Short bowel syndrome: Highlights of patient management, quality of life, and survival

Journal of Parenteral and Enteral Nutrition

Volumn 38, Issue 4, 2014, Pages 427-437

  Kelly, Darlene G ^a   Tappenden, Kelly A ^b   Winkler, Marion F ^c  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

adults; gastroenterology; growth factors; home nutrition support; parenteral nutrition

Indexed keywords

ABSORPTION; ADAPTATION; FLUID RESUSCITATION; HUMAN; ILEUM; MALABSORPTION; PARENTERAL NUTRITION; PATIENT CARE; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; SHORT BOWEL SYNDROME; SURGICAL APPROACH; SURVIVAL; TRANSPLANTATION; DIET THERAPY; DISEASE MANAGEMENT;

GASTROINTESTINAL AGENT;

DISEASE MANAGEMENT; GASTROINTESTINAL AGENTS; HUMANS; NUTRITION THERAPY; PARENTERAL NUTRITION; QUALITY OF LIFE; SHORT BOWEL SYNDROME;

EID: 84899584054     PISSN: 01486071     EISSN: 19412444     Source Type: Journal    
DOI: 10.1177/0148607113512678     Document Type: Review

References (128)

1. Nightingale J, Spiller R Intestinal Failure. Nightingale JMD, ed. London: Greenwich Medical Media ; 2001: 15-36.
2. Messing B, Crenn P, Beau P, Boutron-Ruault MC, Rambaud JC, Matuchansky C. Long-term survival and parenteral nutrition dependence in adult patients with the short bowel syndrome. Gastroenterology. 1999 ; 117: 1043-1050 (Pubitemid 29512662)
3. Misiakos EP, Macheras A, Kapetanakis T, Liakakos T. Short bowel syndrome: current medical and surgical trends. J Clin Gastroenterol. 2007 ; 41: 5-18 (Pubitemid 46045665)
4. Chan S, McCowen KC, Bistrian BR, et al. Incidence, prognosis, and etiology of end-stage liver disease in patients receiving home total parenteral nutrition. Surgery. 1999 ; 126: 28-34 (Pubitemid 29340688)
5. Buchman AL. The medical and surgical management of short bowel syndrome. MedGenMed. 2004 ; 6: 12
6. Santarpia L, Alfonsi L, Tiseo D, et al. Central venous catheter infections and antibiotic therapy during long-term home parenteral nutrition: an 11-year follow-up study. JPEN J Parenter Enteral Nutr. 2010 ; 34: 254-262
7. Gillanders L, Angstmann K, Ball P, et al. A prospective study of catheter-related complications in HPN patients. Clin Nutr. 2012 ; 31: 30-34
8. Green CJ, Mountford V, Hamilton H, Kettlewell MG, Travis SP. A 15-year audit of home parenteral nutrition provision at the John Radcliffe Hospital, Oxford. QJM. 2008 ; 101: 365-369 (Pubitemid 351619244)
9. Lloyd DA, Zabron AA, Gabe SM. Chronic biochemical cholestasis in patients receiving home parenteral nutrition: prevalence and predisposing factors. Aliment Pharmacol Ther. 2008 ; 27: 552-560 (Pubitemid 351316785)
10. Shike M, Harrison JE, Sturtridge WC, et al. Metabolic bone disease in patients receiving long-term total parenteral nutrition. Ann Intern Med. 1980 ; 92: 343-350 (Pubitemid 10154810)
11. Carlsson E, Bosaeus I, Nordgren S. Quality of life and concerns in patients with short bowel syndrome. Clin Nutr. 2003 ; 22: 445-452 (Pubitemid 37259247)
12. Howard L, Heaphey L, Fleming CR, Lininger L, Steiger E. Four years of North American registry home parenteral nutrition outcome data and their implications for patient management. JPEN J Parenter Enteral Nutr. 1991 ; 15: 384-393
13. Juana-Roa J, Wanden-Berghe C, Sanz-Valero J. The reality of home-based parenteral nutrition in Spain. Nutr Hosp. 2011 ; 26: 364-368
14. Van Gossum A, Bakker H, Bozzetti F, et al. Home parenteral nutrition in adults: a European multicentre survey in 1997. ESPEN-Home Artificial Nutrition Working Group. Clin Nutr. 1999 ; 18: 135-140 (Pubitemid 29352027)
15. Mughal M, Irving M. Home parenteral nutrition in the United Kingdom and Ireland. Lancet. 1986 ; 2: 383-387
16. Wanden Berghe C, Gomez Candela C, Chicharro L, et al. Home parenteral nutrition registry in Spain for the year 2010: NADYA-SENPE Group. Nutr Hosp. 2011 ; 26: 1277-1282
17. American Society for Parenteral and Enteral Nutrition. A.S.P.E.N. Launches Sustain™, LLC, a new online patient registry for nutrition support therapy. Available at: http://www.nutritioncare.org/News/A-S-P-E-N- Launches-Sustain,-LLC-A-New-Online-Patient-Registry-for-Nutrition-Support- Therapy/. Accessed June 17, 2013.
