Erratum: (Arteriosclerosis, Thrombosis, and Vascular Biology (2014) 34 (1045-1056) DOI 10.1161/ATVBAHA.113.302943);Disseminated arterial calcification and enhanced myogenic response are associated with Abcc6 deficiency in a mouse model of pseudoxanthoma elasticum

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 5, 2014, Pages 1045-1056

  Kauffenstein, Gilles ^a,f   Pizard, A ^b   Corre, Y Le ^a   Vessieres E ^a   Grimaud, L ^a   Toutain, B ^a   Labat, C ^b   Mauras, Y ^a   Gorgels, T G ^d   Bergen, A A ^d,e   Saux, O Le ^c   Lacolley, P ^b   Leftheriotis G ^a   Henrion, D ^a   Martin, L ^a  

^a ANGERS UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

^c UNIVERSITY OF HAWAII   (United States)

^d NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

^f INSERM   (France)

Author keywords

ABC transporters; arteriosclerosis; calcification, physiologic

Indexed keywords

ALIZARIN; CALCIUM; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 6; OSTEOPONTIN; PHENYLEPHRINE; THROMBOXANE A2; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9;

ALIZARIN RED STAINING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTERIAL STIFFNESS; ARTERIOSCLEROSIS; ARTERY CALCIFICATION; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BLOOD FLOW; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR PARAMETERS; CAROTID ARTERY; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; ELASTIC FIBER; GENE EXPRESSION; IN VITRO STUDY; MORPHOMETRICS; MOUSE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 6 DEFICIENCY; MUSCLE ISOMETRIC CONTRACTION; MYOGRAPHY; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PSEUDOXANTHOMA ELASTICUM; STAINING; TISSUE DIFFERENTIATION; VASCULARIZATION; VASOCONSTRICTION; WILD TYPE;

ABC TRANSPORTERS; ARTERIOSCLEROSIS; CALCIFICATION, PHYSIOLOGIC;

ANIMALS; ARTERIAL PRESSURE; ARTERIES; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL MARKERS; CALCIUM; CELL TRANSDIFFERENTIATION; CHONDROGENESIS; COLLAGEN TYPE II; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DISEASE MODELS, ANIMAL; ELASTIC TISSUE; GENE EXPRESSION REGULATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OSTEOGENESIS; OSTEOPONTIN; PSEUDOXANTHOMA ELASTICUM; REGIONAL BLOOD FLOW; RNA, MESSENGER; SOXB1 TRANSCRIPTION FACTORS; VASCULAR CALCIFICATION; VASCULAR STIFFNESS; VASOCONSTRICTION;

EID: 84899496927     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATV.0000000000000017     Document Type: Erratum

References (46)

