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Volumn 38, Issue 2, 2014, Pages 181-189

Si-DNMT1 restore tumor suppressor genes expression through the reversal of DNA hypermethylation in cholangiocarcinoma

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CADHERIN; CADHERIN 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; DNA METHYLTRANSFERASE 1; PLASMID VECTOR; PROTEIN; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1; SI DNMT1; UNCLASSIFIED DRUG; DMAP1 PROTEIN, HUMAN; RASSF1 PROTEIN, HUMAN; REPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

EID: 84899487410     PISSN: 22107401     EISSN: 2210741X     Source Type: Journal    
DOI: 10.1016/j.clinre.2013.11.004     Document Type: Article
Times cited : (16)

References (34)
  • 1
    • 55049122566 scopus 로고    scopus 로고
    • Proximal biliary malignancy
    • Akoad M., Jenkins R. Proximal biliary malignancy. Surg Clin North Am 2008, 88:1409-1428.
    • (2008) Surg Clin North Am , vol.88 , pp. 1409-1428
    • Akoad, M.1    Jenkins, R.2
  • 3
    • 78651353583 scopus 로고    scopus 로고
    • Methyl-CpG binding protein MBD2 is implicated in methylation-mediated suppression of miR-373 in hilar cholangiocarcinoma
    • Chen Y., Gao W., Luo J., Tian R., Sun H., Zou S. Methyl-CpG binding protein MBD2 is implicated in methylation-mediated suppression of miR-373 in hilar cholangiocarcinoma. Oncol Rep 2011, 25:443-451.
    • (2011) Oncol Rep , vol.25 , pp. 443-451
    • Chen, Y.1    Gao, W.2    Luo, J.3    Tian, R.4    Sun, H.5    Zou, S.6
  • 4
    • 84863175288 scopus 로고    scopus 로고
    • Decreased expression of retinoblastoma protein-interacting zinc-finger gene 1 in human esophageal squamous cell cancer by DNA methylation
    • Dong S.W., Cui Y.T., Zhong R.R., Liang D.C., Liu Y.M., Wang Y.G., et al. Decreased expression of retinoblastoma protein-interacting zinc-finger gene 1 in human esophageal squamous cell cancer by DNA methylation. Clin Lab 2012, 58:41-51.
    • (2012) Clin Lab , vol.58 , pp. 41-51
    • Dong, S.W.1    Cui, Y.T.2    Zhong, R.R.3    Liang, D.C.4    Liu, Y.M.5    Wang, Y.G.6
  • 5
    • 77957986529 scopus 로고    scopus 로고
    • Epigenetic alteration of the Wnt inhibitory factor-1 promoter is common and occurs in advanced stage of Tunisian nasopharyngeal carcinoma
    • Fendri A., Khabir A., Hadri-Guiga B., Sellami-Boudawara T., Daoud J., Frikha M., et al. Epigenetic alteration of the Wnt inhibitory factor-1 promoter is common and occurs in advanced stage of Tunisian nasopharyngeal carcinoma. Cancer Invest 2010, 28:896-903.
    • (2010) Cancer Invest , vol.28 , pp. 896-903
    • Fendri, A.1    Khabir, A.2    Hadri-Guiga, B.3    Sellami-Boudawara, T.4    Daoud, J.5    Frikha, M.6
  • 6
    • 79960611738 scopus 로고    scopus 로고
    • Quantitative analysis and diagnostic significance of methylated SLC19A3 DNA in the plasma of breast and gastric cancer patients
    • Ng E.K., Leung C.P., Shin V.Y., Wong C.L., Ma E.S., Jin H.C., et al. Quantitative analysis and diagnostic significance of methylated SLC19A3 DNA in the plasma of breast and gastric cancer patients. PLoS One 2011, 6:e22233.
    • (2011) PLoS One , vol.6
    • Ng, E.K.1    Leung, C.P.2    Shin, V.Y.3    Wong, C.L.4    Ma, E.S.5    Jin, H.C.6
  • 8
    • 79951958851 scopus 로고    scopus 로고
    • CpG island methylator phenotype of cell-cycle regulators associated with TNM stage and poor prognosis in patients with oesophageal squamous cell carcinoma
    • Ling Y., Huang G., Fan L., Wei L., Zhu J., Liu Y., et al. CpG island methylator phenotype of cell-cycle regulators associated with TNM stage and poor prognosis in patients with oesophageal squamous cell carcinoma. J Clin Pathol 2011, 64:246-251.