18. Messing B, Lemann M, Landais P, et al. Prognosis of patients with nonmalignant chronic intestinal failure receiving long-term home parenteral nutrition. Gastroenterology. 1995 ; 108: 1005-1010
19. Scolapio JS, Fleming CR, Kelly DG, Wick DM, Zinsmeister AR. Survival of home parenteral nutrition-treated patients: 20 years of experience at the Mayo Clinic. Mayo Clin Proc. 1999 ; 74: 217-222 (Pubitemid 29135627)
20. Hess RA, Welch KB, Brown PI, Teitelbaum DH. Survival outcomes of pediatric intestinal failure patients: analysis of factors contributing to improved survival over the past two decades. J Surg Res. 2011 ; 170: 27-31
21. Brenner CJ, Atkinson RL. Short-bowel syndrome: a case report. Nutr Rev. 1989 ; 47: 350-353
22. Genton L, Nardo P, Huber O, Pichard C. Parenteral nutrition independence in a patient left with 25 cm of ileum and jejunum: a case report. Obes Surg. 2010 ; 20: 666-671
23. O'Keefe SJ, Buchman AL, Fishbein TM, Jeejeebhoy KN, Jeppesen PB, Shaffer J. Short bowel syndrome and intestinal failure: consensus definitions and overview. Clin Gastroenterol Hepatol. 2006 ; 4: 6-10 (Pubitemid 43129518)
24. Nordgaard I, Hansen BS, Mortensen PB. Importance of colonic support for energy absorption as small-bowel failure proceeds. Am J Clin Nutr. 1996 ; 64: 222-231 (Pubitemid 26250843)
25. Buchman AL, Scolapio J, Fryer J. AGA technical review on short bowel syndrome and intestinal transplantation. Gastroenterology. 2003 ; 124: 1111-1134 (Pubitemid 36389810)
26. Borgstrom B, Dahlqvist A, Lundh G, Sjovall J. Studies of intestinal digestion and absorption in the human. J Clin Invest. 1957 ; 36: 1521-1536
27. Diamond JM, Karasov WH, Cary C, Enders D, Yung R. Effect of dietary carbohydrate on monosaccharide uptake by mouse small intestine in vitro. J Physiol. 1984 ; 349: 419-440 (Pubitemid 14057481)
28. Hofmann AF, Borgstrom B. Hydrolysis of long-chain monoglycerides in micellar solution by pancreatic lipase. Biochim Biophys Acta. 1963 ; 70: 317-331
29. Hamosh M. Lingual and gastric lipases. Nutrition. 1990 ; 6: 421-428
30. Borgstrom B, Lundh G, Hofmann A. The site of absorption of conjugated bile salts in man. Gastroenterology. 1968 ; 54: 781-783
31. Poley JR, Hofmann AF. Role of fat maldigestion in pathogenesis of steatorrhea in ileal resection. Fat digestion after two sequential test meals with and without cholestyramine. Gastroenterology. 1976 ; 71: 38-44
32. Booth CC, Mollin DL. The site of absorption of vitamin B12 in man. Lancet. 1959 ; 1: 18-21
33. Chutkow JG. Sites of magnesium absorption and excretion in the intestinal tract of the rat. J Lab Clin Med. 1964 ; 63: 71-79
34. Vidal-AlaballJButlerCCCannings-JohnR. Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency. Cochrane Database Syst Rev. 2005CD004655.
