Influenza viral vectors expressing the Brucella OMP16 or L7/L12 proteins as vaccines against B. abortus infection

Virology Journal

Volumn 11, Issue 1, 2014, Pages

  Tabynov, Kaissar ^a   Sansyzbay, Abylai ^a   Kydyrbayev, Zhailaubay ^a   Yespembetov, Bolat ^a   Ryskeldinova, Sholpan ^a   Zinina, Nadezhda ^a   Assanzhanova, Nurika ^a   Sultankulova, Kulaisan ^a   Sandybayev, Nurlan ^a   Khairullin, Berik ^a   Kuznetsova, Irina ^b   Ferko, Boris ^b   Egorov, Andrej ^b  

^a The Research Institute for Biological Safety Problems   (Kazakhstan)

^b HSC Development GmbH   (Austria)

Author keywords

B. abortus infection; Influenza virus; L7 L12; OMP16; Vaccine; Vector

Indexed keywords

BACTERIAL PROTEIN; BRUCELLA VACCINE; NONSTRUCTURAL PROTEIN 1; OUTER MEMBRANE PROTEIN 16; RIBOSOMAL PROTEIN L7 L12; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; BRUCELLOSIS; CHICKEN; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; GENE REPLICATION; GUINEA PIG; IMMUNE RESPONSE; IMMUNOGENICITY; INFLUENZA A (H5N1); INFLUENZA VIRUS A; INFLUENZA VIRUS A H1N1; MOUSE; NONHUMAN; PHENOTYPE; REVERSE GENETICS; T LYMPHOCYTE; UPPER RESPIRATORY TRACT; WEIGHT REDUCTION;

ANIMALIA; BRUCELLA; BRUCELLA MELITENSIS BIOVAR ABORTUS; CAVIA; MUS; ORTHOMYXOVIRIDAE;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; BRUCELLA ABORTUS; BRUCELLA VACCINE; BRUCELLOSIS; DISEASE MODELS, ANIMAL; DRUG CARRIERS; GENETIC VECTORS; GENOMIC INSTABILITY; GUINEA PIGS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; MICE; RIBOSOMAL PROTEINS; SURVIVAL ANALYSIS; T-LYMPHOCYTES; VACCINATION; VACCINES, SYNTHETIC; VIRUS REPLICATION;

EID: 84899586125     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-11-69     Document Type: Article

References (51)

