-
1
-
-
0035856952
-
Beta-cell death during progression to diabetes
-
Mathis D, Vence L, Benoist C (2001) Beta-cell death during progression to diabetes. Nature 414:792-8.
-
(2001)
Nature
, vol.414
, pp. 792-798
-
-
Mathis, D.1
Vence, L.2
Benoist, C.3
-
2
-
-
33749070784
-
International trial of the Edmonton protocol for islet transplantation
-
Shapiro AM, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, et al. (2006) Robertson RP, Secchi A, Brendel MD, Berney T, Brennan DC, et al. International trial of the Edmonton protocol for islet transplantation. N Engl J v. 355:1318-1330.
-
(2006)
N Engl J V
, vol.355
, pp. 1318-1330
-
-
Shapiro, A.M.1
Ricordi, C.2
Hering, B.J.3
Auchincloss, H.4
Lindblad, R.5
Robertson, R.P.6
Secchi, A.7
Brendel, M.D.8
Berney, T.9
Brennan, D.C.10
-
3
-
-
77953193333
-
Islet transplantation a decade later and strategies for filling a half-full glass
-
Robertson RP (2010) Islet transplantation a decade later and strategies for filling a half-full glass. Diabetes.59:1285-91.
-
(2010)
Diabetes
, vol.59
, pp. 1285-1291
-
-
Robertson, R.P.1
-
4
-
-
77956263517
-
Immune intervention in children with type 1 diabetes
-
Ludvigsson J (2010) Immune intervention in children with type 1 diabetes. Curr Diab Rep.10:370-9.
-
(2010)
Curr Diab Rep
, vol.10
, pp. 370-379
-
-
Ludvigsson, J.1
-
5
-
-
0026000815
-
Use of a highly purified alpha 1-antitrypsin standard to establish ranges for the common normal and deficient alpha 1-antitrypsin phenotypes
-
Brantly ML, Wittes JT, Vogelmeier CF, Hubbard RC, Fells GA, et al. (1991) Use of a highly purified alpha 1-antitrypsin standard to establish ranges for the common normal and deficient alpha 1-antitrypsin phenotypes. Chest.100:703-8.
-
(1991)
Chest
, vol.100
, pp. 703-708
-
-
Brantly, M.L.1
Wittes, J.T.2
Vogelmeier, C.F.3
Hubbard, R.C.4
Fells, G.A.5
-
6
-
-
0034883830
-
Alpha-1-antitrypsin and a broad spectrum metalloprotease inhibitor, RS113456, have similar acute anti-inflammatory effects
-
Churg A, Dai J, Zay K, Karsan A, Hendricks R, et al. (2001) Alpha-1-antitrypsin and a broad spectrum metalloprotease inhibitor, RS113456, have similar acute anti-inflammatory effects. Lab Invest. 81:1119-31. (Pubitemid 32772072)
-
(2001)
Laboratory Investigation
, vol.81
, Issue.8
, pp. 1119-1131
-
-
Churg, A.1
Dai, J.2
Zay, K.3
Karsan, A.4
Hendricks, R.5
Yee, C.6
Martin, R.7
MacKenzie, R.8
Xie, C.9
Zhang, L.10
Shapiro, S.11
Wright, J.L.12
-
7
-
-
0347527156
-
1-antitrypsin on acute lung injury in rabbits induced by endotoxin
-
Jie Z, Cai Y, Yang W, Jin M, Zhu W, et al. (2003) Protective effects of alpha 1-antitrypsin on acute lung injury in rabbits induced by endotoxin. Chin Med J (Engl). 116:1678-82. (Pubitemid 38008236)
-
(2003)
Chinese Medical Journal
, vol.116
, Issue.11
, pp. 1678-1682
-
-
Jie, Z.1
Cai, Y.2
Yang, W.3
Jin, M.4
Zhu, W.5
Zhu, C.6
-
8
-
-
24644461309
-
Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice
-
DOI 10.1073/pnas.0505579102
-
Lewis EC, Shapiro L, Bowers OJ, Dinarello CA (2005) Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice. Proc Natl Acad Sci USA 102:12153-12158. (Pubitemid 41291144)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.34