    • (2011) J Clin Pathol , vol.64 , pp. 246-251
    • Ling, Y.1    Huang, G.2    Fan, L.3    Wei, L.4    Zhu, J.5    Liu, Y.6
  • 9
    • 67349188229 scopus 로고    scopus 로고
    • Preferentially different mechanisms of inactivation of 9p21 gene cluster in liver fluke-related cholangiocarcinoma
    • Chinnasri P., Pairojkul C., Jearanaikoon P., Sripa B., Bhudhisawasdi V., Tantimavanich S., et al. Preferentially different mechanisms of inactivation of 9p21 gene cluster in liver fluke-related cholangiocarcinoma. Hum Pathol 2009, 40:817-826.
    • (2009) Hum Pathol , vol.40 , pp. 817-826
    • Chinnasri, P.1    Pairojkul, C.2    Jearanaikoon, P.3    Sripa, B.4    Bhudhisawasdi, V.5    Tantimavanich, S.6
  • 10
    • 0036056617 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations of the INK4a-ARF pathway in cholangiocarcinoma
    • Tannapfel A., Sommerer F., Benicke M., Weinans L., Katalinic A., Geissler F., et al. Genetic and epigenetic alterations of the INK4a-ARF pathway in cholangiocarcinoma. J Pathol 2002, 197:624-631.
    • (2002) J Pathol , vol.197 , pp. 624-631
    • Tannapfel, A.1    Sommerer, F.2    Benicke, M.3    Weinans, L.4    Katalinic, A.5    Geissler, F.6
  • 12
    • 76149096516 scopus 로고    scopus 로고
    • Methylation associated inactivation of RASSF1 and its synergistic effect with activated K-Ras in nasopharyngeal carcinoma
    • Wang T., Liu H., Chen Y., Liu W., Yu J., Wu G. Methylation associated inactivation of RASSF1 and its synergistic effect with activated K-Ras in nasopharyngeal carcinoma. J Exp Clin Cancer Res 2009, 28:160.
    • (2009) J Exp Clin Cancer Res , vol.28 , pp. 160
    • Wang, T.1    Liu, H.2    Chen, Y.3    Liu, W.4    Yu, J.5    Wu, G.6
  • 13
    • 34247265566 scopus 로고    scopus 로고
    • Identification of epigenetic aberrant promoter methylation of RASSF1 in serum DNA and its clinicopathological significance in lung cancer
    • Wang Y., Yu Z., Wang T., Zhang J., Hong L., Chen L. Identification of epigenetic aberrant promoter methylation of RASSF1 in serum DNA and its clinicopathological significance in lung cancer. Lung Cancer 2007, 56:289-294.
    • (2007) Lung Cancer , vol.56 , pp. 289-294
    • Wang, Y.1    Yu, Z.2    Wang, T.3    Zhang, J.4    Hong, L.5    Chen, L.6
  • 14
    • 0036845755 scopus 로고    scopus 로고
    • Frequent loss of chromosome 3p and hypermethylation of RASSF1 in cholangiocarcinoma
    • Wong N., Li L., Tsang K., Lai P.B., To K.F., Johnson P.J. Frequent loss of chromosome 3p and hypermethylation of RASSF1 in cholangiocarcinoma. J Hepatol 2002, 37:633-639.
    • (2002) J Hepatol , vol.37 , pp. 633-639
    • Wong, N.1    Li, L.2    Tsang, K.3    Lai, P.B.4    To, K.F.5    Johnson, P.J.6
  • 15
    • 34250171225 scopus 로고    scopus 로고
    • Methylation profiles of multiple CpG island loci in extrahepatic cholangiocarcinoma versus those of intrahepatic cholangiocarcinomas
    • Kim B.H., Cho N.Y., Choi M., Lee S., Jang J.J., Kang G.H. Methylation profiles of multiple CpG island loci in extrahepatic cholangiocarcinoma versus those of intrahepatic cholangiocarcinomas. Arch Pathol Lab Med 2007, 131:923-930.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 923-930
    • Kim, B.H.1    Cho, N.Y.2    Choi, M.3    Lee, S.4    Jang, J.J.5    Kang, G.H.6
  • 16
    • 15444375859 scopus 로고    scopus 로고
    • Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma
    • Yang B., House M.G., Guo M., Herman J.G., Clark D.P. Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma. Mod Pathol 2005, 18:412-420.
    • (2005) Mod Pathol , vol.18 , pp. 412-420
    • Yang, B.1    House, M.G.2    Guo, M.3    Herman, J.G.4    Clark, D.P.5
  • 17
    • 33745213611 scopus 로고    scopus 로고
    • Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues
    • Arai E., Kanai Y., Ushijima S., Fujimoto H., Mukai K., Hirohashi S. Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues. Int J Cancer 2006, 119:288-296.