1. Neldner KH. Pseudoxanthoma elasticum. Clin Dermatol. 1988;6:1-159.
2. Li Q, Jiang Q, Pfendner E, Váradi A, Uitto J. Pseudoxanthoma elasticum: clinical phenotypes, molecular genetics and putative pathomechanisms. Exp Dermatol. 2009;18:1-11.
3. Pomozi V, Le Saux O, Brampton C, Apana A, Iliás A, Szeri F, Martin L, Monostory K, Paku S, Sarkadi B, Szakács G, Váradi A. ABCC6 is a basolateral plasma membrane protein. Circ Res. 2013;112:e148-e151.
4. Kévorkian JP, Masquet C, Kural-Ménasché S, Le Dref O, Beaufils P. New report of severe coronary artery disease in an eighteen-year-old girl with pseudoxanthoma elasticum. Case report and review of the literature. Angiology. 1997;48:735-741.
5. Trip MD, Smulders YM, Wegman JJ, Hu X, Boer JM, ten Brink JB, Zwinderman AH, Kastelein JJ, Feskens EJ, Bergen AA. Frequent mutation in the ABCC6 gene (R1141X) is associated with a strong increase in the prevalence of coronary artery disease. Circulation. 2002;106:773-775.
6. Chassaing N, Martin L, Calvas P, Le Bert M, Hovnanian A. Pseudoxanthoma elasticum: a clinical, pathophysiological and genetic update including 11 novel ABCC6 mutations. J Med Genet. 2005;42:881-892.
7. Boutouyrie P, Germain DP, Tropeano AI, Laloux B, Carenzi F, Zidi M, Jeunemaitre X, Laurent S. Compressibility of the carotid artery in patients with pseudoxanthoma elasticum. Hypertension. 2001;38:1181-1184.
8. Germain DP, Boutouyrie P, Laloux B, Laurent S. Arterial remodeling and stiffness in patients with pseudoxanthoma elasticum. Arterioscler Thromb Vasc Biol. 2003;23:836-841.
9. Kornet L, Bergen AA, Hoeks AP, Cleutjens JP, Oostra RJ, Daemen MJ, van Soest S, Reneman RS. In patients with pseudoxanthoma elasticum a thicker and more elastic carotid artery is associated with elastin fragmentation and proteoglycans accumulation. Ultrasound Med Biol. 2004;30:1041-1048.
10. Passi A, Albertini R, Baccarani Contri M, de Luca G, de Paepe A, Pallavicini G, Pasquali Ronchetti I, Tiozzo R. Proteoglycan alterations in skin fibroblast cultures from patients affected with pseudoxanthoma elasticum. Cell Biochem Funct. 1996;14:111-120.
11. Lefthériotis G, Abraham P, Le Corre Y, Le Saux O, Henrion D, Ducluzeau PH, Prunier F, Martin L. Relationship between ankle brachial index and arterial remodeling in pseudoxanthoma elasticum. J Vasc Surg. 2011;54:1390-1394.
12. Perdu J, Champion K, Emmerich J, Fiessinger JN. [Microvascular involvement in pseudoxanthoma elasticum. Capillaroscopic findings]. Presse Med. 2004;33:518-521.
13. Gorgels TG, Hu X, Scheffer GL, van der Wal AC, Toonstra J, de Jong PT, van Kuppevelt TH, Levelt CN, de Wolf A, Loves WJ, Scheper RJ, Peek R, Bergen AA. Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum. Hum Mol Genet. 2005;14:1763-1773.
14. Klement JF, Matsuzaki Y, Jiang QJ, Terlizzi J, Choi HY, Fujimoto N, Li K, Pulkkinen L, Birk DE, Sundberg JP, Uitto J. Targeted ablation of the abcc6 gene results in ectopic mineralization of connective tissues. Mol Cell Biol. 2005;25:8299-8310.
15. Le Corre Y, Le Saux O, Froeliger F, Libouban H, Kauffenstein G, Willoteaux S, Leftheriotis G, Martin L. Quantification of the calcification phenotype of Abcc6-deficient mice with microcomputed tomography. Am J Pathol. 2012;180:2208-2213.
16. Mellander S. Functional aspects of myogenic vascular control. J Hypertens Suppl. 1989;7:S21-S30; discussion S31.
17. Schafer C, Heiss A, Schwarz A, Westenfeld R, Ketteler M, Floege J, Muller-Esterl W, Schinke T, Jahnen-Dechent W. The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification. J Clin Invest. 2003;112:357-366.
18. Luo G, Ducy P, McKee MD, Pinero GJ, Loyer E, Behringer RR, Karsenty G. Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature. 1997;386:78-81.
19. Wada T, McKee MD, Steitz S, Giachelli CM. Calcification of vascular smooth muscle cell cultures: inhibition by osteopontin. Circ Res. 1999;84:166-178.
20. Rutsch F, Nitschke Y, Terkeltaub R. Genetics in arterial calcification: pieces of a puzzle and cogs in a wheel. Circ Res. 2011;109:578-592.
21. Sage AP, Tintut Y, Demer LL. Regulatory mechanisms in vascular calcification. Nat Rev Cardiol. 2010;7:528-536.
22. Aherrahrou Z, Axtner SB, Kaczmarek PM, Jurat A, Korff S, Doehring LC, Weichenhan D, Katus HA, Ivandic BT. A locus on chromosome 7 determines dramatic up-regulation of osteopontin in dystrophic cardiac calcification in mice. Am J Pathol. 2004;164:1379-1387.
23. Sowa AK, Kaiser FJ, Eckhold J, Kessler T, Aherrahrou R, Wrobel S, Kaczmarek PM, Doehring L, Schunkert H, Erdmann J, Aherrahrou Z. Functional interaction of osteogenic transcription factors Runx2 and Vdr in transcriptional regulation of Opn during soft tissue calcification. Am J Pathol. 2013;183:60-68.
