Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer

Oxidative Medicine and Cellular Longevity

Volumn 2014, Issue , 2014, Pages

  Shinmura, Kazuya ^a   Goto, Masanori ^a,b   Tao, Hong ^a   Kato, Hisami ^a   Suzuki, Rie ^a   Nakamura, Satoki ^a   Matsuda, Tomonari ^c   Yin, Guang ^d   Morita, Makiko ^d   Kono, Suminori ^d   Sugimura, Haruhiko ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; GENES;

8-HYDROXYGUANINE; COLORECTAL CANCER; COLORECTAL CANCERS (CRC); DNA CLEAVAGE; DNA REPAIR; LIMITED INFORMATION; MUTATION ASSAYS; PATHOGENIC MUTATION;

REPAIR;

8-HYDROXYGUANINE; DNA GLYCOSYLASE MUTY; DNA GLYCOSYLTRANSFERASE; GUANINE; OXOGUANINE GLYCOSYLASE 1, HUMAN;

ADULT; ALLELE; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; ANIMAL; ASIAN CONTINENTAL ANCESTRY GROUP; CHEMISTRY; COLORECTAL TUMOR; DNA REPAIR; FEMALE; GENE FREQUENCY; GENETICS; GENOTYPE; HETEROZYGOTE; HUMAN; MALE; METABOLISM; MOLECULAR GENETICS; MUTATION; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

ADULT; ALLELES; AMINO ACID SEQUENCE; ANIMALS; ASIAN CONTINENTAL ANCESTRY GROUP; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DNA GLYCOSYLASES; DNA REPAIR; FEMALE; GENE FREQUENCY; GENOTYPE; GUANINE; HETEROZYGOTE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION;

EID: 84899516815     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2014/617351     Document Type: Article

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