-
1
-
-
84882765340
-
Emerging options for the management of non-small cell lung cancer
-
D. Binder, and K. Hegenbarth Emerging options for the management of non-small cell lung cancer Clin. Med. Insights Oncol. 7 2013 221 234
-
(2013)
Clin. Med. Insights Oncol.
, vol.7
, pp. 221-234
-
-
Binder, D.1
Hegenbarth, K.2
-
2
-
-
79251473704
-
Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth
-
J. Lin, M.C. Haffner, Y. Zhang, B.H. Lee, W.N. Brennen, and J. Britton et al. Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth Prostate 71 2011 333 343
-
(2011)
Prostate
, vol.71
, pp. 333-343
-
-
Lin, J.1
Haffner, M.C.2
Zhang, Y.3
Lee, B.H.4
Brennen, W.N.5
Britton, J.6
-
3
-
-
77952829803
-
Disulfiram treatment facilitates phosphoinositide 3-kinase inhibition in human breast cancer cells in vitro and in vivo
-
H. Zhang, D. Chen, J. Ringler, W. Chen, Q.C. Cui, and S.P. Ethier et al. Disulfiram treatment facilitates phosphoinositide 3-kinase inhibition in human breast cancer cells in vitro and in vivo Cancer Res. 70 2010 3996 4004
-
(2010)
Cancer Res.
, vol.70
, pp. 3996-4004
-
-
Zhang, H.1
Chen, D.2
Ringler, J.3
Chen, W.4
Cui, Q.C.5
Ethier, S.P.6
-
4
-
-
75749092675
-
Disulfiram induces copper-dependent stimulation of reactive oxygen species and activation of the extrinsic apoptotic pathway in melanoma
-
B.W. Morrison, N.A. Doudican, K.R. Patel, and S.J. Orlow Disulfiram induces copper-dependent stimulation of reactive oxygen species and activation of the extrinsic apoptotic pathway in melanoma Melanoma Res. 20 2010 11 20
-
(2010)
Melanoma Res.
, vol.20
, pp. 11-20
-
-
Morrison, B.W.1
Doudican, N.A.2
Patel, K.R.3
Orlow, S.J.4
-
5
-
-
84867897977
-
Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells
-
P. Liu, S. Brown, T. Goktug, P. Channathodiyil, V. Kannappan, and J.P. Hugnot et al. Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells Br. J. Cancer 107 2012 1488 1497
-
(2012)
Br. J. Cancer
, vol.107
, pp. 1488-1497
-
-
Liu, P.1
Brown, S.2
Goktug, T.3
Channathodiyil, P.4
Kannappan, V.5
Hugnot, J.P.6
-
6
-
-
84878660014
-
The role of copper in disulfiram-induced toxicity and radiosensitization of cancer cells
-
C. Rae, M. Tesson, J.W. Babich, M. Boyd, A. Sorensen, and R.J. Mairs The role of copper in disulfiram-induced toxicity and radiosensitization of cancer cells J. Nucl. Med. 54 2013 953 960
-
(2013)
J. Nucl. Med.
, vol.54
, pp. 953-960
-
-
Rae, C.1
Tesson, M.2
Babich, J.W.3
Boyd, M.4
Sorensen, A.5
Mairs, R.J.6
-
7
-
-
84877117741
-
Degradation of NF-kappaB, p53 and other regulatory redox-sensitive proteins by thiol-conjugating and -nitrosylating drugs in human tumor cells
-
A. Paranjpe, and K.S. Srivenugopal Degradation of NF-kappaB, p53 and other regulatory redox-sensitive proteins by thiol-conjugating and -nitrosylating drugs in human tumor cells Carcinogenesis 34 2013 990 1000
-
(2013)
Carcinogenesis
, vol.34
, pp. 990-1000
-
-
Paranjpe, A.1
Srivenugopal, K.S.2
-
8
-
-
79955805229
-
Disulfiram modulated ROS-MAPK and NFkappaB pathways and targeted breast cancer cells with cancer stem cell-like properties
-
N.C. Yip, I.S. Fombon, P. Liu, S. Brown, V. Kannappan, and A.L. Armesilla et al. Disulfiram modulated ROS-MAPK and NFkappaB pathways and targeted breast cancer cells with cancer stem cell-like properties Br. J. Cancer 104 2011 1564 1574
-
(2011)
Br. J. Cancer
, vol.104
, pp. 1564-1574
-
-
Yip, N.C.1
Fombon, I.S.2
Liu, P.3
Brown, S.4
Kannappan, V.5
Armesilla, A.L.6
-
9
-
-
82955234022
-
Disulfiram/copper complex activated JNK/c-jun pathway and sensitized cytotoxicity of doxorubicin in doxorubicin resistant leukemia HL60 cells
-
B. Xu, P. Shi, I.S. Fombon, Y. Zhang, F. Huang, and W. Wang et al. Disulfiram/copper complex activated JNK/c-jun pathway and sensitized cytotoxicity of doxorubicin in doxorubicin resistant leukemia HL60 cells Blood Cells Mol. Dis. 47 2011 264 269
-
(2011)
Blood Cells Mol. Dis.
