-
1
-
-
0000925297
-
A drug sensitizing the organism to ethyl alcohol
-
Hald J, Jacobsen E. A drug sensitizing the organism to ethyl alcohol. Lancet. 1948;2:1001-1004.
-
(1948)
Lancet
, vol.2
, pp. 1001-1004
-
-
Hald, J.1
Jacobsen, E.2
-
2
-
-
0035794002
-
2+ complex
-
DOI 10.1016/S0014-2999(01)00792-0, PII S0014299901007920
-
Chen SH, Liu SH, Liang YC, Lin JK, Lin-Shiau SY. Oxidative stress and c-Jun-amino-terminal kinase activation involved in apoptosis of primary astrocytes induced by disulfiram-Cu2+ complex. Eur J Pharmacol. 2001;414:177-188. (Pubitemid 32181884)
-
(2001)
European Journal of Pharmacology
, vol.414
, Issue.2-3
, pp. 177-188
-
-
Chen, S.H.1
Liu, S.H.2
Liang, Y.-C.3
Lin, J.-K.4
Lin-Shiau, S.-Y.5
-
3
-
-
0036050582
-
Disulfiram induces apoptosis in human melanoma cells: A redox-related process
-
Cen D, Gonzalez RI, Buckmeier JA, Kahlon RS, Tohidian NB, Meyskens FL Jr. Disulfiram induces apoptosis in human melanoma cells: a redox-related process. Mol Cancer Ther. 2002;1:197-204.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 197-204
-
-
Cen, D.1
Gonzalez, R.I.2
Buckmeier, J.A.3
Kahlon, R.S.4
Tohidian, N.B.5
Meyskens Jr., F.L.6
-
4
-
-
33751285781
-
Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity
-
DOI 10.1158/0008-5472.CAN-06-2126
-
Chen D, Cui QC, Yang H, Dou QP. Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity. Cancer Res. 2006;66:10425-10433. (Pubitemid 44799763)
-
(2006)
Cancer Research
, vol.66
, Issue.21
, pp. 10425-10433
-
-
Chen, D.1
Cui, Q.C.2
Yang, H.3
Dou, Q.P.4
-
5
-
-
33644549964
-
Inhibition of proteasome activity, nuclear factor-KB translocation and cell survival by the antialcoholism drug disulfiram
-
Lovborg H, Oberg F, Rickardson L, Gullbo J, Nygren P, Larsson R. Inhibition of proteasome activity, nuclear factor-KB translocation and cell survival by the antialcoholism drug disulfiram. Int J Cancer. 2006;118:1577-1580.
-
(2006)
Int J Cancer
, vol.118
, pp. 1577-1580
-
-
Lovborg, H.1
Oberg, F.2
Rickardson, L.3
Gullbo, J.4
Nygren, P.5
Larsson, R.6
-
6
-
-
48149090212
-
The value of proteasome inhibition in cancer: Can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor?
-
Cvek B, Dvorak Z. The value of proteasome inhibition in cancer: can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor? Drug Discov Today. 2008;13:716-722.
-
(2008)
Drug Discov Today
, vol.13
, pp. 716-722
-
-
Cvek, B.1
Dvorak, Z.2
-
7
-
-
0037457481
-
Disulfiram-mediated inhibition of NF-κb activity enhances cytotoxicity of 5-fluorouracil in human colorectal cancer cell lines
-
DOI 10.1002/ijc.10972
-
Wang W, McLeod HL, Cassidy J. Disulfiram-mediated inhibition of NF-κB activity enhances cytotoxicity of 5-fluorouracil in human colorectal cancer cell lines. Int J Cancer. 2003;104:504-511. (Pubitemid 36323923)
-
(2003)
International Journal of Cancer
, vol.104
, Issue.4
, pp. 504-511
-
-
Wang, W.1
McLeod, H.L.2
Cassidy, J.3
-
8
-
-
77249117637
-
Disulfiram/copper complex inhibiting NFκB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines
-
Guo X, Xu B, Pandey S, et al. Disulfiram/copper complex inhibiting NFκB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines. Cancer Lett. 2010;290:104-113.
-
(2010)
Cancer Lett
, vol.290
, pp. 104-113
-
-
Guo, X.1
Xu, B.2
Pandey, S.3
-
9
-
-
0026447935
-
Long-term Antabuse treatment: Tolerance and reasons for withdrawal
-
Børup C, Kaiser A, Jensen E. Long-term Antabuse treatment: tolerance and reasons for withdrawal. Acta Psychiatr Scand Suppl. 1992;369:47-49.