1. From the discovery of the Malta fever's agent to the discovery of a marine mammal reservoir, brucellosis has continuously been a re-emerging zoonosis. Godfroid J, Cloeckaert A, Liautard JP, Kohler S, Fretin D, Walravens K, Garin-Bastuji B, Letesson JJ, Vet Res 2005 36 313 326 10.1051/vetres:2005003 15845228 (Pubitemid 40716368)
2. Brucellosis vaccines: past, present and future. Schurig GG, Sriranganathan N, Corbel MJ, Vet Microbiol 2002 90 479 496 10.1016/S0378- 1135(02)00255-9 12414166 (Pubitemid 35282500)
3. Adverse events in humans associated with accidental exposure to the livestock brucellosis vaccine RB51. Ashford DA, di Pietra J, Lingappa J, Woods C, Noll H, Neville B, Weyant R, Bragg SL, Spiegel RA, Tappero J, Perkins BA, Vaccine 2004 22 3435 3439 10.1016/j.vaccine.2004.02.041 15308369 (Pubitemid 39089100)
4. Effects of cytokines on intracellular growth of Brucella abortus. Jiang X, Baldwin CL, Infect Immun 1993 61 124 134 8418034 (Pubitemid 23015408)
5. + type 1 CD44hi CD45 RBloT lymphocytes control intracellular Brucella abortus infection as demonstrated in major histocompatibility complex class I- and class II-deficient mice. Oliveira SC, Splitter GA, Eur J Immunol 1995 25 2551 2557 10.1002/eji.1830250922 7589125
6. Protection of BALB/c mice against Brucella abortus 544 challenge by vaccination with bacterioferritin or P39 recombinant proteins with CpGoligodeoxynucleotides as adjuvant. Al-Mariri A, Tibor A, Mertens P, De Bolle X, Michel P, Godefroid J, Walravens K, Letesson JJ, Infect Immun 2001 69 4816 4822 10.1128/IAI.69.8.4816-4822.2001 11447155 (Pubitemid 32674460)
7. Modulation of immune responses in Balb/c mice vaccinated with Brucellaabortus Cu-Zn superoxide dismutase synthetic peptide vaccine. Tabatabai LB, Pugh GW Jr, Vaccine 1994 12 919 924 10.1016/0264-410X(94)90035-3 7526568
8. Immunization of mice with recombinant L7/L12 ribosomal protein confers protection against Brucella abortus infection. Oliveira SC, Splitter GA, Vaccine 1996 14 959 962 10.1016/0264-410X(96)00018-7 8873388 (Pubitemid 26271067)
9. Sequences of the rplJL operon containing the L10 and L7/L12 genes from Brucella abortus. Oliveira SC, Zhu Y, Splitter G, Gene 1994 140 137 138 10.1016/0378-1119(94)90744-7 8125331 (Pubitemid 24082390)
10. Recombinant L7/L12 ribosomal protein and gamma-irradiated Brucella abortus induce a T-helper 1 subset response from murine CD4+ T cells. Oliveira SC, Zhu Y, Splitter GA, Immunology 1994 83 659 664 7875746 (Pubitemid 24374102)
11. Recombinant Brucella abortus proteins that induce proliferation and gamma-interferon secretion by CD4+ T cells from Brucella-vaccinated mice and delayed-type hypersensitivity in sensitized guinea pigs. Oliveira SC, Harms JS, Banai M, Splitter GA, Cell Immunol 1996 172 262 268 10.1006/cimm.1996.0241 8964089 (Pubitemid 26319784)
12. Vaccination with the recombinant Brucella outer membrane protein 31 or a derived 27-amino-acid synthetic peptide elicits a CD4+ T helper 1 response that protects against Brucella melitensis infection. Cassataro J, Estein SM, Pasquevich KA, Velikovsky CA, de laBarrera S, Bowden R, Fossati CA, Giambartolomei GH, Infect Immun 2005 73 8079 8088 10.1128/IAI.73.12.8079-8088. 2005 16299302 (Pubitemid 41740295)
