-
1
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
Aguirre-Ghiso JA. Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer 2007;7:834-46.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
2
-
-
33748923798
-
Opposing roles of mitogenic and stress signaling pathways in the induction of cancer dormancy
-
Ranganathan AC, Adam AP, Aguirre-Ghiso JA. Opposing roles of mitogenic and stress signaling pathways in the induction of cancer dormancy. Cell Cycle 2006;5:1799-807.
-
(2006)
Cell Cycle
, vol.5
, pp. 1799-1807
-
-
Ranganathan, A.C.1
Adam, A.P.2
Aguirre-Ghiso, J.A.3
-
3
-
-
84863011934
-
Cancer dormancy: A model of early dissemination and late cancer recurrence
-
Paez D, Labonte MJ, Bohanes P, Zhang W, Benhanim L, Ning Y, et al. Cancer dormancy: a model of early dissemination and late cancer recurrence. Clin Cancer Res 2012;18:645-53.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 645-653
-
-
Paez, D.1
Labonte, M.J.2
Bohanes, P.3
Zhang, W.4
Benhanim, L.5
Ning, Y.6
-
4
-
-
0032867023
-
Relapse after complete response to anthracycline-based combination chemotherapy in metastatic breast cancer
-
Pusztai L, Asmar L, Smith TL, Hortobagyi GN. Relapse after complete response to anthracycline-based combination chemotherapy in metastatic breast cancer. Breast Cancer Res Treat 1999;55:1-8.
-
(1999)
Breast Cancer Res Treat
, vol.55
, pp. 1-8
-
-
Pusztai, L.1
Asmar, L.2
Smith, T.L.3
Hortobagyi, G.N.4
-
5
-
-
33846815517
-
Significance, detection and markers of disseminated breast cancer cells
-
Lacroix M. Significance, detection and markers of disseminated breast cancer cells. Endocr Relat Cancer 2006;13:1033-67.
-
(2006)
Endocr Relat Cancer
, vol.13
, pp. 1033-1067
-
-
Lacroix, M.1
-
6
-
-
0034865262
-
Tumour dormancy: Findings and hypotheses from clinical research on breast cancer
-
Demicheli R. Tumour dormancy: findings and hypotheses from clinical research on breast cancer. Semin Cancer Biol 2001;11:297-306.
-
(2001)
Semin Cancer Biol
, vol.11
, pp. 297-306
-
-
Demicheli, R.1
-
7
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat Rev Cancer 2005;5:275-84.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
8
-
-
0347504928
-
Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases
-
Naumov GN, Townson JL, MacDonald IC, Wilson SM, Bramwell VH, Groom AC, et al. Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases. Breast Cancer Res Treat 2003;82:199-206.
-
(2003)
Breast Cancer Res Treat
, vol.82
, pp. 199-206
-
-
Naumov, G.N.1
Townson, J.L.2
Macdonald, I.C.3
Wilson, S.M.4
Bramwell, V.H.5
Groom, A.C.6
-
9
-
-
84890259230
-
A novel model of dormancy for bone metastatic breast cancer cells
-
Marlow R, Honeth G,Lombardi S, Cariati M, Hessey SM, Pipili A, et al.A novel model of dormancy for bone metastatic breast cancer cells. Cancer Res 2013;73:6886-99.
-
(2013)
Cancer Res
, vol.73
, pp. 6886-6899
-
-
Marlow, R.1
Honeth, G.2
Lombardi, S.3
Cariati, M.4
Hessey, S.M.5
Pipili, A.6
-
10
-
-
84880332704
-
The perivascular niche regulates breast tumour dormancy
-
Ghajar CM, Peinado H, Mori H, Matei IR, Evason KJ, Brazier H, et al. The perivascular niche regulates breast tumour dormancy. Nat Cell Biol 2013;15:807-17.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 807-817
-
-
Ghajar, C.M.1
Peinado, H.2
Mori, H.3
Matei, I.R.4
Evason, K.J.5
Brazier, H.6
-
11
-
-
77955021301
-
Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment
-
Barkan D, El Touny LH, Michalowski AM, Smith JA, Chu I, Davis AS, et al. Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment. Cancer Res 2010;70:5706-16.
-
(2010)
Cancer Res
, vol.70
, pp. 5706-5716
-
-
Barkan, D.1
El Touny, L.H.2
Michalowski, A.M.3
Smith, J.A.4
Chu, I.5
Davis, A.S.6
-
12
-
-
44449137591
-
TNFR1 signaling and IFN-gamma signaling determine whether T cells induce tumor dormancy or promote multistage carcinogenesis
-
Muller-Hermelink N, Braumuller H, Pichler B, Wieder T, Mailhammer R, Schaak K, et al. TNFR1 signaling and IFN-gamma signaling determine whether T cells induce tumor dormancy or promote multistage carcinogenesis. Cancer Cell 2008;13:507-18.
