Bioretrosynthetic construction of a didanosine biosynthetic pathway

Nature Chemical Biology

Volumn 10, Issue 5, 2014, Pages 392-399

  Birmingham, William R ^a,c   Starbird, Chrystal A ^a   Panosian, Timothy D ^a,d   Nannemann, David P ^b,e   Iverson, T M ^a   Bachmann, Brian O ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d MONSANTO COMPANY   (United States)

^e EMD SERONO INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,5 PHOSPHOPENTOMUTASE; 2,3 DIDEOXYRIBOSE 5 PHOSPHATE; DEOXYRIBOSE; DIDANOSINE; MUTASE; NUCLEOSIDE; PURINE NUCLEOSIDE PHOSPHORYLASE; UNCLASSIFIED DRUG;

ARTICLE; BIOCATALYST; CELL LYSATE; DRUG SYNTHESIS; ENZYME ENGINEERING; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL;

BIOCATALYSIS; DIDANOSINE; DIRECTED MOLECULAR EVOLUTION; ENZYMES; MODELS, MOLECULAR;

EID: 84899486357     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1494     Document Type: Article

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