13. Immunization with recombinant Brucella species outer membrane protein Omp16 or Omp19 in adjuvant induces specific CD4+ and CD8+ T cells as well as systemic and oral protection against Brucella abortus infection. Pasquevich KA, Estein SM, García Samartino C, Zwerdling A, Coria LM, Barrionuevo P, Fossati CA, Giambartolomei GH, Cassataro J, Infect Immun 2009 77 436 445 10.1128/IAI.01151-08 18981242
14. Liposomised recombinant ribosomal L7/L12 protein protects BALB/c mice against Brucella abortus 544 infection. Mallick AI, Singha H, Chaudhuri P, Nadeem A, Khan SA, Dar KA, Owais M, Vaccine 2007 25 3692 3704 10.1016/j.vaccine.2007.01.066 17296251 (Pubitemid 46584754)
15. Enhanced efficacy of DNA vaccines against an intracellular bacterial pathogen by genetic adjuvants. Leclercq S, Harms JS, Oliveira SC, Curr Pharm Biotechnol 2003 4 99 107 10.2174/1389201033489892 12678885 (Pubitemid 36416867)
16. Nucleic acid vaccination of Brucella abortus ribosomal L7/L12 gene elicits immune response. Kurar E, Splitter GA, Vaccine 1997 15 1851 1857 10.1016/S0264-410X(97)00140-0 9413093 (Pubitemid 27504679)
17. A DNA vaccine encoding Cu, Zn superoxide dismutase of Brucella abortus induces protective immunity in BALB/c mice. Oñate AA, Céspedes S, Cabrera A, Rivers R, González A, Muñoz C, Folch H, Andrews E, Infect Immun 2003 71 4857 4861 10.1128/IAI.71.9.4857-4861.2003 12933826 (Pubitemid 37070726)
18. The cloning, expression, and nucleotide sequence of a gene coding for an immunogenic Brucella abortus protein. Mayfield JE, Bricker BJ, Godfrey H, Crosby RM, Knight DJ, Halling SM, Balinsky D, Tabatabai LB, Gene 1988 63 1 9 10.1016/0378-1119(88)90540-9 3133283 (Pubitemid 18082124)
19. A DNA vaccine coding for the Brucella outer membrane protein 31 confers protection against B. melitensis and B. ovis infection by eliciting a specific cytotoxic response. Cassataro J, Velikovsky CA, de la Barrera S, Estein SM, Bruno L, Bowden R, Pasquevich KA, Fossati CA, Giambartolomei GH, Infect Immun 2005 73 6537 6546 10.1128/IAI.73.10.6537-6546.2005 16177328 (Pubitemid 41368818)
20. Protective immunity elicited by a divalent DNA vaccine encoding both the L7/L12 and Omp16 genes of Brucella abortus in BALB/c mice. Luo D, Ni B, Li P, Shi W, Zhang S, Han Y, Mao L, He Y, Wu Y, Wang X, Infect Immun 2006 74 2734 2741 10.1128/IAI.74.5.2734-2741.2006 16622210 (Pubitemid 43672982)
21. Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen. Harms JS, Durward MA, Magnani DM, Splitter GA, J Immune Based Ther Vaccines 2009 7 1 doi:10.1186/1476-8518-7- 1 10.1186/1476-8518-7-1 19126207
22. Protection of mice from Brucella infection by immunization with attenuated Salmonella enteric serovar typhimurium expressing A L7/L12 and BLS fusion antigen of Brucella. Zhao Z, Li M, Luo D, Xing L, Wu S, Duan Y, Yang P, Wang X, Vaccine 2009 27 5214 5219 10.1016/j.vaccine.2009.06.075 19596411
23. Recombinant Ochrobactrum anthropi Expressing Brucella abortus Cu, Zn Superoxide Dismutase Protects Mice against B. abortus Infection Only after Switching of Immune Responses to Th1 Type. He Y, Vemulapalli R, Schurig GG, Infect Immun 2002 70 5 2535 2543 10.1128/IAI.70.5.2535-2543.2002 11953393 (Pubitemid 34408398)
24. Vaccination with recombinant Semliki Forest virus particles expressing translation initiation factor 3 of Brucella abortus induces protective immunity in BALB/c mice. Cabrera A, Sáez D, Céspedes S, Andrews E, Oñate A, Immunobiology 2009 214 6 467 474 10.1016/j.imbio.2008.11.016 19150742
25. Generation of influenza A viruses entirely from cloned cDNAs. Neumann G, Watanabe T, Ito H, Watanabe S, Goto H, Gao P, Hughes M, Perez DR, Donis R, Hoffmann E, Hobom G, Kawaoka Y, Proc Natl Acad Sci U S A 1999 96 9345 9350 10.1073/pnas.96.16.9345 10430945 (Pubitemid 29374757)
