Direct analysis of triacylglycerols from crude lipid mixtures by gold nanoparticle-assisted laser desorption/ionization mass spectrometry

Journal of the American Society for Mass Spectrometry

Volumn 25, Issue 5, 2014, Pages 891-894

  Son, Jeongjin ^a   Lee, Gwangbin ^a   Cha, Sangwon ^a  

^a Hankuk University of Foreign Studies   (South Korea)

Author keywords

Gold nanoparticle; Graphene oxide; Laser desorption ionization; Phophatidylcholine; Triacylglycerol

Indexed keywords

DESORPTION; GLYCEROL; GOLD; MASS SPECTROMETRY; METAL NANOPARTICLES; MIXTURES; PHOSPHOLIPIDS;

GOLD NANOPARTICLES; GRAPHENE OXIDES; LASER DESORPTION/IONIZATION; PHOPHATIDYLCHOLINE; TRIACYLGLYCEROLS;

SIGNAL DETECTION;

CITRIC ACID; GENTISIC ACID; GOLD NANOPARTICLE; LIPID; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; TRIACYLGLYCEROL; DRUG MIXTURE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; GOLD; METAL NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BEEF; BRAIN TISSUE; LIMIT OF DETECTION; LIPID ANALYSIS; LIPID BRAIN LEVEL; LIPID COMPOSITION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PROTEIN PURIFICATION; ANIMAL; BOVINE; BRAIN; CHEMISTRY; COMPARATIVE STUDY; DRUG MIXTURE; EVALUATION STUDY; MASS SPECTROMETRY; METABOLISM; PARTICLE SIZE; PIG; REPRODUCIBILITY; SOLUBILITY; SURFACE PROPERTY;

ANIMALS; BRAIN; CATTLE; CITRIC ACID; COMPLEX MIXTURES; GOLD; INDICATORS AND REAGENTS; LIMIT OF DETECTION; METAL NANOPARTICLES; PARTICLE SIZE; REPRODUCIBILITY OF RESULTS; SOLUBILITY; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SURFACE PROPERTIES; SUS SCROFA; TRIGLYCERIDES;

EID: 84899503783     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-014-0844-9     Document Type: Article

References (16)

1. Fuchs, B., Suss, R., Schiller, J.: An update of MALDI-TOF mass spectrometry in lipid research. Prog Lipid Res 49, 450-475 (2010)
2. Petkovic, M., Schiller, J., Muller, M., Benard, S., Reichl, S., Arnold, K., Arnhold, J.: Detection of individual phospholipids in lipid mixtures by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: phosphatidylcholine prevents the detection of further species. Anal Biochem 289, 202-216 (2001)
3. Sun, G., Yang, K., Zhao, Z., Guan, S., Han, X., Gross, R.W.: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of cellular glycerophospholipids enabled by multiplexed solvent dependent analyte-matrix interactions. Anal Chem 80, 7576-7585 (2008)
4. Fuchs, B., Schiller, J., Suess, R., Schuerenberg, M., Suckau, D.: A direct and simple method of coupling matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) to thin-layer chromatography (TLC) for the analysis of phospholipids from egg yolk. Anal Bioanal Chem 389, 827-834 (2007)
5. Emerson, B., Gidden, J., Lay Jr., J.O., Durham, B.: A rapid separation technique for overcoming suppression of triacylglycerols by phosphatidylcholine using MALDI-TOF MS. J Lipid Res 51, 2428-2434 (2010)
6. Cha, S.W., Yeung, E.S.: Colloidal graphite-assisted laser desorption/ionization mass spectrometry and MSn of small molecules. 1. Imaging of cerebrosides directly from rat brain tissue. Anal Chem 79, 2373-2385 (2007)
7. Lee, G., Son, J., Cha, S.: Selective or class-wide mass fingerprinting of phosphatidylcholines and cerebrosides from lipid mixtures by MALDI mass spectrometry. B Korean Chem Soc 34, 2143-2147 (2013)
8. Jackson, S.N., Ugarov, M., Egan, T., Post, J.D., Langlais, D., Schultz, J.A., Woods, A.S.: MALDI-ion mobility-TOFMS imaging of lipids in rat brain tissue. J Mass Spectrom 42, 1093-1098 (2007)
9. Chapagain, B.P., Wiesman, Z.: MALDI-TOF/MS fingerprinting of triacylglycerols (TAGs) in olive oils produced in the Israeli Negev desert. J Agric Food Chem 57, 1135-1142 (2009)
10. Asbury, G.R., Al-Saad, K., Siems, W.F., Hannan, R.M., Hill, H.H.: Analysis of triacylglycerols and whole oils by matrix-assisted laser desorption/ionization time of flight mass spectrometry. J Am Soc Mass Spectrom 10, 983-991 (1999)
11. Teuber, K., Schiller, J., Fuchs, B., Karas, M., Jaskolla, T.W.: Significant sensitivity improvements by matrix optimization: a MALDI-TOF mass spectrometric study of lipids from hen egg yolk. Chem Phys Lipids 163, 552-560 (2010)
12. Kaufman, M., Wiesman, Z.: Pomegranate oil analysis with emphasis on MALDI-TOF/MS triacylglycerol fingerprinting. J Agric Food Chem 55, 10405-10413 (2007)
13. Jackson, S., Baldwin, K., Muller, L., Womack, V., Schultz, J.A., Balaban, C., Woods, A.: Imaging of lipids in rat heart by MALDI-MS with silver nanoparticles. Anal Bioanal Chem 406, 1377-1386 (2014)
14. Cook, H.W.: Metabolism of triacylglycerol in developing rat brain. Neurochem Res 6, 1217-1229 (1981)
15. Cheng, C., Gross, M.L., Pittenauer, E.: Complete structural elucidation of triacylglycerols by tandem sector mass spectrometry. Anal Chem 70, 4417-4426 (1998)
16. Pittenauer, E., Allmaier, G.: The renaissance of high-energy CID for structural elucidation of complex lipids: MALDI-TOF/RTOF-MS of alkali cationized triacylglycerols. J Am Soc Mass Spectrom 20, 1037-1047 (2009)