, pp. 12153-12158
-
-
Lewis, E.C.1
Shapiro, L.2
Bowers, O.J.3
Dinarello, C.A.4
-
9
-
-
33744945064
-
1-antitrypsin in the prevention of pulmonary emphysema
-
DOI 10.1164/rccm.200512-1842OC
-
Petrache I, Fijalkowska I, Zhen L, Medler TR, Brown E, et al. (2006) A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema.Am J Respir Crit Care Med.173:1222-8. (Pubitemid 43848392)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.173
, Issue.11
, pp. 1222-1228
-
-
Petrache, I.1
Fijalkowska, I.2
Zhen, L.3
Medler, T.R.4
Brown, E.5
Cruz, P.6
Choe, K.-H.7
Taraseviciene-Stewart, L.8
Scerbavicius, R.9
Shapiro, L.10
Zhang, B.11
Song, S.12
Hicklin, D.13
Voelkel, N.F.14
Flotte, T.15
Tuder, R.M.16
-
10
-
-
34248178516
-
Alpha1-antitrypsin protects beta-cells from apoptosis
-
Zhang B, Lu Y, Campbell-Thompson M, Spencer T, Wasserfall C, et al. (2007) Alpha1-antitrypsin protects beta-cells from apoptosis. Diabetes. 56:1316-23.
-
(2007)
Diabetes
, vol.56
, pp. 1316-1323
-
-
Zhang, B.1
Lu, Y.2
Campbell-Thompson, M.3
Spencer, T.4
Wasserfall, C.5
-
11
-
-
0036882115
-
Alpha1-antitrypsin: Not just an antiprotease: Extending the half-life of a natural anti-inflammatory molecule by conjugation with polyethylene glycol
-
Brantly M (2002) Alpha1-antitrypsin: Not just an antiprotease: extending the half-life of a natural anti-inflammatory molecule by conjugation with polyethylene glycol. Am J Respir Cell Mol Biol 27:652-654.
-
(2002)
Am J Respir Cell Mol Biol
, vol.27
, pp. 652-654
-
-
Brantly, M.1
-
12
-
-
33745662827
-
Alpha1- antitrypsin gene therapy modulates cellular immunity and efficiently prevents type 1 diabetes in nonobese diabetic mice
-
1
-
Lu Y1, Tang M, Wasserfall C, Kou Z, Campbell-Thompson M, et al. (2006) Alpha1- antitrypsin gene therapy modulates cellular immunity and efficiently prevents type 1 diabetes in nonobese diabetic mice. Hum Gene Ther. 17:625-34.
-
(2006)
Hum Gene Ther
, vol.17
, pp. 625-634
-
-
Lu, Y.1
Tang, M.2
Wasserfall, C.3
Kou, Z.4
Campbell-Thompson, M.5
-
13
-
-
55849101706
-
alpha1- Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice
-
1
-
Lewis EC1, Mizrahi M, Toledano M, Defelice N, Wright JL, et al. (2008) alpha1- Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice. Proc Natl Acad Sci U S A. 105:16236-41.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16236-16241
-
-
Lewis, E.C.1
Mizrahi, M.2
Toledano, M.3
Defelice, N.4
Wright, J.L.5
-
14
-
-
0025878776
-
NIT-1, a pancreatic beta-cell line established from a transgenic NOD/Lt mouse
-
Hamaguchi K, Gaskins H, Leiter E (1991) NIT-1, a pancreatic beta-cell line established from a transgenic NOD/Lt mouse. Diabetes 40:842-849.
-
(1991)
Diabetes
, vol.40
, pp. 842-849
-
-
Hamaguchi, K.1
Gaskins, H.2
Leiter, E.3
-
15
-
-
84862804393
-
Reversible immortalization of Nestin-positive precursor cells from pancreas and differentiation into insulin-secreting cells
-
Wei P, Li L, Qi H, Zhou HX, Deng CY, et al. (2012) Reversible immortalization of Nestin-positive precursor cells from pancreas and differentiation into insulin-secreting cells. Biochem Biophys Res Commun.418:330-5.