    • (2006) Int J Cancer , vol.119 , pp. 288-296
    • Arai, E.1    Kanai, Y.2    Ushijima, S.3    Fujimoto, H.4    Mukai, K.5    Hirohashi, S.6
  • 18
    • 80051644174 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors reverse CpG methylation by regulating DNMT1 through ERK signaling
    • Sarkar S., Abujamra A.L., Loew J.E., Forman L.W., Perrine S.P., Faller D.V. Histone deacetylase inhibitors reverse CpG methylation by regulating DNMT1 through ERK signaling. Anticancer Res 2011, 31:2723-2732.
    • (2011) Anticancer Res , vol.31 , pp. 2723-2732
    • Sarkar, S.1    Abujamra, A.L.2    Loew, J.E.3    Forman, L.W.4    Perrine, S.P.5    Faller, D.V.6
  • 19
    • 77956661140 scopus 로고    scopus 로고
    • Reduction of pancreatic cancer cell viability and induction of apoptosis mediated by siRNA targeting DNMT1 through suppression of total DNA methyltransferase activity
    • Xu M., Gao J., Du Y.Q., Gao D.J., Zhang Y.Q., Li Z.S., et al. Reduction of pancreatic cancer cell viability and induction of apoptosis mediated by siRNA targeting DNMT1 through suppression of total DNA methyltransferase activity. Mol Med Report 2010, 3:699-704.
    • (2010) Mol Med Report , vol.3 , pp. 699-704
    • Xu, M.1    Gao, J.2    Du, Y.Q.3    Gao, D.J.4    Zhang, Y.Q.5    Li, Z.S.6
  • 20
    • 0036712913 scopus 로고    scopus 로고
    • Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells
    • Tao Q., Huang H., Geiman T.M., Lim C.Y., Fu L., Qiu G.H., et al. Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells. Hum Mol Genet 2002, 11:2091-2102.
    • (2002) Hum Mol Genet , vol.11 , pp. 2091-2102
    • Tao, Q.1    Huang, H.2    Geiman, T.M.3    Lim, C.Y.4    Fu, L.5    Qiu, G.H.6
  • 21
    • 34648830896 scopus 로고    scopus 로고
    • Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor
    • Nasimuzzaman M., Waris G., Mikolon D., Stupack D.G., Siddiqui A. Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor. J Virol 2007, 81:10249-10257.
    • (2007) J Virol , vol.81 , pp. 10249-10257
    • Nasimuzzaman, M.1    Waris, G.2    Mikolon, D.3    Stupack, D.G.4    Siddiqui, A.5
  • 22
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 2007, 8:286-298.
    • (2007) Nat Rev Genet , vol.8 , pp. 286-298
    • Esteller, M.1
  • 23
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M. Epigenetics in cancer. N Engl J Med 2008, 358:1148-1159.
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 24
    • 37449033470 scopus 로고    scopus 로고
    • Epigenetic DNA hypermethylation in cholangiocarcinoma: potential roles in pathogenesis, diagnosis and identification of treatment targets
    • Sandhu D.S., Shire A.M., Roberts L.R. Epigenetic DNA hypermethylation in cholangiocarcinoma: potential roles in pathogenesis, diagnosis and identification of treatment targets. Liver Int 2008, 28:12-27.
    • (2008) Liver Int , vol.28 , pp. 12-27
    • Sandhu, D.S.1    Shire, A.M.2    Roberts, L.R.3
  • 25
    • 33749985758 scopus 로고    scopus 로고
    • Structure, function and mechanism of exocyclic DNA methyltransferases
    • Bheemanaik S., Reddy Y.V., Rao D.N. Structure, function and mechanism of exocyclic DNA methyltransferases. Biochem J 2006, 399:177-190.
    • (2006) Biochem J , vol.399 , pp. 177-190
    • Bheemanaik, S.1    Reddy, Y.V.2    Rao, D.N.3
  • 26
    • 4444325603 scopus 로고    scopus 로고
    • Demethylation of DNA by decitabine in cancer chemotherapy
    • Brown R., Plumb J.A. Demethylation of DNA by decitabine in cancer chemotherapy. Expert Rev Anticancer Ther 2004, 4:501-510.