26. A plasmid-based reverse genetics system for influenza A virus. Pleschka S, Jaskunas R, Engelhardt OG, Zurcher T, Palese P, Garcia-Sastre A, J Virol 1996 70 4188 4192 8648766 (Pubitemid 26157406)
27. Rescue of influenza virus expressing GFP from the NS1 reading frame. Kittel C, Sereinig S, Ferko B, Stasakova J, Romanova J, Wolkerstorfer A, Katinger H, Egorov A, Virology 2004 324 67 73 10.1016/j.virol.2004.03.035 15183054 (Pubitemid 38737400)
28. Laboratory Animal Models for Brucellosis Research. Silva TMA, Costa EA, Paixao TA, Tsolis RM, Santos RL, J Biomed Biotechnol 2011 2011 518323 21403904
29. The duration of bacteraemia in relation to the virulence of Brucella strains. Cruickshank JC, J Hyg (Lond) 1957 55 1 140 147 10.1017/ S0022172400061313 13416580
30. Mucosal delivery of vaccines in domestic animals. Gerdts V, Mutwiri GK, Tikoo SK, Babiuk LA, Vet Res 2006 37 487 510 10.1051/vetres:2006012 16611560 (Pubitemid 43725033)
31. Strains of Hong Kong influenza virus in calves. Campbell CH, Easterday BC, Webster RG, J Infect Dis 1977 135 678 680 10.1093/infdis/135.4.678 853249 (Pubitemid 8085936)
32. Detection of antibodies to influenza A virus in cattle in association with respiratory disease and reduced milk yield. Brown IH, Crawshaw TR, Harris PA, Alexander DJ, Vet Rec 1998 143 637 638 9881443 (Pubitemid 128489893)
33. Evidence of influenza A virus infection in dairy cows with sporadic milk drop syndrome. Gunning RF, Brown IH, Crawshaw TR, Vet Rec 1999 145 556 557 10.1136/vr.145.19.556 10609575 (Pubitemid 129540050)
34. Retrospective analysis of serum and nasal mucus from cattle in Northern Ireland for evidence of infection with influenza A virus. Graham DA, Calvert V, McLaren E, Vet Rec 2002 150 201 204 10.1136/vr.150.7.201 11878437 (Pubitemid 34173401)
35. Influenza virus NS Vectors expressing the mycobacterium tuberculosis ESAT-6 Protein Induce CD4+ Th1 immune response and protect animals against tuberculosis challenge. Sereinig S, Stukova M, Zabolotnyh N, Ferko B, Kittel C, Romanova J, Vinogradova T, Katinger H, Kiselev O, Egorov A, Clin Vaccine Immunol 2006 13 8 898 904 10.1128/CVI.00056-06 16893990 (Pubitemid 44409629)
36. Hyperattenuated recombinant influenza A virus nonstructural-protein- encoding vectors induce human immunodeficiency virus type 1 Nef-specific systemic and mucosal immune responses in mice. Ferko B, Stasakova J, Sereinig S, Romanova J, Katinger D, Niebler B, Katinger H, Egorov A, J Virol 2001 75 8899 8908 10.1128/JVI.75.19.8899-8908.2001 11533153 (Pubitemid 32851894)
37. Comparison of the efficacy of Brucella abortus strain RB51 and Brucella melitensis Rev. 1 live vaccines against experimental infection with Brucella melitensis in pregnant ewes. el Idrissi AH, Benkirane A, el Maadoudi M, Bouslikhane M, Berrada J, Zerouali A, Rev Sci Tech 2001 20 3 741 747 11732416 (Pubitemid 33588918)
38. Transfectant influenza A viruses with long deletions in the NS1 protein grow efficiently in vero cells. Egorov A, Brandt S, Sereinig S, Romanova J, Ferko B, Katinger D, Grassauer A, Alexandrova G, Katinger H, Muster T, J Virol 1998 72 8 6437 6441 9658085 (Pubitemid 28323956)
39. Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains. Wang X, Basler CF, Williams BR, Silverman RH, Palese P, Garcia-Sastre A, J Virol 2002 76 12951 12962 10.1128/JVI.76.24.12951-12962.2002 12438621 (Pubitemid 35386979)