-
(2008)
Cancer Cell
, vol.13
, pp. 507-518
-
-
Muller-Hermelink, N.1
Braumuller, H.2
Pichler, B.3
Wieder, T.4
Mailhammer, R.5
Schaak, K.6
-
13
-
-
4644341516
-
Discontinuation of imatinib therapy after achieving a molecular response
-
Cortes J, O'Brien S, Kantarjian H. Discontinuation of imatinib therapy after achieving a molecular response. Blood 2004;104:2204-5.
-
(2004)
Blood
, vol.104
, pp. 2204-2205
-
-
Cortes, J.1
O'Brien, S.2
Kantarjian, H.3
-
14
-
-
84863124648
-
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
-
Hamilton A, Helgason GV, Schemionek M, Zhang B, Myssina S, Allan EK, et al. Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival. Blood 2012;119:1501-10.
-
(2012)
Blood
, vol.119
, pp. 1501-1510
-
-
Hamilton, A.1
Helgason, G.V.2
Schemionek, M.3
Zhang, B.4
Myssina, S.5
Allan, E.K.6
-
15
-
-
0029818753
-
Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen
-
Ewald D, Li M, Efrat S, Auer G, Wall RJ, Furth PA, et al. Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen. Science 1996;273:1384-6.
-
(1996)
Science
, vol.273
, pp. 1384-1386
-
-
Ewald, D.1
Li, M.2
Efrat, S.3
Auer, G.4
Wall, R.J.5
Furth, P.A.6
-
16
-
-
0033180211
-
Reversible tumorigenesis by MYC in hematopoietic lineages
-
Felsher DW, Bishop JM. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol Cell 1999;4:199-207.
-
(1999)
Mol Cell
, vol.4
, pp. 199-207
-
-
Felsher, D.W.1
Bishop, J.M.2
-
17
-
-
0035893318
-
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes
-
Fisher GH, Wellen SL, Klimstra D, Lenczowski JM, Tichelaar JW, Lizak MJ, et al. Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. Genes Dev 2001;15:3249-62.
-
(2001)
Genes Dev
, vol.15
, pp. 3249-3262
-
-
Fisher, G.H.1
Wellen, S.L.2
Klimstra, D.3
Lenczowski, J.M.4
Tichelaar, J.W.5
Lizak, M.J.6
-
18
-
-
19044370434
-
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis
-
Moody SE, Sarkisian CJ, Hahn KT, Gunther EJ, Pickup S, Dugan KD, et al. Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis. Cancer Cell 2002;2:451-61.
-
(2002)
Cancer Cell
, vol.2
, pp. 451-461
-
-
Moody, S.E.1
Sarkisian, C.J.2
Hahn, K.T.3
Gunther, E.J.4
Pickup, S.5
Dugan, K.D.6
-
19
-
-
7744220635
-
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
-
Shachaf CM, Kopelman AM, Arvanitis C, Karlsson A, Beer S, Mandl S, et al.MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature 2004;431:1112-7.
-
(2004)
Nature
, vol.431
, pp. 1112-1117
-
-
Shachaf, C.M.1
Kopelman, A.M.2
Arvanitis, C.3
Karlsson, A.4
Beer, S.5
Mandl, S.6
-
20
-
-
10944258521
-
Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation
-
Boxer RB, Jang JW, Sintasath L, Chodosh LA. Lack of sustained regression of c-MYC-induced mammary adenocarcinomas following brief or prolonged MYC inactivation. Cancer Cell 2004;6:577-86.
-
(2004)
Cancer Cell
, vol.6
, pp. 577-586
-
-
Boxer, R.B.1
Jang, J.W.2
Sintasath, L.3
Chodosh, L.A.4
-
21
-
-
42449105650
-
Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras
-
Podsypanina K, Politi K, Beverly LJ, Varmus HE. Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras. Proc Natl Acad Sci U S A 2008;105:5242-7.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 5242-5247
-
-
Podsypanina, K.1
Politi, K.2
Beverly, L.J.3
Varmus, H.E.4
-
22
-
-
10944228766
-
Oncogene addiction: Sometimes a temporary slavery
-
Jonkers J, Berns A. Oncogene addiction: sometimes a temporary slavery. Cancer Cell 2004;6:535-8.
-
(2004)
Cancer Cell
, vol.6
, pp. 535-538
-
-
Jonkers, J.1
Berns, A.2
-
23
-
-
19644376774
-
Tumor dormancy and MYC inactivation: Pushing cancer to the brink of normalcy
-
Shachaf CM, Felsher DW. Tumor dormancy and MYC inactivation: pushing cancer to the brink of normalcy. Cancer Res 2005;65:4471-4.
-
(2005)
Cancer Res
, vol.65
, pp. 4471-4474
-
-
Shachaf, C.M.1
Felsher, D.W.2
-
24
-
-
46349088061
-
Meta-Analyses of chemotherapy for locally advanced and metastatic pancreatic cancer: Results of secondary end points analyses
-
Sultana A, Tudur SC, Cunningham D, Starling N, Neoptolemos JP, Ghaneh P. Meta-Analyses of chemotherapy for locally advanced and metastatic pancreatic cancer: results of secondary end points analyses. Br J Cancer 2008;99:6-13.