    • (2004) Expert Rev Anticancer Ther , vol.4 , pp. 501-510
    • Brown, R.1    Plumb, J.A.2
  • 27
    • 0037108309 scopus 로고    scopus 로고
    • Demethylation of a hypermethylated CDKN2B/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment
    • Daskalakis M., Nguyen T.T., Nguyen C., Guldberg P., Köhler G., Wijermans P., et al. Demethylation of a hypermethylated CDKN2B/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment. Blood 2002, 100:2957-2964.
    • (2002) Blood , vol.100 , pp. 2957-2964
    • Daskalakis, M.1    Nguyen, T.T.2    Nguyen, C.3    Guldberg, P.4    Köhler, G.5    Wijermans, P.6
  • 28
    • 1242329250 scopus 로고    scopus 로고
    • 5-Aza-2'-deoxycitydine induces demethylation and up-regulates transcription of CDKN2AINK4A gene in human gastric cancer cell lines
    • Fang J.Y., Yang L., Zhu H.Y., Chen Y.X., Lu J., Lu R., et al. 5-Aza-2'-deoxycitydine induces demethylation and up-regulates transcription of CDKN2AINK4A gene in human gastric cancer cell lines. Chin Med J (Engl) 2004, 117:99-103.
    • (2004) Chin Med J (Engl) , vol.117 , pp. 99-103
    • Fang, J.Y.1    Yang, L.2    Zhu, H.Y.3    Chen, Y.X.4    Lu, J.5    Lu, R.6
  • 29
    • 37349036468 scopus 로고    scopus 로고
    • DNA methyltransferase 1 knockdown induces silenced CDH1 gene reexpression by demethylation of methylated CpG in hepatocellular carcinoma cell line SMMC-7721
    • Fan H., Zhao Z., Quan Y., Xu J., Zhang J., Xie W. DNA methyltransferase 1 knockdown induces silenced CDH1 gene reexpression by demethylation of methylated CpG in hepatocellular carcinoma cell line SMMC-7721. Eur J Gastroenterol Hepatol 2007, 19:952-961.
    • (2007) Eur J Gastroenterol Hepatol , vol.19 , pp. 952-961
    • Fan, H.1    Zhao, Z.2    Quan, Y.3    Xu, J.4    Zhang, J.5    Xie, W.6
  • 30
    • 34748835339 scopus 로고    scopus 로고
    • Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy
    • Jung Y., Park J., Kim T.Y., Park J.H., Jong H.S., Im S.A., et al. Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy. J Mol Med (Berl) 2007, 85:1137-1148.
    • (2007) J Mol Med (Berl) , vol.85 , pp. 1137-1148
    • Jung, Y.1    Park, J.2    Kim, T.Y.3    Park, J.H.4    Jong, H.S.5    Im, S.A.6
  • 31
    • 33846607782 scopus 로고    scopus 로고
    • A DNA methylation-based switch generates bistable gene expression
    • Bennett M.R., Hasty J. A DNA methylation-based switch generates bistable gene expression. Nat Genet 2007, 39:146-147.
    • (2007) Nat Genet , vol.39 , pp. 146-147
    • Bennett, M.R.1    Hasty, J.2
  • 32
    • 4644328089 scopus 로고    scopus 로고
    • Chromosomal regulation by MeCP2: structural and enzymatic considerations
    • Bowen N.J., Palmer M.B., Wade P.A. Chromosomal regulation by MeCP2: structural and enzymatic considerations. Cell Mol Life Sci 2004, 61:2163-2167.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2163-2167
    • Bowen, N.J.1    Palmer, M.B.2    Wade, P.A.3
  • 33
    • 60349109571 scopus 로고    scopus 로고
    • DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers
    • Ying J., Poon F.F., Yu J., Geng H., Wong A.H., Qiu G.H., et al. DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers. Br J Cancer 2009, 100:663-669.
    • (2009) Br J Cancer , vol.100 , pp. 663-669
    • Ying, J.1    Poon, F.F.2    Yu, J.3    Geng, H.4    Wong, A.H.5    Qiu, G.H.6
  • 34
    • 40049093415 scopus 로고    scopus 로고
    • Regulation of demethylation and re-expression of RASSF1 gene in gastric cancer cell lines by combined treatment of 5-Aza-CdR and NaB
    • Shen W.J., Dai D.Q., Teng Y., Liu H.B. Regulation of demethylation and re-expression of RASSF1 gene in gastric cancer cell lines by combined treatment of 5-Aza-CdR and NaB. World J Gastroenterol 2008, 14:595-600.
    • (2008) World J Gastroenterol , vol.14 , pp. 595-600
    • Shen, W.J.1    Dai, D.Q.2    Teng, Y.3    Liu, H.B.4


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