35. Buchman A Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 8 th ed.Philadelphia, PA: Saunders; 2006:2257-2276. Feldman M Friedman LS Brandt LJ, ed. Philadelphia, PA: Saunders ; 2257-2276.
36. Hollwarth ME. Short bowel syndrome: pathophysiological and clinical aspects. Pathophysiology. 1999 ; 6: 1-19 (Pubitemid 29244153)
37. Jeppesen PB, Pertkiewicz M, Messing B, et al. Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure. Gastroenterology. 2012 ; 143: 1473-1481
38. Buchman AL, Moukarzel AA, Bhuta S, et al. Parenteral nutrition is associated with intestinal morphologic and functional changes in humans. JPEN J Parenter Enteral Nutr. 1995 ; 19: 453-460
39. Drucker DJ, Erlich P, Asa SL, Brubaker PL. Induction of intestinal epithelial proliferation by glucagon-like peptide 2. Proc Natl Acad Sci U S A. 1996 ; 93: 7911-7916 (Pubitemid 26277138)
40. Tsai CH, Hill M, Asa SL, Brubaker PL, Drucker DJ. Intestinal growth-promoting properties of glucagon-like peptide-2 in mice. Am J Physiol Endocrinol Metab. 1997 ; 273: E77 - E84
41. Tsai CH, Hill M, Drucker DJ. Biological determinants of intestinotrophic properties of GLP-2 in vivo. Am J Physiol. 1997 ; 272: G662 - G668
42. Jeppesen PB, Hartmann B, Thulesen J, et al. Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon. Gastroenterology. 2001 ; 120: 806-815 (Pubitemid 32193176)
43. Quiros-Tejeira RE, Ament ME, Reyen L, et al. Long-term parenteral nutritional support and intestinal adaptation in children with short bowel syndrome: a 25-year experience. J Pediatr. 2004 ; 145: 157-163 (Pubitemid 38993385)
44. Thompson JS, Quigley EM, Adrian TE. Factors affecting outcome following proximal and distal intestinal resection in the dog: an examination of the relative roles of mucosal adaptation, motility, luminal factors, and enteric peptides. Dig Dis Sci. 1999 ; 44: 63-74 (Pubitemid 29053080)
45. Tappenden KA. Mechanisms of enteral nutrient-enhanced intestinal adaptation. Gastroenterology. 2006 ; 130: S93 - S99
46. Feldman EJ, Dowling RH, McNaughton J, Peters TJ. Effects of oral versus intravenous nutrition on intestinal adaptation after small bowel resection in the dog. Gastroenterology. 1976 ; 70: 712-719
47. Ford WD, Boelhouwer RU, King WW, de Vries JE, Ross JS, Malt RA. Total parenteral nutrition inhibits intestinal adaptive hyperplasia in young rats: reversal by feeding. Surgery. 1984 ; 96: 527-534 (Pubitemid 14067501)
48. Johnson LR, Copeland EM, Dudrick SJ, Lichtenberger LM, Castro GA. Structural and hormonal alterations in the gastrointestinal tract of parenterally fed rats. Gastroenterology. 1975 ; 68: 1177-1183
49. Morin CL, Ling V, Van Caillie M. Role of oral intake on intestinal adaptation after small bowel resection in growing rats. Pediatr Res. 1978 ; 12: 268-271 (Pubitemid 8323812)
50. Weser E, Babbitt J, Hoban M, Vandeventer A. Intestinal adaptation. Different growth responses to disaccharides compared with monosaccharides in rat small bowel. Gastroenterology. 1986 ; 91: 1521-1527 (Pubitemid 17176870)
51. Bines JE, Taylor RG, Justice F, et al. Influence of diet complexity on intestinal adaptation following massive small bowel resection in a preclinical model. J Gastroenterol Hepatol. 2002 ; 17: 1170-1179 (Pubitemid 36015612)
52. Messing B, Joly F. Guidelines for management of home parenteral support in adult chronic intestinal failure patients. Gastroenterology. 2006 ; 130: S43 - S51
53. Nordgaard I, Hansen BS, Mortensen PB. Colon as a digestive organ in patients with short bowel. Lancet. 1994 ; 343: 373-376 (Pubitemid 24049553)