40. Preclinical evaluation of a replication-deficient intranasal ΔNS1 H5N1 influenza vaccine. Romanova J, Krenn BM, Wolschek M, Ferko B, Romanovskaja-Romanko E, Morokutti A, Shurygina A-P, Nakowitsch S, Ruthsatz T, Kiefmann B, König U, Bergmann M, Sachet M, Balasingam S, Mann A, Oxford J, Slais M, Kiselev O, Muster T, Egorov A, PLoS One 2009 4 6 5984 doi:10.1371/journal.pone.0005984 10.1371/journal.pone.0005984 19543385
41. A novel type of influenza vaccine: safety and immunogenicity of replication-deficient influenza virus created by deletion of the interferon antagonist NS1. Wacheck V, Egorov A, Groiss F, Pfeiffer A, Fuereder T, Hoeflmayer D, Kundi M, Popow-Kraupp T, Redlberger-Fritz M, Mueller CA, Cinatl J, Michaelis M, Geiler J, Bergmann M, Romanova J, Roethl E, Morokutti A, Wolschek M, Ferko B, Seipelt J, Dick-Gudenus R, Muster T, J Infect Dis 2010 201 3 354 362 doi: 10.1086/649428 10.1086/649428 20039806
42. The role of eye-associated lymphoid tissue in corneal immune protection. Knop E, Knop N, J Anat 2005 206 271 285 10.1111/j.1469-7580.2005.00394.x 15733300 (Pubitemid 40424847)
43. Conjunctiva-associated lymphoid tissue-current knowledge, animal models and experimental prospects. Steven P, Gebert A, Ophthalmic Res 2009 42 2 8 10.1159/000219678 19478534
44. Ocular defense mechanisms with special reference to the demonstration and functional morphology of the conjunctiva-associated lymphoid tissue in Japanese monkeys. Kageyama M, Nakatsuka K, Yamaguchi T, Owen RL, Shimada T, Arch Histol Cytol 2006 69 311 322 10.1679/aohc.69.311 17372387 (Pubitemid 46411223)
45. Ocular tropism of influenza A viruses: identification of H7 subtype-specific host responses in human respiratory and ocular cells. Belser JA, Zeng H, Katz JM, Tumpey TM, J Virol 2011 85 19 10117 10125 10.1128/JVI.05101-11 21775456
46. The protein moiety of outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired Brucellosis. Pasquevich KA, García Samartino C, Coria LM, Estein SM, Zwerdling A, Ibañez AE, Barrionuevo P, Oliveira FS, Carvalho NB, Borkowski J, Oliveira SC, Warzecha H, Giambartolomei GH, Cassataro J, J Immunol 2010 184 9 5200 5212 doi:10.4049/jimmunol.0902209 10.4049/jimmunol.0902209 20351187
47. Novel influenza virus vectors expressing Brucella L7/L12 or Omp16 proteins in cattle induce a strong T-cell immune response, as well as high protectiveness against B. abortus infection. Tabynov K, Kydyrbayev Z, Ryskeldinova S, Yespembetov B, Zinina N, Assanzhanova N, Kozhamkulov Y, Inkarbekov D, Gotskina T, Sansyzbay A, Vaccine 2014 32 2034 2041 10.1016/j.vaccine.2014.02.058 24598723
48. A DNA transfection system for generation of influenza A virus from eight plasmids. Hoffmann E, Neumann G, Kawaoka Y, Hobom G, Webster RG, Proc Natl Acad Sci U S A 2000 97 6108 6113 10.1073/pnas.100133697 10801978 (Pubitemid 30367531)
49. Molecular and genetic analysis of NS gene from high pathogenic strains of the avian influenza (H5N1) virus isolated in Kazakhstan. Chervyakova OV, Strochkov VM, Sultankulova KT, Sandybayev NT, Zaitsev VL, Mamadaliyev SM, Gene 2011 476 15 19 10.1016/j.gene.2011.02.003 21338659
50. WHO manual on animal influenza diagnosis and surveillance. http://www.who.int/csr/resources/publications/influenza/en/whocdscsrncs20025rev. pdf
51. A simple method of estimating fifty percent endpoints. Reed LJ, Muench H, Am J Hyg 1938 27 493 497