-
(2008)
Br J Cancer
, vol.99
, pp. 6-13
-
-
Sultana, A.1
Tudur, S.C.2
Cunningham, D.3
Starling, N.4
Neoptolemos, J.P.5
Ghaneh, P.6
-
25
-
-
0036883940
-
Pancreatic cancer biology and genetics
-
Bardeesy N, DePinho RA. Pancreatic cancer biology and genetics. Nat Rev Cancer 2002;2:897-909.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 897-909
-
-
Bardeesy, N.1
Depinho, R.A.2
-
26
-
-
84863012865
-
Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
-
Collins MA, Bednar F, Zhang Y, Brisset JC, Galban S, Galban CJ, et al. Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice. J Clin Invest 2012;22:639-53.
-
(2012)
J Clin Invest
, vol.22
, pp. 639-653
-
-
Collins, M.A.1
Bednar, F.2
Zhang, Y.3
Brisset, J.C.4
Galban, S.5
Galban, C.J.6
-
27
-
-
84860321700
-
Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
-
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, et al. Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism. Cell 2012;149:656-70.
-
(2012)
Cell
, vol.149
, pp. 656-670
-
-
Ying, H.1
Kimmelman, A.C.2
Lyssiotis, C.A.3
Hua, S.4
Chu, G.C.5
Fletcher-Sananikone, E.6
-
28
-
-
84870709449
-
Metastatic pancreatic cancer is dependent on oncogenic Kras in mice
-
Collins MA, Brisset JC, Zhang Y, Bednar F, Pierre J, Heist KA, et al. Metastatic pancreatic cancer is dependent on oncogenic Kras in mice. PLoS One 2012;7:e49707.
-
(2012)
PLoS One
, vol.7
-
-
Collins, M.A.1
Brisset, J.C.2
Zhang, Y.3
Bednar, F.4
Pierre, J.5
Heist, K.A.6
-
29
-
-
84875425951
-
Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer
-
Lin WC, Rajbhandari N, Liu C, Sakamoto K, Zhang Q, Triplett AA, et al. Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer. Cancer Res 2013;73:1821-30.
-
(2013)
Cancer Res
, vol.73
, pp. 1821-1830
-
-
Lin, W.C.1
Rajbhandari, N.2
Liu, C.3
Sakamoto, K.4
Zhang, Q.5
Triplett, A.A.6
-
30
-
-
84860726170
-
Blockade of JAK2-mediated extrinsic survival signals restores sensitivity of CML cells to ABL inhibitors
-
Traer E, MacKenzie R, Snead J, Agarwal A, Eiring AM, O'Hare T, et al. Blockade of JAK2-mediated extrinsic survival signals restores sensitivity of CML cells to ABL inhibitors. Leukemia 2012;26:1140-3.
-
(2012)
Leukemia
, vol.26
, pp. 1140-1143
-
-
Traer, E.1
Mackenzie, R.2
Snead, J.3
Agarwal, A.4
Eiring, A.M.5
O'Hare, T.6
-
32
-
-
84860342715
-
Pancreatic stellate cells form a niche for cancer stem cells and promote their selfrenewal and invasiveness
-
Lonardo E, Frias-Aldeguer J, Hermann PC, Heeschen C. Pancreatic stellate cells form a niche for cancer stem cells and promote their selfrenewal and invasiveness. Cell Cycle 2012;11:1282-90.
-
(2012)
Cell Cycle
, vol.11
, pp. 1282-1290
-
-
Lonardo, E.1
Frias-Aldeguer, J.2
Hermann, P.C.3
Heeschen, C.4
-
33
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006;127:469-80.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
34
-
-
77951975325
-
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
-
Vermeulen L, De Sousa E Melo, van der Heijden M, Cameron K, de Jong JH, Borovski T, et al.Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nat Cell Biol 2010;12: 468-76.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 468-476
-
-
Vermeulen, L.1
Melo E D.Sousa2
Van Der Heijden, M.3
Cameron, K.4
De Jong, J.H.5
Borovski, T.6
-
35
-
-
0347634454
-
Defining the epithelial stem cell niche in skin
-
Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M, et al. Defining the epithelial stem cell niche in skin. Science 2004;303: 359-63.
-
(2004)
Science
, vol.303
, pp. 359-363
-
-
Tumbar, T.1
Guasch, G.2
Greco, V.3
Blanpain, C.4
Lowry, W.E.5
Rendl, M.6
-
37
-
-
83255177150
-
Single-cell dissection of transcriptional heterogeneity in human colon tumors
-
Dalerba P, Kalisky T, Sahoo D, Rajendran PS, Rothenberg ME, Leyrat AA, et al. Single-cell dissection of transcriptional heterogeneity in human colon tumors. Nat Biotechnol 2011;29:1120-7.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 1120-1127
-
-
Dalerba, P.1
Kalisky, T.2
Sahoo, D.3
Rajendran, P.S.4
Rothenberg, M.E.5
Leyrat, A.A.6
|