54. Kripke SA, Fox AD, Berman JM, Settle RG, Rombeau JL. Stimulation of intestinal mucosal growth with intracolonic infusion of short-chain fatty acids. JPEN J Parenter Enteral Nutr. 1989 ; 13: 109-116 (Pubitemid 19096619)
55. Koruda MJ, Rolandelli RH, Bliss DZ, Hastings J, Rombeau JL, Settle RG. Parenteral nutrition supplemented with short-chain fatty acids: effect on the small-bowel mucosa in normal rats. Am J Clin Nutr. 1990 ; 51: 685-689
56. Tappenden KA, Drozdowski LA, Thomson AB, McBurney MI. Short-chain fatty acid-supplemented total parenteral nutrition alters intestinal structure, glucose transporter 2 (GLUT2) mRNA and protein, and proglucagon mRNA abundance in normal rats. Am J Clin Nutr. 1998 ; 68: 118-125 (Pubitemid 28307663)
57. Tappenden KA, Thomson AB, Wild GE, McBurney MI. Short-chain fatty acid-supplemented total parenteral nutrition enhances functional adaptation to intestinal resection in rats. Gastroenterology. 1997 ; 112: 792-802 (Pubitemid 27113805)
58. Sakata T. Stimulatory effect of short-chain fatty acids on epithelial cell proliferation in the rat intestine: a possible explanation for trophic effects of fermentable fibre, gut microbes and luminal trophic factors. Br J Nutr. 1987 ; 58: 95-103 (Pubitemid 17105567)
59. Tappenden KA, McBurney MI. Systemic short-chain fatty acids rapidly alter gastrointestinal structure, function, and expression of early response genes. Dig Dis Sci. 1998 ; 43: 1526-1536 (Pubitemid 28357274)
60. Bartholome AL, Albin DM, Baker DH, Holst JJ, Tappenden KA. Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. JPEN J Parenter Enteral Nutr. 2004 ; 28: 210-223 (Pubitemid 38812674)
61. Atia A, Girard-Pipau F, Hebuterne X, et al. Macronutrient absorption characteristics in humans with short bowel syndrome and jejunocolonic anastomosis: starch is the most important carbohydrate substrate, although pectin supplementation may modestly enhance short chain fatty acid production and fluid absorption. JPEN J Parenter Enteral Nutr. 2011 ; 35: 229-240
62. Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995 ; 125: 1401-1412
63. Doldi SB. Intestinal adaptation following jejuno-ileal bypass. Clin Nutr. 1991 ; 10: 138-145
64. Hines OJ, Bilchik AJ, McFadden DW, et al. Up-regulation of Na+,K+ adenosine triphosphatase after massive intestinal resection. Surgery. 1994 ; 116: 401-407
65. Hines OJ, Bilchik AJ, Zinner MJ, et al. Adaptation of the Na+/glucose cotransporter following intestinal resection. J Surg Res. 1994 ; 57: 22-27 (Pubitemid 24243232)
66. Weale AR, Edwards AG, Bailey M, Lear PA. Intestinal adaptation after massive intestinal resection. Postgrad Med J. 2005 ; 81: 178-184 (Pubitemid 40387967)
67. Cataldi-Betcher EL, Seltzer MH, Slocum BA, Jones KW. Complications occurring during enteral nutrition support: a prospective study. JPEN J Parenter Enteral Nutr. 1983 ; 7: 546-552 (Pubitemid 14201679)
68. Crenn P, Coudray-Lucas C, Thuillier F, Cynober L, Messing B. Postabsorptive plasma citrulline concentration is a marker of absorptive enterocyte mass and intestinal failure in humans. Gastroenterology. 2000 ; 119: 1496-1505 (Pubitemid 32198675)
69. Pironi L, Joly F, Forbes A, et al. Long-term follow-up of patients on home parenteral nutrition in Europe: implications for intestinal transplantation. Gut. 2011 ; 60: 17-25
70. Barnadas G. Navigating home care: parenteral nutrition - part two. Pract Gastroenterol. 2003 ; 27: 13-30 (Pubitemid 37532249)
71. Kelly DG. The clinician's responsibility for the consumer's financial well-being. Nutr Clin Pract. 2006 ; 21: 539-541 (Pubitemid 44863572)
72. U.S. Department of Health and Human Services HCFA. 65-10 Enteral and parenteral nutritional therapy covered as prosthetic device; 2000.