24. Prince CW, Butler WT. 1,25-Dihydroxyvitamin D3 regulates the biosynthesis of osteopontin, a bone-derived cell attachment protein, in clonal osteoblast-like osteosarcoma cells. Coll Relat Res. 1987;7:305-313.
25. Shen Q, Christakos S. The vitamin D receptor, Runx2, and the Notch signaling pathway cooperate in the transcriptional regulation of osteopontin. J Biol Chem. 2005;280:40589-40598.
26. Bell DM, Leung KK, Wheatley SC, Ng LJ, Zhou S, Ling KW, Sham MH, Koopman P, Tam PP, Cheah KS. SOX9 directly regulates the type-II collagen gene. Nat Genet. 1997;16:174-178.
27. Speer MY, Yang HY, Brabb T, Leaf E, Look A, Lin WL, Frutkin A, Dichek D, Giachelli CM. Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries. Circ Res. 2009;104:733-741.
28. Xu Z, Ji G, Shen J, Wang X, Zhou J, Li L. SOX9 and myocardin counteract each other in regulating vascular smooth muscle cell differentiation. Biochem Biophys Res Commun. 2012;422:285-290.
29. Vanakker OM, Martin L, Schurgers LJ, Quaglino D, Costrop L, Vermeer C, Pasquali-Ronchetti I, Coucke PJ, De Paepe A. Low serum vitamin K in PXE results in defective carboxylation of mineralization inhibitors similar to the GGCX mutations in the PXE-like syndrome. Lab Invest. 2010;90:895-905.
30. St Hilaire C, Ziegler SG, Markello TC, et al. NT5E mutations and arterial calcifications. N Engl J Med. 2011;364:432-442.
31. Markello TC, Pak LK, St Hilaire C, Dorward H, Ziegler SG, Chen MY, Chaganti K, Nussbaum RL, Boehm M, Gahl WA. Vascular pathology of medial arterial calcifications in NT5E deficiency: implications for the role of adenosine in pseudoxanthoma elasticum. Mol Genet Metab. 2011;103:44-50.
32. Szabó Z, Váradi A, Li Q, Uitto J. ABCC6 does not transport adenosine - relevance to pathomechanism of pseudoxanthoma elasticum. Mol Genet Metab. 2011;104:421; author reply 422.
33. -/- mice, a model for pseudoxanthoma elasticum. Matrix Biol. 2012;31:246-252.
34. Demer LL, Tintut Y. Vascular calcification: pathobiology of a multifaceted disease. Circulation. 2008;117:2938-2948.
35. Le Saux O, Urban Z, Tschuch C, Csiszar K, Bacchelli B, Quaglino D, Pasquali-Ronchetti I, Pope FM, Richards A, Terry S, Bercovitch L, de Paepe A, Boyd CD. Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum. Nat Genet. 2000;25:223-227.
36. Jansen RS, Küçükosmanoglu A, de Haas M, Sapthu S, Otero JA, Hegman IE, Bergen AA, Gorgels TG, Borst P, van de Wetering K. ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release. Proc Natl Acad Sci USA. 2013;110:20206-20211.
37. Osborne-Pellegrin M, Labat C, Mercier N, Challande P, Lacolley P. Changes in aortic stiffness related to elastic fiber network anomalies in the Brown Norway rat during maturation and aging. Am J Physiol Heart Circ Physiol. 2010;299:H144-H152.
38. Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation. 2004;109:III27-32.
39. Kauffenstein G, Laher I, Matrougui K, Guérineau NC, Henrion D. Emerging role of G protein-coupled receptors in microvascular myogenic tone. Cardiovasc Res. 2012;95:223-232.
40. Dubroca C, Lacombe P, Domenga V, Maciazek J, Levy B, Tournier-Lasserve E, Joutel A, Henrion D. Impaired vascular mechanotransduction in a transgenic mouse model of CADASIL arteriopathy. Stroke. 2005;36:113-117.
41. Khavandi K, Greenstein AS, Sonoyama K, Withers S, Price A, Malik RA, Heagerty AM. Myogenic tone and small artery remodelling: insight into diabetic nephropathy. Nephrol Dial Transplant. 2009;24: 361-369.
42. Sakata K, Nakamura T, Tamekiyo H, Obayashi K, Ishikawa J, Nawada R, Yoshida H, Shirotani M. Pseudoxanthoma elasticum with dipyridamole-induced coronary artery spasm: a case report. Jpn Circ J. 1999;63:806-808.
43. Gschwend S, Henning RH, Pinto YM, de Zeeuw D, van Gilst WH, Buikema H. Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade. Br J Pharmacol. 2003;139:1317-1325.
44. Burnstock G, Ralevic V. Purinergic signaling and blood vessels in health and disease. Pharmacol Rev. 2014;66:102-192.
45. Prunier F, Terrien G, Le Corre Y, Apana AL, Biere L, Kauffenstein G, Furber A, Bergen ABA, Gorgels TGMF, Le Saux O, Leftheriotis G, Martin L. Pseudoxanthoma elasticum: cardiac findings in patients and Abcc6- deficient mouse model. PLoS One. 2013;8:e68700.
46. Nitschke Y, Baujat G, Botschen U, et al. Generalized arterial calcification of infancy and pseudoxanthoma elasticum can be caused by mutations in either ENPP1 or ABCC6. Am J Hum Genet. 2012;90:25-39.