-
(2012)
Biochem Biophys Res Commun
, vol.418
, pp. 330-335
-
-
Wei, P.1
Li, L.2
Qi, H.3
Zhou, H.X.4
Deng, C.Y.5
-
16
-
-
63349102628
-
Control of inflammation with alpha1-antitrypsin: A potential treatment for islet transplantation and new-onset type 1 diabetes
-
Weir GC, Koulamnda M (2009) Control of inflammation with alpha1-antitrypsin: a potential treatment for islet transplantation and new-onset type 1 diabetes. Curr Diab Rep. 9:100-2.
-
(2009)
Curr Diab Rep
, vol.9
, pp. 100-102
-
-
Weir, G.C.1
Koulamnda, M.2
-
17
-
-
84874522014
-
Alpha-1-antitrypsin for the improvement of autoimmunity and allograft rejection in beta cell transplantation
-
Ye J, Liao YT, Jian YQ, Zhang XD, Wei P, et al. (2013) Alpha-1-antitrypsin for the improvement of autoimmunity and allograft rejection in beta cell transplantation. Immunology Letters.150:61-8.
-
(2013)
Immunology Letters
, vol.150
, pp. 61-68
-
-
Ye, J.1
Liao, Y.T.2
Jian, Y.Q.3
Zhang, X.D.4
Wei, P.5
-
18
-
-
8744254743
-
Tissue factor and CCL2/monocyte chemoattractant protein-1 released by human islets affect islet engraftment in type 1 diabetic recipients
-
DOI 10.1210/jc.2004-0659
-
Bertuzzi F, Marzorati S, Maffi P, Piemonti L, Melzi R, et al. (2004) Tissue factor and CCL2/monocyte chemoattractant protein-1 released by human islets affect islet engraftment in type 1 diabetic recipients. J Clin Endocrinol Metab. 89:5724-8. (Pubitemid 39518465)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.11
, pp. 5724-5728
-
-
Bertuzzi, F.1
Marzorati, S.2
Maffi, P.3
Piemonti, L.4
Melzi, R.5
De Taddeo, F.6
Valtolina, V.7
D'angelo, A.8
Di, C.V.9
Bonifacio, E.10
Secchi, A.11
-
19
-
-
9144253897
-
Differential Role of CCR2 in Islet and Heart Allograft Rejection: Tissue Specificity of Chemokine/Chemokine Receptor Function In Vivo
-
Abdi R, Means TK, Ito T, Smith RN, Najafian N, et al. (2004) Differential role of CCR2 in islet and heart allograft rejection: tissue specificity of chemokine/chemokine receptor function in vivo. J Immunol. 172:767-75. (Pubitemid 38113732)
-
(2004)
Journal of Immunology
, vol.172
, Issue.2
, pp. 767-775
-
-
Abdi, R.1
Means, T.K.2
Ito, T.3
Smith, R.N.4
Najafian, N.5
Jurewicz, M.6
Tchipachvili, V.7
Charo, I.8
Auchincloss Jr., H.9
Sayegh, M.H.10
Luster, A.D.11
-
20
-
-
53749100698
-
Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta - Cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation
-
Böni-Schnetzler M, Thorne J, Parnaud G, Marselli L, Ehses JA, et al. (2008) Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta - cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation. J Clin Endocrinol Metab 93:4065-74.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4065-4074
-
-
Böni-Schnetzler, M.1
Thorne, J.2
Parnaud, G.3
Marselli, L.4
Ehses, J.A.5
-
21
-
-
79956144622
-
C reactive protein and alpha1-antitrypsin: Relationship between levels and gene variants
-
Ottaviani S, Gorrini M, Scabini R, Kadija Z, Paracchini E, et al. (2011) C reactive protein and alpha1-antitrypsin: relationship between levels and gene variants.Transl Res. 157:332-8.
-
(2011)
Transl Res
, vol.157
, pp. 332-338
-
-
Ottaviani, S.1
Gorrini, M.2
Scabini, R.3
Kadija, Z.4
Paracchini, E.5
-
22
-
-
70349275250
-
Virus-encoded homologs of cellular interleukin-10 and their control of host immune function
-
Slobedman B, Barry PA, Spencer JV, Avdic S, Abendroth A (2009) Virus-encoded homologs of cellular interleukin-10 and their control of host immune function.J Virol. 83:9618-29.