73. Scolapio JS, Fleming CR. Short bowel syndrome. Gastroenterol Clin North Am. 1998 ; 27: 467-479 (Pubitemid 28325393)
74. Parrish CR. The clinician's guide to short bowel syndrome. Pract Gastroenterol. 2005 ; 29: 67-106 (Pubitemid 41451924)
75. Spiller RC, Jones BJ, Silk DB. Jejunal water and electrolyte absorption from two proprietary enteral feeds in man: importance of sodium content. Gut. 1987 ; 28: 681-687 (Pubitemid 17082214)
76. Sundaram A, Koutkia P, Apovian CM. Nutritional management of short bowel syndrome in adults. J Clin Gastroenterol. 2002 ; 34: 207-220 (Pubitemid 34177371)
77. Compher C, Winkler M, Boullata JI Clinical Nutrition for Surgical Patients. Marian M Russell MK Shikora SA, ed. Sudbury, MA: Jones and Bartlett ; 2008: 283-305.
78. Kelly DG, Nadeau J. Oral rehydration solution: a "low-tech" oft neglected therapy. Pract Gastroenterol. 2004 ; 28: 51-62 (Pubitemid 39586999)
79. Kalaitzakis E, Carlsson E, Josefsson A, Bosaeus I. Quality of life in short-bowel syndrome: impact of fatigue and gastrointestinal symptoms. Scand J Gastroenterol. 2008 ; 43: 1057-1065
80. Baxter JP, Fayers PM, McKinlay AW. The clinical and psychometric validation of a questionnaire to assess the quality of life of adult patients treated with long-term parenteral nutrition. JPEN J Parenter Enteral Nutr. 2010 ; 34: 131-142
81. Jeppesen PB, Pertkiewicz M, Forbes A, et al. Quality of life in patients with short bowel syndrome treated with the new glucagon-like peptide-2 analogue teduglutide - analyses from a randomised, placebo-controlled study. Clin Nutr. 2013 ; 32: 713-721
82. Winkler MF, Hagan E, Wetle T, Smith C, Maillet JO, Touger-Decker R. An exploration of quality of life and the experience of living with home parenteral nutrition. JPEN J Parenter Enteral Nutr. 2010 ; 34: 395-407
83. Winkler MF, Ross VM, Piamjariyakul U, Gajewski B, Smith CE. Technology dependence in home care: impact on patients and their family caregivers. Nutr Clin Pract. 2006 ; 21: 544-556 (Pubitemid 44863574)
84. Persoon A, Huisman-de Waal G, Naber TA, et al. Impact of long-term HPN on daily life in adults. Clin Nutr. 2005 ; 24: 304-313 (Pubitemid 40392817)
85. Lehoux P, Saint-Arnaud J, Richard L. The use of technology at home: what patient manuals say and sell vs. what patients face and fear. Sociol Health Illn. 2004 ; 26: 617-644 (Pubitemid 39091833)
86. Hall RC, Stickney SK, Gardner ER, Popkin MK. Psychiatric reactions to long-term intravenous hyperalimentation. Psychosomatics. 1981 ; 22: 428-443 (Pubitemid 11079695)
87. Stern J. Home parenteral nutrition and the psyche: psychological challenges for patient and family. Proc Nutr Soc. 2006 ; 65: 222-226 (Pubitemid 46323837)
88. MacRitchie KJ. Parenteral nutrition outside hospital: psychosocial styles of adaptation. Can J Psychiatry. 1980 ; 25: 308-313
89. Silver HJ. The lived experience of home total parenteral nutrition: an online qualitative inquiry with adults, children, and mothers. Nutr Clin Pract. 2004 ; 19: 297-304 (Pubitemid 38747827)
90. Huisman-de Waal G, Schoonhoven L, Jansen J, Wanten G, van Achterberg T. The impact of home parenteral nutrition on daily life-a review. Clin Nutr. 2007 ; 26: 275-288 (Pubitemid 46760472)
91. Malone M. Longitudinal assessment of outcome, health status, and changes in lifestyle associated with long-term home parenteral and enteral nutrition. JPEN J Parenter Enteral Nutr. 2002 ; 26: 164-168 (Pubitemid 34429480)