-
(1992)
Acta Psychiatr Scand Suppl
, vol.369
, pp. 47-49
-
-
Børup, C.1
Kaiser, A.2
Jensen, E.3
-
10
-
-
34249781706
-
Copper-binding compounds as proteasome inhibitors and apoptosis inducers in human cancer
-
DOI 10.2741/2054
-
Daniel KG, Chen D, Yan B, Dou QP. Copper-binding compounds as proteasome inhibitors and apoptosis inducers in human cancer. Front Biosci. 2007;12:135-144. (Pubitemid 46852833)
-
(2007)
Frontiers in Bioscience
, vol.12
, Issue.1
, pp. 135-144
-
-
Daniel, K.G.1
Chen, D.2
Yan, B.3
Ping, D.Q.4
-
11
-
-
58549089871
-
Elevated copper and oxidative stress in cancer cells as a target for cancer treatment
-
Gupte A, Mumper RJ. Elevated copper and oxidative stress in cancer cells as a target for cancer treatment. Cancer Treat Rev. 2009;35:32-46.
-
(2009)
Cancer Treat Rev
, vol.35
, pp. 32-46
-
-
Gupte, A.1
Mumper, R.J.2
-
12
-
-
0025115736
-
Abnormally high expression of proteasomes in human leukemic cells
-
Kumatori A, Tanaka K, Inamura N, Sone S, Ogura T, Matsumoto T. Abnormally high expression of proteasomes in human leukemic cells. Proc Natl Acad Sci USA. 1990;87:7071-7075.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 7071-7075
-
-
Kumatori, A.1
Tanaka, K.2
Inamura, N.3
Sone, S.4
Ogura, T.5
Matsumoto, T.6
-
13
-
-
0141645624
-
The role of the ubiquitin/proteasome system in cellular responses to radiation
-
DOI 10.1038/sj.onc.1206676
-
McBride WH, Iwamoto KS, Syljuasen R, Pervan M, Pajonk F. The role of the ubiquitin/proteasome system in cellular responses to radiation. Oncogene. 2003;22:5755-5773. (Pubitemid 37176698)
-
(2003)
Oncogene
, vol.22
, Issue.37 REV. ISS. 3
, pp. 5755-5773
-
-
McBride, W.H.1
Iwamoto, K.S.2
Syljuasen, R.3
Pervan, M.4
Pajonk, F.5
-
14
-
-
0018333505
-
Diethyldithocarbamate enhancement of radiation and hyperthermic effects on Chinese Hamster cells in vitro
-
DOI 10.2307/3575161
-
Lin PS, Kwock L, Butterfield CE. Diethylthiocarbamate enhancement of radiation and hyperthermic effects on Chinese hamster cell in vitro. Radiat Res. 1979;77:501-511. (Pubitemid 9158697)
-
(1979)
Radiation Research
, vol.77
, Issue.3
, pp. 501-511
-
-
Lin, P.S.1
Kwock, L.2
Butterfield, C.E.3
-
15
-
-
0141958084
-
131I-MIBG is effective for disease palliation in highly refractory neuroblastoma
-
131I-MIBG is effective for disease palliation in highly refractory neuroblastoma. J Pediatr Hematol Oncol. 2003;25:769-773.
-
(2003)
J Pediatr Hematol Oncol
, vol.25
, pp. 769-773
-
-
Kang, T.I.1
Brophy, P.2
Hickeson, M.3
-
17
-
-
0034616637
-
Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism
-
Loo TW, Clarke DM. Blockage of drug resistance in vitro by disulfiram, a drug used to treat alcoholism. J Natl Cancer Inst. 2000;92:898-902. (Pubitemid 30429189)
-
(2000)
Journal of the National Cancer Institute
, vol.92
, Issue.11
, pp. 898-902
-
-
Loo, T.W.1
Clarke, D.M.2
-
18
-
-
0029939666
-
Diagnosis and reversal of multidrug resistance in pediatric cancers
-
Chan HS, Grogan TM, DeBoer G, Haddad G, Gallie BL, Ling V. Diagnosis and reversal of multidrug resistance in pediatric cancers. Eur J Cancer. 1996;32:1051-1061.