, vol.47
, pp. 264-269
-
-
Xu, B.1
Shi, P.2
Fombon, I.S.3
Zhang, Y.4
Huang, F.5
Wang, W.6
-
10
-
-
79954999526
-
Copper binding agents acting as copper ionophores lead to caspase inhibition and paraptotic cell death in human cancer cells
-
S. Tardito, I. Bassanetti, C. Bignardi, L. Elviri, M. Tegoni, and C. Mucchino et al. Copper binding agents acting as copper ionophores lead to caspase inhibition and paraptotic cell death in human cancer cells J. Am. Chem. Soc. 133 2011 6235 6242
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 6235-6242
-
-
Tardito, S.1
Bassanetti, I.2
Bignardi, C.3
Elviri, L.4
Tegoni, M.5
Mucchino, C.6
-
11
-
-
84861172244
-
The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells
-
M. Nagai, N.H. Vo, L. Shin Ogawa, D. Chimmanamada, T. Inoue, and J. Chu et al the oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells Free Radic. Biol. Med. 52 2012 2142 2150
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 2142-2150
-
-
Nagai, M.1
Vo, N.H.2
Shin Ogawa, L.3
Chimmanamada, D.4
Inoue, T.5
Chu, J.6
-
12
-
-
77955645489
-
Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry
-
F. Wang, P. Jiao, M. Qi, M. Frezza, Q.P. Dou, and B. Yan Turning tumor-promoting copper into an anti-cancer weapon via high-throughput chemistry Curr. Med. Chem. 17 2010 2685 2698
-
(2010)
Curr. Med. Chem.
, vol.17
, pp. 2685-2698
-
-
Wang, F.1
Jiao, P.2
Qi, M.3
Frezza, M.4
Dou, Q.P.5
Yan, B.6
-
13
-
-
84870329756
-
The cancer stem-cell hypothesis: Its emerging role in lung cancer biology and its relevance for future therapy
-
J.D. O'Flaherty, M. Barr, D. Fennell, D. Richard, J. Reynolds, and J. O'Leary et al the cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy J. Thorac. Oncol. 7 2012 1880 1890
-
(2012)
J. Thorac. Oncol.
, vol.7
, pp. 1880-1890
-
-
O'Flaherty, J.D.1
Barr, M.2
Fennell, D.3
Richard, D.4
Reynolds, J.5
O'Leary, J.6
-
14
-
-
84871880164
-
Cancer stem cells in solid tumors: An overview and new approaches for their isolation and characterization
-
V. Tirino, V. Desiderio, F. Paino, A. De Rosa, F. Papaccio, and M. La Noce et al. Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterization FASEB J. 27 2013 13 24
-
(2013)
FASEB J.
, vol.27
, pp. 13-24
-
-
Tirino, V.1
Desiderio, V.2
Paino, F.3
De Rosa, A.4
Papaccio, F.5
La Noce, M.6
-
15
-
-
84897435105
-
Use of disulfiram and risk of cancer: A population-based case-control study
-
G. Askgaard, S. Friis, J. Hallas, L.C. Thygesen, and A. Pottegard Use of disulfiram and risk of cancer: a population-based case-control study Eur. J. Cancer Prev. 23 2014 225 232
-
(2014)
Eur. J. Cancer Prev.
, vol.23
, pp. 225-232
-
-
Askgaard, G.1
Friis, S.2
Hallas, J.3
Thygesen, L.C.4
Pottegard, A.5
-
16
-
-
84865563465
-
Disulfiram, an old drug with new potential therapeutic uses for human hematological malignancies
-
C. Conticello, D. Martinetti, L. Adamo, S. Buccheri, R. Giuffrida, and N. Parrinello et al. Disulfiram, an old drug with new potential therapeutic uses for human hematological malignancies Int. J. Cancer 131 2012 2197 2203
-
(2012)
Int. J. Cancer
, vol.131
, pp. 2197-2203
-
-
Conticello, C.1
Martinetti, D.2
Adamo, L.3
Buccheri, S.4
Giuffrida, R.5
Parrinello, N.6
-
17
-
-
33845304732
-
Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients
-
M. Wickstrom, K. Danielsson, L. Rickardson, J. Gullbo, P. Nygren, and A. Isaksson et al. Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients Biochem. Pharmacol. 73 2007 25 33
-
(2007)
Biochem. Pharmacol.