92. Fortune DG, Varden J, Parker S, Harper L, Richards HL, Shaffer JL. Illness beliefs of patients on home parenteral nutrition (HPN) and their relation to emotional distress. Clin Nutr. 2005 ; 24: 896-903 (Pubitemid 41782445)
93. Robb RA, Brakebill JI, Ivey MF, Christensen DB, Young JH, Scribner BH. Subjective assessment of patient outcomes of home parenteral nutrition. Am J Hosp Pharm. 1983 ; 40: 1646-1650
94. Herfindal ET, Bernstein LR, Kudzia K, Wong A. Survey of home nutritional support patients. JPEN J Parenter Enteral Nutr. 1989 ; 13: 255-261 (Pubitemid 19141314)
95. Huisman-de Waal G, Naber T, Schoonhoven L, Persoon A, Sauerwein H, van Achterberg T. Problems experienced by patients receiving parenteral nutrition at home: results of an open interview study. JPEN J Parenter Enteral Nutr. 2006 ; 30: 215-221
96. Lehoux P. Patients' perspectives on high-tech home care: a qualitative inquiry into the user-friendliness of four technologies. BMC Health Serv Res. 2004 ; 4: 28
97. Scolapio JS, Savoy AD, Kaplan J, Burger CD, Lin SC. Sleep patterns of cyclic parenteral nutrition, a pilot study: are there sleepless nights?. JPEN J Parenter Enteral Nutr. 2002 ; 26: 214-217 (Pubitemid 34429489)
98. Winkler MF, Wetle T, Smith C, Hagan E, O'Sullivan Maillet J, Touger-Decker R. The meaning of food and eating among home parenteral nutrition-dependent adults with intestinal failure: a qualitative inquiry. J Am Diet Assoc. 2010 ; 110: 1676-1683
99. Robinson CA. Managing life with a chronic condition: the story of normalization. Qual Health Res. 1993 ; 3: 6-28
100. Smith CE, Curtas S, Werkowitch M, Kleinbeck SV, Howard L. Home parenteral nutrition: does affiliation with a national support and educational organization improve patient outcomes?. JPEN J Parenter Enteral Nutr. 2002 ; 26: 159-163 (Pubitemid 34429479)
101. Buchman AL. Short-bowel syndrome. Clin Gastroenterol Hepatol. 2005 ; 3: 1066-1070 (Pubitemid 41565370)
102. Matarese LE. Nutrition and fluid optimization for patients with short bowel syndrome. JPEN J Parenter Enteral Nutr. 2013 ; 37: 161-170
103. Goulet O, Ruemmele F. Causes and management of intestinal failure in children. Gastroenterology. 2006 ; 130: S16 - S28
104. Placidi E, Marciani L, Hoad CL, et al. The effects of loperamide, or loperamide plus simethicone, on the distribution of gut water as assessed by MRI in a mannitol model of secretory diarrhoea. Aliment Pharmacol Ther. 2012 ; 36: 64-73
105. Van Wyk M, Sommers DK, Steyn AG. Evaluation of gastrointestinal motility using the hydrogen breath test. Br J Clin Pharmacol. 1985 ; 20: 479-481 (Pubitemid 16230369)
106. Nguyen BT, Blatchford GJ, Thompson JS, Bragg LE. Should intestinal continuity be restored after massive intestinal resection?. Am J Surg. 1989 ; 158: 577-579
107. Thompson JS, Langnas AN. Surgical approaches to improving intestinal function in the short-bowel syndrome. Arch Surg. 1999 ; 134: 706-709
108. Bianchi A. Intestinal loop lengthening - a technique for increasing small intestinal length. J Pediatr Surg. 1980 ; 15: 145-151 (Pubitemid 10110498)
109. Thompson JS, Rochling FA, Weseman RA, Mercer DF. Current management of short bowel syndrome. Curr Probl Surg. 2012 ; 49: 52-115
110. Gibson LD, Carter R, Hinshaw DB. Segmental reversal of small intestine after massive bowel resection. Successful case with follow-up examination. JAMA. 1962 ; 182: 952-954
111. Abu-Elmagd KM, Costa G, Bond GJ, et al. Five hundred intestinal and multivisceral transplantations at a single center: major advances with new challenges. Ann Surg. 2009 ; 250: 567-581
