Ratio of n-3/n-6 PUFAs and risk of breast cancer: A meta-analysis of 274135 adult females from 11 independent prospective studies

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Yang, Bo ^a,b   Ren, Xiao Li ^b   Fu, Yuan Qin ^a   Gao, Jin Long ^a   Li, Duo ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

OMEGA 3 FATTY ACID; PHOSPHOLIPID; OMEGA 6 FATTY ACID;

ADULT; ARTICLE; BREAST CANCER; CANCER PREVENTION; CANCER RISK; CASE CONTROL STUDY; CLINICAL EFFECTIVENESS; COHORT ANALYSIS; DIET SUPPLEMENTATION; EVIDENCE BASED MEDICINE; FAT INTAKE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; META ANALYSIS; PHOSPHOLIPID BLOOD LEVEL; PROSPECTIVE STUDY; RISK REDUCTION; FATTY ACID BLOOD LEVEL; FOLLOW UP; LIPID COMPOSITION; NUTRITIONAL PARAMETERS; OMEGA 3 OMEGA 6 FATTY ACID RATIO; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; SYSTEMATIC REVIEW; THERAPY EFFECT; BLOOD; BREAST NEOPLASMS; DIET; METABOLISM; PUBLISHING; RISK;

BREAST NEOPLASMS; DIET; FATTY ACIDS, OMEGA-3; FEMALE; HUMANS; ODDS RATIO; PROSPECTIVE STUDIES; PUBLICATION BIAS; RISK;

EID: 84899480460     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-105     Document Type: Article

References (47)

1. Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001, 94(2):153-156. 10.1002/ijc.1440, 11668491.
2. Bhoo-Pathy N, Yip CH, Hartman M, Uiterwaal CS, Devi BC, Peeters PH, Taib NA, van Gils CH, Verkooijen HM. Breast cancer research in Asia: adopt or adapt Western knowledge?. Eur J Cancer 2013, 49(3):703-709. 10.1016/j.ejca.2012.09.014, 23040889.
3. Shimizu H, Ross RK, Bernstein L, Yatani R, Henderson BE, Mack TM. Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County. Br J Cancer 1991, 63(6):963-966. 10.1038/bjc.1991.210, 1972548, 2069852.
4. Kim EH, Willett WC, Colditz GA, Hankinson SE, Stampfer MJ, Hunter DJ, Rosner B, Holmes MD. Dietary fat and risk of postmenopausal breast cancer in a 20-year follow-up. Am J Epidemiol 2006, 164(10):990-997. 10.1093/aje/kwj309, 16968865.
5. Zhang CX, Ho SC, Lin FY, Chen YM, Cheng SZ, Fu JH. Dietary fat intake and risk of breast cancer: A case-control study in China. Eur J Cancer Prev 2011, 20(3):199-206. 10.1097/CEJ.0b013e32834572bb, 21403522.
6. MacLennan M, Ma DWL. Role of dietary fatty acids in mammary gland development and breast cancer. Breast Cancer Res 2010, 12(5):211-221. 10.1186/bcr2646, 3096965, 21067551.
7. Karmali RA. Eicosanoids in neoplasia. Prev Med 1987, 16(4):493-502. 10.1016/0091-7435(87)90063-6, 3114735.
8. Wen ZH, Su YC, Lai PL, Zhang Y, Xu YF, Zhao A, Yao GY, Jia CH, Lin J, Xu S, Wang L, Wang XK, Liu AL, Jiang Y, Dai YF, Bai XC. Critical role of arachidonic acid-activated mTOR signaling in breast carcinogenesis and angiogenesis. Oncogene 2013, 32(2):160-170. 10.1038/onc.2012.47, 22349822.
9. Vendramini-Costa DB, Carvalho JE. Molecular link mechanisms between inflammation and cancer. Curr Pharm Des 2012, 18(26):3831-3852. 10.2174/138161212802083707, 22632748.
10. Chamras H, Ardashian A, Heber D, Glaspy JA. Fatty acid modulation of MCF-7 human breast cancer cell proliferation, apoptosis and differentiation. J Nutr Biochem 2002, 13(12):711-716. 10.1016/S0955-2863(02)00230-9, 12550055.
11. Stillwell W, Shaikh SR, Zerouga M, Siddiqui R, Wassall SR. Docosahexaenoic acid affects cell signaling by altering lipid rafts. Reprod Nutr Dev 2005, 45(5):559-579. 10.1051/rnd:2005046, 16188208.
12. Shannon J, King IB, Lampe JW, Gao DL, Ray RM, Lin MG, Stalsberg H, Thomas DB. Erythrocyte fatty acids and risk of proliferative and nonproliferative fibrocystic disease in women in Shanghai. China. Am J Clin Nutr 2009, 89(1):265-276.
13. Kuriki K, Hirose K, Wakai K, Matsuo K, Ito H, Suzuki T, Hiraki A, Saito T, Iwata H, Tatematsu M, Tajima K. Breast cancer risk and erythrocyte compositions of n-3 highly unsaturated fatty acids in Japanese. Int J Cancer 2007, 121(2):377-385. 10.1002/ijc.22682, 17354239.
14. Maillard V, Bougnoux P, Ferrari P, Jourdan ML, Pinault M, Lavillonniere F, Body G, Le Floch O, Chajes V. N-3 and N-6 fatty acids in breast adipose tissue and relative risk of breast cancer in a case-control study in Tours. France. Int J Cancer 2002, 98(1):78-83.
15. Park SY, Kolonel LN, Henderson BE, Wilkens LR. Dietary fat and breast cancer in postmenopausal women according to ethnicity and hormone receptor status: the multiethnic cohort study. Cancer Prev Res (Phila) 2012, 5(2):216-228. 10.1158/1940-6207.CAPR-11-0260, 22166249.
16. Murff HJ, Shu XO, Li HL, Yang G, Wu XY, Cai H, Wen WQ, Gao YT, Zheng W. Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: a prospective cohort study. Int J Cancer 2011, 128(6):1434-1441. 10.1002/ijc.25703, 3086389, 20878979.
17. Wakai K, Tamakoshi K, Date C, Fukui M, Suzuki S, Lin Y, Niwa Y, Nishio K, Yatsuya H, Kondo T, Tokudome S, Yamamoto A, Toyoshima H, Tamakoshi A, JACC Study Group Dietary intakes of fat and fatty acids and risk of breast cancer: A prospective study in Japan. Cancer Sci 2005, 96(9):590-599. 10.1111/j.1349-7006.2005.00084.x, 16128744, JACC Study Group.
18. Vatten LJ, Bjerve KS, Andersen A, Jellum E. Polyunsaturated fatty acids in serum phospholipids and risk of breast cancer: a case-control study from the Janus serum bank in Norway. Eur J Cancer 1993, 29A(4):532-538.
19. Saadatian-Elahi M, Toniolo P, Ferrari P, Goudable J, Akhmedkhanov A, Zeleniuch-Jacquotte A, Riboli E. Serum fatty acids and risk of breast cancer in a nested case-control study of the New York University Women's Health Study. Cancer Epidem Biomar 2002, 11(11):1353-1360.
20. Chajes V, Thiebaut ACM, Rotival M, Gauthier E, Maillard V, Boutron-Ruault MC, Joulin V, Lenoir GM, Clavel-Chapelon F. Association between serum trans-monounsaturated fatty acids and breast cancer risk in the E3N-EPIC study. Am J Epidemiol 2008, 167(11):1312-1320. 10.1093/aje/kwn069, 2679982, 18390841.
21. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, Moher D, Becker BJ, Sipe TA, Thacker SB. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000, 283(15):2008-2012. 10.1001/jama.283.15.2008, 10789670.
22. Wells GA SB, O'Connell D, Peterson J, Welch V, Losos M. The Newcastle-Ottawa Scale (NOS) for assessing the quality of non randomized studies in meta-analyses 2011, http://www.ohri.ca/programs/clinical_epidemiology/oxford.htm. Accessed Novenber 21, 2012.
23. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986, 7(3):177-188. 10.1016/0197-2456(86)90046-2, 3802833.
24. Greenland S, Longnecker MP. Methods for trend estimation from summarized dose-response data, with applications to meta-analysis. Am J Epidemiol 1992, 135(11):1301-1309.
25. Orsini N, Bellocco R, Greenland S. Generalized least squares for trend estimation of summarized dose-response data. Stata J 2006, 6(1):40-57.
26. Larsson SC, Orsini N, Wolk A. Vitamin B6 and risk of colorectal cancer: a meta-analysis of prospective studies. JAMA 2010, 303(11):1077-1083. 10.1001/jama.2010.263, 20233826.
27. Harrell FE, Lee KL, Pollock BG. Regression models in clinical studies: determining relationships between predictors and response. J Natl Cancer Inst 1988, 80(15):1198-1202. 10.1093/jnci/80.15.1198, 3047407.
28. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003, 327(7414):557-560. 10.1136/bmj.327.7414.557, 192859, 12958120.
29. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997, 315(7109):629-634. 10.1136/bmj.315.7109.629, 2127453, 9310563.
30. Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L. Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetry. J Clin Epidemiol 2008, 61(10):991-996. 10.1016/j.jclinepi.2007.11.010, 18538991.
31. Duval S, Tweedie R. Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 2000, 56(2):455-463. 10.1111/j.0006-341X.2000.00455.x, 10877304.
32. Thiebaut AC, Chajes V, Gerber M, Boutron-Ruault MC, Joulin V, Lenoir G, Berrino F, Riboli E, Benichou J, Clavel-Chapelon F. Dietary intakes of omega-6 and omega-3 polyunsaturated fatty acids and the risk of breast cancer. Int J Cancer 2009, 124:924-931. 2008/11/28 edn, 10.1002/ijc.23980, 19035453.
33. Sczaniecka AK, Brasky TM, Lampe JW, Patterson RE, White E. Dietary intake of specific fatty acids and breast cancer risk among postmenopausal women in the VITAL cohort. Nutrition and cancer 2012, 64(8):1131-1142. 10.1080/01635581.2012.718033, 3633593, 23137008.
34. Chajes V, Hulten K, Van Kappel AL, Winkvist A, Kaaks R, Hallmans G, Lenner PG, Riboli E. Fatty-acid composition in serum phospholipids and risk of breast cancer: an incident case-control study in Sweden. Int J Cancer 1999, 83(5):585-590. 10.1002/(SICI)1097-0215(19991126)83:5<585::AID-IJC2>3.0.CO;2-Z, 10521790.
35. Wirfalt E, Mattisson I, Gullberg B, Johansson U, Olsson H, Berglund G. Postmenopausal breast cancer is associated with high intakes of (omega)6 fatty acids (Sweden). Cancer Causes Control 2002, 13(10):883-893. 10.1023/A:1021922917489, 12588084.
36. Takata Y, King IB, Neuhouser ML, Schaffer S, Barnett M, Thornquist M, Peters U, Goodman GE. Association of serum phospholipid fatty acids with breast cancer risk among postmenopausal cigarette smokers. Cancer Cause Control 2009, 20(4):497-504.
37. Simopoulos AP. The Mediterranean diets: What is so special about the diet of Greece? The scientific evidence. J Nutr 2001, 131(11 SUPPL):3065S-3073S.
38. Signori C, DuBrock C, Richie JP, Prokopczyk B, Demers LM, Hamilton C, Hartman TJ, Liao J, El-Bayoumy K, Manni A. Administration of omega-3 fatty acids and Raloxifene to women at high risk of breast cancer: interim feasibility and biomarkers analysis from a clinical trial. Eur J Clin Nutr 2012, 66(8):878-884. 10.1038/ejcn.2012.60, 22669332.
39. Reader J, Holt D, Fulton A. Prostaglandin E2 EP receptors as therapeutic targets in breast cancer. Cancer Metastasis Rev 2011, 30(3-4):449-463. 3640271, 22002714.
40. Hopkins GJ, Kennedy TG, Carroll KK. Polyunsaturated fatty acids as promoters of mammary carcinogenesis induced in Sprague-Dawley rats by 7,12-dimethylbenz[a]anthracene. J Natl Cancer Inst 1981, 66(3):517-522.
41. Grammatikos SI, Subbaiah PV, Victor TA, Miller WM. n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines. Br J Cancer 1994, 70(2):219-227. 10.1038/bjc.1994.283, 2033515, 8054269.
42. Rovito D, Giordano C, Vizza D, Plastina P, Barone I, Casaburi I, Lanzino M, De Amicis F, Sisci D, Mauro L, Aquila S, Catalano S, Bonofiglio D, Andò S. Omega-3 PUFA ethanolamides DHEA and EPEA induce autophagy through PPAR(gamma) activation in MCF-7 breast cancer cells. J Cell Physiol 2013, 228(6):1314-1322. 10.1002/jcp.24288, 23168911.
43. Rose DP, Connolly JM. Omega-3 fatty acids as cancer chemopreventive agents. Pharmacol Ther 1999, 83(3):217-244. 10.1016/S0163-7258(99)00026-1, 10576293.
44. Obata T, Nagakura T, Masaki T, Maekawa K, Yamashita K. Eicosapentaenoic acid inhibits prostaglandin D2 generation by inhibiting cyclo-oxygenase-2 in cultured human mast cells. Clin Exp Allergy 1999, 29(8):1129-1135. 10.1046/j.1365-2222.1999.00604.x, 10457118.
45. Hamid R, Singh J, Reddy BS, Cohen LA. Inhibition by dietary menhaden oil of cyclooxygenase-1 and 2 in N-nitrosomethylurea-induced rat mammary tumors. Int J Oncol 1999, 14(3):523-528.
46. Pietinen P, Vartiainen E, Seppanen R, Aro A, Puska P. Changes in diet in Finland from 1972 to 1992: Impact on coronary heart disease risk. Prev Med 1996, 25(3):243-250. 10.1006/pmed.1996.0053, 8781001.
47. Nettleton JA. Omega-3-fatty-acids - comparison of plant and seafood sources in human-nutrition. J Am Diet Assoc 1991, 91(3):331-337.