-
(1996)
Eur J Cancer
, vol.32
, pp. 1051-1061
-
-
Chan, H.S.1
Grogan, T.M.2
DeBoer, G.3
Haddad, G.4
Gallie, B.L.5
Ling, V.6
-
19
-
-
27744605161
-
131I]meta-iodobenzylguanidine and topotecan combination treatment of tumors expressing the noradrenaline transporter
-
131I]meta- iodobenzylguanidine and topotecan combination treatment of tumors expressing the noradrenaline transporter. Clin Cancer Res. 2005;11:7929-7937.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7929-7937
-
-
McCluskey, A.G.1
Boyd, M.2
Ross, S.C.3
-
21
-
-
0031059777
-
Incorporation of iododeoxyuridine in multicellular glioma spheroids: Implications for DNA-targeted radiotherapy using Auger electron emitters
-
Neshasteh-Riz A, Angerson WJ, Reeves JR, Smith G, Rampling R, Mairs RJ. Incorporation of iododeoxyuridine in multicellular glioma spheroids: implications for DNA-targeted radiotherapy using Auger electron emitters. Br J Cancer. 1997;75:493-499. (Pubitemid 27085288)
-
(1997)
British Journal of Cancer
, vol.75
, Issue.4
, pp. 493-499
-
-
Neshasteh-Riz, A.1
Angerson, W.J.2
Reeves, J.R.3
Smith, G.4
Rampling, R.5
Mairs, R.J.6
-
23
-
-
0036726584
-
Transfectant mosaic spheroids: A new model for evaluation of tumour cell killing in targeted radiotherapy and experimental gene therapy
-
DOI 10.1002/jgm.293
-
Boyd M, Mairs SC, Stevenson K, Livingstone A. McCluskey AG, Ross SC and Mairs RJ. Transfectant mosaic spheroids: a new model for the evaluation of bystander effects in experimental gene therapy. J Gene Med. 2002;4:567-576. (Pubitemid 40268383)
-
(2002)
Journal of Gene Medicine
, vol.4
, Issue.5
, pp. 567-576
-
-
Boyd, M.1
Mairs, S.C.2
Stevenson, K.3
Livingstone, A.4
Clark, A.M.5
Ross, S.C.6
Mairs, R.J.7
-
24
-
-
0017726744
-
A simplified method for production and growth of multicellular tumor spheroids
-
Yuhas JM, Li AP, Martinez AO, Ladman AJ. A simplified method for production and growth of multicellular tumor spheroids. Cancer Res. 1977;37:3639-3643. (Pubitemid 8198426)
-
(1977)
Cancer Research
, vol.37
, Issue.10
, pp. 3639-3643
-
-
Yuhas, J.M.1
Li, A.P.2
Martinez, A.O.3
Ladman, A.J.4
-
25
-
-
0032697613
-
Growth and characterization of LNCaP prostate cancer cell spheroids
-
Ballangrud AM, Yang WH, Dnistrian A, Lampen NM, Sgouros G. Growth and characterization of LNCaP prostate cancer cell spheroids. Clin Cancer Res. 1999;5:3171s-3176s. (Pubitemid 29493912)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.10 SUPPL.
-
-
Ballangrud, A.M.1
Yang, W.-H.2
Dnistrian, A.3
Lampen, N.M.4
Sgouros, G.5
-
26
-
-
0021118703
-
Quantitative analysis of dose-effect relationship: The combined effects of multiple drugs or enzyme inhibitors
-
Chou TC, Talalay P. Quantitative analysis of dose-effect relationship: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul. 1984;22:27-55.
-
(1984)
Adv Enzyme Regul
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
27
-
-
33847668394
-
Image-based screening for the identification of novel proteasome inhibitors
-
DOI 10.1177/1087057106297115
-
Rickardson L, Wickstrom M, Larsson R, Lovborg H. Image-based screening for the identification of novel proteasome inhibitors. J Biomol Screen. 2007;12:203-210. (Pubitemid 46364423)
-
(2007)
Journal of Biomolecular Screening
, vol.12
, Issue.2
, pp. 203-210
-
-
Rickardson, L.1
Wickstrom, M.2
Larsson, R.3
Lovborg, H.4
-
28
-
-
0025338201
-
Cytotoxicity of diethyldithiocarbamate in human versus rodent cell lines
-
Cohen JD, Robins HI. Cytotoxicity of diethyldithiocarbamate in human versus rodent cell lines. Invest New Drugs. 1990;8:137-142. (Pubitemid 20184223)
-
(1990)
Investigational New Drugs
, vol.8
, Issue.2
, pp. 137-142
-
-
Cohen, J.D.1
Robins, H.I.2
-
29
-
-
0242718916
-
Novel biphasic effect of pyrrolidine dithiocarbamate on neuronal cell viability is mediated by the differential regulation of intracellular zinc and copper ion levels, NF-κB, and MAP kinases