112. Salvino R, Ghanta R, Seidner DL, Mascha E, Xu Y, Steiger E. Liver failure is uncommon in adults receiving long-term parenteral nutrition. JPEN J Parenter Enteral Nutr. 2006 ; 30: 202-208
113. Byrne TA, Morrissey TB, Nattakom TV, Ziegler TR, Wilmore DW. Growth hormone, glutamine, and a modified diet enhance nutrient absorption in patients with severe short bowel syndrome. JPEN J Parenter Enteral Nutr. 1995 ; 19: 296-302
114. Wales PW, Nasr A, de Silva N, Yamada J. Human growth hormone and glutamine for patients with short bowel syndrome. Cochrane Database Syst Rev. :
115. Drucker DJ. Gut adaptation and the glucagon-like peptides. Gut. 2002 ; 50: 428-435 (Pubitemid 34161064)
116. Dahly EM, Gillingham MB, Guo Z, et al. Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid-small bowel resection. Am J Physiol Gastrointest Liver Physiol. 2003 ; 284: G670 - G682
117. Jeppesen PB, Sanguinetti EL, Buchman A, et al. Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients. Gut. 2005 ; 54: 1224-1231 (Pubitemid 41192479)
118. Marier JF, Beliveau M, Mouksassi MS, et al. Pharmacokinetics, safety, and tolerability of teduglutide, a glucagon-like peptide-2 (GLP-2) analog, following multiple ascending subcutaneous administrations in healthy subjects. J Clin Pharmacol. 2008 ; 48: 1289-1299
119. Jeppesen PB, Gilroy R, Pertkiewicz M, Allard JP, Messing B, O'Keefe SJ. Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome. Gut. 2011 ; 60: 902-914
120. Winker MF, Fujioka K, Youssef N, et al. Teduglutide enhances nutrient absorption in adult subjects with short bowel syndrome and maintains nutritional balance despite significant reductions in parenteral support. JPEN J Parenter Enteral Nutr. 2012 ; 36: 127-128
121. Tappenden KA, Edelman J, Joelsson B. Teduglutide enhances structural adaptation of the small intestinal mucosa in patients with short bowel syndrome. J Clin Gastroenterol. 2013 ; 47: 602-607
122. Jeppesen PB, Pertkiewicz M, Messing B, et al. Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure. Gastroenterology. 2012 ; 143: 1473-1481
123. O'Keefe SJ, Jeppesen PB, Gilroy R, Pertkiewicz M, Allard JP, Messing B. Safety and efficacy of teduglutide after 52 weeks of treatment in patients with short bowel syndrome-intestinal failure. Clin Gastroenterol Hepatol. 2013 ; 11: 815-823
124. Schwartz LK, Seidner DL, Jeppesen PB, Pertkiewicz M, Youssef N, Heinze H. Teduglutide (TED) for the treatment of short bowel syndrome-intestinal failure (SBS-IF) subjects yields further reductions in parenteral support (PS): an interim assessment of a 2-year, open-label, phase 3 trial (STEPS2). Am J Gastroenterol. 2011 ; 106: S99
125. Seidner DL, Schwartz LK, Winkler MF, Jeejeebhoy K, Boullata JI, Tappenden KA. Increased intestinal absorption in the era of teduglutide and its impact on management strategies in patients with short bowel syndrome-associated intestinal failure. JPEN J Parenter Enteral Nutr. 2013 ; 37: 201-211
126. Jeppesen PB. The non-surgical treatment of adult patients with short bowel syndrome. Expert Opin Orphan Drugs. 2013 ; 1: 527-538
127. Gennari FJ, Weise WJ. Acid-base disturbances in gastrointestinal disease. Clin J Am Soc Nephrol. 2008 ; 3: 1861-1868
128. Richards DM, Scott NA, Shaffer JL, Irving M. Opiate and sedative dependence predicts a poor outcome for patients receiving home parenteral nutrition. JPEN J Parenter Enteral Nutr. 1997 ; 21: 336-338 (Pubitemid 27505896)