-
(2009)
J Virol
, vol.83
, pp. 9618-9629
-
-
Slobedman, B.1
Barry, P.A.2
Spencer, J.V.3
Avdic, S.4
Abendroth, A.5
-
23
-
-
84862860546
-
á-1 antitrypsin promotes semimature, IL-10-producing and readily migrating tolerogenic dendritic cells
-
Ozeri E, Mizrahi M, Shahaf G, Lewis EC (2012) á-1 antitrypsin promotes semimature, IL-10-producing and readily migrating tolerogenic dendritic cells. J Immunol. 189:146-53.
-
(2012)
J Immunol
, vol.189
, pp. 146-153
-
-
Ozeri, E.1
Mizrahi, M.2
Shahaf, G.3
Lewis, E.C.4
-
24
-
-
84862908801
-
Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation
-
Tawara I, Sun Y, Lewis EC, Toubai T, Evers R, et al. (2012) Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation. Proc Natl Acad Sci U S A. 109:564-9.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 564-569
-
-
Tawara, I.1
Sun, Y.2
Lewis, E.C.3
Toubai, T.4
Evers, R.5
-
25
-
-
84866525419
-
Alpha 1-antitrypsin reduces inflammation and enhances mouse pancreatic islet transplant survival
-
Koulmanda M, Bhasin M, Fan Z, Hanidziar D, Goel N, et al. (2012) Alpha 1-antitrypsin reduces inflammation and enhances mouse pancreatic islet transplant survival. Proc Natl Acad Sci U S A 109:15443-8.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 15443-15448
-
-
Koulmanda, M.1
Bhasin, M.2
Fan, Z.3
Hanidziar, D.4
Goel, N.5
-
26
-
-
34248178516
-
Alpha1-antitrypsin protects beta-cells from apoptosis
-
Zhang B, Lu Y, Campbell-Thompson M, Spencer T, Wasserfall C, et al. (2007) Alpha1-antitrypsin protects beta-cells from apoptosis. Diabetes. 56: 1316-23.
-
(2007)
Diabetes
, vol.56
, pp. 1316-1323
-
-
Zhang, B.1
Lu, Y.2
Campbell-Thompson, M.3
Spencer, T.4
Wasserfall, C.5
-
27
-
-
79953250407
-
A 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic β-cells
-
Kalis M, Kumar R, Janciauskiene S, Salehi A, Cilio CM (2010)a 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic β-cells. Islets. 2:185-9.
-
(2010)
Islets
, vol.2
, pp. 185-189
-
-
Kalis, M.1
Kumar, R.2
Janciauskiene, S.3
Salehi, A.4
Cilio, C.M.5
-
28
-
-
84858776868
-
α-1-antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents islet allograft rejection
-
Shahaf G, Moser H, Ozeri E, Mizrahi M, Abecassis A, et al. (2011) α-1-antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents islet allograft rejection. Mol Med. 17:1000-11.
-
(2011)
Mol Med
, vol.17
, pp. 1000-1011
-
-
Shahaf, G.1
Moser, H.2
Ozeri, E.3
Mizrahi, M.4
Abecassis, A.5
-
29
-
-
60549093646
-
Increased CD4+Foxp3+ T cells in BAFF-transgenic mice suppress T cell effector responses
-
Walters S, Webster KE, Sutherland A, Gardam S, Groom J, et al. (2009) Increased CD4+Foxp3+ T cells in BAFF-transgenic mice suppress T cell effector responses. J Immunol. 182:793-801.
-
(2009)
J Immunol
, vol.182
, pp. 793-801
-
-
Walters, S.1
Webster, K.E.2
Sutherland, A.3
Gardam, S.4
Groom, J.5
-
30
-
-
65549125443
-
Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood
-
Pott GB, Chan ED, Dinarello CA, Shapiro L (2009) Alpha-1-antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood. J Leukoc Biol. 85:886-95.
-
(2009)
J Leukoc Biol
, vol.85
, pp. 886-895
-
-
Pott, G.B.1
Chan, E.D.2
Dinarello, C.A.3
Shapiro, L.4
|