-
DOI 10.1002/(SICI)1097-4547(20000101)59:1<117::AID
-
Chung KC, Park JH, Kim CH, et al. Novel biphasic effect of pyrrolidine dithiocarbamate on neuronal cell viability is mediated by the differential regulation of intracellular zinc and copper ion levels, NF-κB and MAP kinases. J Neurosci Res. 2000;59:117-125. (Pubitemid 30038871)
-
(2000)
Journal of Neuroscience Research
, vol.59
, Issue.1
, pp. 117-125
-
-
Chung, K.C.1
Park, J.H.2
Kim, C.H.3
Hyun, W.L.4
Sato, N.5
Uchiyama, Y.6
Ahn, Y.S.7
-
30
-
-
0018164729
-
Radioactive and nonradioactive methods for the in vivo determinationof disulfiram, diethyldithiocarbamate and diethyldithiocarbamate-methyl ester
-
Faiman MD, Dodd DE, Minor SS, Hanzlik R. Radioactive and nonradioactive methods for the in vivo determination of disulfiram, diethyldithiocarbamate, and diethyldithiocarbamate-methyl ester. Alcohol Clin Exp Res. 1978;2:366-369. (Pubitemid 9072611)
-
(1978)
Alcoholism: Clinical and Experimental Research
, vol.2
, Issue.4
, pp. 366-369
-
-
Faiman, M.D.1
Dodd, D.E.2
Minor, S.S.3
Hanzlik, R.4
-
32
-
-
78049278346
-
Fetal bovine serum requirement for pyrridoline dithiocarbamate-induced apoptotic cell death of MCF-7 breast tumor cells
-
Oh H, Bang JS, Choi HM, Yang HI, Yoo MC, Kim KS. Fetal bovine serum requirement for pyrridoline dithiocarbamate-induced apoptotic cell death of MCF-7 breast tumor cells. Eur J Pharmacol. 2010;649:135-139.
-
(2010)
Eur J Pharmacol
, vol.649
, pp. 135-139
-
-
Oh, H.1
Bang, J.S.2
Choi, H.M.3
Yang, H.I.4
Yoo, M.C.5
Kim, K.S.6
-
33
-
-
11144224746
-
Disulfiram facilitates intracellular Cu uptake and induces apoptosis in human melanoma cells
-
DOI 10.1021/jm049568z
-
Cen D, Brayton D, Shahandeh B, Meyskens FL Jr, Farmer PJ. Disulfiram facilitates intracellular Cu uptake and induces apoptosis in human melanoma cells. J Med Chem. 2004;47:6914-6920. (Pubitemid 40053779)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.27
, pp. 6914-6920
-
-
Cen, D.1
Brayton, D.2
Shahandeh, B.3
Meyskens Jr., F.L.4
Farmer, P.J.5
-
34
-
-
0019167208
-
Trace metal levels in commercially prepared tissue culture media
-
DOI 10.1016/0040-8166(80)90016-6
-
Glassman AB, Rydzewski RS, Bennett CE. Trace metal levels in commercially prepared tissue culture medium. Tissue Cell. 1980;12:613-617. (Pubitemid 11185325)
-
(1980)
Tissue and Cell
, vol.12
, Issue.4
, pp. 613-617
-
-
Glassman, A.B.1
Rydzewski, R.S.2
Bennett, C.E.3
-
35
-
-
42149187107
-
Evaluation of copper-dependent proteasome-inhibitory and apoptosis-inducing activities of novel pyrrolidine dithiocarbamate analogues
-
Yu Z, Wang F, Milacic V, et al. Evaluation of copper-dependent proteasome-inhibitory and apoptosis-inducing activities of novel pyrrolidine dithiocarbamate analogues. Int J Mol Med. 2007;20:919-925.
-
(2007)
Int J Mol Med
, vol.20
, pp. 919-925
-
-
Yu, Z.1
Wang, F.2
Milacic, V.3
-
36
-
-
0018584053
-
Serum levels of selenium, calcium, copper magnesium, manganese and zinc in various human diseases
-
Sullivan JF, Blotcky AJ, Jetton MM, Hahn HK, Burch RE. Serum levels of selenium, calcium, copper, magnesium, manganese and zinc in various human diseases. J Nutr. 1979;109:1432-1437. (Pubitemid 9241700)
-
(1979)
Journal of Nutrition
, vol.109
, Issue.8
, pp. 1432-1437
-
-
Sullivan, J.F.1
Blotcky, A.J.2
Jetton, M.M.3
-
37
-
-
0021261634
-
Enzyme inhibition as a possible mechanism of the mutagenicity of dithiocarbamic acid derivatives in Salmonella typhimurium
-
DOI 10.1016/0009-2797(84)90106-6
-
Rannug A, Rannug U. Enzyme inhibition as a possible mechanism of the mutagenicity of dithiocarbamate acid derivatives in Salmonella typhimurium. Chem Biol Interact. 1984;49:329-340. (Pubitemid 14104884)
-
(1984)
Chemico-Biological Interactions
, vol.49
, Issue.3
, pp. 329-340
-
-
Rannug, A.1
Rannug, U.2
|