
Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter
-
Sulzmaier F., Opoku-Ansah J., Ramos J.W. Phosphorylation is the switch that turns PEA-15 from tumor suppressor to tumor promoter. Small GTPases 2012, 3:173-177.
-
(2012)
Small GTPases
, vol.3
, pp. 173-177
-
-
Sulzmaier, F.1
Opoku-Ansah, J.2
Ramos, J.W.3
-
31
-
-
79961128105
-
Prolactin increases survival and migration of ovarian cancer cells: importance of prolactin receptor type and therapeutic potential of S179D and G129R receptor antagonists
-
Tan D., Chen K.E., Khoo T., Walker A.M. Prolactin increases survival and migration of ovarian cancer cells: importance of prolactin receptor type and therapeutic potential of S179D and G129R receptor antagonists. Cancer Lett. 2011, 310:101-108.
-
(2011)
Cancer Lett.
, vol.310
, pp. 101-108
-
-
Tan, D.1
Chen, K.E.2
Khoo, T.3
Walker, A.M.4
-
32
-
-
0038721240
-
Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action
-
Trencia A., Perfetti A., Cassese A., Vigliotta G., Miele C., Oriente F., Santopietro S., Giacco F., Condorelli G., Formisano P., Beguinot F. Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action. Mol. Cell. Biol. 2003, 23:4511-4521.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4511-4521
-
-
Trencia, A.1
Perfetti, A.2
Cassese, A.3
Vigliotta, G.4
Miele, C.5
Oriente, F.6
Santopietro, S.7
Giacco, F.8
Condorelli, G.9
Formisano, P.10
Beguinot, F.11
-
33
-
-
0034255393
-
Lyophilization and development of solid protein pharmaceuticals
-
Wang W. Lyophilization and development of solid protein pharmaceuticals. Int. J. Pharm. 2000, 203:1-60.
-
(2000)
Int. J. Pharm.
, vol.203
, pp. 1-60
-
-
Wang, W.1
-
34
-
-
77951220669
-
Role of autophagy in suppression of inflammation and cancer
-
White E., Karp C., Strohecker A.M., Guo Y., Mathew R. Role of autophagy in suppression of inflammation and cancer. Curr. Opin. Cell Biol. 2010, 22:212-217.
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 212-217
-
-
White, E.1
Karp, C.2
Strohecker, A.M.3
Guo, Y.4
Mathew, R.5
-
35
-
-
0037134424
-
Role of tyrosine kinase Jak2 in prolactin-induced differentiation and growth of mammary epithelial cells
-
Xie J., LeBaron M.J., Nevalainen M.T., Rui H. Role of tyrosine kinase Jak2 in prolactin-induced differentiation and growth of mammary epithelial cells. J.Biol. Chem. 2002, 277:14020-14030.
-
(2002)
J.Biol. Chem.
, vol.277
, pp. 14020-14030
-
-
Xie, J.1
LeBaron, M.J.2
Nevalainen, M.T.3
Rui, H.4
-
36
-
-
79953754929
-
Growth hormone signaling in human T47D breast cancer cells: potential role for a growth hormone receptor-prolactin receptor complex
-
Xu J., Zhang Y., Berry P.A., Jiang J., Lobie P.E., Langenheim J.F., Chen W.Y., Frank S.J. Growth hormone signaling in human T47D breast cancer cells: potential role for a growth hormone receptor-prolactin receptor complex. Mol. Endocrinol. 2011, 25:597-610.
-
(2011)
Mol. Endocrinol.
, vol.25
, pp. 597-610
-
-
Xu, J.1
Zhang, Y.2
Berry, P.A.3
Jiang, J.4
Lobie, P.E.5
Langenheim, J.F.6
Chen, W.Y.7
Frank, S.J.8
-
37
-
-
0031593675
-
Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells
-
Yamamoto A., Tagawa Y., Yoshimori T., Moriyama Y., Masaki R., Tashiro Y. Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells. Cell Struct. Funct. 1998, 23:33-42.
-
(1998)
Cell Struct. Funct.
, vol.23
, pp. 33-42
-
-
Yamamoto, A.1
Tagawa, Y.2
Yoshimori, T.3
Moriyama, Y.4
Masaki, R.5
Tashiro, Y.6
-
38
-
-
2642553881
-
Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8
-
Yu L., Alva A., Su H., Dutt P., Freundt E., Welsh S., Baehrecke E.H., Lenardo M.J. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004, 304:1500-1502.
-
(2004)
Science
, vol.304
, pp. 1500-1502
-
-
Yu, L.1
Alva, A.2
Su, H.3
Dutt, P.4
Freundt, E.5
Welsh, S.6
Baehrecke, E.H.7
Lenardo, M.J.8
|