, vol.73
, pp. 25-33
-
-
Wickstrom, M.1
Danielsson, K.2
Rickardson, L.3
Gullbo, J.4
Nygren, P.5
Isaksson, A.6
-
18
-
-
84869482208
-
New applications of old metal-binding drugs in the treatment of human cancer
-
S.M. Schmitt, M. Frezza, and Q.P. Dou New applications of old metal-binding drugs in the treatment of human cancer Front. Biosci. (Schol Ed). 4 2012 375 391
-
(2012)
Front. Biosci. (Schol Ed).
, vol.4
, pp. 375-391
-
-
Schmitt, S.M.1
Frezza, M.2
Dou, Q.P.3
-
19
-
-
84895819755
-
Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage
-
A. Paranjpe, R. Zhang, F. Ali-Osman, G.C. Bobustuc, and K.S. Srivenugopal Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage Carcinogenesis 35 2014 692 702
-
(2014)
Carcinogenesis
, vol.35
, pp. 692-702
-
-
Paranjpe, A.1
Zhang, R.2
Ali-Osman, F.3
Bobustuc, G.C.4
Srivenugopal, K.S.5
-
20
-
-
0036221429
-
Oxidative damage due to copper ion and hydrogen peroxide induces GlcNAc-specific cleavage of an Asn-linked oligosaccharide
-
H. Eguchi, Y. Ikeda, S. Koyota, K. Honke, K. Suzuki, and J.M. Gutteridge et al. Oxidative damage due to copper ion and hydrogen peroxide induces GlcNAc-specific cleavage of an Asn-linked oligosaccharide J. Biochem. 131 2002 477 484
-
(2002)
J. Biochem.
, vol.131
, pp. 477-484
-
-
Eguchi, H.1
Ikeda, Y.2
Koyota, S.3
Honke, K.4
Suzuki, K.5
Gutteridge, J.M.6
-
21
-
-
84866466140
-
Diethyldithiocarbamate complex with copper: The mechanism of action in cancer cells
-
Z. Skrott, and B. Cvek Diethyldithiocarbamate complex with copper: the mechanism of action in cancer cells Mini Rev. Med. Chem. 12 2012 1184 1192
-
(2012)
Mini Rev. Med. Chem.
, vol.12
, pp. 1184-1192
-
-
Skrott, Z.1
Cvek, B.2
-
22
-
-
84865675396
-
Enhancement of cisplatin cytotoxicity by disulfiram involves activating transcription factor 3
-
A. O'Brien, J.E. Barber, S. Reid, N. Niknejad, and J. Dimitroulakos Enhancement of cisplatin cytotoxicity by disulfiram involves activating transcription factor 3 Anticancer Res. 32 2012 2679 2688
-
(2012)
Anticancer Res.
, vol.32
, pp. 2679-2688
-
-
O'Brien, A.1
Barber, J.E.2
Reid, S.3
Niknejad, N.4
Dimitroulakos, J.5
-
23
-
-
84862229701
-
Matrix metalloproteinase-2 and -9 in glioblastoma: A trio of old drugs-captopril, disulfiram and nelfinavir-are inhibitors with potential as adjunctive treatments in glioblastoma
-
R.E. Kast, and M.E. Halatsch Matrix metalloproteinase-2 and -9 in glioblastoma: a trio of old drugs-captopril, disulfiram and nelfinavir-are inhibitors with potential as adjunctive treatments in glioblastoma Arch. Med. Res. 43 2012 243 247
-
(2012)
Arch. Med. Res.
, vol.43
, pp. 243-247
-
-
Kast, R.E.1
Halatsch, M.E.2
-
24
-
-
79951688311
-
Targeting malignancies with disulfiram (Antabuse): Multidrug resistance, angiogenesis, and proteasome
-
B. Cvek Targeting malignancies with disulfiram (Antabuse): multidrug resistance, angiogenesis, and proteasome Curr. Cancer Drug Targets 11 2011 332 337
-
(2011)
Curr. Cancer Drug Targets
, vol.11
, pp. 332-337
-
-
Cvek, B.1
-
25
-
-
84872773175
-
Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide
-
J. Triscott, C. Lee, K. Hu, A. Fotovati, R. Berns, and M. Pambid et al. Disulfiram, a drug widely used to control alcoholism, suppresses the self-renewal of glioblastoma and over-rides resistance to temozolomide Oncotarget 3 2012 1112 1123
-
(2012)
Oncotarget
, vol.3
, pp. 1112-1123
-
-
Triscott, J.1
Lee, C.2
Hu, K.3
Fotovati, A.4
Berns, R.5
Pambid, M.6
|